Pufferfish Venom Can Kill, Or It Can Relieve Pain

Tetrodotoxin (TTX) is best known as the neurotoxin of the puffer fish, though it also appears in a range of other marine species. You might remember it from an episode of The Simpsons involving a poorly prepared dish at a sushi restaurant. Indeed, it’s a potent thing, as ingesting even tiny amounts can lead to death in short order.

Given its fatal reputation, it might be the last thing you’d expect to be used in a therapeutic context. And yet, tetrodotoxin is proving potentially valuable as a treatment option for dealing with cancer-related pain. It’s a dangerous thing to play with, but it could yet hold promise where other pain relievers simply can’t deliver. Continue reading “Pufferfish Venom Can Kill, Or It Can Relieve Pain”

Hackaday Links Column Banner

Hackaday Links: December 14, 2025

Fix stuff, earn big awards? Maybe, if this idea for repair bounties takes off. The group is dubbed the FULU Foundation, for “Freedom from Unethical Limitations on Users,” and was co-founded by right-to-repair activist Kevin O’Reilly and perennial Big Tech thorn-in-the-side Louis Rossman. The operating model works a bit like the bug bounty system, but in reverse: FULU posts cash bounties on consumer-hostile products, like refrigerators that DRM their water filters or bricked thermostats. The bounty starts at $10,000, but can increase based on donations from the public. FULU will match those donations up to $10,000, potentially making a very rich pot for the person or team that fixes the problem.

Continue reading “Hackaday Links: December 14, 2025”

User Serviceable Parts

Al and I were talking on the podcast about the Home Assistant home automation hub software. In particular, about how devilishly well designed it is for extensibility. It’s designed to be added on to, and that makes all of the difference.
That doesn’t mean that it’s trivial to add your own wacky control or sensor elements to the system, but that it’s relatively straightforward, and that it accommodates you. If your use case isn’t already covered, there is probably good documentation available to help guide you in the right direction, and that’s all a hacker really needs. As evidence for why you might care, take the RTL-HAOS project that we covered this week, which adds nearly arbitrary software-defined radio functionality to your setup.

And contrast this with many commercial systems that are hard to hack on because they are instead focused on making sure that the least-common-denominator user is able to get stuff working without even reading a single page of documentation. They are so focused on making everything that’s in-scope easy that they spend no thought on expansion, or worse they actively prevent it.

Of course, it’s not trivial to make a system that’s both extremely flexible and relatively easy to use. We all know examples where the configuration of even the most basic cases is a nightmare simply because the designer wanted to accommodate everything. Somehow, Home Assistant has managed to walk the fine line in the middle, where it’s easy enough to use that you don’t have to be a wizard, but that you can make it do what you want if you are, and hence it got spontaneous hat-tips from both Al and myself. Food for thought if you’re working on a complex system that’s aimed at the DIY / hacker crowd.

Hackaday Podcast Episode 349: Clocks, AI, And A New 3D Printer Guy

Hackaday Editors Elliot Williams and Al Williams met up to cover the best of Hackaday this week, and they want you to listen in. There were a hodgepodge of hacks this week, ranging from home automation with RF, volumetric displays in glass, and some crazy clocks, too.

Ever see a typewriter that uses an ink pen? Elliot and Al hadn’t either. Want time on a supercomputer? It isn’t free, but it is pretty cheap these days. Finally, the guys discussed how to focus on a project like Dan Maloney, who finally got a 3D printer, and talked about Maya Posch’s take on LLM intelligence.

Check out the links below if you want to follow along, and as always, tell us what you think about this episode in the comments!

Download the human-generated podcast in mostly mono, but sometimes stereo, MP3.

Continue reading “Hackaday Podcast Episode 349: Clocks, AI, And A New 3D Printer Guy”

This Week In Security: Hornet, Gogs, And Blinkenlights

Microsoft has published a patch-set for the Linux kernel, proposing the Hornet Linux Security Module (LSM). If you haven’t been keeping up with the kernel contributor scoreboard, Microsoft is #11 at time of writing and that might surprise you. The reality is that Microsoft’s biggest source of revenue is their cloud offering, and Azure is over half Linux, so Microsoft really is incentivized to make Linux better.

The Hornet LSM is all about more secure eBPF programs, which requires another aside: What is eBPF? First implemented in the Berkeley Packet Filter, it’s a virtual machine in the kernel, that allows executing programs in kernel space. It was quickly realized that this ability to run a script in kernel space was useful for far more than just filtering packets, and the extended Berkeley Packet Filter was born. eBPF is now used for load balancing, system auditing, security and intrusion detection, and lots more.

This unique ability to load scripts from user space into kernel space has made eBPF useful for malware and spyware applications, too. There is already a signature scheme to restrict eBPF programs, but Hornet allows for stricter checks and auditing. The patch is considered a Request For Comments (RFC), and points out that this existing protection may be subject to Time Of Check / Time Of Use (TOCTOU) attacks. It remains to be seen whether Hornet passes muster and lands in the upstream kernel. Continue reading “This Week In Security: Hornet, Gogs, And Blinkenlights”

Jenny’s Daily Drivers: Haiku R1/beta5

Back in the mid 1990s, the release of Microsoft’s Windows 95 operating system cemented the Redmond software company’s dominance over most of the desktop operating system space. Apple were still in their period in the doldrums waiting for Steve Jobs to return with his NeXT, while other would-be challengers such as IBM’s OS/2 or Commodore’s Amiga were sinking into obscurity.

Into this unpromising marketplace came Be inc, with their BeBox computer and its very nice BeOS operating system. To try it out as we did at a trade show some time in the late ’90s was to step into a very polished multitasking multimedia OS, but sadly one which failed to gather sufficient traction to survive. The story ended in the early 2000s as Be were swallowed by Palm, and a dedicated band of BeOS enthusiasts set about implementing a free successor OS. This has become Haiku, and while it’s not BeOS it retains API compatibility with and certainly feels a lot like its inspiration. It’s been on my list for a Daily Drivers article for a while now, so it’s time to download the ISO and give it a go. I’m using the AMD64 version.

Continue reading “Jenny’s Daily Drivers: Haiku R1/beta5”

FLOSS Weekly Episode 858: YottaDB: Sometimes The Solution Is Bigger Servers

This week Jonathan chats with K. S. Bhaskar about YottaDB. This very high performance database has some unique tricks! How does YottaDB run across multiple processes without a daemon? Why is it licensed AGPL, and how does that work with commercial deployments? Watch to find out!

Continue reading “FLOSS Weekly Episode 858: YottaDB: Sometimes The Solution Is Bigger Servers”