PHINMA UNIVERSITY OF PANGASINAN

COLLEGE OF HEALTH SCIENCES

DRUG STUDY
DRUG NURSING
DRUG INDICATION ACTION CONTRAINDICATION ADVERSE EFFECT
INTERACTION CONSIDERATION
Generic Name: >used to treat certain >sulfamethoxazole > >contraindicated in >CNS: headache, >before giving the drug
co-trimoxazole bacterial infections inhibits formation of patients hypersensitivity depression, aseptic ask the patient if he/she is
such as pneumonia (a dihydrofolic acid from to trimethoprim or meningitis, tinnitus, seizures, allergic to sulfa drugs.
lung infection), PABA; trimethoprim sulfonamides. hallucinations, ataxia, >obtain specimen fo
bronchitis (infection inhibits dihydrofolate >contraindicated in nervousness, fatigue, vertigo culture and sensitivity test
those with creatinine, and insomnia before first dose. Therapy
of the tubes leading to reductase formation.
Brand Name: the lungs), and Both decrease
clearance less than >CV: thrombophlebitis may begin while awaiting
Bactrim 15ml/min. porphyria, or >GI: N/V, diarrhea, results.
infections of the bacterial folic acid megaloblastic anemia abdominal pain, anorexia, >Alert: double check
urinary tract, ears, synthesis; from folate deficiency. stomatitis, pancreatitis, dosage as trimethoprim
and intestines. It is bactericidal. >contraindicated in pseudomembranous colitis. component.
also used to treat pregnant women at >GU: toxic nephrosis with >Alert: “DS” product
Drug traveler’s diarrhea. term, breast-feeding oliguria, and anuria, means “double strength”
Classification: women, and infants crystalluria, hematuria, >never give drug I.M.
younger than age intestinal nephritis >monitor renal and liver
Pregnancy risk 2months. >Hematologic: function test results.
category C >use cautiously and in agranulocytosis, aplastic >promptly report rash,
reduced dosages in anemia, megaloblastic sore throat, fever, cough,
patients with creatinine anemia, thrombocytopenia, mouth sores, or iris lesions.
clearance of 15-30 leukopenia, hemolytic Early signs and symptoms
ml/min., severe allergy or anemia. of erythema multiforme.
bronchial asthma, G6PD >Hepatic: jaundice, hepatic Which may progress to SJS
deficiency, or blood necrosis which is sometimes fatal.
dyscrasia. >Musculoskeletal: This symptoms may also
arthralgia, myalgia represent early signs of
>Respiratory: pulmonary blood dyscrasias.
infiltrates >watch signs and
>Skin: erythema multiforme, symptoms of super
Steven Johnson syndrome infection such as fever,
>Other: hypersensitivity chills and increased pulse.
reactions, serum sickness,
drug fever, anaphylaxis.

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