Rajiv Gandhi University of Health Sciences, Karnataka

4th T Block Jayanagar, Bengaluru

Curriculum delivery design of B. Pharm. course of Semester I & II System
w.e.f Academic year 2017-18
SEMESTER-I
BP101T: Human Anatomy and Physiology-I

1. Departmental objectives (what the learners will be able to perform after completing the
subject):
A. Learning Objectives:

Upon completion of this course the student should be able to

a. Explain the gross morphology, structure and functions of various organs of the
human body.
b. Describe the various homeostatic mechanisms and their imbalances.
c. Identify the various tissues and organs of different systems of human body.
d. Perform the various experiments related to special senses and nervous system.
e. Appreciate coordinated working pattern of different organs of each system

2. Content distribution as per the list of topics, time allotted for each topic, distribution for
‘Must know’, ‘Desirable to know’ and ‘Nice to know’ and the probable weightage.

The following table can also be a reference frame for continuous and formative
assessment of learning. If the curriculum management is scheduled as per the
tabulation, there can be clarity for both learners and teachers to take stock of the
mastery achieved in each objective. This will also help for professional excellence that
goes beyond the examination process.

UNIT-I Hours: 10 Weightage: 16 Marks

Learning Topics
content
Introduction to human body, Cellular level of organization, Tissue level
distribution
of organization
Must know Define anatomy and physiology, basic terminologies, planes, body positions
and cavities. Levels of structural organization, body systems, basic life
process,
Structure and functions of cell, cell junctions, general principle of cell
communication,
Desirable to Homeostasis. Cell division (mitosis and meiosis). Intracellular signaling
know pathways activation by extra cellular molecule. Contact –dependent,
paracrine, synaptic and endocrine.
Nice to know Receptors, channels, cell membrane enzymes and mitochondrial enzymes.
Interrelation with each tissue and organs

UNIT-II Hours: 10 Weightage: 16 Marks

Learning Topics
content
Integumentary system, Skeletal system, Joints

1
distribution
Must know Structure and function of skin. Classification of skeletal system, axial and
appendicular skeletal bones-structure, composition, characterstics, functions.
Physiology of skeletal muscle contraction, neuro-muscular junction. Structural
and functional classification of joints, types of joints and its articulations
Desirable to Role of skin in relation with nervous system and defence mechanism
know (immunity). Dermatitis. Bones disorders and etiology. Disorders of joints and
auto immune disorders
Nice to know Skin glands, Mineralization of bone, Hyaluronic acid lubrication

UNIT-III Hours: 10 Weightage: 22 Marks

Learning Topics
content
Body fluids and blood, Lymphatic system
distribution
Must know Composition, functions of blood, haemopoeisis, RBC, WBC-types, function,
platelets, blood groupin, Rh factor( erythroblastosis foetalis) transfusions,
clotting factors, clotting pathways, coagulation mechanisms.
Compostion and function of lymph. Structure and function of lymph node and
spleen, formation and composition of tissue fluid
Desirable to Reticulo endothelial system, disorders of blood and clotting disorders. normal
know value haemoglobin, Normal counts of RBC, different types of WBC and
platelets.
Lymphatic circulation, vessels
Nice to know Bombay blood group, formation of body fluids from blood

UNIT-IV Hours: 8 Weightage: 19 Marks

Learning Topics
content
Peripheral nervous system, Special senses
distribution
Must know Classification of Peripheral nervous system( cranio-spinal nerves, somatic
nervous system and autonomic nervous system), anatomical and
physiological differences between sympathetic and para sympathetic nervous
syStem, origin and functions of spinal nerves and cranial nerves
Structure of eye and physiology of vision.
Structure of ear and physiology of ear (auditory and non auditory)
Desirable to Origin and functions of spinal nerves and cranial nerves.
know Structure and functions of tongue and nose, Disorders- myopia, hyper
metropia, glaucoma, keratitis, cataract, night blindness etc.
Nice to know Neurotransmitters, receptors, signalling pathways, Peripheral nervous system
Neuroglia.

UNIT-V Hours: 7 Weightage: 22 Marks

Learning Topics
content
Cardio vascular system
distribution
Must know External and internal anatomy of heart, conduction system , cardiac cycle,
waves and segments of ECG, blood pressure and regulation of blood

2
 pressure(Renin angiotensin system), factors affecting of regulation.
Desirable to Layers of arterial vessels, structure and functions of arteries, vein and
know capillaries, blood circulation (systemic, pulmonary, coronary and portal) ,
pulse, heart sounds, heart rate, heartbeat, junctional tissues of heart.
Cardiovascular disorders( atherosclerosis, hypertension, hypotension,
myocardial infarction, angina pectoris, cardiac arrhythmias, congestive
cardiac failure
Nice to know Cerebral circulation, cardiac asthma, atrio natriuritic peptide (ANP).

Blueprint of question paper, for each QP. This shows the weightage given to each chapter in
the summative assessment. This improves the content validity by distributing the
assessment of learners in the competencies that are represented by learning objectives
under each chapter.

BLUE PRINT OF MODEL QUESTION PAPER

BP101T: Human Anatomy and Physiology-I
TIME: 3 HOURS MAX. MARKS: 75

Unit No Must know Desirable to know Weightage

Hours

LE SE SA LE SE SA of marks
(10X3) (5X8) (2X5) (10X0) (5X1) (2X5)
Unit-I 10 2 1 _ 2 16
Unit-II 10 - 1 2 _ 1 1 16
Unit-III 10 1 2 _ 1 22
Unit-IV 08 1 1 1 _ 1 19
Unit-V 07 1 2 1 _ - 22
Total 45 30 40 10 - 5 10 95
80 15 95

__________________________

3
BP102T. Pharmaceutical Analysis

1. Departmental objectives (what the learners will be able to perform after completing
the subject):

A. Learning Objectives:

Upon completion of this course the student should be able to

a. Understand the principles of volumetric and electro chemical analysis

b. Carryout various volumetric and electrochemical titrations
c. Develop analytical skills

2. Content distribution as per the list of topics, time allotted for each topic, distribution
for ‘Must know’, ‘Desirable to know’ and ‘Nice to know’ and the probable weightage.

The following table can also be a reference frame for continuous and formative assessment
of learning. If the curriculum management is scheduled as per the tabulation, there can be
clarity for both learners and teachers to take stock of the mastery achieved in each objective.
This will also help for professional excellence that goes beyond the examination process.

UNIT-I Hours: 10 Weightage: 19 Marks

Learning Topics
content
a)Pharmaceutical Analysis
distribution
1) Definition and scope different techanique of analysis
2) Method of expressing concentration
3)Primary and secondary standards
4) Preparation and standardisation of volumetric solutions
b) Errors
Must know Quantitative analysis, Qualitative analysis
Normality, Molarity,Gram equivalent weight, assay, estimation
Definition, examples, Ideal requirements of primary and secondary standards
Preparation of molar and normal solutions of different concentrations and
standardisation Principle and procedures.
Sources of errors, types of errors, methods of minimizing errors, accuracy,
precision and significant figures
Desirable to Definition of Titration, titrant, titrand or titrate, end point
know Mole, relative molecular mass, relative atomic mass
Standards used in different types of titrations
Formulae to calculate Normality, Morality,
Preparation of solutions of different concentrations for example 1N, 0.1N,
0.1M etc and different volumes like 1000ml, 500ml, 250ml of different
concentrations.
Mean, standard deviation, coefficient of variations.
Nice to know Requirements of a titration
Periodic Table
Significance of Statistical methods for Pharmaceutical Analysis

UNIT-II Hours: 10 Weightage: 24 Marks

Learning Topics
content
1)Acid base titration
distribution

4
 2) Non Aqueous titration
Must know Concepts of acids and bases, Theories of acid base indicators, classification of
acid base titrations, neutralization curves, theory involved in titrations of
strong, weak, and very weak acids and bases.
Basic principle, Solvents, acidimetry titration and alkalimetry titration,
estimation of Sodium benzoate and Ephedrine HCl
Desirable to Arrhenius concept, Bronsted Lowry concept, Lewis acids and bases, Ostwald
know theory and modified Ostwald theory, Examples of Indicators, Selection of
Indicators.
Titrants used in non aqueous titrations, levelling effect, differentiating effects,
applications, indicators used.Mean, standard deviation, coefficient of
variations.
Nice to know Equilibrium constant, Strengths of acids and bases, Ionic product of water, pH.
Amphoteric nature of water and disadvantage of water as a solvent.

UNIT-III Hours: 10 Weightage: 19 Marks

Learning Topics
content
a) Precipitation titrations
distribution
b) Complexometric titrations
c) Gravimetry
Must know Mohr’s method, Volhard’s, Modified Volhard’s method, Fajans method,
estimation of sodium chloride.
Basic principles and Classification, metal ion indicators, masking and
demasking reagents, estimation of Magnesium sulphate, and calcium
gluconate.
Principle and steps involved in gravimetric analysis. Purity of the precipitate,
Estimation of Barium Sulphate.
Desirable to Indicators used in precipitation titrations.
know Complexing agents, chelating agents, sequestering agents, ligands and
classification, Preparation and standardisation of EDTA.
Co precipitation and Post precipitation, Ignition, weighing of precipitate,
supersaturation and solubility of precipitate.
Nice to know Solubility Product
Nature and Structure of complexes of metal ions with EDTA
Common Ion Effect

UNIT-IV Hours: 8 Weightage: 14 Marks

Learning Topics
content
Redox titrations
distribution
Must know Concepts of oxidation and reduction, Principles of redox titrations, Cerimetry,
Iodimetry, Iodometry, Bromatometry, Dichrometry, Titration with Potassium
Iodate, Titrations with Potassium Permanganate

Desirable to Redox Indicators, strengths and equivanents of oxidising and reducing agents,
know Preparation and standardisation of Potassium Permanganate.
Nice to know Oxidation numbers, Redox potential

5
 UNIT-V Hours: 7 Weightage: 19 Marks
Learning Topics
content
Electrochemical methods of analysis
distribution
a)Conductometry
b)Potentiometry
c)Polarography
Must know Introduction and Conductivity cell, Conductometric titrations and application.
Electrochemical cell, construction and working of reference and indicator
electrodes methods to determine end point of potentiometric titrations and
applications.
Principle, Ilkovic equation, construction and working of dropping mercury
electrode and rotating platinum electrode and applications.
Desirable to Conductance and Resistance, Molar Conductance and Specific
know Conductance,Cell constant.
Standard hydrogen, silver chloride electrode and calomel electrode, metal
electrodes and glass electrode.
Different types of currents and significance.
Nice to know Cathodes and Anodes
Amperometry

3. Blueprint of question paper, for each QP. This shows the weightage given to each
chapter in the summative assessment. This improves the content validity by distributing
the assessment of learners in the competencies that are represented by learning
objectives under each chapter. State the number of QPs for the subject.

BLUE PRINT OF MODEL QUESTION PAPER

BP102T. Pharmaceutical Analysis
TIME: 3 HOURS MAX. MARKS: 75

Unit No Must know Desirable to know Weightage

Hours

LE SE SA LE SE SA of marks
(10X3) (5X7) (2X6) (10X0) (5X2) (2X4)
Unit-I 10 1 1 1 1 19
Unit-II 10 1 2 1 1 24
Unit-III 10 2 1 1 1 19
Unit-IV 08 1 1 1 14
Unit-V 07 2 2 1 19
Total 45 30 35 12 -- 10 08 95
77 18 95

_____________________________

BP103T. PHARMACEUTICS- I

1. Departmental objectives (what the learners will be able to perform after completing
the subject):
A. Learning Objectives:

Upon completion of this course the student should be able to:

a. Know the history of profession of pharmacy

6
 b. Understand the basics of different dosage forms, pharmaceutical incompatibilities
and pharmaceutical calculations
c. Understand the professional way of handling the prescription
d. Preparation of various conventional dosage forms

2. Content distribution as per the list of topics, time allotted for each topic, distribution for
‘Must know’, ‘Desirable to know’ and ‘Nice to know’ and the probable weightage.

The following table can also be a reference frame for continuous and formative assessment
of learning. If the curriculum management is scheduled as per the tabulation, there can be
clarity for both learners and teachers to take stock of the mastery achieved in each objective.
This will also help for professional excellence that goes beyond the examination process.

UNIT-I Hours: 10 Weightage: 16 Marks

Learning Topics
content
a. Historical background and development of profession of pharmacy
distribution
b. Dosage forms.
c. Prescription.
Must know Historical background and development of profession of pharmacy:
History of profession of Pharmacy in India in relation to pharmacy education,
industry and organization, Pharmacy as a career, Pharmacopoeias:
Dosage forms: Introduction to dosage forms, classification and definitions
Prescription: Definition, Parts of prescription, handling of Prescription and
Errors in prescription.
Posology: Definition, Factors affecting posology. Pediatric dose calculations
based on age, body weight and body surface area
Desirable to Introduction to IP, BP, USP and Extra Pharmacopoeia
know
Nice to know Marketed examples of dosage forms and Novel dosage forms.
Telepharmacy

UNIT-II Hours: 10 Weightage: 18 Marks

Learning Topics
content
a. Pharmaceutical calculations
distribution
b. Powders:
c. Liquid dosage forms:
Must know Pharmaceutical calculations: Calculations involving percentage solutions,
allegation, proof spirit and isotonic solutions based on freezing point and
molecular weight.
Powders: Definition, classification, advantages and disadvantages, Simple &
compound powders – official preparations, dusting powders, effervescent,
and hygroscopic powders, eutectic mixtures. Geometric dilutions.
Liquid dosage forms: Advantages and disadvantages of liquid dosage
forms. Excipients used in formulation of liquid dosage forms. Solubility
enhancement techniques
Desirable to Weights and measures – Imperial & Metric system
know Define proof spirit, isotonic solution
Definition of different powders with examples
Definition and Examples of excipients
Nice to know Marketed powder dosage forms
Grades of excipients

7
UNIT-III Hours: 10 Weightage: 26 Marks
Learning Topics
content
a. Monophasic liquids
distribution
b. Biphasic liquids
c. Suspensions
d. Emulsions
Must know Monophasic liquids: Preparations of Gargles, Mouthwashes, Throat Paint,
Eardrops, Nasal drops, Enemas, Syrups, Elixirs, Liniments and Lotions.
Biphasic liquids:
Suspensions: advantages and disadvantages, classifications, Preparation of
suspensions; Flocculated and Deflocculated suspension & stability problems
and methods to overcome.
Emulsions: Test for the identification of type of Emulsion, Methods of
preparation & stability problems and methods to overcome.
Desirable to Definitions with formula
know Definition Classification of suspending agents
Advantages, disadvantages and classification of suspensions
Definition Classification of emulsifying agents
Nice to know Marketed monophasic liquid dosage forms.
Marketed suspensions.
Marketed emulsions.

UNIT-IV Hours: 8 Weightage: 17 Marks

Learning Topics
content
a. Suppositories:
distribution
b. Pharmaceutical incompatibilities
Must know Suppositories: Definition, types, advantages and disadvantages, types of
bases Pharmaceutical, methods of preparations. Evaluation of
suppositories.
Incompatibilities: Definition, classification, chemical and therapeutic
incompatibilities with examples.

Desirable to Displacement values and its calculations

know Physical incompatibility with examples
Nice to know Examples of Marketed suppositories
Drug interactions in prescriptions

UNIT-V Hours: 7 Weightage: 12 Marks

Learning Topics
content
Semisolid dosage forms
distribution
Must know Semisolid dosage forms: Definitions, classification, mechanisms and factors
influencing dermal penetration of drugs. Preparation of ointments, pastes,
creams and gels. Evaluation of semi solid dosages forms.

Desirable to Excipients used in semi solid dosage forms

know
Nice to know Examples of marketed semisolid dosage forms

8
 3. Blueprint of question paper, for each QP. This shows the weightage given to each
chapter in the summative assessment. This improves the content validity by distributing
the assessment of learners in the competencies that are represented by learning
objectives under each chapter. State the number of QPs for the subject.

BLUE PRINT OF MODEL QUESTION PAPER

BP103T-Pharmaceutics-I
TIME: 3 HOURS MAX. MARKS: 75

Unit No Must know Desirable to know Weightage

Hours

LE SE SA LE SE SA of marks
(10X3) (5X7) (2X6) (10X0) (5X2) (2X4)
Unit-I 10 1 1 - - - 1 17
Unit-II 10 - 2 2 - - 2 18
Unit-III 10 1 2 2 - 1 1 26
Unit-IV 08 1 1 - - 1 1 22
Unit-V 07 - 2 1 - - 12
Total 45 30 35 10 - 10 10 95
75 20 95

______________________________

9
BP104T. Pharmaceutical Inorganic Chemistry

1. Departmental objectives (what the learners will be able to perform after completing
the subject):
B. Learning Objectives:

Upon completion of this course the student should be able to:

i. Know the sources of impurities and methods to determine the impurities in

inorganic drugs and pharmaceuticals

ii.Understand the medicinal and pharmaceutical importance of inorganic

compounds.

2. Content distribution as per the list of topics, time allotted for each topic, distribution for
‘Must know’, ‘Desirable to know’ and ‘Nice to know’ and the probable weightage.

The following table can also be a reference frame for continuous and formative assessment
of learning. If the curriculum management is scheduled as per the tabulation, there can be
clarity for both learners and teachers to take stock of the mastery achieved in each objective.
This will also help for professional excellence that goes beyond the examination process.

UNIT-I Hours: 10 Weightage: 26 Marks

Learning Topics
content
Impurities in Pharmaceutical substances
distribution
Must know Sources and types of impurities, principle and procedure involved in limit
test, definition- limit test, modified limit test.
Desirable to History of Pharmacopeia, Indian pharmacopeia, Importance of limit test
know effects of impurities in drug substances
Nice to know Test for purity, permissible limits of impurities in pharmaceuticals,

UNIT-II Hours: 10 Weightage: 19 Marks

Learning Topics
content
a. Acids, Bases and Buffers
distribution
b. Major intra and extracellular electrolyte
c. Dental products
Must know a. Definition and types of buffers, Buffers equations, mechanism behind
maintaining the pH by buffer solutions, acidic and basic buffer solution
preparations, isotonicity measurement of buffer solutions.
b. Functions of major physiological ions, combinations of electrolytes
replacement therapy (ORS), physiological acid base balance,
preparation, properties and uses of sodium chlorides, potassium chloride,
calcium gluconate, ORS. Assay of sodium chloride and calcium
gluconate.
c. Role of fluorides in treatment of dental caries, dentifrices, desensitizing
agent, dental cement, method of preparation , properties uses of sodium

10
 fluoride, calcium carbonate, Zinc eugenol cement
Desirable to 1.Buffer capacity, stability
know 2.Classification of physiological ions, their daily requirements, disease
occurs due the deficiency of ions,
3. Classification of dental products, abrasive properties of dentifrices
Nice to know 1.Buffers in pharmaceutical systems
2. Respiratory and circulatory system helps in maintaining the pH in
various b body compartments
3. Mouthwash, types of dental disorders

UNIT-III Hours: 10 Weightage: 24 Marks

Learning Topics
content
a. Gastrointestinal agents
distribution
b. Antimicrobials
Must know a. Classification of gastrointestinal agents, gastrointestinal disorders,
acidifiers, antacids and ideal properties of antacids, combination of
antacids, cathartics, gastrointestinal protective agents, synonym,
molecular formula, method of preparation, properties, uses, storage
conditions of ammonium chlorides, HCl, sodium bicarbonate,
aluminium hydroxide, magnesium hydroxide mixture, magnesium
sulphate, sodium orthophosphate, kaolin, bentonite.
b. Definition, classification and mechanism of action of antimicrobials,
synonym, molecular formula, method of preparation, properties, uses,
storage conditions of potassium permanganate, boric acid, hydrogen
peroxide, chlorinated lime, iodine and its preparations,
Assay of hydrogen peroxide, chlorinated lime
Desirable to a. Mechanism of saline cathartics, mechanism of gastrointestinal
know protective agents, classification of laxatives
b. Definition and examples of antiseptic, disinfectant, bacteriostatic,
bactericidal
Nice to know 1. Preparation of HCl, peptic ulcer, doses and adverse effects of antacids
2. Importance of iodine ,

UNIT-IV Hours: 8 Weightage: 19 Marks

Learning Topics
content
a) Expectorants, b) Emetics, c) Haematinics, d) Poison and
distribution
antidotes, e) Astringent
Must know a. Definition and classification of expectorants, synonym, molecular
formula, method of preparation, properties, uses, storage conditions of
Ammonium chloride, potassium iodide, Assay of ammonium chloride.
b. Definition of emetics , synonym, molecular formula, method of
preparation, properties, uses, storage conditions of copper sulphate,
sodium potassium tartarate. Assay of copper sulphate,
c. Definition of Haematinics , synonym, molecular formula, method of
preparation, properties, uses, storage conditions of ferrous sulphate,
ferrous gluconate
d. Definition and classification of antidotes , synonym, molecular formula,
method of preparation, properties, uses, storage conditions of sodium
thiosulphate, activated charcoal sodium nitrite, Assay of sodium
thiosulpahte.

11
 e. Definition of astringents , synonym, molecular formula, method of
preparation, properties, uses, storage conditions of zinc sulphate,
potash alum
Desirable to c. Mechanism of saline cathartics, mechanism of gastrointestinal
know protective agents, classification of laxatives
d. Definition and examples of antiseptic, disinfectant, bacteriostatic,
bactericidal
Nice to know Doses of expectorants, Doses of emetics, Doses and importance of
haemantinics, Poisoning effect of inorganic compounds, Importance of
Astringents

UNIT-V Hours: 7 Weightage: 07 Marks

Learning Topics
content
Radiopharmaceuticals
distribution
Must know Isotopes, properties of , β, γ, radiations, measurement of radio
activity, pharmaceutical applications storage conditions and
precautions of sodium iodide I131 and other important radioactive
substances
Desirable to Radio activity, half life
know
Nice to know Importance of radioactive substances in other field.

3. Blueprint of question paper, for each QP. This shows the weightage given to each
chapter in the summative assessment. This improves the content validity by distributing
the assessment of learners in the competencies that are represented by learning
objectives under each chapter. State the number of QPs for the subject.
BLUE PRINT OF MODEL QUESTION PAPER
BP104T. Pharmaceutical Inorganic Chemistry
TIME: 3 HOURS MAX. MARKS: 75

Unit No Must know Desirable to know Weightage

Hours

LE SE SA LE SE SA of marks
(10X3) (5X8) (2X6) (10X0) (5X2) (2X4)
Unit-I 10 1 1 2 - 1 1 26
Unit-II 10 1 1 2 - - 2 19
Unit-III 10 1 2 2 - - 1 24
Unit-IV 08 - 3 2 - - 1 19
Unit-V 07 - 1 1 - - 07
Total 45 30 40 18 - 5 10 95
88 15 95
___________________

BP105T: Communication kills

UNIT-I Hours: 7 Weightage: 15 Marks

Learning Topics
content
Communication skills
distribution
Must know  Importance of communication

12
  Classification of barriers
 To understand various perspectives
Desirable to  Methodologies of communication
know  History of barriers
Feelings or beliefs
Nice to know  Feedback, context
 World culture
 Cultural ethos

UNIT-II Hours: 7 Weightage: 15 Marks

Learning Topics
content
Elements of communication
distribution
Must know  Types of communication
 Types of communication styles
Desirable to  Looks and attitude
know  Capacity to assess the strength of the listeners
Nice to know  Etticacies, styles, clothing, protocol and gestures

UNIT-III Hours: 7 Weightage: 7 Marks

Learning Topics
content
Basic listening skills
distribution
Must know  Various basic listening skills
 Various aspects of effective writing
 Writing skills
Desirable to  Meditation techniques, consciousness
know  Hash tag communication
Nice to know  Sensitization and relaxation techniques
 Value addition with quotes and slogans
 Handwriting and signature analysis

UNIT-IV Hours: 5 Weightage: 7 Marks

Learning Topics
content
Interview skills
distribution
Must know  Purpose, Do’s and Don’ts
 Planning and structuring presentation delivery
Desirable to  Know your employer
know  Preparing interesting visual aids, etc
Nice to know  Concept of tele-interviews
 Knowledge of software skills, etc

UNIT-V Hours: 4 Weightage: 6 Marks

Learning Topics
content

13
distribution Interview skills

Must know  Purpose, Do’s and Don’ts

 Planning and structuring presentation delivery
Desirable to  Know your employer
know  Preparing interesting visual aids, etc
Nice to know  Concept of tele-interviews
 Knowledge of software skills, etc

3. Blueprint of question paper, for each QP. This shows the weightage given to each
chapter in the summative assessment. This improves the content validity by distributing the
assessment of learners in the competencies that are represented by learning objectives
under each chapter. State the number of QPs for the subject.

BLUE PRINT OF MODEL QUESTION PAPER

BP105T: Communication kills*
Unit (Hrs) Long Essays Short Essays Short Total Marks
Answers
Unit I (7 hrs) 10 5 - 15
Unit II (7 hrs) 10 5 - 15
Unit III (7 hrs) - 5 2 7
Unit IV (5 hrs) - 5 2 7
Unit V (4 hrs) - - 2+2+2 6
TOTAL 50
* Non University Examination (NUE)

14
 SEMESTER-II

BP 201T. Human Anatomy and Physiology-II

1. Departmental objectives (what the learners will be able to perform after completing the
subject):
A. Learning Objectives:

Upon completion of this course the student should be able to

a. Explain the gross morphology, structure and functions of various organs of the
human body.
b. Describe the various homeostatic mechanisms and their imbalances.
c. Identify the various tissues and organs of different systems of human body.
d. Perform the hematological tests like blood cell counts, haemoglobin
estimation, bleeding/clotting time etc and also record blood pressure, heart
rate, pulse and respiratory volume.
e. Appreciate coordinated working pattern of different organs of each system
f. 6. Appreciate the interlinked mechanisms in the maintenance of normal
functioning (homeostasis) of human body.

2. Content distribution as per the list of topics, time allotted for each topic, distribution for
‘Must know’, ‘Desirable to know’ and ‘Nice to know’ and the probable weightage.

The following table can also be a reference frame for continuous and formative
assessment of learning. If the curriculum management is scheduled as per the
tabulation, there can be clarity for both learners and teachers to take stock of the
mastery achieved in each objective. This will also help for professional excellence that
goes beyond the examination process.

UNIT-I Hours: 10 Weightage: 21 Marks

Learning Topics
content
Nervous System
distribution
Must know a. Organization of central nervous system, Structure and function of
cerebrum, cerebellum, brainstem.
b. Classification and properties of nerve fibre, Electro physiology,
c. Action potential-nerve impulse, receptors, synapse,
neurotransmitters
d. Spinal cord-gross structure, functions of afferent and efferent nerve
tracts and reflex activity.
Desirable to Structure and functions of neuron and neuroglia.
know Meninges, ventricles of brain, cerebro spinal fluid
Nice to know Types of neurotransmitters in CNS, definations of meningitis, encephalitis,
parkinsonism

15
UNIT-II Hours: 6 Weightage: 14 Marks
Learning Topics
content
distribution
Digestive system, Energetics
Must know Anatomy and physiology Salivary glands, stomach(acid production in
stomach, regulation of acid production through parasympathetic nervous
system), pancreas, liver, small intestine and large intestine.
Movements of small and large intestine, digestion and absorption of nutrients
in GIT.
Formation and role of ATP
Desirable to Disorders of GIT-gastritis, peptic ulcer, hypochlorhydria, hepatitis,
know constipation, diarrhoea, GERD, liver cirrhosis, anorexia, pancreatitis.
Creatinine phosphate and Basal metabolic rate(BMR).
Nice to know Fatty liver, insulin resistance

UNIT-III Hours: 10 Weightage: 22 Marks

Learning Topics
content
Respiratory system
distribution
Must know Anatomy of respiratory system with special reference to anatomy of lungs.
Mechanism of respiration, regulation of respiration
Desirable to Lung Volumes and capacities transport of respiratory gases, artificial
know respiration, and resuscitation methods
Nice to know Bombay blood group, formation of body fluids from blood

UNIT-IV Hours: 7 Weightage: 19 Marks

Learning Topics
content
Endocrine system
distribution
Must know Structure and functions of pituitary gland, thyroid gland, parathyroid gland,
adrenal gland, pancreas, pineal gland, thymus
Desirable to Classification of hormones, mechanism of hormone action,
know Disorders-acromegaly, cretinism, pheochromocytoma, diabetes incipidus,
diabetes mellitus, Addisons disease, cushing syndrome, gigantisim , dwarfism.
Myxedema, grave’s disease
Nice to know Hormone supplements

16
 UNIT-V Hours: 9 Weightage: 19 Marks
Learning Topics
content
Reproductive system
distribution
Introduction of Genetics
Must know a.Anatomy and physiology of male and female reproductive system,
physiology of menstruation,
b. Spermatogenesis, oogenesis, pregnancy and parturition
c.Chromosomes, genes and DNA, protein synthesis, genetic pattern of
inheritance
Desirable to sex hormones, fertilization
know
Nice to know Infertility, erectile dysfunction, PCOD

Blueprint of question paper, for each QP. This shows the weightage given to each chapter in
the summative assessment. This improves the content validity by distributing the
assessment of learners in the competencies that are represented by learning objectives
under each chapter.

BLUE PRINT OF MODEL QUESTION PAPER

BP 201T. Human Anatomy and Physiology-II

TIME: 3 HOURS MAX. MARKS: 75

Unit No Must know Desirable to know Weightage

Hours

LE SE SA LE SE SA of marks
(10X3) (5X8) (2X5) (10X0) (5X1) (2X5)
Unit-I 10 1 1 1 - - 2 21
Unit-II 10 2 1 - - 1 14
Unit-III 10 1 2 1 - - - 22
Unit-IV 08 1 1 1 - - 1 19
Unit-V 07 2 1 - 1 1 19
Total 45 30 40 10 - - -
80 15 95

__________________________

17
BP202T. Pharmaceutical Organic Chemistry –I

1. Departmental objectives (what the learners will be able to perform after completing
the subject):
A. Learning Objectives:

Upon completion of this course the student should be able to

a. write the structure, name and the type of isomerism of the organic compound

b. write the reaction, name the reaction and orientation of reactions

c. account for reactivity/stability of compounds,

d. identify/confirm the identification of organic compound

2. Content distribution as per the list of topics, time allotted for each topic, distribution for
‘Must know’, ‘Desirable to know’ and ‘Nice to know’ and the probable weightage.

The following table can also be a reference frame for continuous and formative
assessment of learning. If the curriculum management is scheduled as per the
tabulation, there can be clarity for both learners and teachers to take stock of the
mastery achieved in each objective. This will also help for professional excellence that
goes beyond the examination process.

UNIT-I Hours: 7 Weightage: 9 Marks

Learning Topics
content
Classification, nomenclature and isomerism
distribution
Must know  Classification of Organic compounds.
 Common and IUPAC systems of Nomenclature of Alkanes, alkenes,
dienes, alkynes, alcohols, aldehydes, ketones, ethers, alkyl halides,
amines, carboxylic acids, esters, acid chlorides, amides, and
cycloalkanes.
 Definition, Classification of Isomerism with examples.
Structural Isomerism
Desirable to -
know
Nice to know Chemical Bonds, Stereoisomerism with example

UNIT-II Hours: 10 Weightage: 24 Marks

18
Learning Topics
content
Alkanes, Alkenes and Conjugated dienes
distribution
Must know  General methods of preparation and reactions of Alkanes, Alkenes &
Conjugated dienes.
 SP2 and SP3 hybridization in Alkene and alkanes respectively.
 Halogenation of alkanes,
 E1 and E2 reactions – kinetics, order of reactivity of alkyl halides
 E1 verses E2 reactions, Factors affecting E1 and E2 reactions.
 Electrophilic addition reactions of alkenes, Markownikoff‘s orientation,
free radical addition reactions of alkenes, Anti Markownikoff‘s
orientation.
 Stability of conjugated dienes, electrophilic addition, free radical
addition reactions of conjugated dienes.
Desirable to  Uses of paraffins,
know  Ozonolysis,
 Stabilities of alkenes
 Saytzeffs orientation.
 Evidences for E1 verses E2 reactions,
 Rearrangement of carbocations
 Allylic rearrangement
 Diel-Alder reaction
Nice to know  Polarity and Dipole moment
 SP hybridization,
 Effect of Resonance on stability of alkenes and dienes
 Elimination reaction
 Cycloaddition reaction

UNIT-III Hours: 10 Weightage: 22 Marks

Learning Topics
content
Alkyl halides
distribution
Alcohols
Must know  SN1 and SN2 reactions - kinetics, order of reactivity of alkyl halides,
stereochemistry and stability, rearrangement of carbocations.
 SN1 versus SN2 reactions, Factors affecting SN1 and SN2 reactions
 Structure and uses of ethylchloride, Chloroform, trichloroethylene,
tetrachloroethylene, dichloromethane, tetrachloromethane and iodoform

 General methods of preparation and reactions of Alcohols

 Structure and uses of Ethyl alcohol, chlorobutanol, Cetosteryl alcohol,
Benzyl alcohol, Glycerol, Propylene glycol
Desirable to  General methods of preparation and reactions of Alkyl halide.
know  Qualitative tests of Ethyl alcohol, chlorobutanol, Cetosteryl alcohol,
Benzyl alcohol, Glycerol, Propylene glycol

Nice to know Substitution reaction, Optical Isomerism

Types of alcohols, Hydrogen bonding and its applications

19
UNIT-IV Hours: 10 Weightage: 24 Marks
Learning Topics
content
Carbonyl compounds (Aldehydes and ketones)
distribution
Must know  Nucleophilic addition, aldol condensation, Crossed Aldol condensation,
Cannizzaro reaction, Crossed Cannizzaro reaction, Benzoin condensation,
Perkin condensation
 General methods of preparation and reactions of Aldehydes and Ketones
Desirable to  Electromeric effect
know  Qualitative tests, Structure and uses of Formaldehyde, Paraldehyde,
Acetone, Chloral hydrate, Hexamine, Benzaldehyde, Vanilin,
Cinnamaldehyde
Nice to know Addition Reaction

UNIT-V Hours: 8 Weightage: 16 Marks

Learning Topics
content
Carboxylic acids
distribution
Aliphatic amines
Must know  General methods of preparation and reactions of Carboxylic acid
 Inductive effect
 Acidity of carboxylic acids, effect of substituents on acidity,
 Qualitative tests for carboxylic acids, amide and ester
 General methods of preparation and reactions of Aliphatic amines
 Basicity, effect of substituent on Basicity
Desirable to  Structure and Uses of Acetic acid, Lactic acid, Tartaric acid, Citric acid,
know Succinic acid. Oxalic acid, Salicylic acid, Benzoic acid, Benzyl benzoate,
Dimethyl phthalate, Methyl salicylate and Acetyl salicylic acid
 Qualitative test, Structure and uses of Ethanolamine, Ethylenediamine,
Amphetamine
Nice to know Theories of Acids and Bases

20
 BLUE PRINT OF MODEL QUESTION PAPER
BP202T. Pharmaceutical Organic Chemistry –I

TIME: 3 HOURS MAX. MARKS: 75

Unit No Must know Desirable to know Weightage

Hours

LE SE SA LE SE SA of marks
(10X3) (5X8) (2X5) (10X0) (5X1) (2X5)
Unit-I 7 -- 1 2 -- -- -- 09
Unit-II 10 1 2 -- -- -- 2 24
Unit-III 10 1 1 -- -- 1 1 22
Unit-IV 10 1 2 -- -- -- 2 24
Unit-V 8 -- 2 1 -- -- 2 16
Total 45 30 40 6 -- 5 12 95
76 19 95

___________________

BP203 T. Biochemistry

1. Departmental objectives (what the learners will be able to perform after completing
the subject):
B. Learning Objectives:

Upon completion of this course the student should be able to

a. Understand the catalytic role of enzymes, importance of enzyme inhibitors in

design of new drugs, therapeutic and diagnostic applications of enzymes.

b. Understand the metabolism of nutrient molecules in physiological and

pathological conditions.

c. Understand the genetic organization of mammalian genome and functions of

DNA in the synthesis of RNAs and proteins.

2. Content distribution as per the list of topics, time allotted for each topic, distribution for
‘Must know’, ‘Desirable to know’ and ‘Nice to know’ and the probable weightage.

The following table can also be a reference frame for continuous and formative
assessment of learning. If the curriculum management is scheduled as per the
tabulation, there can be clarity for both learners and teachers to take stock of the
mastery achieved in each objective. This will also help for professional excellence that
goes beyond the examination process.

UNIT-I Hours: 10 Weightage: 24 Marks

21
Learning Topics
content
Carbohydrate metabolism
distribution
Biological oxidation
Must know  Glycolysis – Pathway , energetics and significance
 Citric acid cycle- Pathway , energetics and significance
 HMP shunt and its significance; Glucose-6-Phosphate dehydrogenase
(G6PD) deficiency
 Glycogen metabolism Pathway s and glycogen storage diseases
(GSD)
 Gluconeogenesis- Pathway and its significance
 Electron transport chain (ETC) and its mechanism.
 Oxidative phosphorylation & its mechanism and substrate level
 phosphorylation
Desirable to  Hormonal regulation of blood glucose level
know  Inhibitors ETC and oxidative phosphory lation/Uncouplers
Nice to know  Types of Diabetes mellitus

UNIT-II Hours: 10 Weightage: 24 Marks

Learning Topics
content
Lipid metabolism
distribution
Amino acid metabolism
Must know  β-Oxidation of saturated fatty acid (Palmitic acid)
 Formation and utilization of ketone bodies; ketoacidosis
 De novo synthesis of fatty acids (Palmitic acid)
 Disorders of lipid metabolism:
 Hypercholesterolemia, atherosclerosis, fatty liver and obesity.
 General reactions of amino acid metabolism: Transamination,
 deamination & decarboxylation, urea cycle and its disorders
 Catabolism of phenylalanine and tyrosine and their metabolic disorders
 (Phenylketonuria, Albinism, alkeptonuria, tyrosinemia)
Desirable to  Biological significance of cholesterol and conversion of cholesterol into
know Bile acids, steroidal hormones and Vitamin D
 Synthesis and significance of biological substances; 5-HT, melatonin,
dopamine, noradrenaline, adrenaline
Catabolism of heme; hyperbilirubinemia and jaundice
Nice to know  Types of jaundices and causes

UNIT-III Hours: 10 Weightage: 22 Marks

Learning Topics
content
Nucleic acid metabolism and genetic information transfer
distribution
Must know  Biosynthesis of purine and pyrimidine nucleotides
 Catabolism of purine nucleotides and Hyperuricemia and Gout disease
 Organization of mammalian genome
 Structure of DNA & RNA and their functions
 DNA replication (semi conservative model)
 Transcription or RNA synthesis
 Genetic code, Translation or Protein Synthesis and inhibitors
 Protein Synthesis and inhibitors
 Catabolism of phenylalanine and tyrosine and their metabolic disorders

22
  (Phenylketonuria, Albinism, alkeptonuria, tyrosinemia)
Desirable to --
know
Nice to know  Types of replication and mutation

UNIT-IV Hours: 8 Weightage: 9 Marks

Learning Topics
content
Biomolecules and Bioenergetics
distribution
Must know  Introduction, classification, chemical nature and biological role of
carbohydrate, lipids, nucleic acids, amino acids and proteins.
 Concept of free energy , endergonic and exergonic reaction,
 Energy rich compounds; classification; biological significances of ATP and
cyclic AMP
Desirable to Redox potential.
know Relationship between free energy , enthalpy and entropy
Nice to know  Standard free energy

UNIT-V Hours: 7 Weightage: 16 Marks

Learning Topics
content
Enzymes
distribution
Must know  Introduction, properties, nomenclature and IUB classification of
enzymes
 Enzyme kinetics (Michaelis plot, Line Weaver Burke plot)
 Regulation of enzymes: allosteric
 enzymes regulation
 Therapeutic and diagnostic applications of enzymes and isoenzymes
 Coenzymes –Structure and biochemical functions
Desirable to  Enzyme inhibitors with examples
know Enzyme induction and repression
Nice to know  Factors affecting enzyme activity

BLUE PRINT OF MODEL QUESTION PAPER

BP203 T. Biochemistry

TIME: 3 HOURS MAX. MARKS: 75

Unit No Must know Desirable to know Weightage

Hours

LE SE SA LE SE SA of marks
(10X3) (5X6) (2X8) (10X0) (5X1) (2X2)
Unit-I 10 1 1 2 - 1 - 24
Unit-II 10 1 1 2 - 1 - 24
Unit-III 10 1 2 1 - - - 22
Unit-IV 8 - 1 1 - - 1 09
Unit-V 7 - 1 2 - 1 1 16
Total 45 30 30 16 - 15 4
76 19 95
________________________

23
BP 204T.Pathophysiology

1. Departmental objectives (what the learners will be able to perform after completing
the subject):
A. Learning Objectives:

Upon completion of this course the student should be able to

1. Describe etiology and pathogenesis of the selected disease states

2. Name the signs and symptoms of diseases, and
3. Mention the complications of the diseases

3. Content distribution as per the list of topics, time allotted for each topic,
distribution for ‘Must know’, ‘Desirable to know’ and ‘Nice to know’ and the
probable weightage.

The following table can also be a reference frame for continuous and
formative assessment of learning. If the curriculum management is scheduled as per
the tabulation, there can be clarity for both learners and teachers to take stock of the
mastery achieved in each objective. This will also help for professional excellence
that goes beyond the examination process.

UNIT-I Hours: 10 Weightage: 17 Marks

Learning Topics
content Basic principles of Cell injury and Adaptation
distribution Basic mechanism involved in the process of inflammation and
repair
Must know  Causes of cellular injury, Pathogenesis (Cell membrane damage,
Mitochondrial damage, Ribosome damage, Nuclear damage)
 Introduction, Clinical signs of inflammation, Different types of
Inflammation
 Mechanism of Inflammation – Alteration in vascular permeability
and blood flow, migration of WBC‘s
 Mediators of inflammation
 Basic principles of wound healing in the skin, Pathophysiology of
Atherosclerosis
Desirable to  Morphology of cell injury – Adaptive changes (Atrophy,
know Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling,
Intra cellular accumulation, Calcification, Enzyme leakage
 Cell Death Acidosis &Alkalosis, Electrolyte imbalance
Nice to know  Introduction, Definitions, Homeostasis, Components and Types of
feedback systems

24
UNIT-II Hours: 10 Weightage: 15 Marks
Learning Topics
content Cardiovascular System
distribution Respiratory system
Renal system
Must know  Hypertension, congestive heart failure.
 Ischemic heart disease (angina, myocardial infarction, atherosclerosis
and arteriosclerosis).
 Asthma, Chronic obstructive airways diseases
Desirable to Acute and chronic renal failure
know
Nice to know -

UNIT-III Hours: 10 Weightage: 17 Marks

Learning Topics
content Haematological Diseases
distribution Endocrine system
Nervous system
Gastrointestinal system
Must know  Iron deficiency, megaloblastic anaemia (Vit B12 and folic acid), sickle
cell anaemia, thalasemia, hereditary acquired anaemia, haemophilia
 Diabetes, thyroid diseases, disorders of sex hormones
 Epilepsy, Parkinson‘s disease, stroke, psychiatric disorders: depression,
schizophrenia and Alzheimer‘s disease
 Peptic Ulcer
Desirable to ------
know
Nice to know -------

UNIT-IV Hours: 8 Weightage: 7 Marks

Learning Topics
content Disease of bones and joints
distribution Principles of cancer
Nervous system
Gastrointestinal system
Must know  Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F)
alcoholic liver disease
 Classification, etiology and pathogenesis of cancer
Desirable to Rheumatoid arthritis, osteoporosis and gout
know
Nice to know -------

UNIT-V Hours: 7 Weightage: 7 Marks

Learning Topics
content Infectious diseases
distribution

25
 Sexually transmitted diseases
Must know  Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F)
alcoholic liver disease
 Classification, etiology and pathogenesis of cancer
Desirable to Meningitis, Typhoid, Leprosy, Tuberculosis Urinary tract infections
know
Nice to know Syphilis, Gonorrhoea

BLUE PRINT OF MODEL QUESTION PAPER

BP 204T.Pathophysiology

TIME: 3 HOURS MAX. MARKS: 75

Unit No Must know Desirable to know Weightage

Hours

LE SE SA LE SE SA of marks
(10X3) (5X7) (2X10) (10X0) (5X0) (2X5)
Unit-I 10 1 1 3 - - - 21
Unit-II 10 1 1 1 - - 2 21
Unit-III 10 1 2 1 - - - 22
Unit-IV 8 - 2 2 - - 1 16
Unit-V 7 - 1 3 - - 2 15
Total 45 30 35 20 - - 10
85 10 95

______________________

26