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Insulin NPH

1. Insulin (Humulin) is an antidiabetic hormone given subcutaneously to manage diabetes mellitus by lowering blood glucose levels. 2. It works by stimulating glucose uptake in muscle and fat and inhibiting hepatic glucose production. 3. Side effects include hypoglycemia, lipodystrophy, rashes, and decreases in serum phosphate, magnesium, and potassium levels. Nurses monitor for hypoglycemia and hyperglycemia and interactions with many other drugs can impact insulin requirements.

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Christopher Lee
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1K views1 page

Insulin NPH

1. Insulin (Humulin) is an antidiabetic hormone given subcutaneously to manage diabetes mellitus by lowering blood glucose levels. 2. It works by stimulating glucose uptake in muscle and fat and inhibiting hepatic glucose production. 3. Side effects include hypoglycemia, lipodystrophy, rashes, and decreases in serum phosphate, magnesium, and potassium levels. Nurses monitor for hypoglycemia and hyperglycemia and interactions with many other drugs can impact insulin requirements.

Uploaded by

Christopher Lee
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd

Generic name Trade name Classification Route Time/Frequency Normal Dosage- 0.5-1 unit.

Given on
Insulin Humulin antidiabetics SubQ ACHS QID a scale BS- 150/50x2 = insulin given
NPH NPH hormones PRN w/ Accucheck
Indications- Management of diabetes mellitus Contraindications/warnings/interactions- Allergy to preservatives
or other additives. Use cautiously in: stress, pregnancy, and infection
(may temporarily increase insulin requirements)

Mechanism of action- Lower blood glucose by Common side effects- Hypoglycemia, lipodystrophy, pruritus, rash,
stimulating glucose uptake in skeletal muscle and fat,
inhibiting hepatic glucose production.

Lab value alterations- Decrease serum and inorganic phosphate,


magnesium and potassium levels.

Nursing Considerations- Take vitals; symptoms of hypoglycemia and


hyperglycemia. Monitor body weight periodically
Interactions with other patient drugs, OTC, or herbal
medicines- Beta blockers; Thiazide diuretics;
corticosteroids; acetazolamide; morphine; diltiazem; Why would you hold or not give Evaluation- Control of blood
dobutamine; thyroid preparations; estrogens; nicotine; this med? Hypoglycemia glucose levels without the
pretease inhibitor antiretrovirals; alcohol (chronic use); appearance of hypoglycemic or
rifampin; anabolic steroids (testosterone); clofibrate; hyperglycemic episodes
MAOIs; NSAIDS; oral hypoglycemic agents;
sulfinpyrazone; tetracyclines; phenylbutazone; ACE
inhibitors; sulfonamides; warfarin; Glucosamine;
Fenugreek; chronium; coenayme Q-10.

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