Requisition No
: 240080072 Date : 16/10/2024
Patient Name : DANIEL ENDURANCE
Referred By
: LOKOJA Batch Number :
Collection Time
: 09/10/2024 Age : Ad Sex : Male
HBV QUANTITATIVE
Description Result Unit Normal Range
HBV-DNA QUANTIFICATION 749 IU/mL
Clinical SPECIMEN TYPE: BLOOD
Note NO CLINICAL DATA SPPLIED
SEND TO HOSPITAL
Pathology *****NOTE: THE HBV VIRAL LOAD CAN BE EXPRESSED AS LOG 3.17 comment
CONVERSION FACTOR: IU/mL TO COPIES/mL MULTIPLY BY 5.8
Clinical Utility: The viral load provides the direct and reliable estimate of the level of HBV
replication. Quantitation of HBV DNA level is important as it serves to be a prognostic
marker of HBV infection. It is used for establishing baseline levels in patients before
initiation of the therapy and for monitoring therapeutic response and disease progression.
A sudden rise in the viral load may indicate emergence of resistant strains during the
therapy.
Interpretation: HBV viral load is expressed as IU/ml The lower limit of detection of this
assay is 20.0 IU/mL. Values below 20.0 IU/ml does not exclude the possibility of an
infection. It may reflect a viral load below the detection limit of the assay. An increase or
decrease of more than threefold may be considered clinically significant. Follow up viral
load values below the detectable limit may indicate resolution of the infection after
therapy. Reappearance or increasing viral load may indicate relapse or resistance to the
therapy. All viral load results should be interpreted in conjunction with the clinical history,
clinical status of the patient and other diagnostic parameters. Recommendations: Viral
load is a monitoring test and hence should not be used for screening or diagnostic purpose.
Wide variations in viral load have been observed due to following reasons:
a) Use of different technologies/ platforms for follow up testing. Hence, it is recommended
to monitor patients using same technology.
b) Nonadherence to specimen collection protocol. Hence, it is recommended to immediately
freeze the serum/EDTA plasma after collection and separation.
Limitations: PCR is a highly sensitive technique common reasons for paradoxical results
are contamination during specimen collection, selection of inappropriate specimens and
inherent PCR inhibitors in the specimen. and inherent PCR inhi bitors in the
specimen.
H=High, L=Low
***** END OF REPORT *****
