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Nuclear Medicine: Diagnosis & Therapy

Nuclear medicine utilizes gamma rays from radionuclides and pharmaceutical compounds to image disease processes earlier and ablate diseased tissue through beta particles. It involves the use of radiotracers, gamma cameras, and computers to produce images of organs and whole body scans. Examples of nuclear medicine imaging include brain, heart, lung, and thyroid scans, while therapies include using iodine-131 for hyperthyroidism and thyroid cancer or yttrium-90 for lymphoma.

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Parvez Ahmed
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38 views5 pages

Nuclear Medicine: Diagnosis & Therapy

Nuclear medicine utilizes gamma rays from radionuclides and pharmaceutical compounds to image disease processes earlier and ablate diseased tissue through beta particles. It involves the use of radiotracers, gamma cameras, and computers to produce images of organs and whole body scans. Examples of nuclear medicine imaging include brain, heart, lung, and thyroid scans, while therapies include using iodine-131 for hyperthyroidism and thyroid cancer or yttrium-90 for lymphoma.

Uploaded by

Parvez Ahmed
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PPT, PDF, TXT or read online on Scribd

Role of Nuclear Medicine in Diagnostic & Therapeutic Aspect

Dr. Parvez Ahmed Center for Nuclear Medicine & Ultrasound, Rajshahi, Bangladesh 25/01/2011

Role of Nuclear Medicine/Molecular medicine/ Molecular imaging & therapeutics


Safest, painless & cost-effective branch of medicine and medical imaging. utilize gamma ray from radionuclides with or without pharmaceutical compounds image disease process at an earlier stage, based on physiology Ablate diseased tissue by beta particle.

John H. Lawrence first use P32 to treat leukemia in 1936

Role of Nuclear Medicine/Molecular medicine/ Molecular imaging & therapeutics


3 Core Components in NM imaging: Radionuclides (relatively short-lived) Gamma camera (used in scintigraphy, SPECT & PET) Computer (Software) Examples of NM Imaging: Organ specific like Brain, Heart, Lung, Liver, Thyroid, Parathyroid etc. Whole body imaging, based on cellular receptors, like whole body PET or PET/CT scan, gallium scan, indium scan, MIBG and octreotide/somatostatin receptor scan.

David E. Kuhl invented the concept of emission & transmission tomography in 1962 which led to design of SPECT,PET, CT & their fusions.

Role of Nuclear Medicine/Molecular medicine/ Molecular imaging & therapeutics


Examples of NM therapy: 131I for hyperthyroidism and thyroid cancer, Yttrium-90(Zevalin) and Iodine131(Bexxar) for refractory Lymphoma, 131I-MIBG for neuroendocrine tumors, Palliative bone pain treatment with Samarium-153 or Strontium-89, Implanted capsules of isotopes (brachytherapy) to treat cancer.

Upper L-PET, Upper R-PET/MRI, Lower-PET/CT (1996) (2008) (2008)

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