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1. A known patient of bronchial asthma was started on treatment with an anti- glaucoma
drug. During the course of treatment, asthma worsened. Which drug is likely responsible for
these symptoms?
a. Timolol
b. Brimonidine
c. Latanoprost
d. Pilocarpine
2. Which of the following correctly describes the Phenomenon of vasomotor reversal of
Dale?
a. Repeated administration of ephedrine decreases its effect on blood pressure
b. High dose of acetylcholine after pre-treatment with atropine produces increase in
blood pressure and heart rate
c. A patient pre-treated with Phentolamine develops severe hypotension on
administration of adrenaline
d. Increase in pulse pressure is produced by intravenous administration of isoprenaline
3. One asthmatic female admitted in hospital with 22 weeks pregnancy having BP 158/100,
Best drug to control her BP is:
a. Nifedipine
b. Alpha methyl dopa
c. Labetalol
d. Atenolol
4. Modafinil used as an adjunct in the treatment of all of the below conditions except-
a. OSA (obstructive sleep apnoea)
b. ADHD (attention deficit hyperactive disorder)
c. Shift work disorder
d. Narcolepsy
5. Preganglionic sympathetic and parasympathetic fibers release ____, postganglionic
parasympathetic fibers release ____ (in muscarinic receptors), and postganglionic
sympathetic fibers release ____ (in sweat glands).
a. ACh; ACh; ACh
b. ACh; NE; ACh
c. NE; ACh; NE
d. NE; NE; Ach
6. Which is a correct match for anti-glaucoma medications:
a. Timolol- Increases aqueous production
b. Netarsudil- Increases trabecular outflow
c. Brimonidine-Increases uveoscleral outflow
d. Latanoprost- Increases trabecular outflow
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7. A 70 year old man, Ramkumar comes to you and is having irritative symptoms due to
retention of urine, diagnosed to be having benign hypertrophy of prostate. The drug which
provides relief symptoms in this patient is?
A. Bethenechol
B. Imipramine
C. Tamsulosin
D. Dutasteride
8. Which antihypertensive is not safe in elderly patients because of risk of precipitation of
asthma, bradycardia & heart failure:
a. Indapamide
b. Amlodipine
c. Propranolol
d. Enalapril
9. Propranolol is not useful in-
a. Tremor
b. HOCM
c. Angina
d. Partial AV-block
10. All are true about Neostigmine except-
a. Tertiary ammonium compound
b. Reversal effect of depolarising muscle relaxants
c. Use in cobra bite treatment
d. Reduce post op paralytic ileus
11 Atropine is used in all except-
a. Glaucoma
b. Mydriatic
c. Cyclopegic
d. Preanaesthetic
12. Longest acting beta-blocker is-
a. Nebivolol
b. Nadolol
c. Esmolol
d. Sotalol
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13. Which of the following diuretics acts primarily by inhibiting the sodium-potassium-chloride
cotransporter in the thick ascending limb of the loop of Henle?
a) Hydrochlorothiazide
b) Furosemide
c) Spironolactone
d) Amiloride
14. Which diuretic is increasing survival rate in patients of congestive heart failure?
a) Spironolactone
b) Furosemide
c) Hydrochlorothiazide
d) Amiloride
15. Beta blocker should not be given to a patient on verapamil because of risk of?
a. Bronchospasm
b. Conduction block
c. Tachyarrhythmia
d. HTN
16. Angiotensin receptor blocker having PPAR-gamma agonist activity is
a. Telmisartan
b. Irbesartan
c. Losartan
d. Candesartan
17. Antihypertensive causing positive comb’s test is
a. Methyl dopa
b. Clonidine
c. Captopril
d. Sodium nitroprusside
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18. Which of the following drug used as an antihypertensives, can cause sedation
a. Amlodipine
b. Telmisartan
c. Clonidine
d. Fenoldapam
19. All of the following drugs use during CPR except
a. Atropine
b. Epinephrine
c. Verapamil
d. Vasopressin
20. First orally acting direct renin inhibitor is
a. Captopril
b. Aliskiren
c. Kallikarin
d. Ramipril
21. Calcium sensitizing agent is
a. Levosimendan
b. Teriparatide
c. Strontium
d. Ivabradine
22. An old female patient on antihypertensive suddenly develops skin rashes with swelling of
tongue, lips & eyes causing her difficulty in breathing. Which drug can cause this dangerous side
effect
a. Hydrochlorthiazide
b. Captopril
c. Propranolol
d. Amlodipine
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23. Following drugs having significant drug interaction with digoxin except
a. Amlodipine
b. Hydrochlorthiazide
c. Quinidine
d. Cholestyramine
24. Which of the following drug can increase survival in CHF patients
a. Losartan
b. Amrinone
c. Furosemide
d. Digoxin
25. All of the following are actions of β – blockers while used in CHF except
a. Prevention of cardiac arrhythmia
b. Prevention of remodeling of myocardium
c. Antagonism of vasoconstriction due to sympathetic over activity
d. Decrease in mortality
26. Which of the following drug decreases plasma rennin level
a. Atenolol
b. Enalapril
c. Losartan
d. Hydralazine
27. Ramipril is contraindicated in all of the following except
a. Single kidney
b. Hyperkalemia
c. B/L RAS
d. Diabetic nephropathy
28. Which of the following drug is used for reversal of reflex cerebral vasospasm in subarachnoid
haemorrhage patients
a. Rofecoxib
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b. Diltiazem
c. Nimodipine
d. Nifedipine
29. First dose hypotension is a common side effect of which antihypertensives
a. ACE inhibitors
b. α – blockers
c. β – blockers
d. Nitrates
30. Sodium nitroprusside acts by activation of
a. Cyclic AMP
b. K+ channel
c. Guanylate cyclase
d. Ca+2 channel
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