MANONMANIAM SUNDARANAR UNIVERSITY, TIRUNELVELI – 627 012

DEPARTMENT OF PHARMACEUTICAL CHEMISTRY

(UNIVERSITY DEPARTMENT)

CURRICULUM AND SYLLABUS FOR

DIPLOMA IN PHARMACY (D. Pharm)

(With effective from the Academic year, 2018-2019 onwards)
 DIPLOMA IN PHARMACY (D. Pharm)

ACADEMIC REGULATIONS

1. Duration of the course

The duration of the course shall be for two academic years, with each academic year spread
over a period of not less than 180 working days in addition to 500 hours practical training
spread over a period of not less than 3 months.

2. Eligibility for Admission

No candidate shall be admitted to D. Pharm Part-I unless he/she has passed any of the
following examinations in all the optional subjects and compulsory subjects (Physics,
Chemistry and Biology / Mathematics / Biotechnology / Computer Science):

(i) Intermediate examination in Science;

(ii) The first year of the three year degree course in Science;

(iii) 10+2 examination (Academic stream) in Science;

(iv) Pre-degree examination;

(v) Any other qualification approved by the Pharmacy Council of India as equivalent
to any of the above examination.

Admissions of candidates to the Diploma in Pharmacy Part-I shall be made as per the rules
/ directions of the central admission authority / State Government.

3. Scheme of study and examination

3.1 The medium of instruction and examination shall be English.

3.2 Candidates for the D. Pharm course shall be instructed and examined as per the
Teaching and Examination Scheme and Course Content of respective year.

4. Eligibility for appearing at the examination

4.1 No candidate shall be allowed to appear in any examination unless he / she has attended
75% of the classes held in each theory and practical separately in each subject at an
academic institution.

4.2 A candidate who has been admitted to D. Pharm Part I and has attended a regular course of
study in an academic institution shall be eligible to appear at D.Pharm Part I examination of
the University.

4.3 A candidate who has been promoted to D.Pharm Part II as per the provisions for conditions
of passing and has attended a regular course of study in an academic institution shall be
eligible to appear at D.Pharm Part II examination of the University.
5. Sessional examination (Internal assessment)

The sessional marks in each theory and practical subject shall be awarded out of a
maximum of 20 marks in the following manner:

5.1 Theory sessional (20 marks)

At least two written tests of 20 marks each in every theory subject shall be conducted by the
academic institution at regular interval during each academic year. The average of best two
performances shall be taken into consideration for computation of theory sessional marks.
Duration of each written test shall be of one hour.

5.2 Practical sessional (20 marks)

The sessional marks in practical shall be computed on the basis of the performance in the
practical test (10 marks) and day-to-day assessment (10 marks) in the practical class.

5.2.1 Practical test (10 marks)

At least two practical tests of 10 marks each in every subject shall be conducted by the
academic institution at regular interval during each academic year. The average of best two
performances shall be taken into consideration for computation of practical test marks.
Duration of each practical test shall be same as prescribed for practical class in respective
practical subject. Each practical test may be conducted in different parts, viz., synopsis /
spotting, exercise / experiment and viva-voce etc.

5.2.2 Day-to-day evaluation of practical work (10 marks)

The concerned teacher shall make the evaluation of day-to-day practical work in the
laboratory on the basis of the performance of the candidate and maintenance of practical
record.

5.3 The regular record of marks of sessional examination conducted at an academic institution
shall be maintained for each student and must be submitted to the University before the
commencement of University examination.

5.4 A candidate failing in any of the subjects shall have a chance to improve his / her sessional
marks both in theory and practical by appearing in one additional sessional examination. The
aggregate of best two performances from all the sessionals shall form the basis of
calculating the average for computation of improved sessional marks. Marks for day-to-day
assessment in the practicals cannot be improved unless a candidate attends a regular
course of study again.

6. University examination

6.1 There shall be a main and a supplementary University examination in a year as per the
Teaching and Examination Scheme and Course Content for D.Pharm Part I and D.Pharm
Part II. Main examination shall be held in the month of March/April or on such dates as may
be fixed by the University. Supplementary examination shall be conducted within 30 days of
the declaration of results or on such dates as may be fixed by the University.
6.2 University examination in each theory subject shall be of three hours duration. There shall be
7 questions carrying equal marks, out of which 5 questions shall have to be attempted.

6.3 University examination in each practical subject shall be of prescribed hours duration and
shall comprise of synopsis / spotting, exercise / experiment and viva-voce etc. The head of
the institution shall send the awards to the University, on or before the prescribed date.

7. Practical training

7.1 Period and other conditions of practical training

7.1.1 After having appeared in Part-II examination of Diploma in Pharmacy, a candidate shall be
eligible to undergo practical training in one or more of the following institutions, namely:

(i) Hospitals / Dispensaries run by Central / State Governments /Municipal Corporations /

Central Government Health Scheme and Employees State Insurance Scheme.

(ii) A Pharmacy, Chemist and Druggist licensed under the Drugs and Cosmetics Rules,
1945 made under the Drugs and Cosmetics Act, 1940 (23 of 1940).

7.1.2 The institutions referred in sub-regulation (1) shall be eligible to impart training subject to the
condition that the number of student pharmacists that may be taken in any hospital,
pharmacy, chemist and druggist licensed under the Drugs and Cosmetics Rules, 1945 made
under the Drugs and Cosmetics Act, 1940 shall not exceed two where there is one
registered pharmacist engaged in the work in which the student pharmacist is undergoing
practical training, where there is more than one registered pharmacist similarly engaged, the
number shall not exceed one for each additional such registered pharmacist.

7.1.3 Hospital and Dispensary other than those specified in sub-regulation (1) for the purpose of
giving practical training shall have to be recognized by Pharmacy Council of India on fulfilling
the conditions specified in Appendix-D of the Education Regulations 1991 of Pharmacy
Council of India.

7.1.4 In the course of practical training, the trainees shall have exposure to:

(i) Working knowledge of keeping of records required by various acts concerning the
profession of pharmacy and

(ii) Practical experience in

(a) the manipulation of pharmaceutical apparatus in common use;

(b) the reading, translation and copying of prescription including checking of doses;
(c) the dispensing of prescriptions illustrating the commoner methods of
administering medicaments;
(d) the storage of drugs and medical preparations.

7.1.5 The practical training shall be not less than 500 hours spread over a period of not less than
3 months provided that not less than 250 hours are devoted to actual dispensing of
prescriptions.
7.2 Procedure to be followed prior to commencing of the training

7.2.1 The head of the academic training institution, shall supply application in triplicate in „Practical
Training Contract form for qualification as a Pharmacist‟ to candidate eligible to undertake
the said practical training. The contract form shall be as specified in Appendix-E to
Education Regulations 1991 of Pharmacy Council of India.

7.2.2 The head of an academic institution shall fill section I of the Contract Form. The trainee shall
fill section II of the said Contract Form and the Head of the institution agreeing to impart the
training (hereinafter referred to as the Apprentice Master) shall fill section III of the said
Contract Form.

7.2.3 It shall be the responsibility of the trainee to ensure that one copy (hereinafter referred to as
the first copy of the Contract Form) so filled is submitted to head of the academic training
institution and the other two copies (hereinafter referred to as the second copy and the third
copy) shall be filed with apprentice master (if he so desires) or with the trainee pending
completion of the training.

7.3 Certificate of completion of practical training

On satisfactory completion of the practical training, the apprentice master shall fill Section IV
of the second copy and third copy of Contract Form and cause it to be sent to the head of
the academic institution who shall suitably enter in the first copy of the entries from the
second copy and third copy and shall fill Section V of the three copies of Contract Form and
thereafter handover both the second copy and the third copy to the trainee.

This, if completed in all respect, shall be regarded as a certificate of having successfully

completed the practical training.

8. Conditions of passing

8.1 No candidate shall be declared as having passed in a subject unless he / she has secured
40% of the maximum marks in the University and sessional examination marks put together
in each theory and practical subject. Each theory and practical shall be considered as
separate subject.

8.2 A candidate who has failed in more than two subjects in D.Pharm Part I examination shall
not be allowed to pursue course for D.Pharm Part II. Such candidate will be allowed to
appear as an ex-student in the University examination of subsequent batch of D.Pharm. Part
I in the failing subjects.

8.3 A candidate who has failed in not more than two subjects in D.Pharm Part I examination
shall be allowed to appear in the supplementary examination of D.Pharm Part I in the failing
subjects. Candidates failing in any subject in the supplementary examination will be allowed
to appear as an ex-student in the University examination of subsequent batch of D.Pharm.
Part I in the failing subjects.

8.4 A candidate who has passed in all the subjects of D.Pharm Part I shall be promoted to
D.Pharm. Part II.

8.5 A candidate who has failed in more than two subjects in D.Pharm Part II examination shall
 be allowed to appear as an ex-student in the University examination of subsequent batch of
D.Pharm Part II in the failing subjects.

8.6 A candidate who has failed in not more than two subjects in D.Pharm Part II examination
shall be allowed to appear in the supplementary examination of D.Pharm Part II in the failing
subjects. Candidates failing in any subject in the supplementary examination shall be
allowed to appear as an ex-student in the University examination of subsequent batch of
D.Pharm Part II in the failing subjects.

8.7 A candidate who is unable to appear at any examination in any subject(s) due to any reason
whatsoever shall be considered as having failed in that subject(s).

8.8 In no case, a candidate, who has not passed finally after 6 academic years from the year of
admission, shall be allowed to continue the course.

9. Award of Diploma, Division and Rank

9.1 After passing the D.Pharm Part II examination and on satisfactory completion of the practical
training, a candidate shall be awarded certificate of Diploma in Pharmacy.

9.2 The actual marks (and not the passing marks) as obtained by a candidate in a
supplementary / attempt examination shall be counted for award of division.

9.3 The division to a successful candidate shall be awarded on the basis of aggregate of marks
obtained by him / her in D.Pharm Part I and D.Pharm Part II examinations regardless of the
number of attempts, as shown below:

Percentage of marks Division

75% or above Honors

60% or above First division

50% or above Second division

40% or above Pass

9.4 Rank and university gold medal shall be conferred to those candidates who have passed the
whole examination in first attempt (without any grace).
 TEACHING AND EXAMINATION SCHEME

D.Pharm Part I

Paper No. Subject Teaching Univ. Marks

hrs. per exam.
week hrs.
Sessi Univ. Total
onal Exam

D.Ph. 101T Pharmaceutics-I, Theory 3 3 20 80 100

D.Ph. 102P Pharmaceutics-I, Practical 4 3 20 80 100
D.Ph. 103T Pharmaceutical Chemistry-I, Theory 3 3 20 80 100
D.Ph. 104P Pharmaceutical Chemistry-I, Practical 3 3 20 80 100
D.Ph. 105T Pharmacognosy, Theory 3 3 20 80 100
D.Ph. 106P Pharmacognosy, Practical 3 3 20 80 100
D.Ph. 107T Biochemistry & Clinical Pathology, Theory 2 3 20 80 100
D.Ph. 108P Biochemistry & Clinical Pathology, Practical 3 3 20 80 100
D.Ph. 109T Human Anatomy & Physiology, Theory 3 3 20 80 100
D.Ph. 110P Human Anatomy & Physiology, Practical 2 3 20 80 100
D.Ph. 111T Health Education & Community Pharmacy, 2 3 20 80 100
Theory
Total 31 220 880 1100

D.Pharm Part II

Paper No. Subject Teaching Univ. Marks

hrs. per exam.
week hrs.
Sessi Univ. Total
onal Exam

D.Ph. 201T Pharmaceutics-II, Theory 3 3 20 80 100

D.Ph. 202P Pharmaceutics-II, Practical 4 3 20 80 100
D.Ph. 203T Pharmaceutical Chemistry-II, Theory 4 3 20 80 100
D.Ph. 204P Pharmaceutical Chemistry-II, Practical 3 3 20 80 100
D.Ph. 205T Pharmacology & Toxicology, Theory 3 3 20 80 100
D.Ph. 206P Pharmacology & Toxicology, Practical 2 3 20 80 100
D.Ph. 207T Pharmaceutical Jurisprudence, Theory 2 3 20 80 100
D.Ph. 208T Drug Store and Business Management, 3 3 20 80 100
Theory
D.Ph. 209T Hospital & Clinical Pharmacy, Theory 3 3 20 80 100
D.Ph. 210P Hospital & Clinical Pharmacy, Practical 2 3 20 80 100
Total 29 200 800 1000
 Course content

D.Pharm Part I

D.Ph. 101T Pharmaceutics-I, Theory 75 Hrs

Unit-I

1. Introduction to different dosage forms, their classification with examples—their relative

applications. Familiarization with new drug delivery systems.
2. Introduction to Pharmacopoeias with special reference to the Indian Pharmacopoeia.
3. Size reduction—objectives and factors affecting size reduction, methods of size reduction.
Study of hammer mill, ball mill, fluid energy mill and disintegrator.
4. Size separation—size separation by sifting. Official standards for powders. Sedimentation
methods of size separation. Construction and working of cyclone separator.

Unit-II

5. Metrology—system of weights and measures. Calculations including conversion from one to

another system. Percentage calculations and adjustment of products. Use of alligation
method in calculations. Isotonic solutions.
6. Mixing and homogenization—liquid mixing and powder mixing. Mixing of semisolids. Study of
silverson mixer homogensier, planetary mixer; agitated powder mixer; triple roller mill;
propeller mixer, colloid mill and hand homogenizer, double cone mixer.
7. Packaging of pharmaceuticals—desirable features of a container-types of containers. Study
of glass and plastics as materials for containers and rubber as a material for closure-their
merits and demerits. Introduction to aerosol packaging.

Unit-III

8. Extraction and galenicals—(a) Study of percolation and maceration and their modification,
continuous hot extraction—applications in the preparation of tinctures and extracts. (b)
Introduction to ayurvedic dosage forms.
9. Clarification and filtration—theory of filtration, filter media; filter aids and selection of filters.
Study of the following filtration equipments—filter press, sintered filters, filter candles,
metafilter.
10. Heat processes—evaporation-definition, factors affecting evaporation—study of evaporating
still and evaporating pan.
11. Introduction to drying processes—study of tray dryers, fluidized bed dryer, vacuum dryer and
freeze dryer.

Unit-IV

12. Distillation—simple distillation and fractional distillation, steam distillation and vacuum
distillation. Study of vacuum still, preparation of purified water I.P. and water for injection I.P.
Construction and working of the still used for the same.
13. Sterilization—concept of sterilization and its differences from disinfection—thermal resistance
of micro-organisms. Detailed study of the following sterilization processes.
(i) Sterilization with moist heat,
(ii) Dry heat sterilization,
(iii) Sterilization by radiation,
 (iv) Sterilization by filtration and
(v) Gaseous sterilization.

Aseptic techniques, applications of sterilization processes in hospitals particularly with

reference to surgical dressings and intravenous fluids. Precautions for safe and effective
handling of sterilization equipment.

Unit-V

14. Study of immunological products like sera, vaccines, toxoids and their preparations.
15. Processing of tablets—definition; different type of compressed tablets and their properties.
Processes involved in the production of tablets; tablets excipients; defects in tablets;
evaluation of tablets; physical standards including disintegration and dissolution. Tablet
coating-sugar coating; film coating, enteric coating and microencapsulation (tablet coating
may be dealt in an elementary manner).
16. Processing of capsules—hard and soft gelatin capsules; different sizes of capsules; filling of
capsules; handling and storage of capsules. Special applications of capsules.

D.Ph. 102P Pharmaceutics-I, Practical 100 Hrs

Preparations (minimum number stated against each of the following categories illustrating
different techniques involved)
1. Aromatic water 3
2. Solutions 4
3. Spirits 2
4. Tinctures 4
5. Extracts 2
6. Creams 2
7. Cosmetic preparations 3
8. Capsules 2
9. Tablets 2
10. Preparations involving sterilization 2
Ophthalmic
11. preparations 2
12. Preparations involving aseptic techniques 2

REFERENCE BOOKS (LATEST EDITION)

Pharmaceutics – I (D.Ph. 101T & D.Ph. 102P)

1. Remington‟s Pharmaceutical Sciences.
2. The Extra Pharmacopoeia-Martindale.
D.Ph. 103T Pharmaceutical Chemistry-I, Theory 75 Hrs

1. General discussion on the following inorganic compounds including important physical and
chemical properties, medicinal and pharmaceutical uses, storage conditions and chemical
incompatibility.

Unit-I

(A) Acids, bases and buffers—boric acid*, calcium hydroxide, hydrochloric acid, strong
ammonium hydroxide, sodium hydroxide and official buffers.
(B) Gastrointestinal agents—
(i) Acidifying agents—dilute hydrochloric acid.
(ii) Antacids—sodium bicarbonate, aluminium hydroxide gel, aluminium phosphate,
calcium carbonate, magnesium carbonate, magnesium trisilicate, magnesium oxide,
combinations of antacid preparations.

(iii) Protectives and adsorbents—bismuth subcarbonate and kaolin.

(iv) Saline cathartics—sodium potassium tartrate and magnesium sulphate.

Unit-II

(C) Antioxidants—hypophosphorous acids, sulphur dioxide, sodium bisulphite, sodium

metabisulphite, sodium thiosulphate, nitrogen and sodium nitrite.
(D) Topical agents—
(i) Protectives—talc, zinc oxide, calamine, zinc stearate, titanium dioxide, silicone
polymers.
(ii) Antimicrobials and astringents—hydrogen peroxide*, potassium permanganate,
chlorinated lime, Iodine, solutions of iodine, povidone iodine, boric acid, borax, silver
nitrate, mild silver protein, mercury, yellow mercuric oxide, ammoniated mercury.
(iii) Sulphur and its compounds—sublimed sulphur, precipitated sulphur, selenium sulfide.
(iv) Astringents—alum and zinc sulphate.

Unit-III

(E) Dental products—sodium fluoride, stannous fluoride, calcium carbonate, sodium

metaphosphate, dicalcium phosphate, strontium chloride, zinc chloride.
(F) Inhalants—oxygen, carbon dioxide, nitrous oxide.
(G) Respiratory stimulants—ammonium carbonate.
(H) Expectorants and emetics—ammonium chloride*, potassium iodide, antimony potassium
tartrate.
(I) Antidotes—sodium nitrite.
2. Major intra and extracellular electrolytes—
(A) Electrolytes used for replacement therapy—sodium chloride and its preparations,
potassium chloride and its preparations.
(B) Physiological acid-base balance and electrolytes used—sodium acetate, potassium
acetate, sodium bicarbonate injection, sodium citrate, potassium citrate, sodium lactate
injection, ammonium chloride and its injection.
(C) Combination of oral electrolyte powders and solutions.
 Unit-IV

3. Inorganic official compounds of iron, iodine and calcium; ferrous sulfate and calcium
gluconate.
4. Radio pharmaceuticals and contrast media-radioactivity-alpha; beta and gamma radiations,
biological effects of radiations, measurement of radioactivity, G.M. counter; radio isotopes—
their uses, storage and precautions with special reference to the official preparations. Radio
opaque contrast media—barium sulfate.
5. Identification tests for cations and anions as per Indian Pharmacopoeia.

Unit-V

6. Quality control of drugs and pharmaceuticals—importance of quality control, significant

errors, methods used for quality control, sources of impurities in pharmaceuticals, limit tests
for arsenic, chlorides, sulfates, iron and heavy metals.

D.Ph. 104P Pharmaceutical Chemistry-I, Practical 75 Hrs

1. Identification tests for inorganic compounds particularly drugs and pharmaceuticals.

2. Limit test for chlorides, sulfates, arsenic, iron and heavy metals.
3. Assay of inorganic pharmaceutical (involving each of the following methods) compounds
marked with (*) under theory.
(a) Acid-base titrations (at least 3)
(b) Redox titrations (one each of permanganometry and iodimetry)
(c) Precipitation titrations (at least 2)
(d) Complexometric titrations (calcium and magnesium).

REFERENCE BOOKS (LATEST EDITION)

Pharmaceutical Chemistry - I (D.Ph. 103T & D.Ph. 104P)

1. Pharmacopoeia of India, Govt. of India, Ministry of Health, Delhi.
2. Beckett A.H. and Stenlake J.B., Practical Pharmaceutical Chemistry, Part-I, The Athlene Press
University of London.
3. Chatten L.G., Pharmaceutical Chemistry, Vol. I & II, Marsccel Dekker, New York.
4. L. M. Arthadon, Benlty, T. B. of Pharmaceutical Chemistry, British Press.
5. Block J., Roche E.B., Sonie T.O., Wilson C.O., Inorganic Pharmaceutical chemistry, Lea &
Febiger, Philadelphia, PA.
6. Atherden L.M, Bentley and Driver‟s Text Book of Pharmaceutical Chemistry, Oxford
University Press, London.
7. Jeffery G.H., Bassett J., Mendham J., Denney R.C., Volgel‟s Text book of quantitative chemical
analysis, E.L.B.S. London.
8. Disher L. A., Modern Inorganic Pharmaceutical Chemistry
. D.Ph. 105T Pharmacognosy, Theory 75 Hrs

Unit-I

1. Definition, history and scope of pharmacognosy including indigenous system of medicine.

2. Various systems of classification of drugs of natural origin.
3. Adulteration and drug evaluation; significance of pharmacopoeial standards.

Unit-II

4. Brief outline of occurrence, distribution, outline of isolation, identification tests, therapeutic

effects and pharmaceutical applications of alkaloids, terpenoids, glycosides, volatile oils,
tannins and resins.
5. Occurrence, distribution, organoleptic evaluation, chemical constituents including tests
wherever applicable and therapeutic efficacy of following categories of drugs.
(a) Laxatives—aloes, rhubarb, castor oil, ispaghula, senna.
(b) Cardiotonics—digitalis, arjuna.
(c) Carminatives & G.I. regulators—umbelliferous fruits-coriander, fennel, ajowan,
cardamom, ginger, black pepper, asafoetida, nutmeg, cinnamon, clove.

Unit-III

(d) Astringents—catechu.
(e) Drugs acting on nervous systems—hyoscyamus, belladonna, aconite, ashwagandha,
ephedra, opium, cannabis, nux vomica.
(f) Anithypertensives—rauwolfia.
(g) Antitussives—vasaka, tolu balsam, tulsi.
(h) Antirheumatics—guggal, colchicum.
(i) Antitumour—vinca.
(j) Antileprotics—chaulmoogra oil.
(k) Antidiabetics—pterocarpus, gymnema sylvestro.
(l) Diuretics—gokhru, punarnava.
(m) Antidysenterics—ipecacuanha.
(n) Antiseptics and disinfectants—benzoin, myrrh, neem, curcuma.
(o) Antimalarials—cinchona.

Unit-IV

(p) Oxytocics—ergot.
(q) Vitamins—shark liver oil and amla.
(r) Enzymes—papaya, diastase, yeast.
(s) Perfumes and flavouring agents—peppermint oil, lemon oil, orange oil, lemon grass oil,
sandalwood.
(t) Pharmaceutical aids—honey, arachis oil, starch, kaolin, pectin, olive oil, lanolin, beeswax,
acacia, tragacanth, sodium alginate, agar, guar gum, gelatin.
(u) Miscellaneous—liquorice, garlic, picrohiza, dioscorea, linseed, shatavari, shankpushpi,
pyrethrum, tobacco.
 Unit-V

6. Collection and preparation of crude drugs from the market as exemplified by ergot, opium,
rauwolfia, digitalis, senna.
7. Study of source, preparation and identification of fibres used in sutures and surgical
dressings—cotton, silk, wool and regenerated fibres.
8. Gross anatomical studies of senna, datura, cinnamon, cinchona, fennel, clove, ginger,
nuxvomica and ipecacuanha.

D.Ph. 106P Pharmacognosy, Practical 75 Hrs

1. Identification of drugs by morphological characters.

2. Physical and chemical tests for evaluation of drugs wherever applicable.
3. Gross anatomical studies (t.s.) of the following drugs : senna, datura, cinnamon, cinchona,
coriander, fennel, clove, ginger, nuxvomica, ipecacuanha.
4. Identification of fibers and surgical dressings.

REFERENCE BOOKS (LATEST EDITION)

Pharmacognosy (D.Ph. 105T & D.Ph. 106P)

1. Kokate C. K., Practical Pharmacognosy, Vallabh Prakashan, Delhi.
2. Kokate C. K., Purohit A. P. and Gokhale S. B., Pharmacognosy , Nirali Prakashan, Pune.
3. Tylor V. E., Brady L. R. and Robbers J. E., Pharmacognosy 1981, Learned Febiger,
Philadelphe, U. S. A.
4. Trease G. E. Pharmacognosy and Evans W. C., Baillers Tindall, London.
5. Wallis T. E. Pharmacognosy, J. A. Churchill.
 D.Ph. 107T Biochemistry and Clinical Pathology, Theory 50 Hrs

Unit-I

1. Introduction to biochemistry.
2. Brief chemistry and role of carbohydrates, classification, qualitative tests. Diseases related to
carbohydrate metabolism.
Unit-II

3. Brief chemistry and role of proteins, polypeptides and amino acids, classification, qualitative
tests, biological value, deficiency diseases.
4. Role of minerals and water in life processes.
Unit-III

5. Brief chemistry and role of lipids, classification, qualitative tests. Diseases related to lipid
metabolism.
Unit-IV

6. Brief chemistry and role of vitamins and coenzymes.

7. Enzymes—brief concept of enzymatic action and factors affecting it, therapeutic and
pharmaceutical importance.
Unit-V

8. Brief concept of normal and abnormal metabolism of proteins, carbohydrates and lipids.
9. Introduction to pathology of blood and urine.
(a)Lymphocytes and platelets, their role in health and disease.
(b)Erythrocytes, abnormal cells and their significance.
(c) Abnormal constituents of urine and their significance in diseases.

D.Ph. 108P Biochemistry and Clinical Pathology, Practical 75 Hrs

1. Detection and identification of proteins, amino acids, carbohydrates and lipids.

2. Analysis of normal and abnormal constituents of blood and urine (glucose, urea, creatine,
creatinine, cholesterol, alkaline phosphatase, acid phosphatase, bilirubin, SGPT, SGOT,
calcium, diastase, lipase).
3. Examination of sputum and faeces (microscopic & staining).
4. Practice in injecting drugs by intramuscular, subcutaneous and intravenous routes,
withdrawal of blood samples.

REFERENCE BOOKS (LATEST EDITION)

Biochemistry and Clinical Pathology (D.Ph. 107T & D.Ph. 108P)

1. Lehninger A. L., Principles of Biochemistry, CBS Publishers and Distributors, New Delhi.
2. Stryer L., Biochemistry, W H Freeman and Company, San Francisco.
3. A.V.S.S. Rama Rao, Text book of Biochemistry.
4. Conn E. E. and Stumpf P. K., Outlines of Biochemistry, John Wiley and Sons, New York.
5. Harrow B. and Mazur A., Textbook of Biochemistry, W. B. Saunders Co., Philadelphia.
6. Jayraman J., Laboratory Manual in Biochemistry, Wiley Eastern Limited, New Delhi.
7. Martin D. W., Mays P. A. and Redwell V. M., Harpers Biochemistry, Lange Medical Publications.
8. Mussay R. K., Granner D. K., Mayous P. A. and Rodwell Harpers Biochemistry, Prentice-Hall
International, Inc.
9. Plumer D. T., An Introduction to Practical Biochemistry, Tata MacGraw Hill, New Delhi.
 D.Ph. 109T Human Anatomy and Physiology, Theory 75 Hrs

Unit-I

1. Scope of anatomy and physiology, definition of various terms used in anatomy.

2. Structure of cell, function of its components with special reference to mitochondria and
microsomes.
3. Elementary tissues of the body, i.e. epithelial tissue, muscular tissue, connective tissue and
nervous tissue.
4. Structure and function of skeleton, classification of joints and their function, joint disorders.

Unit-II

5. Composition of blood, functions of blood elements, blood group and coagulation of blood,
brief information regarding disorders of blood.
6. Name and functions of lymph glands.
7. Structure and functions of various parts of the heart, arterial and venous system with special
reference to the names and positions of main arteries and veins, blood pressure and its
recording, brief information about cardiovascular disorders.

Unit-III

8. Various parts of respiratory system and their functions. Physiology of respiration.

9. Various parts of urinary system and their functions, structure and functions of kidney.
Physiology of urine
formation. Pathophysiology of renal diseases and oedema.

10. Reproductive system—physiology and anatomy of reproductive system.

Unit-IV

11. Structure of skeletal muscle. Physiology of muscle contraction, names, positions,

attachments and functions of various skeletal muscles. Physiology of neuromuscular junction.
12. Various parts of central nervous system, brain and its parts, functions and reflex action.
Anatomy and physiology of autonomic nervous system.
13. Elementary knowledge of structure and functions of the organs of taste, smell, ear, eye and
skin. Physiology of pain.

Unit-V

14. Digestive system—names of various parts of digestive system and their functions. Structure
and functions of liver, physiology of digestion and absorption.
15. Endocrine glands and hormones. Locations of glands, their hormones and functions—
pituitary, thyroid, adrenal and pancreas.
 D.Ph. 110P Human Anatomy and Physiology, Practical 50 Hrs

1. Study of the human skeleton.

2. Study with the help of charts and models, of the following system and organs:
(a) Digestive system (b) Respiratory system
(c) Cardiovascular system (d) Urinary system
(e) Reproductive system (f) Nervous system
(g) Eye (h) Ear
3. Microscopic examination of ephithelial tissue, cardiac muscle, smooth muscle, skeletal
muscle. Connective tissue and nervous tissues.
4. Examination of blood films for TLC, DLC and malarial parasite.
5. Determination of clotting time of blood, erythrocyte sedimentation rate and haemoglobin value.
6. Recording of body temperature, pulse, heart rate, blood pressure and ECG.

REFERENCE BOOKS (LATEST EDITION)

Human Anatomy and Physiology (D.Ph. 109T & D.Ph. 110P)

1. Derashari and Gandhi; Human Anatomy and physiology; B.S. Shah Prakashan.
2. C.C. Chatterjee; Human Physiology; Medical Alied Agency, Calcutta.
3. Goyal, Bhatt and Kumar; Basics of Health Education and Community Pharmacy; B.S. Shah
Prakashan.
4. Warwick & Williman Longman; Gray's Anatomy.
5. Sahana's Text Book of Anatomy.
6. Willium and Wilkins, Baltimore Best and Taylor's Physiological Basis of Medical Practice.
7. Difore Lea SH and Febiger, Atlas of Normal Histology, Philadephia.
8. Ganong WF, Review of Medical Physiology, Prentice Hall International.
9. Chourasia B.D.; Human Anatomy, Regional and Applied. Part I, II & III; CBS Publishers and
Distributor, New Delhi.
10. Gyuton A.C., Half J.E.;Text Book of Medical Physiology; WB Sannders Company.
11. Subhash Shaliya; Human Physiology; CBS Publishers and Distributors.
12. Keel C.A., Neil E and Joels N.; Samson Wright's Applied Physiology; Oxford University Press.
13. MC Naught A.B. and Callander R, Churchill Livingstone; Illustrated Physiology.
14. Ranade V.G.; Text Book of Practical Physiology; Pune Vidyarthi Griha Prakashan, Pune.
15. Tortora G.J. and Anagnodokos N.P.; Principles for Anatomy and Physiology; Harper and Row
Publishers N.Y.
16. Vander A.J. Shermati J.H. and Luciano D.S.; Human Physiology; Tata Mcgraw Hill Publishing
Co. New Delhi.
17. Goyal R.K.; A Text Book of Experimental Physiology; B.S. Shah Prakashan.
 D.Ph. 111T Health Education and Community Pharmacy, Theory 50 Hrs

Unit-I

1. Concept of health—definition of physical health, mental health, social health, spiritual health,
determinants of health, indicators of health, concept of disease, natural history of diseases,
the disease agents, concept of prevention of diseases.

2. Environment and health—sources of water supply, water pollution, purification of water,

health and air, noise, light—solid waste disposal and control-medical entomology, arthropod
borne diseases and their control, rodents, animals and diseases.

Unit-II

3. First aid—emergency treatment in shock, snake bite, burns, poisoning, heart disease,
fractures and resuscitation methods. Elements of minor surgery and dressings.
4. Fundamental principles of microbiology—classification of microbes, isolation, staining
techniques of organisms of common diseases.

Unit-III

5. Non-communicable diseases—causative agents, prevention, care and control. Cancer,

diabetes, blindness, cardiovascular diseases.
6. Communicable disease—causative agents, modes of transmission and prevention.
(a) Respiratory infections—chicken pox, measles, influenza, diptheria, whooping cough and
tuberculosis.
(b) Intestinal infections—poliomyelitis, hepatitis, cholera, typhoid, food poisoning, hookworm
infection.
(c) Arthropod borne infections—plague, malaria, filariasis.
(d) Surface infections—rabies, trachoma, tetanus, leprosy.
(e) Sexually transmitted diseases—syphilis, gonorrhoea, AIDS.

Unit-IV

7. Nutrition and health—classification of foods, requirements, diseases induced due to

deficiency of proteins, vitamins and minerals—treatment and prevention.
8. Demography and family planning—demography cycle, fertility, family planning, contraceptive
methods, behavioural methods, natural family planning methods, chemical methods,
mechanical methods, hormonal contraceptives, population problem of India.

Unit-V

9. Epidemiology—scope, methods, uses, dynamics of disease transmission, immunity and

immunisation, immunological products and their dose schedule. Principles of disease control
and prevention, hospital acquired infection, prevention and control. Disinfection, types of
disinfection procedures, for faeces, urine, sputum, room linen, dead bodies and instruments.

REFERENCE BOOKS (LATEST EDITION)

Health Education and Community Pharmacy (D.Ph. 111T)
1. N.S. Parmar; Health Education and Community Pharmacy; CBS Publishers
 D.Pharm Part II

D.Ph. 201T Pharmaceutics-II, Theory 75 Hrs

Unit-I

1. Dispensing Pharmacy:
(i) Prescriptions: Reading and understanding of prescription; latin terms commonly used
(detailed study is not necessary), modern methods of prescribing, adoption of metric
system, calculations involved in dispensing.

(ii) Incompatibilities in prescriptions: Study of various types of incompatibilities—physical,

chemical and therapeutic.
(iii) Posology: Dose and dosage of drugs, factors influencing dose, calculations of doses on
the basis of age, sex and surface area, veterinary doses.

Unit-II

2. Dispensed Medications:

(Note: A detailed study of the following dispensed medication is necessary. Methods of

preparation with theoretical and practical aspects, use of appropriate containers and
closures, special labeling requirements and storage conditions should be highlighted).
(i) Powders: Types of powders, advantages and disadvantages of powders, granules,
cachets and tablet triturates. Preparation of different types of powders encountered in
prescriptions. Weighing methods, possible errors in weighing, minimum weighable
amount and weighing of a material below the minimum weighable amount, geometric
dilution and proper usage and care of dispensing balance.
(ii) Liquid oral dosage forms:
(a) Monophasic—theoretical aspects including commonly used vehicles, essential
adjuvants like
stabilizers, colourants and flavours, with examples.
Review of the following monophasic liquids with details of formulation and practical
methods.

Liquids for internal Liquids for external administration

administration or used on mucous membranes
Mixtures and concentrates, Gargles
Syrups Mouth washes
Throat paints
Elixirs Douches
Ear drops
Nasal drops & sprays
Liniments
Lotions

Unit-III

(b) Biphasic liquid dosage forms:

• Suspensions (elementary study)—suspensions containing diffusible solids and
liquids and their preparations. Study of the adjuvants used like thickening agents,
 wetting agents, their necessity and quantity to be incorporated. Suspensions of
precipitate forming liquids like tinctures, their preparations and stability.
Suspensions produced by chemical reaction. An introduction to flocculated / non-
flocculated suspension system.

• Emulsions—types of emulsions, identification of emulsion system, formulation of

emulsions, selection of emulsifying agents. Instabilities in emulsions. Preservation
of emulsions.
(iii) Dental and cosmetic preparations:

Introduction to dentifrices, facial cosmetics, deodorants, antiperspirants, shampoos, hair

dressings and hair removers.

Unit-IV

(iv) Semi-solid dosage forms:

(a) Ointments—types of ointments, classification and selection of dermatological

vehicles. Preparation and stability of ointments by the following processes: (i)
trituration (ii) fusion (iii) chemical reaction (iv) emulsification.

(b) Pastes—differences between ointments and pastes, bases of pastes, preparation of

pastes and their preservation.
(c) Jellies—an introduction to the different types of jellies and their preparation.
(d) An elementary study of poultice.
(e) Suppositories and passaries—their relative merits and demerits, types of
suppositories, suppository bases, classification, properties. Preparation and packing
of suppositories. Use of suppositories for drug absorption.
Unit-V

(v) Sterile dosage forms:

(a) Parenteral dosage forms—definition, general requirements for parenteral dosage
forms, types of parenteral formulations, vehicles, adjuvants, processing, personnel,
facilities and quality control. Preparation of intravenous fluids and admixtures—total
parenteral nutrition, dialysis fluids.
(b) Sterility testing, particulate matter monitoring, faulty seal packaging.
(c) Ophthalmic products—study of essential characteristics of different ophthalmic
preparations. Formulation additives, special precautions in handling and storage of
ophthalmic products.
 D.Ph. 202P Pharmaceutics-II, Practical 100 Hrs

Dispensing of at least 100 products covering a wide range of preparations such as mixtures,
emulsions, lotions, liniments, ENT preparations, ointments, suppositories, powders, incompatible
prescriptions etc.

REFERENCE BOOKS (LATEST EDITION)

Pharmaceutics II (D.Ph. 201T & D.Ph. 202P)

1. Indian Pharmacopoeia.
2. British Pharmacopoeia.
3. National Formularies (N.F.I., B.N.P.)
4. Martindale‟s Extra pharmacopoeia.
5. Carter S. J., Cooper Gunn‟s Dispensing for Pharmaceutical Students, CBS Publishers, Delhi.
6. Remington‟s The Science and Practice of Pharmacy, Mack Publishing Co. Easton,
Pennsylvania.
7. The British Pharmaceutical Codex, The Pharmaceutical Press, London, Convention, Mack Pub
Co., Easton PA.
8. Hoover J.E., Dispensing of Medication, Mack Publishing Co., Easton, Pennsylvania.
9. Martin E. W., Dispensing of Medication, Mack Publishing Co., Easton PA.
D.Ph. 203T Pharmaceutical Chemistry-II, Theory 100 Hrs

Unit-I

1. Introduction to the nomenclature of organic chemical systems with particular reference to

heterocyclic system containing upto 3 rings.
2. The chemistry of following pharmaceutical organic compounds covering their nomenclature,
chemical structure, uses and the important physical and chemical properties (chemical
structure of only those compounds marked with asterisk(*).

The stability and storage conditions and the different types of pharmaceutical formulations of
these drugs and their popular brand names.

Antiseptics and disinfectants—proflavine*, benzalkoniumchloride, cetrimide, chlorocresol*,

chloroxylene, formaldehyde solution, hexachlorophene, liquified phenol, nitrofurantoin.

Sulfonamides—sulfadiazine, sulfaguanidine*, phthalylsulfathiazole, succinylsulfathiazole,

sulfadimethoxine, sulfamethoxypyridazine, sulfamethoxazole, co-trimoxazole, sulfacetamide*.

Antileprotic drugs—clofazimine, thiambutosine, dapsone*, solapsone.

Anti-tubercular drugs—isoniazid*, PAS*, streptomycin, rifampicin, ethambutol*, thiacetazone,

ethionamide, cycloserine, pyrazinamide*.

Antiamoebic and anthelminitic drugs—emetine, metronidazole*, halogenated hydroxyquinolines,

diloxanide furoate, paromomycin, piperazine*, mebendazole, D.E.C.*.

Antimalarial drugs—chloroquine*, amodiaquine, primaquine, proguanil, pyrimethamine*, quinine,

trimethoprim.

Unit-II

Antibiotics—benzyl penicillin*, phenoxy methyl penicillin*, benzathine penicillin, ampicillin*,

cloxacillin, carbenicillin, gentamicin, neomycin, erythromycin, tetracycline, cephalexin,
cephaloridine, cephalothin, griseofulvin, chloramphenicol.

Antifungal agents—undecyclenic acid, tolnaftate, nystatin, amphotericin B, hamycin.

Tranquilizers—chlorpromazine*, prochlorperazine, trifluoperazine, thiothixene, haloperidol*,

triperiodol, oxypertine, chlordizepoxide, diazepam* lorazepam, meprobamate.

Hypnotics—phenobarbitone*, butobarbitone, cyclobarbitone, nitrazepam, glutethimide*,

methyprylone, paraldehyde, triclofos sodium.

Unit-III

General anaesthetics—halothane*, cyclopropane*, diethyl ether*, methohexital sodium,

thiopental sodium, trichloroethylene.

Antidepressant drugs—amitriptyline, nortryptyline, imipramine*, phenelzine, tranylcypromine.

Analeptics—theophylline, caffeine*, coramine*, dextro-amphetamine.

Adrenergic drugs—adrenaline*, noradrenaline, isoprenaline*, phenylephrine, salbutamol,

terbutaline, ephedrine*, pseudoephedrine.

Adrenergic antagonist—tolazoline, propranolol*, practolol.

Cholinergic drugs—neostigmine*, pyridostigmine, pralidoxime, pilocarpine, physostigmine*.

Cholinergic antagonists—atropine*, hyoscine, homatropine, propantheline*, benztropine,

tropicamide, biperiden*.

Unit-IV

Diuretic drugs—furosemide*, chlorothiazide, hydrochlorothiazide* benzthiazide, urea*, mannitol*,

ethacrynic acid.

Cardiovascular drugs—ethyl nitrite*, glyceryl trinitrate, alpha methyl dopa, guanethidine, clofibrate,
quinidine.

Hypoglycemic agents—insulin, chlorpropamide*, tolbutamide, glibenclamide, phenformin*,

metformin.

Coagulants and anticoagulants—heparin, thrombin, menadione*, bishydroxycoumarin, warfarin

sodium.

Local anaesthetics—lignocaine*, procaine*, benzocaine,

Histamine and antihistaminic agents—histamine, diphenhydramine*, promethazine,

cyproheptadine, mepyramine, pheniramine, chlorpheniramine*.

Unit-V
Analgesics and antipyretics—morphine, pethidine*, codeine, methadone, aspirin*, paracetamol*,
analgin, dextropropoxyphene, pentazocine.

Nonsteroidal antiinflammatory agents—indomethacin*, phenylbutazone*, oxyphenbutazone,

ibuprofen.

Thyroxine and antithyroids—thyroxine*, methimazloe, methylthiouracil, propylthiouracil.

Diagnostic agents—iopanoic acid, propyliodone, sulfobrompthalein, sodium indigotindisulfonate,

indigocarmine, evans blue, congo red, fluorescein sodium.

*Anticonvulsants, cardiac glycosides, antiarrhythmics, antihypertensives and vitamins.

Steroidal drugs—betamethasone, cortisone, hydrocortisone, prednisolone, progesterone,

testosterone, oestradiol, nandrolone.

Antineoplastic drugs—actinomycin, azathioprine, busulphan, chloramubucil, cisplatin,

cyclophosphamide, daunorubicin hydrochloride, fluorouracil, mercaptopurine,
methotrexate, mytomycin.
 D.Ph. 204P Pharmaceutical Chemistry-II, Practical 75 Hrs

1. Systematic qualitative testing of organic drugs involving solubility determination, melting point
and/or boiling point, detection of elements and functional groups (10 compounds).
2. Official identification tests for certain groups of drugs included in the I.P., like barbiturates,
sulfonamides, phenothiazines, antibiotics etc. (8 compounds).
3. Preparation of three simple organic preparations.

REFERENCE BOOKS (LATEST EDITION)

Pharmaceutical Chemistry II (D.Ph. 203T & D.Ph. 204P)

1. Pharmacopoeia of India.
2. British Pharmaceutical codex,
3. Martindale‟s Extra pharmacopoeia.
D.Ph. 205T Pharmacology and Toxicology, Theory 75 Hrs

Unit-I

1. Introduction to pharmacology, scope of pharmacology.

2. Routes of administration of drugs, their advantages and disadvantages.
3. Various processes of absorption of drugs and the factors affecting them. Metabolism,
distribution and excretion of drugs.
4. General mechanism of drugs action and the factors which modify drugs action.

Unit-II

5. Pharmacological classification of drugs. The discussion of drugs should emphasise the

following aspects:
(i) Drugs acting on the central nervous system:
(a) General anaesthetics, adjunction to anaesthesia, intravenous anesthetics.
(b) Analgesic, antipyritic and non-steroridal antiinflammatory drugs, narcotic analgesics,
antirheumatic and antigout remedies, sedatives and hypnotics,
psychopharmacological agents, anti-convulsants, analeptics.

(c) Centrally acting muscle relaxants and antiparkinsonism agents.

Unit-III

(ii) Local anaesthetics.

(iii) Drugs acting on autonomic nervous system.
(a) Cholinergic drugs, anticholinergic drugs, anticholinesterase drugs.
(b) Adrenergic drugs and adrenergic receptor blockers.
(c) Neurone blockers and ganglion blockers.
(d) Neuromuscular blockers, drugs used in myasthenia gravis.
(iv) Drugs acting one eye, mydriactics, drugs used in glaucoma.

Unit-IV

(v) Drugs acting on respiratory system-respiratory stimulants, bronchodilators, nasal

decongestants, expectorants and antitussive agents.
(vi) Antacids, physiological role of histamine and serotonin, histamine and antihistamines,
prostaglandins.
(vii) Cardiovascular drugs, cardiotonics, antiarrhythmic agents, antianginal agents,
antihypertensive agents, peripheral vasodilators and drugs used in atherosclerosis.
(viii) Drugs acting on the blood and blood forming organs. Haematinics, coagulants and
anticoagulants, haemostatics, blood substitutes and plasma expanders.
(ix) Drugs affecting renal function—diuretics and antidiuretics.
(x) Hormones and hormone antagonists—hypoglycemic agents, antithyroid drugs, sex
hormones and oral contraceptives, corticosteroids.
(xi) Drugs acting on digestive system—carminatives, digestants, bitters, antacids and drugs
used in peptic ulcer, purgatives, and laxatives, antidiarrohoeals, emetics, antiemetics,
antispasmodics.
Unit-V

6. Chemotherapy of microbial disease: urinary antiseptics, sulfonamides, penicillins,

streptomycin, tetracyclines and other antibiotics, antitubercular agents, antifungal agents,
antiviral drugs, antileprotic drugs.
7. Chemotherapy of protozoal diseases, anthelminitc drugs.
8. Chemotherapy of cancer.
9. Disinfectants and antiseptics.
A detailed study of the action of drugs on each organ is not necessary.
 D.Ph. 206P Pharmacology and Toxicology, Practical 50 Hrs

The first six of the following experiments will be done by the students while the remaining will be
demonstrated by the teacher.
1. Effect of potassium and calcium, acetylcholine and adrenaline on frog‟s heart.
2. Effect of acetylcholine on rectus abdominis muscle of frog and guinea pig ileum.
3. Effect of spasmogens and relaxants on rabbits intestine.
4. Effect of local anaesthetics on rabbit cornea.
5. Effect of mydriatics and miotics on rabbit eye.
6. To study the action of strychnine on frog.
7. Effect of digitalis on frogs heart.
8. Effect of hypnotics in mice.
9. Effect of convulsants and anticonvulsants in mice or rats.
10. Test for pyrogens.
11. Taming and hypnosis potentiating effect of chlorpormazine in mice/rats.
12. Effect of diphenhydramine in experimentally produced asthma in guinea pigs.

REFERENCE BOOKS (LATEST EDITION)

Pharmacology & Toxicology (D.Ph. 205T & D.Ph. 206P)
1. Goyal R.K., Derasari & Gandhi‟s Elements of Pharmacology, B. S. Shah Prakashan.
2. Satoskar & Bhandarkar, Pharmacology & Pharmacotherapeutics I & II, Popular Prakashan,
Bombay.
3. Applied Therapeutics: The clinical use of Drugs, applied Therapeutics, Inc.
4. Crossland J. and Thomsen J.H.; Essential of Pharmacology; Harper & Raw Publishers NY.
5. Barar F. S. K., Essentials of Therapeutics; Interprint New Delhi.
6. Craig C. R. & Stizel R. R., Modern Pharmacology, Little Brown and Company.
7. Davidson‟s Principles and Practice of Medicine, ELBS/Churchill Livingstone.
8. J.G.Hardman, L.E., Limbird, P.B.Molinoss, R.W.Rudden & A. G. Gil, Goodman & Gilmans, The
Pharmacological basis of Therapeutics, Pergamon Press.
9. Herindal E. T. & Hirschman J.L., Willams and Wilkins, Clinical Pharmacy and Therapeutics.
10. Katzung B. G., Basic and Clinical Pharmacology, Prentice Hall International.
11. Lawrence D.R. and Bennet P. N., Clinical Pharmacology; Churchill Livingstone.
12. Myeek M. J., Gertner S. B. & Perper M. M., Pharmacology Lippincatt‟s Illustrated Reviews,
Lippinocott Company, Philadelphia.
13. Panl L., Chapmom and Hall, Principles of Pharmacology.
14. Dipiro, J.L.Elseuier, A Pathophysiological Approach: Phermacotherpay.
15. Rang M.P., Dale M.M., Riter J.M.,Pharmacology, Churchill Liningstone.
16. Robbinson S. L. and Kumar V.; Basic Pathology, W. B. Saunders Co.
17. Theoharides T. C., Pharmacology; Little Brown & Co.
18. Turner; Screening of drugs.
19. B. C. Bose, Pharmacology
20. James crossland, Levi‟s Pharmacology
21. Ghosh, Pharmacology materia medical and therapeutics.
22. Goyal R. K., Bhat R. and Burande M. K., Text Book of Clincal Pharmacy, Shah Publication.
23. Goyal R. K., Text Book of Experimental Pharmacology, Shah Publication.
24. Ghosh M.N., Fundamentals of Experimental Pharmacology, Scientific Book Agency, Calcutta.
25. Kulkarni S. K., Hand Book of Experimental Pharmacology, Vallabh Prakashan, Delhi.
26. Sharma V.N., Essentials of Pharmacology, CBS Publishers, New Delh
 D.Ph. 207T Pharmaceutical Jurisprudence, Theory 50 Hrs

Unit-I

1. Origin and nature of pharmaceutical legislation in India, its scope and objectives. Evolution
of the “Concept of Pharmacy” as an integral part of the health care system.
2. Brief introduction to the study of the following acts:
(i) Poisons Act 1919 (as amended to date)
(ii) Medicinal and toilet preparations (excise duties) Act, 1955 (as amended to date).
(iii) Medical termination of pregnancy act, 1971 (as amended to date).

Unit-II

3. Principles and significance of professional ethics. Critical study of the code of

pharmaceutical ethics drafted by Pharmacy Council of India.
4. Pharmacy Act, 1948—the general study of the Pharmacy Act with special reference to
education regulations, working of state and central councils, constitution of these councils
and functions, registration procedures under the Act.

Unit-III

5. The Drugs and Magic Remedies (Objectionable Advertisement) Act, 1954—general study of
the act, objectives, special reference to be laid on advertisements, magic remedies and
objectionable and permitted advertisements, diseases which cannot be claimed to be cured.
6. Narcotic Drugs and Psychotropic Substances Act, 1985-a brief study of the act with special
reference to its objectives, offences and punishment.

Unit-IV

7. The Drugs and Cosmetics Act, 1940—general study of the Drugs and Cosmetics Act and
the rules there under. Definitions and salient features related to retail and wholesale
distribution of drugs. Procedure and formalities in obtaining licences under the rule.

Unit-V

8. The powers of inspectors, the sampling procedures.

9. Facilities to be provided for running a pharmacy effectively. General study of the schedules
with special reference to schedules C, C1, F, G, J, H, P and X and salient features of
labeling and storage conditions of drugs.

10. Latest drugs (price control) order in force.

REFERENCE BOOKS (LATEST EDITION)

Pharmaceutical Jurisprudence (D.Ph. 207T)

1. Bare Acts of the said laws published by Government.

 D.Ph. 208T Drug Store and Business Management, Theory 50 Hrs

PART-I COMMERCE (50 hours)

Unit-I

1. Introduction—trade, industry and commerce, functions and subdivision of commerce,

introduction to elements of economics and management.
2. Channels of distribution.
3. Drug house management—selection of site, space lay out and legal requirements.
Importance and objectives of purchasing, selection of suppliers, credit information, tenders,
contracts and price determination and legal requirements thereto.
Codification, handling of drug stores and other hospital supplies.

Unit-II

4. Forms of business organizations.

5. Recruitment, training, evaluation and compensation of the pharmacist.
6. Banking and finance-service and functions of bank, finance planning and sources of finance.

Unit-III

7. Inventory control—objects and importance, modern techniques like ABC, VED analysis, the
lead time, inventory carrying cost, safety stock, minimum and maximum stock levels, economic
order quantity, scrap and surplus disposal.
8. Sales promotion, market research, salesmanship, qualities of a salesman, advertising and
window display.

PART-II ACCOUNTANCY (25 hours)

Unit-IV

9. Introduction to the accounting concepts and conventions. Double entry book keeping, different
kinds of accounts.
10. Cash book.

Unit-V

11. General ledger and trial balance.

12. Profit and loss account and balance sheet.
13. Simple techniques of analyzing financial statements. Introduction to budgeting.

REFERENCE BOOKS (LATEST EDITION)

Drug Store and Business Management (D.Ph. 208T)

1. Remington‟s Pharmaceutical Sciences.
D.Ph. 209T Hospital and Clinical Pharmacy , Theory 75 Hrs
PART-I HOSPITAL PHARMACY:

Unit-I

1. Hospital—definition, function, classification based on various criteria, organization,

management and health delivery system in India.
2. Hospital pharmacy:
(a) Definition
(b) Functions and objectives of hospital pharmaceutical services.
(c) Location, layout, flow chart of materials and men.
(d) Personnel and facilities requirements including equipments based on individual and basic
needs.
(e) Requirements and abilities required for hospital pharmacists.
3. Drug distribution system in hospitals.
(a) Out-patient services
(b) In-patient services—(a) types of services (b) detailed discussion of unit dose system,
floor ward stock
system, satellite pharmacy services, central sterile services, bed side pharmacy.

Unit-II

4. Manufacturing:
(a) Economical considerations, estimation of demand.
(b) Sterile manufacture—large and small volume parenterals, facilities, requirements,
layout, production planning, man-power requirements.
(c) Non-sterile manufacture—liquid orals, externals, bulk concentrates.
(d) Procurement of stores and testing of raw materials.
5. Nomenclature and uses of surgical instruments and hospital equipments and health
accessories.
6. P.T.C. (Pharmacy Therapeutic Committee), hospital formulary system and their
organization, functioning, composition.
7. Drug information service and drug information bulletin.
8. Surgical dressing like cotton, gauze, bandages and adhesive tapes including their
pharmacopoeial tests for quality. Other hospital supply eg. I.V. sets, B.G. sets, Ryals tubes,
catheters, syringes etc.

PART II CLINICAL PHARMACY:

Unit-III

9. Introduction to clinical pharmacy practice—definition, scope.

10. Modern dispensing aspects—pharmacists and patient counseling and advice for the use of
common drugs, medication history.
11. Common daily terminology used in the practice of medicine.
12. Disease, manifestation and pathophysiology including salient symptoms to understand the
disease like tuberculosis, hepatitis, rheumatoid arthritis, cardiovascular diseases, epilepsy,
diabetes, Peptic ulcer, hypertension.
13. Bioavailability of drugs, including factors affecting it.
 Unit-IV

14. Physiological parameters with their significance.

15. Drug interactions:
(a) Definition and introduction.
(b) Mechanism of drug interaction.
(c) Drug—drug interaction with reference to analgesics, diuretics, cardiovascular drugs,
gastro intestinal agents, vitamins and hypoglycemic agents.
(d) Drug-food interaction.
16. Adverse drug reactions.
(a) Definition and significance.
(b) Drug-induced diseases and teratogenicity.

Unit-V

17. Drugs in clinical toxicity—introduction, general treatment of poisoning, systemic antidotes,

treatment of insecticide poisoning, heavy metal poison, narcotic drugs, barbiturate,
organophosphorus poisons.
18. Drug dependences, drug abuse, addictive drugs and their treatment, complications.
19. Application of computers in maintenance of records, inventory control, medication
monitoring, drug information and data storage and retrieval in hospital retail pharmacy
establishment.

D.Ph. 210P Hospital and Clinical Pharmacy, Practical 75 Hrs

1. Preparation of transfusion fluids.

2. Testing of raw materials used in (1)

3. Evaluation of surgical dressings.
4. Sterilization of surgical instruments, glassware and other hospital supplies.
5. Handling and use of data processing equipments.

REFERENCE BOOKS (LATEST EDITION)

Hospital and Clinical Pharmacy (D.Ph. 209T & D.Ph. 210P)

1. Remington‟s Pharmaceutical Sciences
2. Martindale‟s Extra pharmacopoeia.