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Cartilage, Bone, Muscle

The document summarizes the microscopic structures of cartilage, bone, and muscle tissue. It describes the main cells and extracellular matrix components of cartilage, including chondrocytes in lacunae and ground substance containing proteoglycans. It also outlines the three types of cartilage: hyaline, elastic, and fibrous. For bone tissue, it identifies the main cells as osteoprogenitor cells, osteoblasts, osteocytes, and osteoclasts. It describes the bone matrix containing collagen fibers and hydroxyapatite. Key structures of compact bone are highlighted like osteons, Haversian systems, and lamellae. Muscle tissue is classified as skeletal, cardiac, and smooth muscle with an overview of

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90 views43 pages

Cartilage, Bone, Muscle

The document summarizes the microscopic structures of cartilage, bone, and muscle tissue. It describes the main cells and extracellular matrix components of cartilage, including chondrocytes in lacunae and ground substance containing proteoglycans. It also outlines the three types of cartilage: hyaline, elastic, and fibrous. For bone tissue, it identifies the main cells as osteoprogenitor cells, osteoblasts, osteocytes, and osteoclasts. It describes the bone matrix containing collagen fibers and hydroxyapatite. Key structures of compact bone are highlighted like osteons, Haversian systems, and lamellae. Muscle tissue is classified as skeletal, cardiac, and smooth muscle with an overview of

Uploaded by

anggitaaa
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Microscopic structure of cartilage, bone and muscle.

(textus cartilagineus,textus osseus and textus muscularis)


Ghufron Dept. of Histology and Cell Biology School of Medicine UGM

CARTILAGE

Cartilage Tissue
cells called chondrocytes gel-like ground substance containing proteoglycans and glycosaminoglycans. elastic, inelastic, or reticular fibers.

Matriks Cartilago

Basic histology 11th ed

HYALINE CARTILAGE ELASTIC CARTILAGE FIBROCARTILAGE

HYALINE CARTILAGE
HISTOGENESIS HYALIN CARTILAGE

mesenchyme

highly cellular tissue

chondroblas separated

multiplication of C isogenous group

LACUNA HYALINE CARTILAGE articular cartilage costal cartilage, trachea larynx CHONDROCYTE

PERICHONDRIUM

GROUND SUBSTANCE

HYALINE CARTILAGE

PERICHONDRIUM

CHONDROCYTE

stratum chondrogenicum PERICHONDRIUM stratum fibrosum

Elastic cartilage elastin fibers in the matrix

CHONDROBLAST

CHONDROCYTES

ELASTIN

*AURICULA *EPIGLOTTIS

ELASTIC CARTILAGE

FIBROCARTILAGE

LACUNA

COLLAGEN FIBERS

CHONDROCYTES

aligned cells with bundles of collagen

Cartilage Located in the Human Skeleton

BONE TISSUE

* CELLS (OSTEOCYTES) * MATRIX

Cells in bone:
*Osteoprogenitor cells differentiate into Osteoblasts. *Osteoblasts synthesise new matrix Osteogenesis *Osteocytes = mature bone cells In lacunae Connected by canaliculi *Osteoclasts dissolve bone matrix Osteolysis

Cells Associated with Bone Tissue

osteoprogenitor cells: derived from mesenchyme these differentiate into osteoblasts. osteoblasts: bone forming cells which secrete the osteoid and then calcify it. osteoclasts: bone resorbing cells derived from monocytes.

The Histology of Compact Bone

osteoclast resorption bone remodelling in response to growth; participate in the long-term maintenance of blood calcium homeostasis

MATRIX :
collagen fibers (type I) proteoglycans (glycoproteins) Hydroxyapatite: inorganic salt of calcium and phosphorus

Basic histology 11th ed Basic histology 11th ed

HAVERSIAN SYSTEM

Basic histology 11th ed

An Osteon

canaliculi.

The Haversian Canal

The Haversian Canal


( longitudinal)

Osteons Produce the Dense Arrangement in Ground Bone Tissue

Interstitial lamellae

Concentric lamellae.

? ? ?

Compact bone and spongy bone


Basic unit of compact bone is an osteon Osteocytes arranged around a central canal Perforating canals extend between adjacent osteons Spongy bone contains trabeculae

PERIOSTEUM

DEVELOPING BONE

O:OSTEOBLAST C:COLLAGEN ACTIVE PERIOSTEUM FROM DEVELOPING BONE

MUSCULAR INSERTION INTO BONE

EXTEND DEEPLY INTO THE BONY CORTEX

BONE HISTOENESIS * INTRAMEMBRANOSA * ENDOCHONDRAL

MUSCLE
TEXTUS MUSCULSRIS NON STRIATUS TEXTUS MUSCULARIS STRIATUS TEXTUS MUSCULARIS CARDIACUS

Basic histology 11th ed

SKELETAL MUSCLE

Endomysium Perimysium Epimysium

Tendon Deep Fascia Skeletal Muscle Muscle Fiber Fascicle art, vein, nerve

Connective Tissue Wrappings

Basic histology 11th ed

Basic hisyology 11th ed

Z SARCOMER Z

*MYOFIBRA *SARCOLEMMA (MP) *MYOFIBRIL *T TUBULUS *RETICULUM SARCOPLASMICUM (RE)

TRIAD : 1) T TUBULUS 2) SR OF I BAND 3) SR OF A BAND

JUNCTION OF THE A AND I BANDS T SYSTEM /TUBULUS TRIAD NEAR THE JUNCTION OF THE I AND A BANDS

A band

Z I band

A band

Ca2+ +TnC exposes the myosin binding site on actin (cross-hatched area) myosin head binds to actin ATP breaks down into ADB

CONTRACTION

MOTOR END PLATE

contraction begins whit the release of acetylcholine from the synaptic vesicles

(Basic histology 11th ed)

1) Basic Histology 11th ed Junqueira et al., 2010. 2) Wheather`s Functional HISTOLOGY 2008

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