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Antibiotic and Antifungal Drug Overview

This document provides information on two drugs - trimethoprim/sulfamethoxazole and fluconazole. It lists the generic and brand names, class, mechanism of action, indications, contraindications, dosing, administration route, and nursing responsibilities for each drug. Nurses are responsible for assessing patients before, during, and after administration to monitor for adverse effects and ensure proper administration and education.

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0% found this document useful (0 votes)
79 views3 pages

Antibiotic and Antifungal Drug Overview

This document provides information on two drugs - trimethoprim/sulfamethoxazole and fluconazole. It lists the generic and brand names, class, mechanism of action, indications, contraindications, dosing, administration route, and nursing responsibilities for each drug. Nurses are responsible for assessing patients before, during, and after administration to monitor for adverse effects and ensure proper administration and education.

Uploaded by

SALWA
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

DRUG NAME MECHANISM OF ACTION INDICATION / ADVERSE NURSING RESPONSIBILITIES

CONTRAINDICATION EFFECT

BEFORE:
GENERIC NAME(S): These two components of INDICATION: GI: diarrhea,  Assess for v/s &history of
Trimethoprim / Sulfamethoxazole the antibiotic inhibit combination is used to treat anorexia, allergy
BRAND NAME: enzyme systems involved infections such as urinary tract nausea,  Assess blood glucose & fluid
Bactrim in the bacterial synthesis to infections, middle ear vomiting electrolyte levels
CLASS: prevent infections that may infections CNS: dizziness,  assess the site before
Therapeutic: antibiotic occur due to lower the headache, administration.
Pharmacologic: sulfonamide and immunity system that lethargy DURING:
folate antagonist caused by anti-rejection DERMA:  Assess the injected site
meds. Rushes, red  Instruct patient to immediately
DOSING: 8 to 10 mg CONTRAINDICATION: skin lesions report unusual bleeding or
FREQUENCY: IV in 2 to 4 equally in patients with a known Rushes
divided dose hypersensitivity to AFTER:
ROUTE: IV trimethoprim or sulfonamides,  Educate patient of potential
in patients with a history of adverse reactions.
drug-induced immune  As appropriate, review all other
thrombocytopenia with use of significant and life-threatening
trimethoprim and/or adverse reactions and
sulfonamides, and in patients interactions, especially those
with documented related to the drugs
megaloblastic anemia due to
folate deficiency
DRUG NAME MECHANISM OF ACTION INDICATION / ADVERSE NURSING RESPONSIBILITIES
CONTRAINDICATION EFFECT

BEFORE:

GENERIC NAME(S): is effective antifungal INDICATION: GI: nausea,  Assess for v/s &history of allergy
prophylaxis after kidney vomiting,
Fluconazole Use to prevent fungal  Assess for S/S of infection. Ensure
transplantation without abdominal
infections formulation can be given by
BRAND NAME: significant effects on pain, diarrhea
prescribed route
tacrolimus trough levels or
Diflucan/Dyzolor CNS: headache,
overall exposure DURING:
CLASS: Seizures,
 Infuse IV only; not intended for IM or
Therapeutic: antifungals DERMA: subcutaneous use Instruct client to
CONTRAINDICATION Rushes, foliate swallow the tablets whole. & Do not
Pharmacologic: Bis triazole skin disorder
: break, crush, or chew them.
derivative
Hypersensitivity to  Administer through sterile equipment
DOSING: 50 mg
fluconazole, other
AFTER:
ROUTE: PO azole antifungals, Co
administration with  Educate pt. Drugs may be given orally
cisapride and or IV as needed. The drug will need to
terfenadine be taken for the full course and may
need to be taken long term

 Evaluate patient for adverse reactions

 Encourage to repot the experience


side effect such as rash, changes in
stool or urine color, difficulty
breathing.

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