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Aldazide

This document summarizes the drug Aldazide, which contains spironolactone and butizide. It is used to treat hypertension, edema, ascites, nephritic syndrome, and idiopathic edema. It works by increasing sodium and water excretion while preserving potassium. The recommended dosage is 2-4 tablets per day for hypertension and up to 8 tablets daily for edema, if needed. Special precautions should be taken for patients with liver or kidney issues. Potential side effects include gynecomastia, gastrointestinal issues, and changes in electrolyte levels. Nursing responsibilities include educating patients and monitoring intake/output, weight, blood pressure, and electrolyte and renal function levels.

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7K views2 pages

Aldazide

This document summarizes the drug Aldazide, which contains spironolactone and butizide. It is used to treat hypertension, edema, ascites, nephritic syndrome, and idiopathic edema. It works by increasing sodium and water excretion while preserving potassium. The recommended dosage is 2-4 tablets per day for hypertension and up to 8 tablets daily for edema, if needed. Special precautions should be taken for patients with liver or kidney issues. Potential side effects include gynecomastia, gastrointestinal issues, and changes in electrolyte levels. Nursing responsibilities include educating patients and monitoring intake/output, weight, blood pressure, and electrolyte and renal function levels.

Uploaded by

ianecunar
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd

Brand Name: Aldazide

Generic Name: Spironolactone 25 mg, Butizide 2.5 mg


Indications: Essential hypertension, edema and ascites of CHF, liver cirrhosis, nephritic
syndrome, idiopathic edema
Drug Classification: Diuretic
Mechanism of Action: : competes with aldosterone for receptor sites in the distal renal
tubules, increasing sodium chloride and water excretion while conserving
potassium and hydrogen ions, may block the effect of aldosterone on arteriolar
smooth muscle as well
Dosage: Essential Hypertension 2-4 tab/day for 2 weeks or longer. Edema initially 4 tab
daily then reduce to optimum dose. If adequate diuretic does not occur after 3
days, increase dose up to 8 tab daily. Children 1.65-3.3 mg of
spironolactone/kg/day in divided doses
Special Precautions: Acute or severe hepatic failure decompensated hepatic cirrhosis,
pregnancy, lactation, concominant administration of K supplements or other K
sparing agents, SLE. Monitor fluid and electrolytes.
Pregnancy Risk Category D
Adverse reaction: Gynecomastia, GI symptoms, lethargy, headache and
thrombocytopenia, leukopenia, agranulocytosis, cutaneous eruptions, pruritus,
mental confusion, paresthesia, acute pancreatitis, jaundice, orthostatic
hypertension, muscle spasm, weakness, fever, ataxia
Contraindications: Acute renal insufficiency, significant impairment of renal function,
anuria, hyperkalemia
Form: tab 100’s
Nursing Responsibilities:
 Educate patient to avoid hazardous activity such as driving until response to
drug is known.
 Take with meals or milk; avoid excessive ingestion of food high in potassium or
use of salt substitutes
 Diuretic effect may be delayed 2-3 days and maximum hypertensive may be
delayed 2-3weeks; monitor I and O ratios and daily weight, BP, serum
electrolytes (K, Na) and renal function

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