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DS Losartan

Losartan is an angiotensin receptor antagonist used to treat hypertension. It works by blocking the binding of angiotensin II to receptors, antagonizing its effects including vasoconstriction and aldosterone release. The standard dosage is 50mg twice daily for hypertension. Common side effects include dizziness, headache, diarrhea and muscle cramps. Nursing alerts include monitoring blood pressure before administration and drug effectiveness, and instructing patients not to stop taking the drug without doctor's orders.

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Yuuki Chitose (tai-kun)
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344 views1 page

DS Losartan

Losartan is an angiotensin receptor antagonist used to treat hypertension. It works by blocking the binding of angiotensin II to receptors, antagonizing its effects including vasoconstriction and aldosterone release. The standard dosage is 50mg twice daily for hypertension. Common side effects include dizziness, headache, diarrhea and muscle cramps. Nursing alerts include monitoring blood pressure before administration and drug effectiveness, and instructing patients not to stop taking the drug without doctor's orders.

Uploaded by

Yuuki Chitose (tai-kun)
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

Name of the Mechanism of Action Dosage Indication Contraindication Adverse Nursing Alert

Drug Reaction
LOSARTAN Losartan administration 50mg Hypertension Hypersensitivity CNS [Link] BP
POTASSIUM results in a decrease in total BID Treatment of to losartan Dizziness, prior to the
peripheral resistance and hypertension, Use cautiously insomnia, administration
Classifications: cardiac venous return. All IV alone or in with hepatic or headache. of medication of
cardiovascular of the physiological effects combination renal GI: Diarrhea, scheduled dose
agent; of angiotensin II, including with other dysfunction, dyspepsia. [Link] drug
angiotensin stimulation of release antihypertensive hypovolemia Musculoskeletal: for effectiveness
receptor of aldosterone, are Agents. Muscle cramps, 3. If there is
antagonized in the presence Treatment of myalgia, back or inadequate
antagonist;
of losartan. Reduction in diabetic leg pain. response split
antihypertensive blood pressure occurs neuropathy with Respiratory: the daily dose in
independently of the status Nasal a day is into
an elevated
of the renin-angiotensin congestion, twice daily is
system. As a result of serum recommended
cough, upper
losartan dosing, plasma creatinine and 4. Lab tests:
respiratory
renin. Activity increases proteinuria in infection, Monitor CBC,
due to removal of the patients with sinusitis electrolytes,
angiotensin II feedback. type 2 diabetes liver & kidney
Selectively blocks the and a history function with
binding of angiotensin II to long-term
of hypertension
specific tissue receptors therapy.
found in the vascular 5. Inform client
smooth muscle and adrenal to not stop
gland; this action blocks the taking this drug
vasoconstriction effect of without doctors
the renin-angiotensin order
system as well as the release 6.  Report fever,
of aldosterone leading to chills, dizziness
decreased blood pressure.

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