DRUGS AND THEIR
SPECIFIC SYNDROMES
S. NO. NAME OF DRUG SYNDROMES/ADVERSE EFFECT
1. Aspirin Reye’s syndrome
e s
2. Chloroquine Irritable bowel syndrome
s s
3. Montelukast and Churg Strauss syndrome
4.
Zafirlukast
c c la
d
Oral contraceptives Cushing’s syndrome
g
5. Calcium carbonate Milk alkali syndrome
t @
6. Pethidine ‘Serotonin syndrome’
7.
ig h
Haloperidol or pimozide Gilles de la tourette syndrome
r
y
8. Dapsone Sulfone syndrome
o p
9. Adefovir dipivoxil Flu syndrome
c
10. Quiniodochlor Caused a neuropathic syndrome
11. Pemetrexed Hand-foot syndrome
12. Mitomycin C Haemolytic-uremic syndrome
13.
s
Tretinoin ‘retinoic acid syndrome
s e
14. ACE-inhibitors Dry cough
la s
15. Amphotericin- B, Nephrotoxicity
Erythromycin
d c c
g
16. Antipsychotics Sedation, orathostatic, hypotension, tardive dyskinesia
@
17.
t
Atropine Dryness of mouth
h
18.
g
Chlorambucil Alopecia
19.
y r i
Chloramphenicol Grey baby syndrome, bone marrow depression
p
20.
o
Clofazimine Pigmentation of skin discolouration of urine
c
21. Clozapine Agranulocytosis
22. Ethambutol Optic neuritis
23. Isoniazid Peripheral neuritis
s
24. Minoxidil phenytoin anabolic steroids Hirsutism
25. Morphine
s
Constipation
s e
la
26. Penicillin-G Jarischhexiemer reaction
27. Quinidine
d c c
Cinchonism
g
28. Quinine sulphate Black water fever
t @
29. Repaglinide Althralgia
30.
r ig h
Rosiglitazone Anemia weight gain
y
31. Spironolactone, Cimentidine Gynacomastia
o p
32. Streptomycin chloroqune furosemide Ototoxicity (Damage of 8th cranial
c
never)
33. Sulfonylureas derivatives Bone marrow depression
34. Spironolactone, Cimentidine Gynacomastia
s
35. Streptomycin chloroqune furosemide Ototoxicity (Damage of 8th cranial
never)
s s e
la
36. Sulfonylureas derivatives Bone marrow depression
37. Tetracyclines
d c c
Fanconi syndrome, Discolouration of
@ g teeth
t
38.
h
Thalidomide Phocomelia (seal-like limbs )
ig
39.
r
Sulfonamides, Cephalosporin, Stevan-johnson syndrome
o p yAllopurinol
c
40. Metoclopramide, Haloperidol Extrapyramidal reaction
41. Tetracyclines sympathomimetics Pseudotumor cerebri
42. Hydralazine, Blemycin, Asparginase Systemic lupus erythrmatous
e s
syndrome
43. Simvastatin, Daptomycins Myopathy
s s
la
44. Glucocorticoides, Thyroxine, Heparin Osteoporosis
45. β-blocker, Clonidine, Diuretics
d c c
Impotence
g
46. Cephalosporins, Alopurinol Interstitial nephritis
47.
t @
Primaquine, Chloramphenicol
h
Haemolytic anemia
ig
48. Phenothiazianes, TCAs (Tetracyclin) Hyperprolactinemia
49.
p y r
Vancomycin Red man syndrome
o
50. Nitorfurantoin Loffler's syndrome
51.
c Benzocaine, Dapsone Blue baby syndrome
53. Doxorubicin Hand foot syndrome
s
54. Cisplatin and Bleomycin Raynaud syndrome
e
Calcitonin, Phenytoin Hypocalcemia
s
55.
s
Corticosteroids, β-blockers Hypertriglyceridemia
la
56.
c
57. Theophylline, Morphine Hypotension
58.
g
Oral hypoglycemic, Insulin, Quinine
d c
Cocaine, Cyclosporine, MAO inhibitors Hypertension
Hypoglycemia
@
59.
h t
60. Vinca alkaloids, Cyclophosphamide Inappropriate ADH secretion
61.
r ig
Streptomycin
y
Ototoxicity
p
62. Rifampicin Jaundice
63.
64. c o
Bacitracin, Polyenes, Polypeptide Nephrotoxicity
Polymyxin B Neurotoxicity, Nephrotoxicity
65. Anthracycline Cardiotoxicity
(Doxorubicin Daunorubicin)
s
66. Busulphan, Bleomycin Pulmonary fibrorsis
67. Vincristine, vinblastine, Vinorelbine
s
Peripheral neuropathy
s e
la
68. Methotrexate Megaloblastic aneamia, Hepatotoxicity,
c
Obstructive nephropathy
c
69. Cyclophosphamide, Ifosfamide Haemorrhagic cystitis, Alopecia
70.
71.
Cisplatin
g
5-Flourouracil, Capecitabine, d
Emesis, Nephrotoxicity, Neuropathy,
Hand and foot syndrome, Neurotoxicity
t
Fludarabine
h @
g
72. 6- Mercaptopurine, 6-Thioguanine Hepatotoxicity
73.
r i
Paclitaxel, vincristine
y
Peripheral neuropathy,
p
Hypersensitivity
o
74. Docetaxel Peripheral neuropathy, Fluid retention
75.
c Doxyfluridine Bone marrow depression, Hearing loss,
Neuritis.
