CONNECTIVE TISSUE CELLS
Mesodermal embryonic all /gives rise to connective tissue
>
-
Mesenchymal
· immaturealls >
-
They surate extracellular matrix
.
cell >
-
Fibroblast (Mature (
(Cartilage)
N
Collagen
Chondroblast
>
- >
-
Chondrocyte
fibres osteoblast
>
-
> Oshocyte (Bonc)
Elastic
fibres
Mastlbs - ① Fibroblast : -
large Hat,
all with
branching processes
.
Blood
vessel · Most numerous
· secrates fibry
Macrophage
Collagen
Ground
substance
② Adipocyte
(fat cell)
>
- Store fats
Skin
found dap in
·
Extracellular
matrix
Provides an
insulating
·
layer
Produce histamine (hads to vasodilation blood vessels)
of reaction
.
3 Mast Cell : >
- small
and responsible for immflamatory
is .
.
4 White A ll
Blood >
-
Helps in immune response
nature
.
5
Macrophage >
- Develops from monocytes ; phagocytotic in
Fixed Alvcolar macrophage
Macrophage
:
Cg
· - -
>
-
splenic macrophage
to the site
·
Wandering Macrophage
- Move
of
infection .
6. PlasmaCells >
- Small alls that
develop from Blymphocytes .
·
Produus antibodies .
Connective Tissue Extra Cellular Matrix
(w
① Ground Substance : -
Component of connective tissue als
and fibres Substance be -Fluid ; Samifluid ; Y latinous or
calcifical
may
.
combination and proteins.
It contains - ① water and complex of polysaccharides
&
Glucosaminoglycans (CAG's)
3
·
Hyaluronic Acid >
-
↓
· chondrotin sulphate
·
Dermaten Sulphate They Nap water and
·
Karatan Sulphate make ground substance
Jelly like
.
Acid-Binds all
together ;
lubrication in joints
·
Hyaluronoic
and maintains the shape of eye ball
.
Hyaluronidase Greakdown H A
enzyme
- .
.
-
blood vessels
.
Sulphate
Chondrotin : -
Support and adhesivenes to done cartilage and
,
Dermatan
Sulphate Support tendons blood vesds and Heart values
·
:
-> ,
Karatan Sulphate : -Borc ; Cartilage
and cornea
of eye
- prokin
GAG gets associated with -
Proteoglycans
Stein
·
Adhesion Prokins arepresent
also in
ground substance
>
- Main protein (Fidroncctin)
D
binds collagin fibre
② Fibers
9) Collagen Fibres : -
Strong ; flexible ; made
up of
connective issue
collagen protein . Found in most type of
eg
: -Bone ;
cartilage ; tendons ; ligaments
diameter ; forms network ; made
6) Elastic fibres : - Smaller in a
up
surrounded
of protein
clastin and is
by a
glycoprotein
called fibrillin
.
tissue
Found in Skin ; blood vese wall and
lang Forms basement
) Reticular Fibre : - Made
up of collagen arranged membrancalso
Finc bundles with a
coating of glycoprotein ↑
-
in
Much this new than collagen fibres ; provides
and .
strength forms stroma
support reticular connective tissue
which
>
- They have
live hyhph nodes
spleen and
supports soft organ
Classification Connective Tissue
of
-- Mature connective tissue
Embryonic Connective tissue
S
·
Mesenchyma
·
Mucous connective tissue
-
↓
Bone
loose Connective Tissue Dansc Connective Tissue cartilage
·
Dense regular
·
Hyaline
·
Arcolar Connective Tissue ·
Fibro V
Tissue
· Dense irregular
·
Adipose Elastic
·
Elastic Fluid
Connective
Reticular Connective Tissue
·
·
Tissue
·
Blood
·
Lymph
·
Connective tissue is one
of the most abundant and
widely distributed tissue in our
.
body
It binds
supports and strengthens other
body tissue
·
, .
Extra cellular Matrix
>
- (is scorted
by connective hissue alls)
Connective Tissue
als
vascular
· Connective Issue is
highly .
exception-
Cartilage
(avascular
blood
tindons
(scanty supply
· Connective tissue are
supplied with nerves
.
exceptio- Cartilage
>
-
Wharton's
jelly
- -
>
-
derived from fibroblast
tissue
· White Adipose
· Brown Adipose Lissue - Dark in color ; pigmented
blood
mitochondria & more
supply .
Conly in
very
small amt in
adults
=>
Somewhat pliable
flat tendons
*
A
-
