Scribd
Upload
1K views2 pages

Pharmacology Key Points and Interactions

This document lists various medical terms and concepts related to pharmacology. It includes information about drug mechanisms of action, side effects, interactions, dosages, and other pharmacokinetic properties. Some key points covered are that bradykinin causes vascular smooth muscle relaxation, atenolol and diltiazem have an additive effect on bradycardia, and morphine 10 mg IV is equivalent to 0.1 mg/100 mcg of fentanyl. It also discusses drug metabolism pathways such as codeine being metabolized by CYP2D6 and aripiprazole interacting with diltiazem through CYP3A4.

Uploaded by

majid tariq
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
1K views2 pages

Pharmacology Key Points and Interactions

This document lists various medical terms and concepts related to pharmacology. It includes information about drug mechanisms of action, side effects, interactions, dosages, and other pharmacokinetic properties. Some key points covered are that bradykinin causes vascular smooth muscle relaxation, atenolol and diltiazem have an additive effect on bradycardia, and morphine 10 mg IV is equivalent to 0.1 mg/100 mcg of fentanyl. It also discusses drug metabolism pathways such as codeine being metabolized by CYP2D6 and aripiprazole interacting with diltiazem through CYP3A4.

Uploaded by

majid tariq
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
  • Pharmacological Notes: This section provides a list of pharmacological notes and quick references on various drugs, their effects, and interactions.

KAPS---July 17, 2022

1. Bradykinin-→ Vascular smooth muscle relaxation.


2. Atenolol + Diltiazem-→ Bradycardia “additive effect”.
3. Productive cough for hypertensive patients----→ Guaiphenesin
4. Protective layer on stomach--→ Sucralfate.
5. Miosis------→ Pilocarpine.
6. Max. dose of Acarbose--→ 600 mg
7. Side effect of aminoglycoside----------→ Nephrotoxicity.
8. Precursor of Histamine---→ Histidine.
9. Compensation of respiratory acidosis --------→ increase HCO3- reabsorption.
10. Penicillin not active against Mycoplasma------→ No cell wall
11. PEG structure
12. Nocturnal anuresis--------→ Imipramine
13. NE to Epinephrine------→ Methylation
14. Osmotic diuretic--------→ Mannitol
15. Amphotericin B-----→ Aspergillosis
16. Vit D----→ Promotes Ca and phosphate absorption
17. Longer time of action-------→ Fentanyl patch
18. Loperamide for----------→ Acute uncomplicated diarrhea
19. Tetanus------- 10years
20. Vit K factors---------→ 2, 7, 9, 10
21. Vitamin similar to steroid----------→ Vit D
22. Not require loading dose----------→ Morphine
23. Cholinergic crisis----------→ Myasteria gravis
24. Lanolin and water calculation ----------→ 50/06
25. Aligation one 30% and 50% to get------------→ 500ml
26. MOA of Atenolol----------→ Decrease Oxygen consumption and decrease cardiac output
27. Precursor of T4--------→ Tyrosine
28. Diphenoxylate---------→ Antidiarrheal
29. Prevention of Asthma------------→ Inhaled Corticosteroid
30. Not used in Aspirin toxixity-------→ Edetate
31. Benefit of T4 or T3 -----------------→ Longer duaration
32. Rate of infusion calculation 936 mg/hr
33. Phenol characteristics
34. Calculation of Cl hepatic extraction ratio
35. Codeine cyto 2D6
36. Methyl paraben methyl ester of
37. Laxative dependence-----→ Bisacodyl
38. Mtronidazole and Alcohol---------→ 24 hrs apart
39. Aripripozole x Diltiazem cyt 3A4
40. Morphine and Fentanyl equivalent----------→ 10 mg IV Morphin = 0.1 mg/100 mcg Fentanyl
41. Phenytoin dose----→ Epilepsy 4-5 mg/kg or Status epilepticus 15-20 mg/kg
42. Annual vaccine ---------→ Flu
43. Phenylethylamine STRUCTURE
44. Otitis media----------→ Amoxicillin
45. Barbituration toxicity---------→ Support respiration
46. Permethin 5%---------→ Scabies
47. Cyp 450 location -----------→ Endoplasmic Reticulum
48. Erythromycin activity due to ---------→ Lactone ring

1
KAPS---July 17, 2022

49. Wooping cough--------→ Erythromycin


50. Warfarin least interact with ----------→ Allopurinol
51. Drug not used for extraction-----→ Alginic acid
52. 30 mg oral morphine is eq to 12 mcg/hr transdermal Fentanyl
53. Diltiazem and Cyclosporin interaction-----→ Increase Cyclosporin
54. Not cellular component-----→ Glucose
55. Verapamil and Erythromycin interaction -----→ Increase verapamil
56. Side effects of Paroxetine-----→ Gynocomastia and Sexual dysfunction
57. Hydrophobic part of protein-----→ Inside
58. Impetigo causes pyelonephritis-----→ Not causes
59. Bioavailability 16%
60. Lanolin 50 g+Water 6 g
61. Lithium 8.12 mmol
62. Rate of infusion 936 mg/hr
63. Vd 40L
64. Lyophilized 7ml
65. Kcl 2mmol
66. Time to reach steady state 12hrs
67. MOA of Corticosteroids-----→Inhibits Phospholipase A2
68. Acamprostate duration-----→3 months
69. Drug having ketone structure-----→Phednisolone
70. Dose adjustment need after smoking-----→Olanzepine
71. Bond Between Organophosphorus and Chlorine-----→Irreversible covalent bond

You might also like