1. A client is diagnosed with type 1 DM.

The nurse understands that which of the following factors

is not believed to be a cause of the beta cell destruction that accompanies this disorder?
a. Genetic factors
b. Autoimmune factors
c. Primary failure of glucagon secretion
d. Viruses
2. A client with diabetes mellitus is prone to breaking down fats for conversion to glucose. The
nurse determines that this response currently is occurring if the client has elevated levels of
which of the following substances?
a. Glucose
b. Ketones
c. Glucagon
d. Lactic dehydrogenase
3. A client with diabetes mellitus who refuses to take insulin as prescribed has greatly increased
blood glucose levels following a meal. The nurse understands that which of the following initial
body responses to elevated glucose levels will worsen the situation for the client?
a. Glycogenolysis
b. Gluconeogenesis
c. Binding of glucose onto cell membranes
d. Transport of glucose across cell membranes
4. A client is experiencing an episode of hypoglycemia. The nurse understands that the
physiological mechanism that should take place to combat this decline in the blood glucose level
is
a. Decreased epinephrine release
b. Decreased cortisol release
c. Increased insulin secretion
d. Increased glucagon secretion
5. A client is diagnosed with Cushing’s syndrome. The nurse understands that this client has
excesses of which of the following substances?
a. Calcium
b. Cortisol
c. Epinephrine
d. Norepinephrine
6. A client has been diagnosed with pheocromocytoma. The nurse anticipates that the client will
exhibit which of the following effect based on the pathophysiology of this disorder?
a. Hypertension
b. Water loss
c. Decreased cardiac output
d. Bradycardia
7. A client has overactivity of the thyroid gland. The nurse anticipates that the client will
experience which of the following effects from this hormonal excess?
a. Low blood glucose levels
b. Nutritional deficiencies
c. Weight gain
d. Increased body fat stores
8. A client with hypovolemia experiences activation of the rennin angiotensin system to maintain
blood pressure. The nurse kows that as part of this response, the endocrine system will have
increased production and secretion of which mineralocorticoid?
a. Aldosterone
b. Adrenocorticotropic hormone
c. Cortisol
d. Glucagon
9. A client with medullary carcinoma of the thyroid gland has an excess function of the C cells of
the thyroid gland. The nurse interprets that this client is primarily at risk of having abnormalities
of which of the following electrolytes?
a. Sodium
b. Potassium
c. Calcium
d. Magnesium
10. A client has abnormal amounts of circulating thyronine and thyroxine. The nurse understands
that the client may have a deficiency of which of the following dietary elements?
a. Calcium
b. Magnesium
c. Phosphorus
d. Iodine
11. A client with endocrine disorder has weight loss and tachycardia. The nurse determines that
which of the following glands is most likely responsible for these symptoms?
a. Thyroid
b. Parathyroid
c. Adrenal cortex
d. Pituitary
12. A nurse overhears a discussion about a client who has an altered production of cortisol. The
nurse plans care knowing that the client is experiencing difficulty with synthesis of which of the
following types of substances?
a. Androgens
b. Catecholamines
c. Glucocorticoids
d. Mineralocorticoids
13. A client’s serum calcium level is high. The nurse plans care knowing that which of the following
hormones is directly responsible for maintaining the free or unbound portion of the serum
calcium within normal limits?
a. Thyroid hormone
b. Parathyroid hormone
c. Follicle stimulating hormone
d. Adrenocorticotropic hormone
14. A client has a tumor that is interfering with the function of the hypothalamus. The nurse would
expect that the client would exhibit which of the following clinical problems?
a. Glucocorticoid excess or deficit
b. Mineralocorticoid excess or deficit
c. Antidiuretic hormone excess or deficit
d. Melatonin excess or deficit
15. A client is diagnosed with dysfunction of the adrenal medulla. The nurse monitors for changes in
client status related to altered production and secretion of which of the following substances?
a. Cortisol
b. Epinephrine
c. Aldosterone
d. Androgens
16. A client has impaired function of the posterior pituitary gland. The nurse plans care knowing
that the client may exhibit altered secretion of which of the following hormones?
a. Antidiuretic hormone
b. Growth hormone
c. Follicle stimulating hormone
d. Luteinizing hormone
17. A client has an endocrine system dysfunction of the pancreas. The nurse plans care knowing
that the client will exhibit impaired secretion of which of the following substances?
a. Amylase
b. Lipase
c. Trypsin
d. Insulin
18. The student nurse is discussing hormones secreted by the posterior hypothalamus to his patient
who has problems with the gland. The student nurse is correct when he states which of the ff
hormone is secreted by the posterior pituitary gland?
a. Anti-diuretic hormone (ADH)
b. Adreno-Cortico Tropic Hormone (ACTH)
c. Prolactin
d. Adreno-Cortico Tropic Hormone (ACTH)
19. The nurse is performing an assessment on a client with a diagnosis of myxedema
(hypothyroidism). Which of the following assessment findings would the nurse expect to note in
this client?
a. Thin, silky hair
b. Dry skin
c. Fine muscle tremors
d. Bulging eyeballs
20. The nurse is performing an assessment on a client with a diagnosis of hyperthyroidism. Which
finding would the nurse expect to note in this client?
a. Periorbital edema
b. Coarse facial features
c. Dry skin
d. Bulging eyeballs
21. The nurse is reviewing the laboratory results of a client with a diagnosis of Cushing’s syndrome.
Which laboratory finding would the nurse most likely expect to note in this client?
a. A blood glucose level of 110 mg/dl
b. A potassium level of 5.5 mEq/L
c. A WBC count of 6000 cells/microL
d. A platelet count of 200,000/microL
22. The unconscious client arrives in the emergency room. The spouse informs the client has DM. a
blood glucose level reads 40 mg/dl. Which of the ff medications is expected to be given?
 a. Regular insulin
b. Glucagon
c. Diabeta
d. NPH insulin
23. The nurse is providing instructions to a client with a diagnosis of Addison’s disease regarding the
administration of prescribed glucocorticoids the nurse instruct the client
a. To avoid taking the medication if nausea occurs
b. To stop the medication if side effect occurs
c. That minimal side effects will occur from the use of this medication
d. That an increase dose of medication may be needed during times of stress
24. The client with DM reports to the health care clinic for glycosylated hemoglobin A1C level.
Which of the ff laboratory results indicate client compliance with the prescribed diabetic
regimen?
a. 5%
b. 8%
c. 10%
d. 15%
25. A nurse has developed a nursing diagnosis of Risk for Disturbed Body Image for a client with
diagnosis of Cushing’s syndrome. The nurse identifies nursing diagnosis and includes this
intervention in the plan of care. Which of the ff is an inappropriate nursing intervention?
a. Encourage client expressions of feelings
b. Assess the client’s understanding of the disease process
c. Encourage the family members to share their feelings about the disease process
d. Encourage thee client to understand that the body changes need to be dealt with
26. A nurse is providing instructions to a client newly diagnosed with DM regarding insulin
administration. The physician prescribed a mixture of NPH and regular insulin. The nurse would
instruct the client that the first step is to
a. Inject air to the amount of NPH insulin prescribed into the vial of NPH insulin
b. Inject air equal to the amount of regular insulin prescribed into the vial of regular insulin
c. Draw up the correct dosage of regular insulin into the syringe
d. Draw up the correct dosage of NPH insulin into the syringe
27. A nurse is caring for a client ff an adrenalectomyand is monitoring for signs of adrenal
insufficiency. Which of the ff if noted in the client would indicate signs and symptoms related to
insufficiency?
a. Subnormal temperature
b. Hypotension and fever
c. Mental status change and hypertension
d. Complaints of weakness and hypertension
28. A nurse is monitoring a client ff thyroidectomy for signs of hypocalcemia. Which of the ff signs if
noted in the client, most likely would indicate the presence of hypocalcemia
a. Tingling aroud the mouth
b. Flaccid paralysis
c. Negative Chvostek’s sign
d. Bradycardia
29. A nurse is monitoring a client with Grave’s disease for signs of thyrotoxic crisis (thyroid storm).
Which of the ff signs and symptoms, if noted will alert the nurse to the presence of this crisis?
 a. Pallor and tachycardia
b. Fever and tachycardia
c. Restlessness and bradycardia
d. Agitation and bradycardia
30. A nurse is reviewing the assessment finding and laboratory data of a client with syndrome of
inappropriate anti diuretic hormone (SIADH) . the nurse understands that which of the ff is not a
characteristic of this disorder?
a. Signs of water intoxication
b. Hypernatremia
c. High urine osmolality
d. Low serum osmolality
31. A nurse is reviewing the assessment findings on a client with a diagnosis of diabetes insipidus
(DI). The nurse understands that which of the ff is unassociated with this disorder?
a. Complaints of excessive thirst
b. Polydipsia
c. Polyuria
d. Concentrated urine
32. A test to measure long term control of DM has been prescribed for a client. The nurse tells the
client that long term control can be measured because chronic high blood sugar level lead to
irreversible glucose binding onto which of the following items?
a. Muscle tissue
b. Adipose tissue
c. Red blood cells
d. Platelets
33. A client
34. D is admitted with a diagnosis of Addison’s disease. The nurse would assess for which of the ff
associated problems with this disorder?
a. Hypotension
b. Hirsutism
c. Obesity
d. Edema
35. A client has begun medication therapy with propylthiouracil (PTU). The nurse would asses the
client for signs and symptoms of which of the ff adverse effects of this medication?
a. Joint pain
b. hypothyroidism
c. Renal toxicity
d. hyperglycemia