﻿<?xml version="1.0" encoding="UTF-8"?>
<difference>
   <type name="ResearchStudy" status="changed">
      <element binding-status="changed"
               binding-valueset-changed="true"
               path="ResearchStudy.status">
         <old-binding reference="http://hl7.org/fhir/ValueSet/research-study-status"
                      strength="required"/>
         <new-binding reference="http://hl7.org/fhir/ValueSet/research-study-status|4.0.1"
                      strength="required"/>
      </element>
      <element path="ResearchStudy.primaryPurposeType" status="new"/>
      <element path="ResearchStudy.phase" status="new"/>
      <element path="ResearchStudy.condition" status="new"/>
      <element path="ResearchStudy.location" status="new"/>
      <element path="ResearchStudy.principalInvestigator">
         <removed-type name="Reference(Practitioner)"/>
         <added-type name="Reference(Practitioner | PractitionerRole)"/>
      </element>
      <element path="ResearchStudy.arm.type" status="new"/>
      <element path="ResearchStudy.objective" status="new"/>
      <element path="ResearchStudy.objective.name" status="new"/>
      <element path="ResearchStudy.objective.type" status="new"/>
      <element path="ResearchStudy.jurisdiction" status="deleted"/>
      <element path="ResearchStudy.arm.code" status="deleted"/>
   </type>
</difference>
