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Carpal tunnel syndrome
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Pathophysiology
The carpal tunnel is a narrow passage found at the base of the wrist hand and it contains tendons
and median nerve. The syndrome occurs mainly when the median nerve is compressed. The
nerve runs from the forearm through the carpal tunnel into the hand. The nerve controls
sensations that are experienced on the palm side of fingers and the thumb as well as impulse
coordination to muscles of the hand thus allowing movement of fingers and the thumb (Aboonq,
2015).
The tunnel syndrome occurs as a result of various factors that lead to pressure increase on the
median nerve and tendons passing through the tunnel. This disorder is caused by several factors
including congenital predisposition since it is smaller in some individuals that others. Other
factors that contribute to the condition include trauma that leads to swelling, sprain, fracture,
endocrine over activity, mechanical issues with the wrist joints, and development of a cancerous
cell such as cyst or tumor in the tunnel (Schnetzler, 2008).
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The result of the condition may lead to weakness, pain or numbness of the affected wrist and
hand radiating up to the arm. Despite the fact that painful sensation may indicate other
conditions, the syndrome is the most common associated with entrapment neuropathies where
the bodys peripheral nerves are traumatized and compressed.
The condition only occurs in adults. The first part to be affected is the dominant hand and
produces severe pain. Persons with metabolic disorders such as diabetes affects the nerves
directly making them susceptible to compression are at risk of developing the condition.
Etiology
Causes of carpal tunnel syndrome include inflammatory causes such as rheumatoid arthritis &
wrist arthritis, post-traumatic causes such as bone thickening after a colles fracture, endocrine
causes such as acromegaly & myxoedema and idiopathic causes which is the main cause of the
syndrome (Kim et al., 2014).
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References
Aboonq, M. S. (2015) Pathophysiology of carpal tunnel syndrome., Neurosciences (Riyadh,
Saudi Arabia), 20(1), pp. 49.
Kim, P.-T. et al. (2014) Current Approaches for Carpal Tunnel Syndrome, Clinics in
Orthopedic Surgery, 6(3), p. 253. doi: 10.4055/cios.2014.6.3.253.
Schnetzler, K. a. (2008) Acute Carpal Tunnel Syndrome, Journal of the American Academy of
Orthopaedic Surgeons, 16, pp. 276282. doi: 10.1001/jama.1963.03710040183054.