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PRIMARY DATABASE SECONDARY DATABASE
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It is the first hand information of It is derived from information
experimental data from scientists gathered in primary database.
and researchers.
Data not edited or validated. Data is manually annotated.
Raw and original submission of Data has highest quality and it is
data. double checked.
Made available for public It is mainly focused on proteins.
annotation .
Eg: NCBI, EMBL etc. Eg: CATH, SCOPE etc.
ttHf.,rt 1Fifi/£ HRff' ·• ··
G tobnl Sequence A ITg n m~nt
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tho cna.e 1equcallCo [ooa to cild 111lgnmm) sin11\DJ1ry bcn-.·ocn th~ M,Qi riacrw:ncoD.
A gtlbal al.gnrnEnt con.ans aJJ latte.rs mm both A loca! ~ ~ nt Bliigrs a S:Ullstri ri!] nf lhe q ~
~equerce en a sub:SUing DI tile tar gen ~lEfl ~ -
II two rmquC?flC,il!j hnvti Qp?f7a~lmrnd)' ltic so.ml! AfYIJ f'l,f() sequrrnoou Clln be ioaill~ nlilg,nca b5 locnl
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o f rie51 af I.ti£ s.EqUence rEgElllS.
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compamg tnni1olOQ't1Us gel'E'!i like mmpnnng U sed lnr lm111g our mnsi!Jl\ied l)nttems ., Dl"-JA
two genes w rth same function pn h.rlllilll vs. 51-eQl.ifrCes □r conserved CHllTiain!i or mo'tJfs 11 tvm
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> Na'dlcmo.11-Wunsch Global Allun ~, ) EMBOSS Wll.1er
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