Castillo, MH; Celis, MJL; Rodriguez, S Submitted: October 01, 2018
Section 2 Group 3
PH 180 (Epidemiology)
Laboratory Exercise 5
Characterizing Study Designs
Study Design Advantages Disadvantages
Cross-sectional Study • Less costly and time to • No temporal sequence
conduct between exposure and
• Determines the magnitude of outcomes
disease or disease prevalence • No direct estimates proxy for
• Good for multiple exposure risk or rate ratio
• Good for multiple outcomes • Inefficient for rare outcomes
• Use of group level data • Migration can bias
• Useful for establishing interpretation of data
baseline data • Influenced by rate
• Useful for evaluating impact (incidence) and duration of
of community level health outcomes
intervention
• Odds ratio provides estimate
of risk or rate ratio
Cohort Study • Good for rare exposure • Expensive and time
• Good for multiple outcomes consuming
• Directly estimates risks and • Inefficient for rare outcomes
rates • Loss to follow up
• Provides temporality
between exposure and
outcomes
• Maximize exposure
differences among
communities
• Use of group level data
Case-Control Study • Good for rare outcomes • Not good for rare exposures
• Less costly and time to • No direct estimates proxy for
conduct risk or rate ratio
• Use for disease with long • Problem in external
induction and latent period validity and
generalizability
Experimental Study • Use to test new drug or • Expensive and time
medical treatment consuming
• Random allocation of subject • Ethical consideration is
• Strongest evidence of strongest
causality or causal inference • Results cannot be
generalized to individual
• Problems in external validity
and generalizability
Ecologic Study • Use of group level data • Results cannot be
• Useful for evaluating impact generalized to individual
of community level • No direct estimates proxy for
intervention risk or rate ratio
• Less costly and time to • Migration can bias
conduct interpretation of data
• Random allocation of • No temporal sequence
subjects between exposure and
outcomes