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Pain Pathway

1) The document describes the pain pathway in the human body. 2) Pain signals travel from nociceptors in the skin and tissues up the spinal cord and through several structures in the brainstem and limbic system. 3) The signals are processed at multiple levels to integrate the sensory, emotional, and cognitive aspects of the pain experience.

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Imroze Habib
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188 views1 page

Pain Pathway

1) The document describes the pain pathway in the human body. 2) Pain signals travel from nociceptors in the skin and tissues up the spinal cord and through several structures in the brainstem and limbic system. 3) The signals are processed at multiple levels to integrate the sensory, emotional, and cognitive aspects of the pain experience.

Uploaded by

Imroze Habib
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

Pain pathway

LIMBIC SYSTEM

3rd
SOMATOSENSORY Orde
CORTEX r
Neur
on
RETICULAR FORMULATION
BRAIN STEM THALAMUS OR
PERI-AQUEDUCTAL GREY
2nd
Orde
SPINOTHALAMIC
r
SPINORETICULAR SPINOMESENCEPHALIC
TRACT TRACT TRACT Neur
on

ASCENDS SEVERAL SEGMENTS IN THE SPINAL CORD BEFORE


CROSSING OVER TO THE OPPOSITE VENTROLATERAL SIDE

LAMINA
V Zone of Convergence

LAMINA LAMINA Dorsal Horn of


III, IV I, II Spinal Cord
1st
Dorsal Root Orde
LARGE DIAMETER CELLS SMALL DIAMETER CELLS
Ganglia r
Neur
Aβ Aδ C Afferent Neurons on
VANILLOID ACID SECRETING PURINERGIC
RECEPTOR ION CHANNEL RECEPTOR
(VR1) RECEPTOR Nociceptors
(ASIC)

TOUCH AND HEAT H+ ATP


PROPRIOCEPTION
PAINFUL STIMULUS

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