Reliability

Designed to ensure high data precision

Based on its outstanding achievements and many years of
experience in the manufacture of automated biochemical analyzers,
Canon Medical Systems has developed the TBA-2000FR, which represents
a new concept in ultimate functionality.
In addition to the incorporation of high-precision units that have
proven themselves in previous models, the TBA-2000FR provides
high reliability, stable data precision, and safety-conscious design, including an
enhanced data checking function, minimal sample carry over,
and cover open/closed sensors.

Incorporating the high-precision

units of previous models

Enhanced data Minimal sample carryover

checking functions

Open/closed sensors for the top cover,

reagent carousel covers, and STAT position cover
 Simple

Optimized to ensure simple operation

Ensuring that highly reliable data is obtained by
simple operation... This concept has been realized in the
sophisticated design of the TBA-2000FR.
Simplified calibration and control measurement using barcodes,
urgent sample measurement on the rack sampler and at
the STAT position, an integrated multi-ion sensor for easy
maintenance, and many other user-friendly features are
provided to ensure efficient and accurate analysis.

Calibration and control measurement

using barcodes

Rack sampler on Integrated multi-ion sensor

the front of the system

STAT position
 Ecology

Developed to ensure a low environmental impact

Effectively utilizing space, reducing waste, and minimizing
negative impact on the environment...
The TBA-2000FR incorporates many environmentally
friendly features. It is an earth-friendly system that has been
developed based on a wide range of ecological considerations,
including a compact and space-saving design and
the extensive use of recyclable materials.

Integration of the console

and the analyzer module

Shift from air to sea Materials selected to

transport for exported promote recycling
systems to reduce CO2 (reduced use of resin materials)
emissions

Molded hard-glass
reaction cuvettes
Extremely Smooth
The sample racks and trays can be set safely and smoothly on the rack sampler
on the front of the system. High sample throughout is ensured by simple operation.

The rack sampler is on the front of the system

to increase measurement efficiency.
The rack sampler on the front of the system allows the user to
open the sampler cover and add samples even while measure-
ment is being performed. The rack sampler can be accessed
without opening the top cover of the analyzer module, and
samples can be set safely and with no danger of being hit by
the sampling arm or other moving parts.

Samples are recognized reliably by double-checking

The cup sensor detects the presence of a sample cup and
sample tube, and the barcode reader then reads the sample IDs
to identify the samples with high reliability.

Completion of sampling can be confirmed at a glance

Racks for which sampling has been competed are moved to
the left end of the sampler. This allows the user to easily
confirm that sampling has been completed before removing
the samples.

Set the tray on the rack sampler The rack at the left end is loaded into The rack is moved to the left and Racks for which sampling has been
and start measurement. the analyzer, and the cup sensor sampling is performed. competed are pushed out of the analyzer
recognizes the samples. The barcode and moved to the left end of the sampler.
reader then reads the sample IDs.

Racks and trays Sample containers

The racks (each of which can hold up to 5 samples) are placed on Sample tubes of various sizes and
trays and set on the sampler. Up to 10 racks can be placed on a tray, sample cups can be used in combination.
and up to 4 trays (200 samples) can be set on the sampler.

Sample rack END rack*

Rack: 5 samples Tray: 10 racks

* The END rack is set at the final position of the racks and
allows quick measurement of additional samples.
Extremely Flexible
The TBA-2000FR supports simplified calibration and control measurement using barcodes
and flexible urgent sample measurement, ensuring efficient analysis.

Calibration and control measurement

using barcodes
Calibrators and controls can be measured by simply placing
sample cups containing the calibrators or controls on top of
sample tubes to which dedicated barcodes have been applied
and setting them in the sample rack. This minimizes screen
operations and increases efficiency in daily operation.

Support of urgent sample measurement

with the rack sampler and STAT position
An urgent sample can be measured without delay by replacing
a rack on the rack sampler with a rack containing the urgent
sample or by setting the sample at the dedicated STAT
position.

Sample replacement on the rack sampler

The racks on the rack sampler are drawn into the analyzer
immediately just before sampling. An urgent sample can be
measured with high priority by simply replacing the rack to the
right of the drawing position with the rack containing the
urgent sample.

STAT position for processing a STAT sample

with top priority
A STAT position for urgent samples is provided. Sample
barcode reading is possible at this position, and measurement
is performed immediately for the sample set at the STAT
position, interrupting sampling of the routine samples in the
other racks. The tray open/close sensor at the STAT position
allows STAT samples to be set safety by preventing
interference with the sample arm.
STAT position

Quick and easy setting of additional samples

The END rack that interrupts rack drawing and the RESTART
switch allow additional samples to be set with ease.
This feature minimizes user operations.

Additional samples Additional samples

END rack
END rack
Rack drawing
is interrupted

RESTART switch

Rack drawing is interrupted when Set the rack containing additional samples and move Press the RESTART switch to resume
the system detects the END rack. the END rack to the right of the newly added rack. measurement.
Extremely Precise
The TBA-2000FR incorporates various functions to ensure that highly precise data is consistently
obtained. Its extremely reliable analysis results satisfy a wide range of clinical needs.

Sample clot detection function Highly efficient reagent carousels that

provided as standard permit the use of different bottle sizes
The sample clot detection unit monitors the pressure during in combination
sample aspiration and dispensing and detects any abnormali- The double-turntable reagent carousels ensure highly efficient
ties in the pressure waveform. If cloggings in the sample probe reagent dispensing. It is possible to set reagent bottles of
due to fibrin and other obstacles are detected, an error is various sizes in combination.*1 The reagent carousel cover
output and the sample probe is washed automatically. open/close sensor prevents the reagent probes from hitting
Sampling of the next sample is started when the pressure the cover.
returns to normal levels.
Reagent bottle sharing, reagent bottle
Sample clot detection pressure waveform changeover
Normal Abnormal Each of the two reagent carousels can accept
up to 65 reagent bottles*2

Aspiration pressure

Aspiration pressure
All reagent bottle positions are refrigerated,
and universal reagents are supported.
*1: 100, 90, 70, 55, 50, 20 mL (round type, 70-mL type, 55-mL type)
*2: When the reagent rack for 55-mL bottles is used

Time The system detects an abnormality Time

in the waveform and issues an error.

Sample carryover reduced to

0.1 ppm or less
Sample carryover is reduced to 0.1 ppm (1/10,000,000)*1 or less
by the enhanced sample probe wash operation. It is no longer
necessary to divide a sample into small portions for use in an
immunoassay system.
*1: For example, even when a negative sample containing 0 IU/mL of HBs antigen
is measured followed by a sample containing 100,000 IU/mL of HBs antigen,
the result for the negative sample will be 0.01 IU/mL of HBs antigen or less.

*2: Consult with the manufacturer of each immunoassay system for the level of
sample carryover that is considered to be clinically acceptable.

Carryover Sample carryover data

(ppm)

Photometry with a minimum final

reaction volume of 80 μL
The minimum required reaction volume for undiluted
samples is reduced, which also reduces the amount
of reagent required. In addition, this feature
provides improved data precision, extending the
range of applications.
 Molded hard-glass reaction cuvettes Thorough reaction cuvette washing
Extremely Efficient with high washing efficiency
The TBA-2000FR uses molded hard-glass reaction cuvettes that
with the washing unit
After measurement, the reaction cuvettes are washed
The TBA-2000FR is the realization of Canon Medical Systems' many years of expertise in can be washed effectively. After measurement, the reaction thoroughly with two different types of detergents (alkaline and
automated biochemical analyzers. High-order integration opens up many new possibilities. cuvettes are washed thoroughly with two different types of acid) and deionized water before they are used for the next
detergents and deionized water before they are used for the sample. The detergent bottles can be set in the system as is
next sample. In addition, a cuvette blank is measured before because the detergents are diluted automatically, saving time
sample measurement, and cuvettes with a cuvette blank value and effort.
Canon Medical Systems' original electrolyte Vibration-type piezoelectric stirrers higher than the specified value are skipped automatically, with
measurement unit installed as standard for effective mixing of the reaction liquid a beep to indicate an error. The high durability of the reaction
cuvettes reduces the need for periodic replacement and
Canon Medical Systems' original integrated multi-ion sensor High-performance vibration-type stirrers with piezoelectric
minimizes waste.
can simultaneously measure three electrolytes (Na+, K+, Cl-) in elements are used to mix the reaction liquid effectively.
serum or urine and is designed for easy maintenance. The The stirrers cause the liquid to move up and down
Smart Report function displays the measurement results as in the reaction cuvette, ensuring that it is thoroughly mixed.
soon as they become available. In addition, the stirrers have a simple design for easy
maintenance.

Commitment to developing OSS* function to minimize reduction

environmentally friendly products in the processing speed
The TBA-2000FR is designed to be environmentally friendly, The carryover pair program includes additional washing
and its structural components have been carefully selected to processes and consequently reduces the effective processing
minimize negative impact on the environment and waste speed. To minimize this effect, the OSS function automatically
generation. The system is based on environmentally conscious rearranges the sampling sequence to reduce the number of
product development concepts that aim to promote the most times the carryover pair program needs to be executed.
effective use of resources, to reduce the use of potentially * OSS : Optimized Sampling Sequence
harmful substances, and to avoid contributing to global
warming.
Extremely Smart
Smart functions are implemented in a compact unit.
The TBA-2000FR supports user-friendly and powerful functions in daily operation.

Space-saving design by integrating Assay View screen for confirmation

the control console with the of calibration curves
analyzer module The system can store calibration curves for the last 31 days.
The console, which is separated from the analyzer module in This allows the user to compare the current calibration curves
conventional models, is integrated with the analyzer module with the previous curves on the same screen for confirmation.
for further space saving. The combination of an easy-to- In addition, the calibration data can be displayed in graphical
operate LCD monitor with a touch panel and a mouse for form, which is useful for checking for variations in reagent
detailed setting improves user friendliness. blank data or calibrator data.

1896 mm

TBA-2000FR

Approx. 2530 mm

Conventional
model

Recalculation using different conditions

The system stores the absorbance data for all 16 wavelengths, and
Flex Rate function for reducing the measurement results can therefore be recalculated easily after
the retest ratio the assay parameters or calibration curve are changed. This is also
For high-concentration samples that require retesting after useful when evaluating a new assay.
dilution, the Flex Rate function calculates the concentration
based on the absorbance data in the early stages of the read Automatic startup/automatic shutdown
timing and reports the result. This minimizes the retest ratio
The system can be automatically started up and shut
and consequently reduces the reporting time and operating
down at scheduled times. It is also possible to set the
costs.
system so that the power is turned off automatically after
shutdown.
Flex Rate function
ABS External data output to a USB flash drive
The measurement results, absorbance data, QC data, assay
parameters, etc. can be exported to a USB flash drive.

S R1 R2 t

① Flex Rate read timing ② Main read timing

 Automated Biochemical Analyzer

Examples of assays Specifications Installation layout example

Maximum number of assays that 100
can ordered simultaneously NEMA outlet
Proteins and immunoglobulins Carbohydrates Tumor markers 3-pin outlet
Maximum throughput Photometric assays: 1600 tests/hour
Total protein TP Glucose Glu α1-Antitrypsin α1AT High-concentration
ISE assays: 600 tests/hour waste tank
Albumin Alb Sialic acid SiA Carcinoembryonic antigen CEA
Analysis methods Endpoint, Rate, and ISE Drain
Haptoglobin HP Fructosamine FRA α1-Acid glycoprotein α1AGP Deionizer
Sample dispensing volume 1.5 to 35.0 μL/test (in 0.1-μL increments) (*)
C1 inactivator C1 IA Serum 1,5-anhydroglucitol 1.5AG α-Fetoprotein AFP
The sample clot detection function is provided
Thymol turbidity test TTT Glycohemoglobin HbA1c Ferritin Fer in the standard configuration.
Zinc sulfate turbidity test ZTT Glycoalbumin GA Immunosuppressive acid protein IAP Sample carryover 0.1 ppm or less TBA-2000FR
Biochemical analyzer
Myoglobin Mb β2-Microglobulin β2mG Reagent dispensing volume R1: 20 to 278 μL (in 1-μL increments)
IgA, G, M IgA,G,M Enzymes Prostate-specific antigen PSA R2: 0, 20 to 200 μL (in 1-μL increments) Pipeline
IgE IgE Aspartate aminotransferase AST Final reaction volume 80 to 280 μL
Rack sampler
Power line
Complement 3 and complement 4 C3, C4 Mitochondrial AST ASTm Blood coagulation factors and fibrinolytic agents Signal line
Rack sampler 200 samples
C-reactive protein CRP Alanine aminotransferase ALT Antithrombin III AT III The cup sensor and sample ID unit are provided Pipeline
Rheumatoid factor RF Alkaline phosphatase ALP Coagulation factor XIII F XIII in the standard configuration. One of the two directions
can be selected.
Antistreptolysin O ASO Acid phosphatase ACP Plasminogen Plg STAT position 1 position Unit: mm

Complement activity CH50 Adenosine deaminase ADA Fibrin degradation products FDP Sample containers Sample tubes, sample cups * : provided
A circuit breaker is provided on the back of the system. Sufficient clearance should be
behind the system to allow access to the circuit breaker.
Serum antitreponemal antibody TPLA Aldolase ALD α2-Plasmin inhibitor α2PI Reagent carousels R1: 56 bottles (maximum 65 bottles when the
reagent rack for 55-mL bottles is used)
Antilipid antibody RPR Amylase AMY D-dimer D-dimer
R2: 56 bottles (maximum 65 bottles when the
Cystatin C Cys-C Pancreatic amylase AMYp Fibrinogen Fib reagent rack for 55-mL bottles is used) Only Canon Medical Systems specified detergents and ISE solutions should
Guanase GUN Reagent bottles 100 mL, 90 mL, 70 mL, 55 mL, 50 mL, 20 mL be used. The use of detergents or ISE solutions other than those specified
Nonprotein nitrogen compounds γ-Glutamyl transpeptidase γGT Drugs may lead to system malfunction or abnormal data.
Reaction disk Discrete type
Urea nitrogen UN Creatine kinase CK Phenobarbital PBT Reaction cuvettes Hard glass (optical path length: 5 mm)
Uric acid UA CK isozymes (CK-MB) CKMB Primidone PRM Reaction time Approx. 10 min
Creatinine CRE Cholinesterase CHE Phenytoin PHI Method for maintaining Water bath
Creatine CRET Lactic dehydrogenase LD Carbamazepine CBZ isothermal conditions
Ammonia NH3 α-Hydroxybutyric acid dehydrogenase HBD Ethosuximide ESM Reaction temperature 37˚C
Total bilirubin T-Bil Monoamine oxidase MAO Valproate VLP Stirring Piezoelectric stirrers (at two positions)
Direct bilirubin D-Bil Lipase Lip Theophylline TPR Wavelengths 16 wavelengths ranging from 340 to 804 nm
Leucine aminopeptidase LAP Digoxin DIG Photometry Direct photometry of reaction cuvettes,
monochromatic or bichromatic measurement
Lipids β-N-acetylglucosaminidase NAG Cyclosporin A CSA
Online interface RS-232C
Triglycerides TG Gentamicin GM
Data processing functions
Phospholipids PL Electrolytes and minerals
Multipoint calibration curve, display of calibration curve expiration
Free fatty acids FFA Sodium Na Other date, calibration curve log, automatic calibration, reaction time
course (33 points), display of remaining reagent/detergent volumes,
Total cholesterol T-Cho Potassium K Urinary albumin U-Alb reagent bottle changeover, reagent bottle sharing, skipping of
Free cholesterol F-Cho Chloride Cl Occult blood in stool HbAo insufficient reagent, skipping of insufficient sample, obstacle detection,
quality control (daily QC, monthly QC, real-time QC), Smart Wash,
HDL-cholesterol H-Cho Calcium Ca Amino acid BTR reaction test, Flex Rate, skipping of inappropriate cuvette, multiple
LDL-cholesterol L-Cho Magnesium Mg Urinary total protein U-TP measurement, automatic sample dilution, automatic retest order,
Smart Report, OSS, recalculation, color correction, serum indices,
β-lipoproteins β-Lipo Inorganic phosphorus IP Inulin Inulin calculation between assays, process monitor, automatic startup,
ApoA-I ApoA-I Serum iron Fe Remnant-like particle cholesterol RLP-C automatic shutdown, cuvette analyzer, multiassay,
registration of user IDs/passwords, lamp intensity monitor
ApoA-II ApoA-II Unsaturated iron-binding capacity UIBC *Assays currently under investigation are included.

ApoB ApoB Transferrin Tf External dimensions* Analyzer module

1896 (W) x 1150 (D) x 1437 (H) mm
ApoC-II ApoC-II Serum copper Cu
Mass* Analyzer module Approx. 780 kg
ApoC-III ApoC-III
Power supply Analyzer module 200 VAC
ApoE ApoE
Power consumption Analyzer module 3 kVA maximum
Total bile acid TBA
Options Reagent rack for 55-mL bottles
Serum lipoprotein (a) Lp(a)
Reagent barcode unit

* The console is included in the analyzer module.

[Link]
©Canon Medical Systems Corporation 2011-2018. All rights reserved.
Design and specifications are subject to change without notice.
MCACL0008EAA 2018-08 CMSC/D/Printed in Japan

Canon Medical Systems Corporation meets internationally recognized

standards for Quality Management System ISO 9001, ISO 13485.
Canon Medical Systems Corporation meets the
Environmental Management System standard ISO 14001.
TBA and Made for Life are trademarks of Canon Medical Systems Corporation.
Other company and product names appearing in this document may be
trademarks or registered trademarks of their perspective holders.