DEPARTMENT OF PHARMACOLOGY & THERAPEUTICS,

CHANDKA MEDICAL COLLEGE, SMMBMU, LARKANA.

BCQs pool for MS/ MD Course.

1.A patient is brought to the emergency 6. All of the following are therapeutic
department shortly after taking a massive indications of prostaglandins except:
dose of levothyroxine in an apparent a). Gastric cytoprotection.
suicide attempt. Which of the following b). Termination of pregnancy.
drugs should be administered for prompt c). Treatment of peptic ulcer.
control of toxic effect that will most likely d). Asthma.
lead to death if not correctly managed? e). Maintenance of patency of ductus arteriosus.

a). Lugol’s iodine. 7. A 30 year young depressed smoker

wants to quit smoking, which one of the
b). Carbimazole
c). Propranolol following drug is suitable to benefit his
d). Propylthiouracil depression and help to avoid smoking:
a). Sertraline.
e). Radioiactive iodine.
b). Nefazodone.
2.A middle age lady came to psychiatric c). Paroxetine.
clinic, complaining of habits of washing d). Bupropion.
her hands repeatedly without any e). Trazodone.
justification. Which one of the following is
drug of choice to relieve her symptoms: 8. Polyuria, polydipsia, tremors and
edema are common adverse effects of one
a). Amoxapine. of the following drug used for the
b). Phenelzine. treatment of manic depressive disorder:
c). Clomipramine. a). Carbamazepine.
d). Desipramine. b). Valproic acid.
e). Fluoxetine. c). Oxcarbazepine.
3.Which of the following intravenous d). Lithium.
anesthetic agent possesses anti emetic e). Clozapine.
properties: 9. Which one of the following ergot
a). Thiopentone sodium. alkaloid is used to control postpartum
b). Propofol. hemorrhage:
c). Ketamine. a). Ergotamine.
d). Diazepam. b). Ergonovine.
e). Etomidate. c). Lysergic – acid diethylamide (LSD).
4.A 40 year patient comes to family d). Methysergide.
physician with drug-induced e). Bromocriptine.
hyperuricemia. Clinician’s goal is to 10. Which of the following NSAIDs is
inhibit uric acid synthesis. Which of the relatively non – selective cox – inhibitor:
following drugs would be appropriate a). Celocoxib.
choice: b). Rofecoxib.
a). Allopurinol c). Piroxicam.
b). Aspirin d). Valdecoxib.
c). Celecoxib e). Meloxicam.
d). Hydrocortisone.
e). Probenecid 11. A 51 year old woman with symptoms of
5.A patient admitted in emergency having major depression also has narrow angle
fracture of radius & ulna with severe pain glaucoma, which of the following anti-
and restlessness. Best choice to calm down depressant should be avoided in this
and relieve pain is: patient:
a). Naproxen. a). Amitriptyline
b). Propoxyphene. b). Sertraline
c). Pentazocine. c). Bupropion
d). Diclofenac. d). Mirtazepine
e). Ketoprofen. e). Fluvoxamine
12. Which one of the following anti – 18. A Cardiologist prescribed a drug to a
diabetic agents, delays the digestion of hypertensive patient. One hour after
carbohydrate: taking initial dose patient became
a). Miglitol . extensively hypotensive and went into
b). Tolbutamide. syncope, the causative agent could be:
c). Glipizide. a). Tamsulosin.
d). Repaglinide. b). Propranolol.
e). Pioglitazone. c). Prazocin.
d).Metoprolol.
13. Indirectly acting cholinmimetic that e). Terazocin.
can cross the blood brain barrier easily is:
a). Ambenonium. 19. Preferred beta blocker in asthmatic
b). Neostigmine. patient is:
c). Physostigmine. a). Pindolol.
d). Pyridostigmine. b). Propranolol.
e). Edrophonium. c). Atenolol.
d). Labetalol.
14. Which of the following selective alpha e). Carvedilol.
receptor agonist is used orally for
autonomic insufficiency and postural 20. Drugs that bind to physiological
hypotension: receptors and their effects mimic the
a). Methoxamine. regulatory effects of the endogenous
b).Mephenteramine. signaling compounds are called:
c). Metaraminol. a). Antagonists.
d). Midodrine. b). Agonists.
e). Oxymetazoline. c). Reversible antagonists.
d). Partial agonists.
15. A Physician wants to prescribe a drug e). Irreversible antagonists.
which could relieve spasm of GIT smooth
muscle without affecting Hcl secretion. 21. Which one of the following Alpha
The choice will be: receptor antagonists is irreversibly acting
a). Cyclopentolate. drug used in pheochromocytoma:
b). Ipratropium. a). Prazosin.
c). Atropine. b). Doxazosin.
d). Pirenzepine. c). Phenoxybenzamine.
e). Darifencin. d). Phentolamine.
e). Yohimbine.

16. Which of the following parameter is 22. Which of the following mydriatic is
useful to define the overall exposure of a used for retinal examination without
person to a drug during the dosing
producing cycloplegia:
interval:
a). AUC (area under curve). a) Ephedrine
b). Half life. b) Epinepherine
c). Clearance. c) Pilocarpine
d). C max. d) Isoproterenol
e). E max. e) Phenylephrine
17. Which of the following drug is used to 23. A drug with a half life of 6 hours is
treat malignant hyperthermia induced by administered by continuous IV infusion, if
variety of drugs : the drug follows first order kinetic how
a). Atracurium. long will it take for the drug to reach
b). Tizanidine.. steady state concentration:.
c). Succinycholine. a).40 hours
d). Dantrolene. b).90 hours
e). Vecuronium. c).18 hours
d).24 hours
e). 30 hours
24. A 27 years old Farmer was brought to also suffers from recurrent peptic ulcer
emergency department with sign and and is currently on antiulcer treatment
symptoms of bronchoconstriction, meiosis, since last two weeks. Which of the
lacrimation, salivation, urination, and following drug must be avoided in this
CNS excitation. He was engaged in patient:
spraying pesticide on agricultural crop 2 a). Celecoxib.
days back. Which of the following drug b). Valdecoxib.
would be administered as initial treatment c). Meloxicam.
to give symptomatic relief: d). Etodolac.
a). Atropine. e). Piroxicam.
b). Propranolol.
c) Pralidoxime. 30. Which one of the following drugs used
d). Neostigmine. for the treatment of gout is xanthine
e). Trimethaphan. oxidase inhibitor:
a). Colchicine.
25. The delicate balance between the b). Sulfinpyrazone.
desired effect and unwanted toxicity of c). Probenecid.
drug referred to as its: d). Febuxostat.
a). Potency. e). Tolmetin.
b). Intrinsic activity.
c). Therapeutic index. 31. Which of the following disease
d). Bioavailability. modifying antirheumatic drug acts
e). Efficacy. through blocking Alpha tumor necrotic
factor:
26. Topical application of timolol to the eye a).Methotrexate.
would be expected to induce which of the b). Cyclosporin.
following effect: c). Sulfasalazine.
a). Miosis. d). Infliximab.
b). Mydriasis. e). Azathioprine.
c). Decreased formation of aquous
homour. 32. One of the following drugs, is used for
d). Increased outflow of aqueous humour. prophylaxis of migraine:
e). Increased blood flow to optic nerve. a). Ergotamine.
b). Sumatriptan.
27. Activation of prejunctional α – 2 c). Verapamil.
receptors on sympathetic nerve ending is d). Aspirin.
associated with: e). Naproxen.
a). Activation of adenylcyclase.
b). Decrease in cAMP. 33. A factory worker suffering from
c). Increase in IP3. anxiety disorder, attends his physician for
d). Inhibition of protein kinase. treatment of his problem. Physician wants
e). Opening of Na+/ K+ cation channels. to prescribe an anxiolytic agents with least
sedative effect. Which one of the following
28. A full term baby at birth suffered from drug would be the most appropriate
cyanosis, breathlessness and tachycardia. choice:
Cardiac opinion was sought and the baby a). Zeleplon.
was detected with atresia of pulmonary b). Zolpidem.
artery. Which of the following drug would c). Buspirone.
be an appropriate choice to relieve d). Ramelteon.
symptoms up till the corrective surgery: e). Eszopiclone.
a). Indomethacin.
b). Ibuprofen.
c). Alprostadil.
d). Carboprost.
e). Acetaminophen.

34. A young girl visits her family physician

with complaint of intractable hiccup for
29. A 35 year lady suffering from arthritic last two days, which one of the following
pain attends family physician’s clinic. She
drug would be appropriate choice to
benefit the problem:
a). Clozapine.
b). Haloperidol.
c). Chlorpromazine.
d). Pimozide.
e). Thioridazine.
35. A 45 year old man suffered from road
traffic accident and complained of severe
pain. Heavy doses of morphine were given
within 24 hours to relieve pain. After last
injection of morphine patient developed
pin point pupil and became unconscious.
Which of the following drug would be
appropriate to relieve the symptomatology
that developed after last injection of
morphine :
a). Nalorphine.
b). Flumazenil.
c). Benztropine.
d). Neostigmine.
e). Naloxone.

(Prof. Dr. Riaz Ahmed Shaikh)

Chairman,
Department of Pharmacology
Chandka Medical College,
SMBBMU, Larkana.

Dated: 22 – 11 – 2013.
 KEY
Q. No: Answer. Q. No: Answer.

1 c 19 c
2 e 20 b
3 b 21 c
4 a 22 e
5 c 23 e
6 d 24 a
7 d 25 c
8 d 26 c
9 b 27 b
10 c 28 c
11 a 29 e
12 a 30 d
13 c 31 d
14 d 32 c
15 c 33 c
16 a 34 c
17 d 35 e
18 c