Best Manufacturing Software in the USA
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Compare the Top Manufacturing Software in the USA as of October 2025
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What is Manufacturing Software in the USA?
Manufacturing software is a type of software that is designed to improve the efficiency and accuracy of production and manufacturing processes. It can be used to automate various stages of production, such as inventory optimization, order tracking, work scheduling and quality assurance. It also offers features for analyzing data related to production operations, helping companies identify areas for improvement and cost-effectiveness. Manufacturing software helps streamline the manufacturing process, promoting higher productivity with less manual labor. Compare and read user reviews of the best Manufacturing software in the USA currently available using the table below. This list is updated regularly.
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1
Quickbase
Quickbase
Deliver workflows and real-time visibility across your operations so your teams can outpace change. Extend and connect data, processes, and workflows to drive deeper insight and automation across complex processes and disparate systems. Adapt your operations faster to respond to opportunities and risks. Tailor workflows to support the unique, ever-changing ways your people work. Create new workflows to respond to emerging challenges and support new ways of working in days, not weeks. Create, connect, govern and continually improve an ecosystem of custom digital solutions on a secure platform for your most critical data and processes. Transform the way your data is used and safely empower your people to deliver real-time insights from one unified platform. Unlock your team's potential. Get started with Quickbase today.Starting Price: $600 per month -
2
Intelex
Intelex Technologies
Intelex is an integrated software solution for managing Environmental, Health, Safety and Quality (EHSQ) programs. Intelex’s scalable platform is designed to store, manage and analyze EHS and Quality data in one place. The solution works on any device to meet the realities of your workplace. With Intelex, your organization can: - Drive better results in your EHSQ program by monitoring workflows to achieve top performance and gain control. - Identify trends and tendencies by setting goals to gain greater insight into your EHSQ program to enhance judgement. - Reduce incidents and administrative work by easily monitoring, managing, optimizing and drawing insights from your safety data with our user-friendly safety software solution. - Streamline air, water and waste emissions management and reporting, and track and manage environmental outputs to achieve sustainability goals. - Drive continuous quality improvement activities across multiple departments, sites or locations. -
3
eBuyerAssist
Eyvo eProcurement
eBuyerAssist by Eyvo is a comprehensive, cloud-based eProcurement solution built to serve organizations of all sizes and industries. Fully modular and scalable, it simplifies and automates the entire procurement lifecycle—from requisition to fulfillment. The platform features advanced tools for: 1. Strategic sourcing 2. Supplier and contract management 3. Inventory and warehouse operations 4. Approval workflows and purchase orders 5. Budget control and cost accounting 6. Invoice matching and vendor credit checks 7. Risk analysis and compliance tracking eBuyerAssist centralizes procurement into a single, intuitive system—enhancing visibility, improving control, and driving efficiency across the organization. Whether your goal is cost reduction, improved compliance, or aligning procurement with broader strategic objectives, eBuyerAssist delivers faster, smarter results with measurable ROI.Starting Price: $39.00/month/user -
4
Total Lean Management (TLM) Software
Lean & Mean Business Systems
Perfect for a small company, TLM has everything you need, and can accelerate the implementation with consulting, training, procedure templates, and document writing/coaching support, plus we have validation templates and a system setting mode so small medical device companies have special features to help manage technical files and 510K submittals. TLM QMS Software saves you money AND makes your QMS more effective by providing a dual technology landscape for the two distinct QMS user types. Core modules include: • Audits • Contact Manager (CRM) • CAPA • Customer Feedback • Document Management • Electronic Forms • Employees • Employee Feedback • Equipment Calibration • Evaluations • FMEA • Inspections • Inventory/parts • Library • Meetings/Reviews • Metrics • Projects • Purchase Orders • Quality Record Mgt • Rejected Materials • Risk & Opportunities • Sales Orders • Strategic Planning • Surveys • Tasks/Events • Training • Work OrdersStarting Price: $45/user/month -
5
Artintech ERP
Artintech
Artintech ERP is a comprehensive enterprise resource planning solution designed to optimize and streamline your business operations across various departments. Tailored for small to medium-sized enterprises (SMEs), Artintech ERP offers robust functionality with a user-friendly interface, allowing businesses to seamlessly manage their resources, inventory, human capital, finances, and customer relations all in one integrated platform. Artintech ERP includes a wide range of modules designed to optimize business operations. Key modules include Procurement, Warehousing, CRM, Distribution, Quality Management (QMS), Workplace Safety, Document Control, Non-Conformance and Corrective and Preventive Actions (CAPA), Inspection, and Computerized Maintenance Management System (CMMS).Starting Price: $24.95/Module/Month -
6
Qualityze EQMS Suite
Qualityze
Qualityze is a leading provider of enterprise quality management solutions, utilizing the Salesforce.com Technology Platform to build our EQMS Software solutions. Our team is 100% devoted to quality processes, compliance, and regulatory guidelines to address our customers' business environments. We do not distract ourselves with custom work or quality concerns. The idea of helping our customers create a culture of quality is not a new concept, but the way we developed our application, Quality Management Software, based on making it easy to use, intuitive, and inclusive. Therefore, the entire organization is involved in quality, not because they are told they should, but because it's easy, fun, and has a logical flow. We strive to optimize quality with excellence through our exclusive range of smarter quality management software solutions.Starting Price: $30/User/Month -
7
nTask
nTask
nTask is an online project management platform, known for pioneering simplified work management. The platform helps to get more done while meeting all of the quality standards of industries. nTask is extensively customizable, and one of the most affordable in the industry. nTask is designed for all-sized teams and industries. Over 200,000+ companies trust nTask globally for managing campaigns, sprints, product development, inventory, clients, company goals & targets, and much more. nTask enables faster project completion through one platform that enables all team members to work efficiently without shuffling through multiple apps and has all the tools necessary for project management, such as custom fields, financial summary, task management, risk management, issue tracking, Gantt charts, Kanban boards, team collaboration, documents sharing, to-do lists, project planning, resource allocation, time tracking, timesheets module, roles/permissions, and workspace customizationsStarting Price: $3 per user/month -
8
Kohezion
TGMT-Systems
Kohezion is a low code online database builder that empowers users to create their own software solutions in a fraction of the time. Kohezion supports your organization's high-security requirements by prioritizing accountability, encryption, and compliance for storing confidential data. Build database applications that can be customized to meet your exact needs right now, and as you experience growth and change. Collaborate, innovate, and build a system where your data works for you.Starting Price: $25/month -
9
SimplerQMS
SimplerQMS
SimplerQMS offers a cloud-based Quality Management Software that is fully validated according to GAMP5 and specifically designed for the Life Science industry. This comprehensive QMS platform helps ensure compliance with various regulatory requirements, including FDA 21 CFR Part 11, EU Annex 11, GxP, cGMP, GAMP 5, GDPR, EU IVDR & EU MDR, ISO 13485:2016, 21 CFR Part 820, ICH Q10, and others. The software offers a wide range of Life Science QMS modules, such as Document Control, Change Management, Training Management, Supplier Management, Complaints Management, Non-Conformance and Deviation Management, CAPA Management, Audit Management, Technical Documentation Management, Risk Management, Quality KPIs, among others, ensuring a seamless experience. SimplerQMS enhances document handling by allowing users to work directly in Microsoft Office applications like Word, PowerPoint, and Excel.Starting Price: $13,750/year -
10
Sunday Business Systems
Sunday Business Systems
Sunday Business Systems (SBS) offers comprehensive quality management software (QMS) and consulting services to improve compliance with quality management standards, including ISO 9001, AS9100, ISO 14001, ISO 45001, and ISO 13485. Our solutions, such as Corrective Action and Preventive Action (CAPA) management, document control, and employee training management, help businesses streamline operations while ensuring compliance with industry regulations. SBS provides software tools for a full rangce of systems including audit management, calibration control, Preventive maintenance, EHS tracking, vendor management and inspection data collection and statistical process control (SPC). SBS provides on-premise and cloud-based solutions and customized software tailored to the unique needs of small businesses, improving productivity and operational efficiency. SBS offers the best value in QMS software.Starting Price: $295 -
11
Xybion LIMS
Xybion
Xybion LIMS (formerly Labwise XD) is an all-inclusive LIMS, ELN, QMS, and DMS. Xybion LIMS drives lab workflows, instills consistency, improves data quality, and supports regulatory compliance with a complete laboratory management solution that connects with your operating systems with powerful laboratory information management and analytics. Xybion LIMS creates optimized workflows for the unique business needs of all regulated laboratories including research, diagnostics, quality control, stability studies, and more. -
12
Sinnaps
Sinnaps
Sinnaps is the first intelligent project manager; easy to use, it can simplify complex projects and plan your team work automatically based on your needs. Its exclusive technology employs a powerful rendering engine based on PERT (Project Evaluation and Review Techniques) and CPM (Critical Path Method) algorithms which help optimise project management and provide guidance for the decision-making process. Featured Sinnaps services: interactive planning; risk prediction and management; resource optimisation; and expectation management.Starting Price: $9 -
13
Tulip
Tulip
Tulip's flexible, no-code frontline operations platform helps manufacturers create front-end applications that guide operators, collect data from workers, machines, and devices, and track metrics against your KPIs. With Tulip, companies can digitally transform their operations in days, gaining real-time visibility of their operations to increase productivity, reduce errors, and drive continuous improvement.Starting Price: $1,200 per year -
14
EQMS
Qualsys
Embed quality throughout your business with an integrated Electronic Quality Management System (EQMS) from Qualsys. Flexible and intuitive, Qualsys' EQMS solution helps create happier and healthier businesses by providing a combination of modules that are effective for making quality a responsibility of every employee within an organization. Top modules include Document Manager, Training Manager, Risk Manager, Asset Manager, Supplier Manager, and many more.Starting Price: $50.00/month/user -
15
Armis
Armis Security
Armis, the leading asset visibility and security company, provides the industry’s first unified asset intelligence platform designed to address the new extended attack surface that connected assets create. Fortune 100 companies trust our real-time and continuous protection to see with full context all managed, unmanaged assets across IT, cloud, IoT devices, medical devices (IoMT), operational technology (OT), industrial control systems (ICS), and 5G. Armis provides passive cyber asset management, risk management, and automated enforcement. Armis is a privately held company and headquartered in California. -
16
EZ-GO Platform
EZ Factory
EZ Factory is a SAAS Company with a software solution called “the EZ-GO platform”. This is a mobile solution, with a focus on continuous improvement within production environments. The simple and visual software platform is used in factories to digitize checklists, work instructions, first-line maintenance tasks, and audits to improve safety, quality, training and efficiency on the shop floor. Front-line factory workers finally know what to do, why, where, when, and how to do it. Improve safety, quality and efficiency by digitizing paper forms, lists and other documents on the shop floor. The EZ-GO platform is a mobile solution, with a focus on continuous improvement within production environments. The simple and visual app is used in factories to digitize checklists, first line maintenance tasks and audits. Furthermore, the solution offers the possibility to setup work instructions and motivates operators to propose improvements. -
17
Qualio
Qualio
Qualio is an all-in-one quality and compliance management platform built for small and growing businesses in life sciences and healthcare. Reliable, affordable, and easy to use, Qualio helps companies building life saving products get to market faster by reaching 100% ISO, GxP, and FDA compliance. With Qualio, companies can conveniently manage document control, training, CAPAs, NCRs, audits, suppliers, complaints, and more in one platform. -
18
EASE
Ease Inc.
EASE is the innovative audit and insights platform used by leading manufacturers to conduct layered process audits, safety audits, 5S and more. EASE brings visibility and accountability to the plant floor through real-time actionable data and streamlines how manufacturers administer, conduct and respond to plant floor audits. Forget paper and pencils. The EASE mobile app guides your audits including responses to non-conformances and annotated photos that provide visual evidence. With Issue tracking, assign issues to appropriate parties and ensure they’re closed out. Interactive dashboards and customizable reports provide real-time audit results and insights by line, plant, region or business unit. -
19
Radley Traceability
Radley Corporation
Are you prepared for recalls or audits? Get real-time access to full bi-directional traceability! Radley Traceability is a complete track and trace software solution for the manufacturing industry. Enjoy full visibility throughout your supply chain. Powered by Radley's trademarked IntelliLabel technology, Radley’s Traceability Software lets you easily collect, store, and trace data forward and/or backward in the supply chain. Core functionalities include chain of custody, product pedigree management, configurable workflows, multiple data capture options, co-mingled lot tracking, individual part and direct part marking, serialized containers, and so much more. Supports GS1 standards for scanning & labeling. Can also be used as a stand-alone solution or integrated to your ERP/back-end system. Capture unlimited properties: lot, supplier, expiration, sample/quality, weight and transit time. -
20
Deltek Costpoint
Deltek Costpoint
Increase profitability and improve project success for government contractors with Costpoint Manufacturing by bringing efficiency and digitalization to the operations process—from bid to shipment. Tie all data to financials in one secure system; paper processes are digitalized as data is captured, stored and analyzed in real-time, down to the project level. Consistently collect and allocate costs and simplify adherence to contract requirements by including traceability and contract flow downs. Withstand interruptions with modernized, flexible and integrated automation for visibility into changes and process control. Connect and automate processes between finance and production for improved accuracy, true costs and audit readiness. Leverage contract flow downs and organizational, project and part security. And automate traceability on every transaction. -
21
SAP S/4HANA
SAP
SAP S/4HANA Intelligent ERP system for today’s business. Discover a truly modern ERP system with embedded AI and machine learning – available on premise, in a public or private cloud, or in a hybrid environment. SAP S/4HANA is a future-ready enterprise resource planning (ERP) system with built-in intelligent technologies, including AI, machine learning, and advanced analytics. It transforms business processes with intelligent automation and runs on SAP HANA – a market-leading in-memory database that offers real-time processing speeds and a dramatically simplified data model. Choose and deploy from a wide range of SAP S/4HANA ERP capabilities – all of which leverage the latest technologies and intelligent automation to transform your business processes. Capabilities span lines of business, from finance, supply chain, and manufacturing to sales, distribution, and more. -
22
CAQ.Net
CAQ AG Factory Systems
CAQ AG Factory Systems has established itself as one of the worldwide leading providers of quality management software. We have over 30 years of experience in the development and distribution of modular, multilingual, and industry-specific management solutions for small and medium-sized enterprises as well as multinational corporations. Our CAQ.Net software suite covers every aspect of computer aided quality assurance and was designed with the highest degrees of adaptability and customizability in mind. Just like a construction kit, our system allows you to pick the most suitable building blocks and thereby create the perfect solution to your individual quality management demands. Why CAQ.Net? Updates, Upgrades & Release Changes Support from QM & IT Professionals User Workshops Screencasts Conformity to Standards Information Security SaaS or On-Premises Floating Licenses Multitenancy Multilingual No-Code-Designer Validation Capability AI Assistants ... -
23
LiveSource
WiseTech Global
Blume Global’s solution for manufacturers (Livesource) is a purpose-built platform for managing the entire direct material lifecycle, from sourcing and supplier collaboration to quality management and inbound logistics execution. Designed for complex, global supply chains, Blume connects engineering, procurement, and logistics teams with suppliers on a unified, BOM-centric platform. With integrated APQP, PPAP, RFQ, ASN, and packaging workflows, manufacturers gain real-time control over part-level risk, supplier performance, and production readiness. The platform delivers insights powered by AI-ready data and provides true multimodal visibility across transportation modes. Blume’s modular platform integrates seamlessly with ERP and PLM systems, accelerates supplier onboarding, reduces order cycle time by up to 90%, and improves on-time delivery by 18% without the need to replace your existing systems. -
24
QAD EQMS
QAD
QAD EQMS, formerly CEBOS, is a fully integrated enterprise quality solution that provides timely visibility into manufacturing and quality related issues. It facilitates a preventative approach resulting in reduced cost of quality, improved manufacturing throughput, improved customer satisfaction and higher manufacturing margins. QAD EQMS addresses the breadth of the value chain of suppliers and internal manufacturing to optimize quality performance. -
25
AssurX
AssurX
The AssurX platform is a versatile enterprise quality management system (EQMS) and regulatory compliance management platform. AssurX allows enterprises of any size or complexity to create a system that reliably communicates and coordinates quality and compliance information, documentation, and activities across the enterprise. AssurX allows regulated businesses to quickly identify and control risk exposure and avoid quality or noncompliance problems while improving workflow. AssurX QMS software is highly configurable to fit any established or dynamic business requirements. The system creates an electronic workflow of tasks, alerts, escalations, and approvals that can be automated to the desired level, mapping precisely to real-world operations. Begin with just the solutions and functionality you need now, then implement what you like whenever you’re ready. No other system is easier to deploy, configure, and modify. -
26
Knowllence
Knowllence
Risk management integrator. Knowllence offers software and training and consulting services for truly effective QSE risk management. Manage the Safety of your employees (single document, arduousness, chemical risk). Manage your robust design process (functional analyzes, FMEA FMEA, FTA). Manage the robustness of your industrialization (AMDEC Process FMEA, monitoring plan). Control risks according to ISO 14971 and the design of your medical devices. We understand the methodologies that suit you and adapt, if necessary, the configuration of our software to precisely follow your standards and processes. We are able to provide you with a complete service to facilitate your work sessions and your risk studies, in order to move your project forward, while making the system sustainable: you keep control of the study and the plans of actions within efficient and easy-to-use software. -
27
GoHACCP
iQKitchen
GoHACCP compliance software is the simplest most cost effective way to organize your operations, so you never have to worry about missing or incomplete records again. A system that constantly monitors with smart alerts, and analyzes real threats before they become and issue. A self-auditing platform that continually directs relevant data to the right places. A gamified video based training platform that encourages learning and staff engagement. Working around the clock to guarantee safety and compliance. Customized systems, patented software and technology. Experience real-time metrics on all audit related records with our dashboard system. Improve your compliance score to pass any audit. Boost efficiency with your compliance data gathering and organisation. -
28
PLATO SCIO
PLATO AG
The PLATO software SCIO™ is especially popular with experts and moderators. The web-based software PLATO e1ns is recommended to ensure easy handling for all team members in the engineering department. It implies the most important SCIO™ functions. PLATO e1ns is the system for the optimal design of the product development process (PDP). With e1ns PLATO has developed a solution that works in the early stages of PDP. Right where you lay the foundation for cost and risk avoidance. Thanks to the database technology of SCIO™-FMEA, the requirements of knowledge management, multi-user capability and foreign language support are fulfilled. SCIO™-Matrix is the fast method of system analysis. It is used to convert customer requirements into product functionalities through optimal implementation. Complete planning and documentation of process steps. Securely stored and ready for retrieval in the SCIO™ database. -
29
EviView
EviView
EviView is a comprehensive digital daily management system designed to centralize and standardize frontline operations in batch manufacturing environments. The platform digitizes shift handovers, tiered meetings, audits, and continuous-improvement initiatives by connecting teams to real-time data and KPIs, replacing fragmented Excel trackers and paper logs. EviView adapts to existing processes and scales as needs evolve, while single-tenant VPC hosting and SSO-over-SAML ensure enterprise-grade security. Global leaders in pharmaceuticals, biopharma, chemical, food & beverage, energy, and other batch industries use EviView to reduce downtime, boost safety incident reporting, and drive continuous improvement. From browser-based dashboards to mobile access, the system transforms scattered data into actionable insights, aligns teams around a single source of truth, and empowers managers to make confident, data-driven decisions that elevate operational excellence. -
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Lyons Quality Audit Tracking LQATS
Lyons Information Systems
Lyons Quality Audit Tracking System (LQATS)® is a robust, flexible, web-based solution to gather, analyze and display quality audit results generated by staff and suppliers of a manufacturing organization. LQATS gathers real time audit information worldwide from: Suppliers (shipment audits) Company auditors (final audits) Distribution centers Manufacturing plants LQATS provides real-time entry, tracking, and analysis of quality audit data from Distribution Centers and Supplier plant locations. Features include: "Smart controls" to minimize user data entry and retrieval tasks Change History tracking Quick search of data using many different query parameters Real-time global performance monitor Fabric Inspections Six-sigma analysis Disposition log Data displayed in both tabular and graphical formats with output to Excel, PDF, format