# cliProfiler
Author: You Zhou, Kathi Zarnack
---
# Introduction
Cross-linking immunoprecipitation (CLIP) is a technique that combines UV
cross-linking and immunoprecipitation to analyse protein-RNA interactions or to
pinpoint RNA modifications (e.g. m6A). CLIP-based methods, such as iCLIP and
eCLIP, allow precise mapping of RNA modification sites or RNA-binding protein
(RBP) binding sites on a genome-wide scale. These techniques help us to unravel
post-transcriptional regulatory networks. In order to make the visualization of
CLIP data easier, we develop `r Biocpkg("cliProfiler")` package. The
`r Biocpkg("cliProfiler")` includes seven functions which allow users easily
make different profile plots.
The `r Biocpkg("cliProfiler")` package is available at
[https://bioconductor.org](https://bioconductor.org) and can be
installed via `BiocManager::install`:
```{r BiocManager, eval=FALSE}
if (!require("BiocManager"))
install.packages("BiocManager")
BiocManager::install("cliProfiler")
```
A package only needs to be installed once. Load the package into an
R session with
```{r initialize, results="hide", warning=FALSE, message=FALSE}
library(cliProfiler)
```
# How to use it
Documentation (vignette and user manual) is available at the **cliProfiler**
Bioconductor landing page at http://bioconductor.org/packages/cliProfiler.
