Compare the Top Advanced Threat Protection (ATP) Software for Mac as of July 2025

What is Advanced Threat Protection (ATP) Software for Mac?

Advanced threat protection (ATP) software is designed to detect, prevent, and respond to sophisticated cyber threats in real-time. It employs advanced techniques such as machine learning, behavioral analysis, and threat intelligence to identify and mitigate potential security risks. The software offers comprehensive protection across various endpoints, networks, and cloud environments, ensuring a multi-layered defense strategy. It also provides detailed reporting and analytics, enabling organizations to understand threat patterns and improve their security posture. By integrating these capabilities, advanced threat protection software helps organizations safeguard sensitive data, maintain regulatory compliance, and enhance overall cybersecurity resilience. Compare and read user reviews of the best Advanced Threat Protection (ATP) software for Mac currently available using the table below. This list is updated regularly.

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    ThreatLocker

    ThreatLocker

    ThreatLocker

    The ThreatLocker suite of security tools are powerful and designed so that everyone from businesses to government agencies to academic institutions can directly control exactly what applications run on their networks. We envision a future in which all organizations can chart their own course free from the influence of cybercriminals and the damage their incursions cause, and our team of veteran cybersecurity professionals created ThreatLocker to make this vision a reality. The team at ThreatLocker has been developing cybersecurity tools for decades, including programs to enhance email and content security, and this is our most innovative and ambitious cybersecurity solution yet. We developed this unique cybersecurity system because we believe that organizations should have complete control of their networks and should not have to live in fear of the next malware attack. To learn more, visit ThreatLocker.com.
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    ESET PROTECT Advanced
    ESET Protect Advanced is a comprehensive cybersecurity solution designed for businesses of all sizes. It offers advanced endpoint protection against ransomware, zero-day threats, and sophisticated attacks with ESET LiveSense technology. It includes full disk encryption for legal compliance and data protection. The solution features proactive cloud-based threat defense using adaptive scanning, machine learning, cloud sandboxing, and behavioral analysis to prevent new threats. Mobile threat defense secures Android and iOS devices with anti-malware, anti-theft, and mobile device management. It also provides cloud app protection, mail server security, and vulnerability and patch management. Extended detection and response (XDR) enhances threat detection and response, while multi-factor authentication adds security. The solution offers single-pane-of-glass remote management for visibility into threats and users, along with advanced reporting and custom notifications.
    Starting Price: $275/month/5 devices
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  • 3
    Trustifi

    Trustifi

    Trustifi

    Trustifi offers industry-leading solutions for email security that helps small, mid-size, and enterprise organizations manage threat detection, regulatory compliance, data encryption & more. Easily deployed on: Outlook, Gmail, or any email server by relay **Advanced Threat Protection**: -Malware and ransomware virus detection, BEC attack prevention and alerts **Data Loss Prevention**: -100% compliant with HIPAA/HITECH, PII, GDPR, FSA, FINRA, LGPD, CCPA, and more **Encryption**: -NSA-grade. Select Enterprise customers have access to company branding and product white labeling. Plus one-on-one team training. Encryption needs aren’t one-size-fits-all, so your email security platform shouldn’t be either. Customized solutions are available upon request, often without charge.
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    SentinelOne Singularity
    One intelligent platform. Unprecedented speed. Infinite scale. Singularity™ enables unfettered visibility, industry-leading detection, and autonomous response. Discover the power of AI-powered, enterprise-wide cybersecurity. The world’s leading enterprises use the Singularity platform to prevent, detect, and respond to cyber attacks at machine-speed, greater scale, and higher accuracy across endpoint, cloud, and identity. SentinelOne delivers cutting-edge security with this platform by offering protection against malware, exploits, and scripts. SentinelOne cloud-based platform has been perfected to be innovative compliant with security industry standards, and high-performance whether the work environment is Windows, Mac or Linux. Thanks to constant updating, threat hunting, and behavior AI, the platform is ready for any threat.
    Starting Price: $45 per user per year
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    Symantec Endpoint Protection
    Symantec Endpoint Security delivers the most complete, integrated endpoint security platform on the planet. As an on-premises, hybrid, or cloud-based solution, the single-agent Symantec platform protects all your traditional and mobile endpoint devices, and uses artificial intelligence (AI) to optimize security decisions. A unified cloud-based management system simplifies protecting, detecting and responding to all the advanced threats targeting your endpoints. Keep your business running. Compromised endpoints are highly disruptive to business. Innovative attack prevention and attack surface reduction delivers the strongest security across the entire attack life cycle (e.g., stealthy malware, credential theft, fileless, and “living off the land” attacks). Prevent the worst-case scenario. Full blown breaches are CISOs' worst nightmare. Deliver detection and remediation of persistent threats with sophisticated attack analytics and prevention of AD credential theft.
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    ESET PROTECT
    Protect your company endpoints, business data and users with ESET's multilayered technology. ESET PROTECT platform offers customizable security solutions, easy to manage from a cloud console. Cyber risk management and visibility into your IT environment. Stay one step ahead of any known or unknown threats. Up-to-date information and customized notifications allow the IT staff to react promptly to any risks that may have developed. Smart predefined policies and automated tasks help IT admins save time and better protect against future attacks. Easily meet reporting requirements and save time with scheduled reporting and dozens of customizable templates. A user within your network might open a malicious email containing a new form of ransomware. Programmers who work with code on their work computers might tend to create false positives due to compiling software.
    Starting Price: $239 per year
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    ESET PROTECT Complete
    ESET PROTECT Complete is a comprehensive cybersecurity solution designed to safeguard business endpoints, cloud applications, and email systems. It offers advanced protection against ransomware and zero-day threats through cloud-based sandboxing technology and machine learning-driven detection. It includes full disk encryption capabilities, aiding compliance with data protection regulations. ESET PROTECT Complete also provides robust security for mobile devices, file servers, and email servers, incorporating anti-malware, anti-phishing, and anti-spam measures. Its centralized, cloud-based management console allows for streamlined deployment, monitoring, and response to security incidents across the organization. Additional features include vulnerability and patch management, ensuring that software vulnerabilities are promptly identified and addressed.
    Starting Price: $287.72 one-time payment
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    ESET PROTECT Elite
    ESET PROTECT Elite is an enterprise-grade cybersecurity solution that integrates extended detection and response with comprehensive multilayered protection. It offers advanced threat defense using adaptive scanning, machine learning, cloud sandboxing, and behavioral analysis to prevent zero-day threats and ransomware. The platform includes modern endpoint protection for computers and smartphones, server security for real-time data protection, and mobile threat defense. It also features full disk encryption, helping organizations comply with data protection regulations. ESET PROTECT Elite provides robust email security, including anti-phishing, anti-malware, and anti-spam technologies, along with cloud app protection for Microsoft 365 and Google Workspace. Vulnerability and patch management capabilities allow for automatic tracking and patching of vulnerabilities across all endpoints.
    Starting Price: $275 one-time payment
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    Microsoft Defender for Endpoint
    Gain the upper hand against sophisticated threats like ransomware and nation-state attacks. Put time back in the hands of defenders to prioritize risks and elevate your security posture. Advance beyond endpoint silos and mature your security based on a foundation for XDR and Zero Trust. Microsoft Defender for Endpoint delivers industry-leading endpoint security for Windows, macOS, Linux, Android, iOS, and network devices and helps to rapidly stop attacks, scale your security resources, and evolve your defenses. It’s delivered at cloud scale, with built-in AI that reasons over the industry’s broadest threat intelligence. Our comprehensive solution enables discovery of all endpoints and even network devices, such as routers, in your environment. It offers vulnerability management, endpoint protection, endpoint detection and response (EDR), mobile threat defense, and managed hunting all in a single, unified platform.
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    Juniper Advanced Threat Protection
    Juniper Advanced Threat Prevention (ATP) is the threat intelligence hub for your network. It contains a litany of built-in advanced security services that use the power of AI and machine learning to detect attacks early and optimize policy enforcement networkwide. Juniper ATP runs as a cloud-enabled service on an SRX Series Firewall or as a virtual appliance deployed locally. It finds and blocks commodity and zero-day malware within files, IP traffic, and DNS requests. The service assesses risk from encrypted and decrypted network traffic and connected devices, including IoT devices, and distributes that intelligence throughout the network, drastically decreasing your attack surface and helping avoid breaches. Automatically discover and mitigate known and zero-day threats. Identify and stop threats hiding within encrypted traffic without decrypting. Detect targeted attacks on your network, including high-risk users and devices, and automatically mobilize your defenses.
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    Sophos Intercept X Endpoint
    Take threat hunting and IT security operations to the next level with powerful querying and remote response capabilities. Ransomware file protection, automatic file recovery, and behavioral analysis to stop ransomware and boot record attacks. Deep Learning Technology Artificial intelligence built into Intercept X that detects both known and unknown malware without relying on signatures. Deny attackers by blocking the exploits and techniques used to distribute malware, steal credentials, and escape detection. Elite team of threat hunters and response experts who take targeted actions on your behalf to neutralize even the most sophisticated threats. Active adversary mitigation prevents persistence on machines, credential theft protection, and malicious traffic detection.
    Starting Price: $28 per user per year
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    iPrism Web Security
    iPrism Web Security offers a unique combination of fine-grained content filtering combined with threat detection and mitigation methods to assure powerful protection from Advanced Persistent Threats, including botnets, malware, viruses and others. iPrism Web Security is designed to be “set it and forget it” easy to use, self-contained to provide advanced threat protection and policy enforcement, yet require nearly zero maintenance. And our comprehensive on-box reporting makes managing your network a snap. iPrism uses our unique combination of iGuard automated intelligence and expert human analysis to block things like malware, Crypto-Locker and inappropriate sites. It also provides improved user productivity with low latency and false positive rates. This innovative approach ensures you have the most updated, advanced web protection 24/7 that is backed by world-class customer support.
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    SandBlast Network

    SandBlast Network

    Check Point Software Technologies

    As cyber attacks become increasingly evasive, more controls are added, making security more complicated and tedious to the point that user workflows are affected. SandBlast Network provides the best zero-day protection while reducing security overhead and ensuring business productivity. SandBlast Network provides the best zero-day protection in the industry, while reducing administration overhead and ensuring ongoing business productivity. Powerful threat intelligence and AI technologies prevent unknown cyber threats. Single click setup, with out-of-the-box profiles optimized for business needs. Delivering a prevention-first strategy with no impact on user experience. Humans are the weakest link in the security chain. Pre-emptive user protections eliminate threats before they reach the users regardless of the user activity – browsing or using email. Real-time threat intelligence derived from hundreds of millions of sensors worldwide.
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    FortiSandbox
    Unlike previous generation of viruses that were non-sophisticated and low in volume, antivirus tools were sufficient to provide reasonable protection with their database of signatures. However, today’s modern malware entails new techniques such as use of exploits. Exploiting a vulnerability in a legitimate application can cause anomalous behavior and it’s this behavior that attackers take advantage of to compromise computer systems. The process of an attack by exploiting an unknown software vulnerability is what is known as a zero-day attack aka 0-day attack, and before sandboxing there was no effective means to stop it. A malware sandbox, within the computer security context, is a system that confines the actions of an application, such as opening a Word document, to an isolated environment. Within this safe environment the sandbox analyzes the dynamic behavior of an object and its various application interactions in a pseudo-user environment and uncovers any malicious intent.
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