PHARMACEUTICAL BIOCHEMISTRY (PBIO 211)
UNIT 7:
NUTRITION
COLLEGE OF PHARMACY
OBJECTIVES:
At the end of this unit, the students are expected:
1. To demonstrate knowledge regarding the biological basis of nutri
tion and the mechanisms by which diet can influence health
2. To create a correct menu plan for at least a week to show mainte
nance of good eating habits to a healthy living.
OUTLINE:
1. Expenditure of energy
2. Body Mass Index
a. Computation of IBW
B. Computation of BMR
C. Computation of Ideal weight
D. Computation of SDA
E. Computation of TCR
ENERGY REQUIREMENT
EXPENDITURE OF
ENERGY:
Basal metabolic rate – energyexpenditure
necessary to maintain physiologic functions.
Thermogeniceffect
Physical Activity
EnvironmentalTemperature
BODY MASS INDEX
BMI =weight in kg / height in m
1981 JOINT FAO/WHO/UNUCONSULTATION
1. Computefor BMR Note:
bodyweight in kg (W)
5ft 2 in =62 in / 39.37 in =1.57 m=157 cm
157 cm– 100 =57 – (10%of theanswer)
57- 5.7 =51.3
IBW =51.3 kg
Age Range Males kcal/day Females
kcal/day
0-3 60.9 W - 54 61.0 W -51
3-10 22.7 W +495 22.5 W +499
10-18 17.5 W +651 12.2 W +746
18-30 15.3 W +679 14.7 W +496
30-60 11.6W +829 8.7 W +829
>60 13.5W+487 10.5W+596
17 years old=(17.5)(51.3) +651
male =1,548.75kcal
2. BMR IS MULTIPLIED BY THE FACTORS:
Activity lev Male Female
el
Light 1.58 1.45
Moderate 1.67 1.55
Veryactive 1.88
Light Moderate Heavy
Office workers Men in light Agricultural
Most professional Un industry Student worker
employed men Building worker Fisher Soldier active in duty
Housewife with mech men Soldier notactive Dancer
anical household in duty Athlete Mine &steel
appliances Housewife without worker
mechanical househol
d appliances Depart
mentstore
worker
ENERGYREQUIREMENT FOR LIGHT ACTIVITIES
Activity Factor Hours
Bed 1.0 xBMR
Occupational 2.3/1.6 x
BMR
Discretionary 1.8 xBMR
Residual 1.4 xBMR
time
Note:
For moderateactivity,factor for occupational activitie
s is 2.7 xBMR inwomen.
For veryactive activity,factor for occupational activities
is 3.0 xBMR inmen.
The other factors remain the same.
II. FACTORIALMETHOD
1.Determination of IBW
a.Use of standard weight and height tables.
b. Thannhausermethod
Ht. (cm) – 100 less 10%of the obtained valueEx.
160 – 100 =60 kg– (10%of 60 kg)=54 kg
2. Calculation of BMR for 24 hour at 1 kcal/kg/ hour
BMR =1 kcal xIBW x24hours
=1 kcal x54 x24
=1,296kcal/kg/hr
3.Corrected BMR
BMRc =BMR – (0.1 kcal xIBW x#of hoursofsleep)
=1296 – (0.1 kcal x54 x8 hrs ofsleep)
= 1296 – 43.2
=1252.8kcal
4. CORRECTEDPHYSICALACTIVITY
P.A. =BMRC X %OF CORRECTEDBMR
Bedrest 10%
Sedentary 30%
Light 50%
Moderate 75%
Heavy 100%
PA=1,252.8 X0.75
= 939.6 kcal
5.CalculateSpecific Dynamic Action (SDA)
SDA=0.06 (BMRc +PA)
=0.06 (1,252.8 +939.6)
= 0.06(2192.4)
= 131.54 kcal
6. CalculateTotal Caloric Requirement (TCR)
TCR=BMRc +PA+SDA
=1,252.8 +939.6 +131.54
=2, 323.94kcal
TCR for a student, 54 kg (IBW)with 8hrs ofsleep =
2,323.94kcal
III. SHORTMETHOD
Adults Kcal / kg
Bedrest 25
Light 30
Moderate 35
Heavy 40
Children Kcal/lb/IBW
Age1 45
5 35
10 25
15 M 20 F15
1gram 4calories
carbohydrate
1gramprotein 4calories
1gramfats 9calories
Related Links:
1. Nutrition for a Healthy life
- Alliance for Aging Research
https://youtu.be/c06dTj0v0sM
2. Exercise, Nutrition and Health: keeping it si
mple Jason Kilderry
-TED ED
https://youtu.be/qUfWOT3zujY
REMINDERS:
1. Read lectures published in your canvas modules (next topic: E
ndocrine System)
2. Refer to unit terminologies for jargons
3. Participate in weekly discussion
4. Submit assessment tasks (assignments and discussion boards
)
5. Prepare for unit quiz (topic: Nutrition)
Thank you!
