23/10/2024, 20:43 Antibiotic chart

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ANTIBIOTIC CHART
TOP
ACRONYMS Acronyms
CEPHALOSPORINS AAP - American Academy of
Pediatrics recommendation
Cefadroxil (Duricef®) 1st
ACG - American College of
Cephalexin (Keflex®) 1st
Gastroenterology recommendation
Cefaclor (Ceclor®) 2nd
ADA - American Dental Association
Cefprozil (Cefzil®) 2nd
AHA - American Heart Association
Cefuroxime (Ceftin®) 2nd
recommendation
Cefdinir (Omnicef®) 3rd
CDC - Centers for Disease Control
Cefditoren (Spectracef®) 3rd
recommendation
Cefixime (Suprax®) 3rd
CTE - dosing based on clinical
Cefpodoxime (Vantin®) 3rd trial(s) and/or expert opinion
Ceftibuten (Cedax®) 3rd IDSA - Infectious Disease Society of
Ceftriaxone (Rocephin®) 3rd America recommendation
Ceph generations (IV&PO) IM - Intramuscular
CLINDAMYCIN (CLEOCIN®) MRSA - Methicillin-resistant
FOSFOMYCIN (MONUROL®) Staphylococcus aureus
LEFAMULIN (XENLETA®) PI - Manufacturer's prescribing
information
OXAZOLIDINONES
TMP - Trimethoprim
MACROLIDES
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®) Cefadroxil
NITROIMIDAZOLES Duricef®

PENICILLINS
Dosage forms
QUINOLONES
Capsule
RIFAMYCINS
500 mg ($)
SULFONAMIDES
TETRACYCLINES Tablet
OPHTHALMIC ANTIBIOTIC TABLE 1000 mg ($)

OTIC ANTIBIOTIC TABLE

Suspension
250 mg/5 ml ($-$$)
500 mg/5 ml ($-$$)

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23/10/2024, 20:43 Antibiotic chart

Dosing
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Pediatric
ANTIBIOTIC CHART Impetigo - 30 mg/kg/day (max
1000 mg/day) given once daily
TOP
or divided into 2 doses (PI)
ACRONYMS Skin infections - 30 mg/kg/day
CEPHALOSPORINS (max 1000 mg/day) given in 2
Cefadroxil (Duricef®) 1st divided doses (PI)
Cephalexin (Keflex®) 1st Strep throat - 30 mg/kg once
Cefaclor (Ceclor®) 2nd daily (max 1000 mg/day) for 10
Cefprozil (Cefzil®) 2nd days (IDSA)
Cefuroxime (Ceftin®) 2nd Urinary tract infection - 30
Cefdinir (Omnicef®) 3rd mg/kg/day (max 1000 mg/day)
Cefditoren (Spectracef®) 3rd given in 2 divided doses (PI)
Cefixime (Suprax®) 3rd
Adults
Cefpodoxime (Vantin®) 3rd
Skin infections - 1000 mg/day
Ceftibuten (Cedax®) 3rd
given once daily or divided into
Ceftriaxone (Rocephin®) 3rd
2 doses (PI)
Ceph generations (IV&PO)
Strep throat - 1000 mg/day
CLINDAMYCIN (CLEOCIN®)
given once daily or divided into
FOSFOMYCIN (MONUROL®) 2 doses for 10 days (IDSA)
LEFAMULIN (XENLETA®) Urinary tract infection 1000 -
OXAZOLIDINONES 2000 mg/day given once daily
or divided into 2 doses for 3 - 7
MACROLIDES
days (IDSA, PI)
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®) Other
NITROIMIDAZOLES
Cefadroxil is a first generation
PENICILLINS
cephalosporin
QUINOLONES May take without regard to food
RIFAMYCINS Kidney disease (adults)
CrCl < 50 ml/min: dose
SULFONAMIDES
adjustment recommended;
TETRACYCLINES see cefadroxil PI
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE

Cephalexin
Keflex®

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23/10/2024, 20:43 Antibiotic chart

Dosage forms
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Capsule
ANTIBIOTIC CHART 250 mg ($)
500 mg ($)
TOP
750 mg ($$$-$$$$)
ACRONYMS
CEPHALOSPORINS Tablet
Cefadroxil (Duricef®) 1st 250 mg ($-$$)
Cephalexin (Keflex®) 1st 500 mg ($-$$)
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd Suspension
Cefuroxime (Ceftin®) 2nd 125 mg/5 ml ($)
Cefdinir (Omnicef®) 3rd 250 mg/5 ml ($)
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd Dosing
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd Pediatric
Cellulitis (non-MRSA) - 25 - 50
Ceftriaxone (Rocephin®) 3rd
mg/kg/day (max 2000 mg/day)
Ceph generations (IV&PO)
given in 4 divided doses for 5 -
CLINDAMYCIN (CLEOCIN®)
10 days (IDSA)
FOSFOMYCIN (MONUROL®) Endocarditis prophylaxis - 50
LEFAMULIN (XENLETA®) mg/kg (max 2000 mg) 30 - 60
OXAZOLIDINONES minutes before procedure
(penicillin allergic without
MACROLIDES
severe reaction) (AHA)
NITAZOXANIDE (ALINIA®)
Impetigo - 25 - 50 mg/kg/day
NITROFURANTOIN (MACROBID®) (max 1000 mg/day) given in 3 –
NITROIMIDAZOLES 4 divided doses for 7 days
PENICILLINS (IDSA)
Otitis media - 75 - 100
QUINOLONES
mg/kg/day given in 4 divided
RIFAMYCINS doses for 5 - 10 days (PI)
SULFONAMIDES Strep throat - 40 mg/kg/day
(max 1000 mg/day) given in 2
TETRACYCLINES
divided doses for 10 days
OPHTHALMIC ANTIBIOTIC TABLE (IDSA)
OTIC ANTIBIOTIC TABLE Urinary tract infection - 50 - 100
mg/kg/day (max 2000 mg/day)
given in 4 divided doses for 7 -
14 days (CTE)

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JOIN Adults (15 years and older)

Straight Healthcare NEWSLETTER CellulitisSUBSCRIBE LOGIN
(non-MRSA) - 500 mg
4 times a day for 5 - 10 days
ANTIBIOTIC CHART
(IDSA)
TOP Diabetic foot ulcer (mild, non-
ACRONYMS MRSA) - 500 mg 4 times a day
CEPHALOSPORINS for 7 - 14 days (IDSA)
Endocarditis prophylaxis - 2
Cefadroxil (Duricef®) 1st
grams 30 - 60 minutes before
Cephalexin (Keflex®) 1st
procedure (penicillin allergic
Cefaclor (Ceclor®) 2nd
without severe reaction) (AHA)
Cefprozil (Cefzil®) 2nd
Impetigo - 250 mg 4 times a
Cefuroxime (Ceftin®) 2nd
day for 7 days (IDSA)
Cefdinir (Omnicef®) 3rd
Pulpitis (toothache) - 500 mg
Cefditoren (Spectracef®) 3rd four times a day for 3 - 7 days
Cefixime (Suprax®) 3rd (ADA)
Cefpodoxime (Vantin®) 3rd Strep throat - 500 mg twice a
Ceftibuten (Cedax®) 3rd day for 10 days (IDSA)
Ceftriaxone (Rocephin®) 3rd Urinary tract infection - 500 mg
Ceph generations (IV&PO) twice a day for 7 days (IDSA,
CLINDAMYCIN (CLEOCIN®) PI)
FOSFOMYCIN (MONUROL®) Urinary tract infection,
prophylaxis
LEFAMULIN (XENLETA®)
Postcoital - 250 mg one time
OXAZOLIDINONES
postcoital (CTE)
MACROLIDES Continuous - 125 - 250 mg
NITAZOXANIDE (ALINIA®) once daily (CTE)
NITROFURANTOIN (MACROBID®)
Other
NITROIMIDAZOLES
PENICILLINS Cephalexin is a first generation
QUINOLONES cephalosporin
May take without regard to food
RIFAMYCINS
Cephalexin may increase
SULFONAMIDES metformin levels
TETRACYCLINES Kidney disease
CrCl ≥ 60 ml/min: no dose
OPHTHALMIC ANTIBIOTIC TABLE
adjustment necessary
OTIC ANTIBIOTIC TABLE
CrCl 30 - 59 ml/min: no dose
adjustment; maximum daily
dose should not exceed
1000 mg

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23/10/2024, 20:43 Antibiotic chart

CrCl 15 - 29 ml/min: 250 mg

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8 hours or every 12
hours
ANTIBIOTIC CHARTCrCl 5 - 14 ml/min
TOP (nondialysis): 250 mg every
24 hours
ACRONYMS
CrCl 1 - 4 ml/min
CEPHALOSPORINS
(nondialysis): 250 mg every
Cefadroxil (Duricef®) 1st 48 hours or every 60 hours
Cephalexin (Keflex®) 1st
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd
Cefaclor
Cefditoren (Spectracef®) 3rd Ceclor®
Cefixime (Suprax®) 3rd
Cefpodoxime (Vantin®) 3rd Dosage forms

Ceftibuten (Cedax®) 3rd Capsule

Ceftriaxone (Rocephin®) 3rd 250 mg ($)
Ceph generations (IV&PO) 500 mg ($)
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®) Suspension
LEFAMULIN (XENLETA®) 125 mg/5 ml ($)
250 mg/5 ml ($$$)
OXAZOLIDINONES
375 mg/5 ml ($$-$$$)
MACROLIDES
NITAZOXANIDE (ALINIA®) Dosing
NITROFURANTOIN (MACROBID®)
NITROIMIDAZOLES Pediatric
Cellulitis (non-MRSA) - 20 - 40
PENICILLINS
mg/kg/day (max 1000 mg/day)
QUINOLONES given in 3 divided doses (PI)
RIFAMYCINS Otitis media - 40 mg/kg/day
(max 1000 mg/day) given in 2
SULFONAMIDES
divided doses (PI)
TETRACYCLINES Pneumonia, community-
OPHTHALMIC ANTIBIOTIC TABLE acquired - 20 - 40 mg/kg/day
OTIC ANTIBIOTIC TABLE (max 1000 mg/day) given in 3
divided doses (PI)
Strep throat - 20 - 40
mg/kg/day (max 1000 mg/day)
given in 2 divided doses for 10
days (PI)
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Urinary tract infection - 20 - 40

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mg/kg/day (max 1000LOGIN
mg/day)
given in 3 divided doses (PI)
ANTIBIOTIC CHART
TOP Adults
Cellulitis (non-MRSA) - 250 -
ACRONYMS
500 mg every 8 hours (PI)
CEPHALOSPORINS
Otitis media - 250 - 500 mg
Cefadroxil (Duricef®) 1st every 8 hours (PI)
Cephalexin (Keflex®) 1st Pneumonia, community-
Cefaclor (Ceclor®) 2nd acquired - 500 mg every 8
Cefprozil (Cefzil®) 2nd hours (PI)
Cefuroxime (Ceftin®) 2nd Strep throat - 250 - 500 mg
Cefdinir (Omnicef®) 3rd every 8 hours for 10 days (PI)
Cefditoren (Spectracef®) 3rd Urinary tract infection - 250 -
Cefixime (Suprax®) 3rd 500 mg every 8 hours (PI)
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd Other
Ceftriaxone (Rocephin®) 3rd
Cefaclor is a second generation
Ceph generations (IV&PO)
cephalosporin
CLINDAMYCIN (CLEOCIN®)
Food slows absorption but
FOSFOMYCIN (MONUROL®) does not affect the extent of
LEFAMULIN (XENLETA®) absorption
OXAZOLIDINONES Liver disease - manufacturer
makes no dosage
MACROLIDES
recommendation
NITAZOXANIDE (ALINIA®)
Kidney disease - no dose
NITROFURANTOIN (MACROBID®) adjustment necessary
NITROIMIDAZOLES
PENICILLINS
QUINOLONES
RIFAMYCINS Cefprozil
Cefzil®
SULFONAMIDES
TETRACYCLINES Dosage forms
OPHTHALMIC ANTIBIOTIC TABLE
Tablet
OTIC ANTIBIOTIC TABLE
250 mg ($)
500 mg ($)

Suspension
125 mg/5 ml ($)
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250 mg/5 ml ($)

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Dosing
ANTIBIOTIC CHART
TOP Pediatric (6 months - 12 years)
Cellulitis - 20 mg/kg/day (max
ACRONYMS
1000 mg/day) given once daily
CEPHALOSPORINS
for 10 days (PI)
Cefadroxil (Duricef®) 1st Otitis media - 30 mg/kg/day
Cephalexin (Keflex®) 1st (max 1000 mg/day) given in 2
Cefaclor (Ceclor®) 2nd divided doses for 10 days (PI)
Cefprozil (Cefzil®) 2nd Pneumonia, community-
Cefuroxime (Ceftin®) 2nd acquired - 30 mg/kg/day (max
Cefdinir (Omnicef®) 3rd 1000 mg/day) given in 2
Cefditoren (Spectracef®) 3rd divided doses for 7 - 10 days
Cefixime (Suprax®) 3rd (IDSA)
Cefpodoxime (Vantin®) 3rd Sinusitis - 15 - 30 mg/kg/day
Ceftibuten (Cedax®) 3rd (max 1000 mg/day) given in 2
Ceftriaxone (Rocephin®) 3rd divided doses for 10 days (PI)
Ceph generations (IV&PO) Strep throat - 15 mg/kg/day
(max 500 mg/day) given in 2
CLINDAMYCIN (CLEOCIN®)
divided doses for 10 days (PI)
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Adolescents and Adults (age 12
OXAZOLIDINONES years and older)
MACROLIDES Cellulitis - 250 - 500 mg twice a
day or 500 mg once daily for 10
NITAZOXANIDE (ALINIA®)
days (PI)
NITROFURANTOIN (MACROBID®)
Sinusitis - 250 - 500 mg twice a
NITROIMIDAZOLES day for 10 days (PI)
PENICILLINS Strep throat - 500 mg once
daily for 10 days (PI)
QUINOLONES
RIFAMYCINS
Other
SULFONAMIDES
Cefprozil is a second
TETRACYCLINES
generation cephalosporin
OPHTHALMIC ANTIBIOTIC TABLE May take without regard to food
OTIC ANTIBIOTIC TABLE Liver disease - no dose
adjustment necessary
Kidney disease

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CrCl ≤ 29 ml/min: - use half

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the standard dose LOGIN

ANTIBIOTIC CHART
TOP
ACRONYMS Cefuroxime
CEPHALOSPORINS Ceftin®
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st Dosage forms
Cefaclor (Ceclor®) 2nd
Tablet
Cefprozil (Cefzil®) 2nd
125 mg (?)
Cefuroxime (Ceftin®) 2nd
250 mg ($)
Cefdinir (Omnicef®) 3rd
500 mg ($)
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd
Suspension
Cefpodoxime (Vantin®) 3rd
125 mg/5 ml ($$$$)
Ceftibuten (Cedax®) 3rd 250 mg/5 ml ($$$$)
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO)
Dosing
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®) Pediatric (3 months to 12 years)
LEFAMULIN (XENLETA®) NOTE: Pediatric dosing is for
suspension only. Suspension
OXAZOLIDINONES
and tablet are not bioequivalent
MACROLIDES on a mg-to-mg basis.
NITAZOXANIDE (ALINIA®) Impetigo - 30 mg/kg/day (max
NITROFURANTOIN (MACROBID®) 1000 mg/day) given in 2
NITROIMIDAZOLES divided doses for 10 days (PI)
Otitis media - 30 mg/kg/day
PENICILLINS
(max 1000 mg/day) given in 2
QUINOLONES divided doses for 5 - 10 days
RIFAMYCINS (AAP)
SULFONAMIDES Pneumonia, community-
acquired - 30 mg/kg/day (max
TETRACYCLINES
1000 mg/day) given in 2
OPHTHALMIC ANTIBIOTIC TABLE divided doses for 7 - 10 days
OTIC ANTIBIOTIC TABLE (IDSA)
Sinusitis - 30 mg/kg/day (max
1000 mg/day) given in 2
divided doses for a minimum of
10 days (AAP)

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Strep throat - 20 mg/kg/day

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mg/day) given in 2
divided doses for 10 days (PI)
ANTIBIOTIC CHART
Urinary tract infection - 20 - 30
TOP mg/kg/day (max 1000 mg/day)
given in 2 divided doses for 7 -
ACRONYMS
14 days (CTE)
CEPHALOSPORINS
Cefadroxil (Duricef®) 1st Adolescents and Adults (13 years
Cephalexin (Keflex®) 1st and older)
Cefaclor (Ceclor®) 2nd Bite, animal - Cefuroxime 500
Cefprozil (Cefzil®) 2nd mg twice a day +
Cefuroxime (Ceftin®) 2nd Clindamycin 300 mg three
Cefdinir (Omnicef®) 3rd times a day; OR
Cefditoren (Spectracef®) 3rd Metronidazole 250 - 500 mg
Cefixime (Suprax®) 3rd three times a day (IDSA)
Cefpodoxime (Vantin®) 3rd Early Lyme disease - 500 mg
Ceftibuten (Cedax®) 3rd twice a day for 20 days (PI)
Ceftriaxone (Rocephin®) 3rd Gonorrhea - 1000 mg one time
Ceph generations (IV&PO) dose (PI)
Pneumonia, community-
CLINDAMYCIN (CLEOCIN®)
acquired - Cefuroxime 500 mg
FOSFOMYCIN (MONUROL®)
twice a day + macrolide or
LEFAMULIN (XENLETA®) doxycycline for 5 - 14 days
OXAZOLIDINONES (IDSA, PI)
MACROLIDES Sinusitis - 250 mg twice a day
for 10 days (PI)
NITAZOXANIDE (ALINIA®)
Skin infections - 250 - 500 mg
NITROFURANTOIN (MACROBID®)
twice a day for 10 days (PI)
NITROIMIDAZOLES Strep throat - 250 mg twice a
PENICILLINS day for 10 days (PI)
Urinary tract infection - 250 mg
QUINOLONES
twice a day for 7 days (IDSA,
RIFAMYCINS PI)
SULFONAMIDES
TETRACYCLINES Other

OPHTHALMIC ANTIBIOTIC TABLE Cefuroxime is a second

OTIC ANTIBIOTIC TABLE generation cephalosporin
Suspension should be taken
with food
Tablets may be taken without
regard to food

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Tablets and suspension are not

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substitutable LOGIN
on a mg-to-mg
basis
ANTIBIOTIC CHART
Kidney disease
TOP CrCl ≥ 30 ml/min - no
adjustment necessary
ACRONYMS
CrCl 10 - 29 ml/min - give
CEPHALOSPORINS
standard individual dose
Cefadroxil (Duricef®) 1st every 24 hours
Cephalexin (Keflex®) 1st CrCl < 10 ml/min - give
Cefaclor (Ceclor®) 2nd standard individual dose
Cefprozil (Cefzil®) 2nd every 48 hours
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd
Cefdinir
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd
Omnicef®
Ceftriaxone (Rocephin®) 3rd
Dosage forms
Ceph generations (IV&PO)
CLINDAMYCIN (CLEOCIN®) Capsule
FOSFOMYCIN (MONUROL®) 300 mg ($)
LEFAMULIN (XENLETA®)
Suspension
OXAZOLIDINONES
125 mg/5 ml ($)
MACROLIDES 250 mg/5 ml ($)
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®) Dosing
NITROIMIDAZOLES
Pediatric (6 months - 12 years)
PENICILLINS
Otitis media - 14 mg/kg/day
QUINOLONES (max 600 mg/day) given in 1 or
RIFAMYCINS 2 divided doses for 5 - 10 days
(AAP)
SULFONAMIDES
Sinusitis - 14 mg/kg/day (max
TETRACYCLINES 600 mg/day) given in 1 or 2
OPHTHALMIC ANTIBIOTIC TABLE divided doses for a minimum of
OTIC ANTIBIOTIC TABLE 10 days (AAP)
Skin infections - 7 mg/kg/dose
(max 300 mg/dose) twice a day
for 10 days (PI)
Strep throat - 7 mg/kg/dose
(max 300 mg/dose) twice a day
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for 5 to 10 days OR 14 mg/kg

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mg/day) once daily
for 10 days (PI)
ANTIBIOTIC CHART
TOP Adults and Adolescents (Age 13
years and older)
ACRONYMS
Pneumonia, community-
CEPHALOSPORINS
acquired - 300 mg twice a day
Cefadroxil (Duricef®) 1st for 10 days (PI)
Cephalexin (Keflex®) 1st Sinusitis - 300 mg twice a day
Cefaclor (Ceclor®) 2nd or 600 mg once daily for 10
Cefprozil (Cefzil®) 2nd days (IDSA)
Cefuroxime (Ceftin®) 2nd Skin infections - 300 mg twice a
Cefdinir (Omnicef®) 3rd day for 10 days (PI)
Cefditoren (Spectracef®) 3rd Strep throat - 300 mg twice a
Cefixime (Suprax®) 3rd day for 5 - 10 days or 600 mg
Cefpodoxime (Vantin®) 3rd once daily for 10 days (PI)
Ceftibuten (Cedax®) 3rd Urinary tract infection - 300 mg
Ceftriaxone (Rocephin®) 3rd twice a day for 3 - 7 days
Ceph generations (IV&PO) (IDSA)

CLINDAMYCIN (CLEOCIN®)
Other
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Cefdinir is a third generation
OXAZOLIDINONES cephalosporin
May take without regard to food
MACROLIDES
Iron supplements and antacids
NITAZOXANIDE (ALINIA®)
reduce cefdinir absorption. Do
NITROFURANTOIN (MACROBID®) not take within 2 hours of each
NITROIMIDAZOLES other.
PENICILLINS Cefdinir and iron may cause
stool to turn red
QUINOLONES
Liver disease - no dose
RIFAMYCINS adjustment necessary
SULFONAMIDES Kidney disease
CrCl < 30 ml/min: adult dose
TETRACYCLINES
is 300 mg once daily;
OPHTHALMIC ANTIBIOTIC TABLE pediatric dose is 7
OTIC ANTIBIOTIC TABLE mg/kg/day (max 300
mg/day) given once daily

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NEWSLETTER SUBSCRIBE LOGIN
Spectracef®
ANTIBIOTIC CHART
Dosage forms
TOP
ACRONYMS Tablet
CEPHALOSPORINS 200 mg ($$$$)
Cefadroxil (Duricef®) 1st 400 mg ($$$$)
Cephalexin (Keflex®) 1st Discontinued in U.S.
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd Dosing
Cefuroxime (Ceftin®) 2nd
Adults and Adolescents (Age 12
Cefdinir (Omnicef®) 3rd
years and older)
Cefditoren (Spectracef®) 3rd
Pneumonia, community-
Cefixime (Suprax®) 3rd
acquired - 400 mg twice a day
Cefpodoxime (Vantin®) 3rd
for 14 days (PI)
Ceftibuten (Cedax®) 3rd Skin infections - 200 mg twice a
Ceftriaxone (Rocephin®) 3rd day for 10 days (PI)
Ceph generations (IV&PO) Strep throat - 200 mg twice a
CLINDAMYCIN (CLEOCIN®) day for 10 days (PI)
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Other

OXAZOLIDINONES
Cefditoren has been
MACROLIDES discontinued in the U.S.
NITAZOXANIDE (ALINIA®) Cefditoren is a third generation
cephalosporin
NITROFURANTOIN (MACROBID®)
Take with a meal to increase
NITROIMIDAZOLES
absorption
PENICILLINS Drugs that reduce gastric
QUINOLONES acidity (e.g. antacids, H2
blockers, PPIs) decrease
RIFAMYCINS
absorption
SULFONAMIDES Liver disease
TETRACYCLINES Child-Pugh A/B: no dose
OPHTHALMIC ANTIBIOTIC TABLE adjustment necessary
Child-Pugh C: has not been
OTIC ANTIBIOTIC TABLE
studied
Kidney disease
CrCl > 50 ml/min: No dose
adjustment necessary

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23/10/2024, 20:43 Antibiotic chart

CrCl 30 - 49 ml/min: 200 mg

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a day LOGIN
CrCl < 30 ml/min: 200 mg
ANTIBIOTIC CHARTonce daily
TOP
ACRONYMS
CEPHALOSPORINS
Cefadroxil (Duricef®) 1st Cefixime
Cephalexin (Keflex®) 1st Suprax®
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd Dosage forms
Cefuroxime (Ceftin®) 2nd
Capsule
Cefdinir (Omnicef®) 3rd
400 mg ($ for 2 capsules)
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd
Tablet, chewable
Cefpodoxime (Vantin®) 3rd
100 mg ($ for 2 tablets)
Ceftibuten (Cedax®) 3rd
200 mg ($$ for 2 tablets)
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO)
Suspension
CLINDAMYCIN (CLEOCIN®) 100 mg/5 ml ($$ for 50 ml)
FOSFOMYCIN (MONUROL®) 200 mg/5 ml ($$$ for 50 ml)
LEFAMULIN (XENLETA®) 500 mg/5 ml (?)

OXAZOLIDINONES
Dosing
MACROLIDES
NITAZOXANIDE (ALINIA®) Pediatric (6 months - 12 years)
NITROFURANTOIN (MACROBID®) Sinusitis - 8 mg/kg/day (max
NITROIMIDAZOLES 400 mg/day) given in one or
two divided doses for a
PENICILLINS
minimum of 10 days. Give with
QUINOLONES clindamycin. See AAP sinusitis
RIFAMYCINS recs. (AAP, PI)
Urinary tract infection - 8
SULFONAMIDES
mg/kg/day (max 400 mg/day)
TETRACYCLINES given once daily for 7 - 14 days
OPHTHALMIC ANTIBIOTIC TABLE (CTE)
OTIC ANTIBIOTIC TABLE Urinary tract infection,
prophylaxis - 2 mg/kg/day given
once daily (CTE)

Adults and Adolescents (Age 12

years and older)
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23/10/2024, 20:43 Antibiotic chart

Gonorrhea (cervical, urethral,

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800 mg singleLOGIN
dose
(CDC)
ANTIBIOTIC CHART
TOP Other

ACRONYMS
Cefixime is a third generation
CEPHALOSPORINS cephalosporin
Cefadroxil (Duricef®) 1st May take without regard to food
Cephalexin (Keflex®) 1st Kidney disease
Cefaclor (Ceclor®) 2nd CrCl ≥ 60 ml/min: no dose
Cefprozil (Cefzil®) 2nd adjustment necessary
Cefuroxime (Ceftin®) 2nd CrCl < 60 ml/min: dose
Cefdinir (Omnicef®) 3rd adjustment recommended;
Cefditoren (Spectracef®) 3rd see Suprax PI [sec 2.3] for
Cefixime (Suprax®) 3rd recommendations
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO) Cefpodoxime
CLINDAMYCIN (CLEOCIN®) Vantin®
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Dosage forms
OXAZOLIDINONES Tablet
MACROLIDES 100 mg ($)
NITAZOXANIDE (ALINIA®) 200 mg ($)

NITROFURANTOIN (MACROBID®)
Suspension
NITROIMIDAZOLES
50 mg/5 ml ($)
PENICILLINS 100 mg/5 ml ($)
QUINOLONES
RIFAMYCINS Dosing

SULFONAMIDES
Pediatric (age 2 months through
TETRACYCLINES 12 years)
OPHTHALMIC ANTIBIOTIC TABLE Otitis media - 10 mg/kg/day
(max 400 mg/day) given in 2
OTIC ANTIBIOTIC TABLE
divided doses for 5 - 10 days
(AAP)
Pneumonia, community-
acquired - 10 mg/kg/day (max

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23/10/2024, 20:43 Antibiotic chart

400 mg/day) given in 2 divided

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doses for 7 - 10 days LOGIN
(IDSA)
Sinusitis - 10 mg/kg/day (max
ANTIBIOTIC CHART
400 mg/day) given in 2 divided
TOP doses for a minimum of 10
days (AAP)
ACRONYMS
Strep throat - 10 mg/kg/day
CEPHALOSPORINS
(max 200 mg/day) given in 2
Cefadroxil (Duricef®) 1st divided doses for 5 - 10 days
Cephalexin (Keflex®) 1st (PI)
Cefaclor (Ceclor®) 2nd Urinary tract infection - 10
Cefprozil (Cefzil®) 2nd mg/kg/day (max 400 mg/day)
Cefuroxime (Ceftin®) 2nd given in 2 divided doses for 7 -
Cefdinir (Omnicef®) 3rd 14 days (CTE)
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd Adolescents and Adults (age 12
Cefpodoxime (Vantin®) 3rd years and older)
Ceftibuten (Cedax®) 3rd Gonorrhea - 200 mg one time
Ceftriaxone (Rocephin®) 3rd dose (PI)
Ceph generations (IV&PO) Pneumonia, community-
acquired - Cefpodoxime 200
CLINDAMYCIN (CLEOCIN®)
mg twice a day + macrolide or
FOSFOMYCIN (MONUROL®)
doxycycline for 5 - 14 days
LEFAMULIN (XENLETA®) (IDSA, PI)
OXAZOLIDINONES Sinusitis - 200 mg twice a day
MACROLIDES for 10 days (PI)
Skin infections - 400 mg twice a
NITAZOXANIDE (ALINIA®)
day for 7 - 14 days (PI)
NITROFURANTOIN (MACROBID®) Strep throat - 100 mg twice a
NITROIMIDAZOLES day for 5 - 10 days (PI)
PENICILLINS Urinary tract infection - 100 mg
twice a day for 3 - 7 days
QUINOLONES
(IDSA, PI, CTE)
RIFAMYCINS
SULFONAMIDES Other
TETRACYCLINES
Cefpodoxime is a third
OPHTHALMIC ANTIBIOTIC TABLE generation cephalosporin
OTIC ANTIBIOTIC TABLE Suspension may be taken
without regard to food
Tablets should be taken with
food

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23/10/2024, 20:43 Antibiotic chart

Drugs that reduce gastric

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acidity (e.g. antacids, LOGIN
H2
blockers, PPIs) decrease
ANTIBIOTIC CHART
absorption
TOP Liver disease - no dose
adjustment necessary
ACRONYMS
Kidney disease
CEPHALOSPORINS
CrCl < 30 ml/min: increase
Cefadroxil (Duricef®) 1st dosing interval to every 24
Cephalexin (Keflex®) 1st hours
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd
Ceftibuten
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd Cedax®
Cefpodoxime (Vantin®) 3rd
Dosage forms
Ceftibuten (Cedax®) 3rd
Ceftriaxone (Rocephin®) 3rd Capsule
Ceph generations (IV&PO) 400 mg ($$$$)
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®) Suspension
LEFAMULIN (XENLETA®) 180 mg/5 ml ($$$$)

OXAZOLIDINONES
Dosing
MACROLIDES
NITAZOXANIDE (ALINIA®) Pediatric
NITROFURANTOIN (MACROBID®) Otitis media - 9 mg/kg/day
NITROIMIDAZOLES (max 400 mg/day) given once
daily for 10 days (PI)
PENICILLINS
Strep throat - 9 mg/kg/day (max
QUINOLONES 400 mg/day) given once daily
RIFAMYCINS for 10 days (PI)

SULFONAMIDES
Adolescents and Adults (age 12
TETRACYCLINES years and older)
OPHTHALMIC ANTIBIOTIC TABLE Otitis media - 400 mg once
OTIC ANTIBIOTIC TABLE daily for 10 days (PI)
Strep throat - 400 mg once
daily for 10 days (PI)

Other

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23/10/2024, 20:43 Antibiotic chart

JOIN Ceftibuten is a third generation

Straight Healthcare NEWSLETTER SUBSCRIBE LOGIN
cephalosporin
Ceftibuten should be taken at
ANTIBIOTIC CHART
least 2 hours before or one
TOP hour after a meal. Food
ACRONYMS decreases absorption.
CEPHALOSPORINS Liver disease - manufacturer
makes no dosage
Cefadroxil (Duricef®) 1st
recommendation
Cephalexin (Keflex®) 1st
Kidney disease
Cefaclor (Ceclor®) 2nd
CrCl > 50 ml/min: No dose
Cefprozil (Cefzil®) 2nd
adjustment necessary
Cefuroxime (Ceftin®) 2nd
CrCl 30 - 49 ml/min: 4.5
Cefdinir (Omnicef®) 3rd mg/kg/day or 200 mg once
Cefditoren (Spectracef®) 3rd daily
Cefixime (Suprax®) 3rd CrCl 5 - 29 ml/min: 2.25
Cefpodoxime (Vantin®) 3rd mg/kg/day or 100 mg once
Ceftibuten (Cedax®) 3rd daily
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO)
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®)
Ceftriaxone
LEFAMULIN (XENLETA®)
Rocephin®
OXAZOLIDINONES
MACROLIDES Dosage forms

NITAZOXANIDE (ALINIA®)
Vial
NITROFURANTOIN (MACROBID®) 250 mg ($)
NITROIMIDAZOLES 500 mg ($)
PENICILLINS 1000 mg ($)
2000 mg ($)
QUINOLONES
RIFAMYCINS Dosing
SULFONAMIDES
Pediatric
TETRACYCLINES
E. coli, enterotoxigenic - 50
OPHTHALMIC ANTIBIOTIC TABLE mg/kg/day IM/IV given once
OTIC ANTIBIOTIC TABLE daily for 3 days (CTE)
Endocarditis prophylaxis - 50
mg/kg (max 1000 mg) IM 30 -
60 minutes before procedure
(AHA)

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23/10/2024, 20:43 Antibiotic chart

Otitis media - 50 mg/kg/day

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(max 1000 mg) IM forLOGIN
1 to 3
days (AAP)
ANTIBIOTIC CHART
Pneumonia, community-
TOP acquired - 50 - 100 mg/kg/day
(max 2000 mg/day) IM given
ACRONYMS
once daily for 7 - 10 days
CEPHALOSPORINS
(IDSA)
Cefadroxil (Duricef®) 1st Salmonella, nontyphoidal - 100
Cephalexin (Keflex®) 1st mg/kg/day IV given in 2 divided
Cefaclor (Ceclor®) 2nd doses for 7 - 10 days (CTE)
Cefprozil (Cefzil®) 2nd Shigella - 50 mg/kg/day IM/IV
Cefuroxime (Ceftin®) 2nd given once daily for 3 days
Cefdinir (Omnicef®) 3rd (CTE/IDSA)
Cefditoren (Spectracef®) 3rd Skin infections - 50 - 75
Cefixime (Suprax®) 3rd mg/kg/day (max 2000 mg/day)
Cefpodoxime (Vantin®) 3rd given once a day or in two
Ceftibuten (Cedax®) 3rd divided doses (PI)
Ceftriaxone (Rocephin®) 3rd Vibrio vulnificus - 50 mg/kg/day
Ceph generations (IV&PO) IM/IV given once daily for 3
days (CTE)
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®)
Adults
LEFAMULIN (XENLETA®) Diabetic foot ulcer (moderate,
OXAZOLIDINONES non-MRSA) - 1 - 2 gram(s) IM
MACROLIDES once daily for 7 - 14 days
(IDSA, PI)
NITAZOXANIDE (ALINIA®)
Endocarditis prophylaxis - 1
NITROFURANTOIN (MACROBID®)
gram IM 30 - 60 minutes before
NITROIMIDAZOLES procedure (AHA)
PENICILLINS Epididymitis
Likely caused by chlamydia
QUINOLONES
or gonorrhea - Ceftriaxone
RIFAMYCINS 500 mg IM (1000 mg if ≥ 330
SULFONAMIDES lbs) single dose +
TETRACYCLINES Doxycycline 100 mg twice
daily for 10 days (CDC)
OPHTHALMIC ANTIBIOTIC TABLE
Likely caused by chlamydia,
OTIC ANTIBIOTIC TABLE gonorrhea, and/or enteric
organisms - Ceftriaxone 500
mg IM (1000 mg if ≥ 330 lbs)
single dose + Levofloxacin

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23/10/2024, 20:43 Antibiotic chart

500 mg once daily for 10

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(CDC) LOGIN
Gonorrhea (cervical, urethral,
ANTIBIOTIC CHART
rectal, pharyngeal)
TOP Patients weighing < 150 kg
(330 lbs): 500 mg IM single
ACRONYMS
dose (CDC)
CEPHALOSPORINS
Patients weighing ≥ 150 kg
Cefadroxil (Duricef®) 1st (330 lbs): 1000 mg IM single
Cephalexin (Keflex®) 1st dose (CDC)
Cefaclor (Ceclor®) 2nd Neurosyphilis (pen-allergic) - 2
Cefprozil (Cefzil®) 2nd grams IM/IV daily for 10 - 14
Cefuroxime (Ceftin®) 2nd days (CDC)
Cefdinir (Omnicef®) 3rd Pneumonia, community-
Cefditoren (Spectracef®) 3rd acquired - Ceftriaxone 1 gram
Cefixime (Suprax®) 3rd IM/IV once daily for 7 - 14 days
Cefpodoxime (Vantin®) 3rd + macrolide (CTE)
Ceftibuten (Cedax®) 3rd Salmonella, nontyphoidal - 1 - 2
Ceftriaxone (Rocephin®) 3rd gram(s) IV once daily for 5 - 10
Ceph generations (IV&PO) days (CTE/IDSA)
Syphilis (primary and
CLINDAMYCIN (CLEOCIN®)
secondary, pen-allergic) - 1
FOSFOMYCIN (MONUROL®)
gram IM/IV daily for 10 - 14
LEFAMULIN (XENLETA®) days (CDC)
OXAZOLIDINONES
MACROLIDES Other

NITAZOXANIDE (ALINIA®)
Ceftriaxone is a third
NITROFURANTOIN (MACROBID®) generation cephalosporin
NITROIMIDAZOLES Do not give to neonates ≤ 28
PENICILLINS days old with
hyperbilirubinemia
QUINOLONES
Liver disease - no dose
RIFAMYCINS adjustment necessary
SULFONAMIDES Kidney disease - no dose
adjustment necessary
TETRACYCLINES
Kidney and liver disease
OPHTHALMIC ANTIBIOTIC TABLE (concurrent) - do not exceed 2
OTIC ANTIBIOTIC TABLE grams daily

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JOINCEPHALOSPORIN GENERATIONS
Straight Healthcare NEWSLETTER
(IV&PO) SUBSCRIBE LOGIN

ANTIBIOTIC CHART
First generation Second g
TOP
ACRONYMS Cefadroxil (Duricef®) Cefaclor
CEPHALOSPORINS Cephalexin (Keflex®) Cefoxitin
Cefadroxil (Duricef®) 1st Cefazolin (Ancef®) Cefotetan
Cephalexin (Keflex®) 1st Cefprozil
Cefaclor (Ceclor®) 2nd Cefuroxim
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO) Clindamycin
CLINDAMYCIN (CLEOCIN®)
Cleocin®

FOSFOMYCIN (MONUROL®)
Dosage forms
LEFAMULIN (XENLETA®)
OXAZOLIDINONES Capsule
75 mg ($)
MACROLIDES
150 mg ($)
NITAZOXANIDE (ALINIA®) 300 mg ($)
NITROFURANTOIN (MACROBID®)
NITROIMIDAZOLES Solution
75 mg/5 ml ($$)
PENICILLINS
QUINOLONES
Vaginal cream
RIFAMYCINS 2%, 40 gm tube ($-$$)
SULFONAMIDES
Vaginal cream (Clindesse®)
TETRACYCLINES
2%, single-dose 5 gm applicator ($$$)
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE Vaginal suppository (Cleocin®)
100 mg ($$$$)
Comes in carton with 3 suppositories

Topical

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23/10/2024, 20:43 Antibiotic chart

See topical derm chart

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Dosing
ANTIBIOTIC CHART
TOP Pediatric
Cellulitis (MRSA coverage) - 30
ACRONYMS
- 40 mg/kg/day (max 1800
CEPHALOSPORINS
mg/day) given in 3 divided
Cefadroxil (Duricef®) 1st doses for 5 - 10 days (IDSA)
Cephalexin (Keflex®) 1st Endocarditis prophylaxis - 20
Cefaclor (Ceclor®) 2nd mg/kg (max 600 mg) 30 - 60
Cefprozil (Cefzil®) 2nd minutes before procedure
Cefuroxime (Ceftin®) 2nd (penicillin allergic) (AHA)
Cefdinir (Omnicef®) 3rd Impetigo - 20 mg/kg/day (max
Cefditoren (Spectracef®) 3rd 1600 mg/day) given in 3
Cefixime (Suprax®) 3rd divided doses for 7 days (IDSA)
Cefpodoxime (Vantin®) 3rd Otitis media - 30 - 40
Ceftibuten (Cedax®) 3rd mg/kg/day (max 1800 mg/day)
Ceftriaxone (Rocephin®) 3rd given in 3 divided doses for 5 -
Ceph generations (IV&PO) 10 days (AAP)
Sinusitis - 8 - 12 mg/kg/day
CLINDAMYCIN (CLEOCIN®)
divided into 3 or 4 equal doses
FOSFOMYCIN (MONUROL®)
for a minimum of 10 days. Give
LEFAMULIN (XENLETA®) with Cefixime (Suprax®). See
OXAZOLIDINONES AAP sinusitis recs. (AAP, PI)
MACROLIDES Strep throat - 7 mg/kg/dose
(max 300 mg/dose) three times
NITAZOXANIDE (ALINIA®)
daily for 10 days (IDSA)
NITROFURANTOIN (MACROBID®)
NITROIMIDAZOLES Adults
PENICILLINS Bacterial vaginosis
Clindamycin 2% vaginal
QUINOLONES
cream - one full applicator
RIFAMYCINS (5g) intravaginally at bedtime
SULFONAMIDES for 7 days (CDC)
TETRACYCLINES Clindamycin 2% vaginal
cream (Clindesse®) - one
OPHTHALMIC ANTIBIOTIC TABLE
full applicator (5g) once
OTIC ANTIBIOTIC TABLE intravaginally at any time of
the day (PI)
Clindamycin oral - 300 mg
twice a day for 7 days (CDC)

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Clindamycin vaginal
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suppository LOGIN
(Cleocin®) - 100
mg intravaginally once at
ANTIBIOTIC CHARTbedtime for 3 days (CDC)
TOP Bite, animal - Clindamycin -
300 mg three times a day +
ACRONYMS
Cefuroxime (Ceftin®) - 500
CEPHALOSPORINS
mg twice a day; OR
Cefadroxil (Duricef®) 1st Levofloxacin (Levaquin®) -
Cephalexin (Keflex®) 1st 750 mg once daily; OR
Cefaclor (Ceclor®) 2nd Sulfamethoxazole-
Cefprozil (Cefzil®) 2nd trimethoprim - 800/160 twice a
Cefuroxime (Ceftin®) 2nd day (IDSA)
Cefdinir (Omnicef®) 3rd Cellulitis (MRSA coverage) -
Cefditoren (Spectracef®) 3rd 300 - 450 mg four times a day
Cefixime (Suprax®) 3rd for 5 - 10 days (IDSA)
Cefpodoxime (Vantin®) 3rd Diabetic foot ulcer (mild) - 300 -
Ceftibuten (Cedax®) 3rd 450 mg four times a day for 7 -
Ceftriaxone (Rocephin®) 3rd 14 days (IDSA)
Ceph generations (IV&PO) Diabetic foot ulcer (moderate) -
Clindamycin 300 - 450 mg four
CLINDAMYCIN (CLEOCIN®)
times a day +
FOSFOMYCIN (MONUROL®)
Ciprofloxacin 500 mg twice a
LEFAMULIN (XENLETA®) day for 7 - 14 days; OR
OXAZOLIDINONES Levofloxacin 750 mg once
MACROLIDES daily for 7 - 14 days (IDSA)
Endocarditis prophylaxis - 600
NITAZOXANIDE (ALINIA®)
mg 30 - 60 minutes before
NITROFURANTOIN (MACROBID®)
procedure (penicillin allergic)
NITROIMIDAZOLES (AHA)
PENICILLINS Hidradenitis suppurativa
Clindamycin 300 mg twice a
QUINOLONES
day + Rifampin 600 mg once
RIFAMYCINS daily for 10 weeks [Based on
SULFONAMIDES PMID 19590173]
TETRACYCLINES Topical clindamycin applied
twice a day (CTE)
OPHTHALMIC ANTIBIOTIC TABLE
Impetigo - 300 - 400 mg four
OTIC ANTIBIOTIC TABLE times a day for 7 days (IDSA)
Pseudofolliculitis barbae -
Benzoyl peroxide + topical
clindamycin applied twice a day
(CTE)

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Pulpitis (toothache) - 300 mg

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four times a day for 3 LOGIN
- 7 days
(ADA)
ANTIBIOTIC CHART
Strep throat - 300 mg three
TOP times a day for 10 days (IDSA)

ACRONYMS
Other
CEPHALOSPORINS
Cefadroxil (Duricef®) 1st May take without regard to food
Cephalexin (Keflex®) 1st Liver disease - dose
Cefaclor (Ceclor®) 2nd adjustment not likely necessary
Cefprozil (Cefzil®) 2nd Kidney disease - no dose
Cefuroxime (Ceftin®) 2nd adjustment necessary
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd
Cefpodoxime (Vantin®) 3rd
Fosfomycin
Ceftibuten (Cedax®) 3rd
Monurol®
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO)
Dosage forms
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®) Powder
3 gram packet ($$)
LEFAMULIN (XENLETA®)
OXAZOLIDINONES
Dosing
MACROLIDES
NITAZOXANIDE (ALINIA®) Adults
Urinary tract infection - 3 gram
NITROFURANTOIN (MACROBID®)
packet one time dose (IDSA,
NITROIMIDAZOLES
PI)
PENICILLINS Urinary tract infection,
QUINOLONES prophylaxis - 3 gram packet
every 10 days (CTE)
RIFAMYCINS
SULFONAMIDES Other
TETRACYCLINES
May take without regard to food
OPHTHALMIC ANTIBIOTIC TABLE
Mix packet with 3 - 4 ounces of
OTIC ANTIBIOTIC TABLE water
Kidney disease - clearance is
decreased. Manufacturer

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makes no specific
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recommendation. LOGIN

ANTIBIOTIC CHART
TOP
ACRONYMS Lefamulin
CEPHALOSPORINS Xenleta™
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st Dosage forms
Cefaclor (Ceclor®) 2nd
Tablet
Cefprozil (Cefzil®) 2nd
600 mg ($$$$)
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd
Dosing
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd Adults (18 years and older)
Cefpodoxime (Vantin®) 3rd Pneumonia, community-
Ceftibuten (Cedax®) 3rd acquired - 600 mg every 12
Ceftriaxone (Rocephin®) 3rd hours for 5 days (PI)
Ceph generations (IV&PO)
CLINDAMYCIN (CLEOCIN®) Other
FOSFOMYCIN (MONUROL®)
Take at least 1 hour before a
LEFAMULIN (XENLETA®)
meal or 2 hours after a meal.
OXAZOLIDINONES Food decreases absorption.
MACROLIDES Do not use in pregnant women
NITAZOXANIDE (ALINIA®) Lefamulin is a bacterial
ribosomal RNA inhibitor
NITROFURANTOIN (MACROBID®)
Lefamulin is a sensitive
NITROIMIDAZOLES
CYP3A4 substrate and
PENICILLINS inhibitor. Strong and moderate
QUINOLONES CYP3A4 inducers may
decrease the effectiveness of
RIFAMYCINS
lefamulin. Do not take lefamulin
SULFONAMIDES with strong CYP3A4 inhibitors.
TETRACYCLINES Monitor for adverse effects
when taking with moderate
OPHTHALMIC ANTIBIOTIC TABLE
CYP3A4 inhibitors.
OTIC ANTIBIOTIC TABLE
Lefamulin is a P-glycoprotein
substrate. P-glycoprotein
inducers may decrease the
effectiveness of lefamulin. Do
not take with strong P-

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glycoprotein inhibitors. Monitor

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for adverse LOGIN
effects when taking
with moderate P-glycoprotein
ANTIBIOTIC CHART
inhibitors.
TOP Lefamulin can prolong the QT
interval. Avoid use in patients
ACRONYMS
with prolonged QT syndrome
CEPHALOSPORINS
and in those taking concomitant
Cefadroxil (Duricef®) 1st medications that can prolong
Cephalexin (Keflex®) 1st the QT interval.
Cefaclor (Ceclor®) 2nd Lefamulin is contraindicated
Cefprozil (Cefzil®) 2nd with sensitive CYP3A4
Cefuroxime (Ceftin®) 2nd substrates that prolong the QT
Cefdinir (Omnicef®) 3rd interval (e.g. pimozide)
Cefditoren (Spectracef®) 3rd Liver disease
Cefixime (Suprax®) 3rd Mild (Child-Pugh A): no dose
Cefpodoxime (Vantin®) 3rd adjustment necessary
Ceftibuten (Cedax®) 3rd Moderate to severe (Child-
Ceftriaxone (Rocephin®) 3rd Pugh B/C): has not been
Ceph generations (IV&PO) evaluated. Not
recommended.
CLINDAMYCIN (CLEOCIN®)
Kidney disease - no dose
FOSFOMYCIN (MONUROL®)
adjustment necessary
LEFAMULIN (XENLETA®)
OXAZOLIDINONES
Studies
MACROLIDES
Lefamulin vs Moxifloxacin in
NITAZOXANIDE (ALINIA®)
Adults with Community-
NITROFURANTOIN (MACROBID®)
acquired Pneumonia, JAMA
NITROIMIDAZOLES (2019) [PubMed abstract]
PENICILLINS
QUINOLONES
RIFAMYCINS
SULFONAMIDES Linezolid
Zyvox®
TETRACYCLINES
OPHTHALMIC ANTIBIOTIC TABLE Dosage forms
OTIC ANTIBIOTIC TABLE
Tablet
600 mg ($)

Suspension

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23/10/2024, 20:43 Antibiotic chart

100 mg/5 ml ($$$$)

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Dosing
ANTIBIOTIC CHART
TOP Pediatric
Cellulitis (MRSA coverage)
ACRONYMS
< 5 years old - 10
CEPHALOSPORINS
mg/kg/dose every 8 hours
Cefadroxil (Duricef®) 1st for 5 - 10 days (IDSA, PI)
Cephalexin (Keflex®) 1st 5 - 11 years old - 10
Cefaclor (Ceclor®) 2nd mg/kg/dose (max 600
Cefprozil (Cefzil®) 2nd mg/dose) twice a day for 5 -
Cefuroxime (Ceftin®) 2nd 10 days (IDSA, PI)
Cefdinir (Omnicef®) 3rd Pneumonia, community-
Cefditoren (Spectracef®) 3rd acquired
Cefixime (Suprax®) 3rd < 12 years old - 30
Cefpodoxime (Vantin®) 3rd mg/kg/day given in 3 divided
Ceftibuten (Cedax®) 3rd doses for 7 - 10 days (IDSA)
Ceftriaxone (Rocephin®) 3rd ≥ 12 years old - 20
Ceph generations (IV&PO) mg/kg/day (max 1200
mg/day) given in 2 divided
CLINDAMYCIN (CLEOCIN®)
doses for 7 - 10 days (IDSA)
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Adults (12 years and older)
OXAZOLIDINONES Cellulitis (MRSA coverage) -
MACROLIDES 600 mg twice a day for 5 - 10
days (IDSA)
NITAZOXANIDE (ALINIA®)
Diabetic foot ulcer (moderate,
NITROFURANTOIN (MACROBID®)
MRSA coverage) - 400 - 600
NITROIMIDAZOLES mg twice a day for 7 - 14 days
PENICILLINS (IDSA)
Pneumonia, community-
QUINOLONES
acquired - 600 mg twice a day
RIFAMYCINS for 10 - 14 days (PI)
SULFONAMIDES
TETRACYCLINES Other

OPHTHALMIC ANTIBIOTIC TABLE May take without regard to food

OTIC ANTIBIOTIC TABLE Linezolid is a bacterial
ribosomal RNA inhibitor
Linezolid is a reversible,
nonselective MAO inhibitor. Do

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23/10/2024, 20:43 Antibiotic chart

not take within 2 weeks of other

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MAO inhibitors.
Linezolid may increase the
ANTIBIOTIC CHART
pressor effect of adrenergic
TOP agents including
pseudoephedrine and
ACRONYMS
phenylpropanolamine. Foods
CEPHALOSPORINS
containing tyramine should also
Cefadroxil (Duricef®) 1st be avoided in large quantities
Cephalexin (Keflex®) 1st (e.g. aged cheeses, fermented
Cefaclor (Ceclor®) 2nd or air-dried meats, sauerkraut,
Cefprozil (Cefzil®) 2nd soy sauce, tap beers, and red
Cefuroxime (Ceftin®) 2nd wines)
Cefdinir (Omnicef®) 3rd Linezolid has been shown to
Cefditoren (Spectracef®) 3rd increase the risk of serotonin
Cefixime (Suprax®) 3rd syndrome. Do not use with
Cefpodoxime (Vantin®) 3rd other serotonergic agents
Ceftibuten (Cedax®) 3rd unless no other options are
Ceftriaxone (Rocephin®) 3rd available. If concomitant
Ceph generations (IV&PO) therapy is necessary, monitor
for symptoms of serotonin
CLINDAMYCIN (CLEOCIN®)
syndrome for two weeks (five
FOSFOMYCIN (MONUROL®)
weeks if fluoxetine was taken)
LEFAMULIN (XENLETA®) or until 24 hours after the last
OXAZOLIDINONES dose of linezolid, whichever
MACROLIDES comes first.
Postmarketing cases of the
NITAZOXANIDE (ALINIA®)
syndrome of inappropriate
NITROFURANTOIN (MACROBID®)
antidiuretic hormone secretion
NITROIMIDAZOLES (SIADH) have been reported in
PENICILLINS patients receiving linezolid.
Monitor sodium levels during
QUINOLONES
linezolid therapy in patients
RIFAMYCINS who are at increased risk of
SULFONAMIDES SIADH (e.g. elderly, taking
TETRACYCLINES diuretics).
Liver disease
OPHTHALMIC ANTIBIOTIC TABLE
Mild to moderate (Child-
OTIC ANTIBIOTIC TABLE Pugh A/B): no dose
adjustment necessary
Severe (Child-Pugh C): has
not been evaluated

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23/10/2024, 20:43 Antibiotic chart

Kidney disease - no dose

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adjustment necessaryLOGIN

ANTIBIOTIC CHART
Studies
TOP
Linezolid susceptibility testing
ACRONYMS
in 2014 [PubMed abstract] -
CEPHALOSPORINS 6,865 Gram-positive pathogens
Cefadroxil (Duricef®) 1st from 36 states collected in
Cephalexin (Keflex®) 1st 2014 were tested for
Cefaclor (Ceclor®) 2nd susceptibility to linezolid.
Cefprozil (Cefzil®) 2nd Linezolid demonstrated
Cefuroxime (Ceftin®) 2nd excellent activity and a
Cefdinir (Omnicef®) 3rd sustained susceptibility rate of
Cefditoren (Spectracef®) 3rd 99.78% overall.
Cefixime (Suprax®) 3rd
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd
Ceftriaxone (Rocephin®) 3rd Tedizolid
Ceph generations (IV&PO)
Sivextro®
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®) Dosage forms
LEFAMULIN (XENLETA®)
Tablet
OXAZOLIDINONES
200 mg ($$$$)
MACROLIDES
NITAZOXANIDE (ALINIA®) Dosing
NITROFURANTOIN (MACROBID®)
Adults and children (12 years and
NITROIMIDAZOLES
older)
PENICILLINS Cellulitis (MRSA coverage) -
QUINOLONES 200 mg once daily for 6 days
(PI)
RIFAMYCINS
SULFONAMIDES Other
TETRACYCLINES
May take without regard to food
OPHTHALMIC ANTIBIOTIC TABLE
For a missed dose, take as
OTIC ANTIBIOTIC TABLE soon as possible anytime up to
8 hours prior to the next
scheduled dose. If less than 8
hours remain before the next

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dose, wait until next scheduled

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Tedizolid is a bacterial
ANTIBIOTIC CHART
ribosomal RNA inhibitor
TOP Tedizolid is a reversible MAO
inhibitor. Do not take within 2
ACRONYMS
weeks of other MAO inhibitors.
CEPHALOSPORINS
Tedizolid is a BCRP inhibitor
Cefadroxil (Duricef®) 1st and may increase exposure to
Cephalexin (Keflex®) 1st BCRP substrates
Cefaclor (Ceclor®) 2nd May increase the pressor effect
Cefprozil (Cefzil®) 2nd of adrenergic agents including
Cefuroxime (Ceftin®) 2nd pseudoephedrine and
Cefdinir (Omnicef®) 3rd phenylpropanolamine. Foods
Cefditoren (Spectracef®) 3rd containing tyramine should also
Cefixime (Suprax®) 3rd be avoided in large quantities
Cefpodoxime (Vantin®) 3rd (e.g. aged cheeses, fermented
Ceftibuten (Cedax®) 3rd or air-dried meats, sauerkraut,
Ceftriaxone (Rocephin®) 3rd soy sauce, tap beers, and red
Ceph generations (IV&PO) wines)
May increase the risk of
CLINDAMYCIN (CLEOCIN®)
serotonin syndrome. Use
FOSFOMYCIN (MONUROL®)
caution when taken with
LEFAMULIN (XENLETA®) antidepressants and other
OXAZOLIDINONES serotonergic drugs. A
MACROLIDES retrospective cohort study
(N=479) among hospitalized
NITAZOXANIDE (ALINIA®)
patients receiving tedizolid with
NITROFURANTOIN (MACROBID®)
other serotonergic medications
NITROIMIDAZOLES found that the incidence of
PENICILLINS clinically suspected serotonin
syndrome was 0.4%. [PMID
QUINOLONES
39235251]
RIFAMYCINS Liver disease - no dose
SULFONAMIDES adjustment necessary
TETRACYCLINES Kidney disease - no dose
adjustment necessary
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE

Azithromycin
Zithromax®

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Dosage forms
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Tablet
ANTIBIOTIC CHART
250 mg ($)
500 mg ($)
TOP
600 mg ($)
ACRONYMS
CEPHALOSPORINS Suspension
Cefadroxil (Duricef®) 1st 100 mg/5 ml ($)
Cephalexin (Keflex®) 1st 200 mg/5 ml ($)
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd Powder, one packet
Cefuroxime (Ceftin®) 2nd 1000 mg ($)
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd Suspension, extended-release (Zmax®)
Cefixime (Suprax®) 3rd 2 grams/bottle ($$$)
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd Ophthalmic
Ceftriaxone (Rocephin®) 3rd See conjunctivitis
Ceph generations (IV&PO)
CLINDAMYCIN (CLEOCIN®) Dosing

FOSFOMYCIN (MONUROL®)
Pediatric (0 - 5 months)
LEFAMULIN (XENLETA®) Bordetella pertussis (treatment
OXAZOLIDINONES or postexposure prophylaxis)
MACROLIDES < 1 month - 10 mg/kg/day
given once daily for 5 days
NITAZOXANIDE (ALINIA®)
(CDC)
NITROFURANTOIN (MACROBID®)
1 - 5 months - 10 mg/kg/day
NITROIMIDAZOLES given once daily for 5 days
PENICILLINS (CDC)

QUINOLONES
Pediatric (6 months to 12 years)
RIFAMYCINS Bordetella pertussis (treatment
SULFONAMIDES or postexposure prophylaxis) -
TETRACYCLINES 10 mg/kg given as a single
dose on day 1, then
OPHTHALMIC ANTIBIOTIC TABLE
5 mg/kg/day (max 500 mg)
OTIC ANTIBIOTIC TABLE given once daily on days 2 - 5
(CDC)
Campylobacter - 10 mg/kg/day
(max 500 mg/day) given once
daily for 3 - 5 days (CTE)

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Cat scratch disease

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kg - 10 mg/kg LOGIN
(max 500
mg) on Day 1 followed by 5
ANTIBIOTIC CHARTmg/kg/day (max 250
TOP mg/day) on Days 2 - 5
> 45 kg - 500 mg on Day 1
ACRONYMS
followed by 250 mg once
CEPHALOSPORINS
daily on Days 2 - 5 (IDSA)
Cefadroxil (Duricef®) 1st E. coli, enterotoxigenic - 10
Cephalexin (Keflex®) 1st mg/kg/day (max 500 mg/day)
Cefaclor (Ceclor®) 2nd given once daily for 3 days
Cefprozil (Cefzil®) 2nd (CTE)
Cefuroxime (Ceftin®) 2nd Endocarditis prophylaxis -15
Cefdinir (Omnicef®) 3rd mg/kg (max 500 mg) 30 - 60
Cefditoren (Spectracef®) 3rd minutes before procedure
Cefixime (Suprax®) 3rd (penicillin allergic) (AHA)
Cefpodoxime (Vantin®) 3rd Pneumonia, community-
Ceftibuten (Cedax®) 3rd acquired, atypical - 10 mg/kg
Ceftriaxone (Rocephin®) 3rd (max 500 mg) on Day 1
Ceph generations (IV&PO) followed by 5 mg/kg/day (max
250 mg/day) given once daily
CLINDAMYCIN (CLEOCIN®)
on Days 2 - 5 (IDSA)
FOSFOMYCIN (MONUROL®)
Salmonella (nontyphoidal) - 20
LEFAMULIN (XENLETA®) mg/kg/day (max 500 mg/day)
OXAZOLIDINONES given once daily for 7 days
MACROLIDES (CTE)
Shigella - 10 mg/kg/day (max
NITAZOXANIDE (ALINIA®)
500 mg/day) given once daily
NITROFURANTOIN (MACROBID®)
for 3 days (CTE)
NITROIMIDAZOLES Strep throat - 12 mg/kg/day
PENICILLINS (max 500 mg/day) given once
daily for 5 days (IDSA)
QUINOLONES
Vibrio vulnificus - 10 mg/kg/day
RIFAMYCINS (max 500 mg/day) given once
SULFONAMIDES daily for 3 days (CTE)
TETRACYCLINES
Adolescents and Adults
OPHTHALMIC ANTIBIOTIC TABLE
Bordetella pertussis (treatment
OTIC ANTIBIOTIC TABLE or postexposure prophylaxis) -
500 mg on day 1, then 250 mg
once daily on days 2 - 5 (CDC)
Campylobacter - 500 mg once
daily for 3 days (CTE)

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Cat scratch disease - 500 mg

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followed by 250 mg
for 4 additional days (IDSA)
ANTIBIOTIC CHART
Chlamydia - 1000 mg single
TOP dose (CDC)
E. coli, enterotoxigenic - 1000
ACRONYMS
mg given as a single dose
CEPHALOSPORINS
(CTE)
Cefadroxil (Duricef®) 1st Gonorrhea (cervical, urethral,
Cephalexin (Keflex®) 1st rectal, pharyngeal)
Cefaclor (Ceclor®) 2nd Azithromycin 2000 mg single
Cefprozil (Cefzil®) 2nd dose + gemifloxacin 320 mg
Cefuroxime (Ceftin®) 2nd single dose [Based on PMID
Cefdinir (Omnicef®) 3rd 25031289]
Cefditoren (Spectracef®) 3rd Azithromycin 2000 mg single
Cefixime (Suprax®) 3rd dose + gentamicin 240 mg
Cefpodoxime (Vantin®) 3rd IM single dose [Based on
Ceftibuten (Cedax®) 3rd PMID 25031289]
Ceftriaxone (Rocephin®) 3rd Endocarditis prophylaxis - 500
Ceph generations (IV&PO) mg 30 - 60 minutes before
procedure (penicillin allergic)
CLINDAMYCIN (CLEOCIN®)
(AHA)
FOSFOMYCIN (MONUROL®)
Mycoplasma genitalium
LEFAMULIN (XENLETA®) (macrolide sensitive) -
OXAZOLIDINONES Doxycycline 100 mg twice daily
MACROLIDES for 7 days, followed by
azithromycin 1 gram initial
NITAZOXANIDE (ALINIA®)
dose, followed by 500 mg once
NITROFURANTOIN (MACROBID®)
daily for 3 additional days (2.5
NITROIMIDAZOLES grams total) (CDC)
PENICILLINS Pneumonia, community-
acquired
QUINOLONES
Azithromycin - 500 mg on
RIFAMYCINS Day 1 followed by 250 mg
SULFONAMIDES once daily on Days 2 - 5
TETRACYCLINES (IDSA, PI)
Extended-release (Zmax®) -
OPHTHALMIC ANTIBIOTIC TABLE
2000 mg one time dose (PI)
OTIC ANTIBIOTIC TABLE Prostatitis, chronic - 500 mg
once daily for 4 - 6 weeks
(CTE)
Pulpitis (toothache) - 500 mg
on day 1 followed by 250 mg

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23/10/2024, 20:43 Antibiotic chart

for 4 additional days (ADA)

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Salmonella LOGIN
(nontyphoidal) -
500 mg once daily for 7 days
ANTIBIOTIC CHART
(CTE)
TOP Shigella - 500 mg once daily for
3 days (CTE)
ACRONYMS
Strep throat - 500 mg once
CEPHALOSPORINS
daily for 5 days (IDSA)
Cefadroxil (Duricef®) 1st Syphilis (primary and
Cephalexin (Keflex®) 1st secondary, pen-allergic) - 2000
Cefaclor (Ceclor®) 2nd mg single dose (CDC)
Cefprozil (Cefzil®) 2nd Vibrio vulnificus - 500 mg once
Cefuroxime (Ceftin®) 2nd daily for 3 days (CTE)
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd Other
Cefixime (Suprax®) 3rd
Cefpodoxime (Vantin®) 3rd May take without regard to food
Do not take with aluminum or
Ceftibuten (Cedax®) 3rd
magnesium antacids
Ceftriaxone (Rocephin®) 3rd
Azithromycin may cause QT
Ceph generations (IV&PO)
interval prolongation. Use
CLINDAMYCIN (CLEOCIN®)
caution in susceptible patients.
FOSFOMYCIN (MONUROL®) Liver disease: has not been
LEFAMULIN (XENLETA®) studied. Manufacturer makes
OXAZOLIDINONES no recommendation.
Azithromycin-induced
MACROLIDES
hepatotoxicity has occurred in
NITAZOXANIDE (ALINIA®)
some patients.
NITROFURANTOIN (MACROBID®) Kidney disease
NITROIMIDAZOLES CrCl > 10 ml/min: no dose
PENICILLINS adjustment necessary
CrCl < 10 ml/min: use
QUINOLONES
caution
RIFAMYCINS
SULFONAMIDES Studies

TETRACYCLINES
Macrolide use during
OPHTHALMIC ANTIBIOTIC TABLE pregnancy and adverse child
OTIC ANTIBIOTIC TABLE outcomes in the UK, BMJ
(2020) [PubMed abstract]
Macrolide use in pregnancy
and risk of birth defects,

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Pharmacoepidemiol Drug Saf

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(2015) [PubMed LOGIN
abstract]

ANTIBIOTIC CHART
TOP
ACRONYMS Clarithromycin
CEPHALOSPORINS Biaxin®
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st Dosage forms
Cefaclor (Ceclor®) 2nd
Tablet
Cefprozil (Cefzil®) 2nd
250 mg ($)
Cefuroxime (Ceftin®) 2nd
500 mg ($)
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd
Suspension
Cefixime (Suprax®) 3rd
125 mg/5 ml ($)
Cefpodoxime (Vantin®) 3rd
250 mg/5 ml ($$)
Ceftibuten (Cedax®) 3rd
Ceftriaxone (Rocephin®) 3rd
Tablet, extended-release (Biaxin XL®)
Ceph generations (IV&PO)
500 mg ($)
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®) Dosing
LEFAMULIN (XENLETA®)
OXAZOLIDINONES Pediatric (0 - 5 months)
Bordetella pertussis (treatment
MACROLIDES
or postexposure prophylaxis)
NITAZOXANIDE (ALINIA®) < 1 month - Not
NITROFURANTOIN (MACROBID®) recommended. Use
NITROIMIDAZOLES azithromycin. (CDC)
1 - 5 months - 15 mg/kg/day
PENICILLINS
given in 2 divided doses for
QUINOLONES 7 days (CDC)
RIFAMYCINS
Pediatric (≥ 6 months and
SULFONAMIDES
children)
TETRACYCLINES Bordetella pertussis (treatment
OPHTHALMIC ANTIBIOTIC TABLE or postexposure prophylaxis) -
OTIC ANTIBIOTIC TABLE 15 mg/kg/day (max 1000
mg/day) given in 2 divided
doses for 7 days (CDC)
Endocarditis prophylaxis - 15
mg/kg (max 500 mg) 30 - 60

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23/10/2024, 20:43 Antibiotic chart

minutes before procedure

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(penicillin LOGIN
allergic) (AHA)
H. pylori - Clarithromycin - 20
ANTIBIOTIC CHART
mg/kg/day (max 1000 mg/day)
TOP given in 2 divided doses +
Amoxicillin - 50 mg/kg/day
ACRONYMS
(max 2000 mg/day) given in 2
CEPHALOSPORINS
divided doses +
Cefadroxil (Duricef®) 1st Proton Pump Inhibitor (PPI)
Cephalexin (Keflex®) 1st (CTE)
Cefaclor (Ceclor®) 2nd DURATION: 10 - 14 days
Cefprozil (Cefzil®) 2nd H. pylori, sequential therapy -
Cefuroxime (Ceftin®) 2nd see H. pylori treatment
Cefdinir (Omnicef®) 3rd Pneumonia, community-
Cefditoren (Spectracef®) 3rd acquired, atypical - 15
Cefixime (Suprax®) 3rd mg/kg/day (max 1000 mg/day)
Cefpodoxime (Vantin®) 3rd given in 2 divided doses for 7 -
Ceftibuten (Cedax®) 3rd 10 days (IDSA)
Ceftriaxone (Rocephin®) 3rd Strep throat - 15 mg/kg/day
Ceph generations (IV&PO) (max 500 mg/day) given in 2
divided doses for 10 days
CLINDAMYCIN (CLEOCIN®)
(IDSA)
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Adults
OXAZOLIDINONES Bordetella pertussis (treatment
MACROLIDES or postexposure prophylaxis) -
500 mg twice a day for 7 days
NITAZOXANIDE (ALINIA®)
(CDC)
NITROFURANTOIN (MACROBID®)
Endocarditis prophylaxis - 500
NITROIMIDAZOLES mg 30 - 60 minutes before
PENICILLINS procedure (penicillin allergic)
(AHA)
QUINOLONES
H. pylori treatment regimens
RIFAMYCINS Pneumonia, community-
SULFONAMIDES acquired
TETRACYCLINES Standard-release: 250 - 500
mg twice a day for 7 - 14
OPHTHALMIC ANTIBIOTIC TABLE
days (IDSA, PI)
OTIC ANTIBIOTIC TABLE Extended-release: 1000 mg
once daily for 7 days (IDSA,
PI)
Prostatitis, chronic - 500 mg
twice a day for 4 - 6 weeks

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23/10/2024, 20:43 Antibiotic chart

(CTE)
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Standard-release: 500 mg
ANTIBIOTIC CHARTtwice a day for 14 days (PI)
TOP Extended-release: 1000 mg
once daily for 14 days (PI)
ACRONYMS
Skin infections - 250 mg twice a
CEPHALOSPORINS
day for 7 - 14 days (PI)
Cefadroxil (Duricef®) 1st Strep throat - 250 mg twice a
Cephalexin (Keflex®) 1st day for 10 days (IDSA)
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd Other
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd Standard-release tablet and
Cefditoren (Spectracef®) 3rd suspension may be taken
Cefixime (Suprax®) 3rd without regard to food.
Cefpodoxime (Vantin®) 3rd Extended-release tablets
Ceftibuten (Cedax®) 3rd should be taken with food.
Clarithromycin is a CYP3A4
Ceftriaxone (Rocephin®) 3rd
strong inhibitor and is
Ceph generations (IV&PO)
contraindicated with a number
CLINDAMYCIN (CLEOCIN®)
of CYP3A4 sensitive
FOSFOMYCIN (MONUROL®) substrates. See Biaxin PI for
LEFAMULIN (XENLETA®) more.
OXAZOLIDINONES Clarithromycin is not
recommended in patients with
MACROLIDES
heart disease because of a
NITAZOXANIDE (ALINIA®)
potential increased risk of heart
NITROFURANTOIN (MACROBID®) problems or death that can
NITROIMIDAZOLES occur years later
PENICILLINS Clarithromycin is not
recommended in pregnancy
QUINOLONES
Liver disease - no dose
RIFAMYCINS adjustment necessary
SULFONAMIDES Kidney disease
CrCl < 30 ml/min: - reduce
TETRACYCLINES
dose by 50%
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE Studies

Macrolide use during

pregnancy and adverse child
outcomes in the UK, BMJ
(2020) [PubMed abstract]
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23/10/2024, 20:43 Antibiotic chart

Macrolide use in pregnancy

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of birth defects,
Pharmacoepidemiol Drug Saf
ANTIBIOTIC CHART
(2015) [PubMed abstract]
TOP
ACRONYMS
CEPHALOSPORINS
Cefadroxil (Duricef®) 1st Erythromycin
Cephalexin (Keflex®) 1st Eryc®, ERY-tab®, E.E.S.®,
Cefaclor (Ceclor®) 2nd Eryped®, PCE®
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd Erythromycin base
Cefdinir (Omnicef®) 3rd
Tablet
Cefditoren (Spectracef®) 3rd
250 mg ($$-$$$)
Cefixime (Suprax®) 3rd
500 mg ($$-$$$)
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd
Capsule, enteric-coated (Eryc®)
Ceftriaxone (Rocephin®) 3rd
250 mg ($$)
Ceph generations (IV&PO)
CLINDAMYCIN (CLEOCIN®) Tablet, delayed-release (Ery-tab®)
FOSFOMYCIN (MONUROL®) 250 mg ($-$$)
LEFAMULIN (XENLETA®) 333 mg ($$)
OXAZOLIDINONES 500 mg ($$-$$$)

MACROLIDES
Tablet, enteric-coated (PCE®)
NITAZOXANIDE (ALINIA®)
333 mg ($$$$)
NITROFURANTOIN (MACROBID®) 500 mg ($$$$)
NITROIMIDAZOLES
PENICILLINS Ophthalmic
See conjunctivitis
QUINOLONES
RIFAMYCINS Topical
SULFONAMIDES See topical derm meds
TETRACYCLINES
OPHTHALMIC ANTIBIOTIC TABLE Erythromycin ethylsuccinate

OTIC ANTIBIOTIC TABLE Tablet (E.E.S.®)

400 mg ($$$$)

Suspension (E.E.S.®, Eryped®)

200 mg/5 ml ($$-$$$)

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23/10/2024, 20:43 Antibiotic chart

400 mg/5 ml ($$$$)

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Dosing
ANTIBIOTIC CHART
TOP Pediatric (0 - 5 months)
Bordetella pertussis (treatment
ACRONYMS
or postexposure prophylaxis)
CEPHALOSPORINS
< 1 month: 40 - 50
Cefadroxil (Duricef®) 1st mg/kg/day given in 4 divided
Cephalexin (Keflex®) 1st doses for 14 days. Dosing is
Cefaclor (Ceclor®) 2nd for erythromycin base.
Cefprozil (Cefzil®) 2nd Azithromycin is the preferred
Cefuroxime (Ceftin®) 2nd agent in this age group.
Cefdinir (Omnicef®) 3rd (CDC)
Cefditoren (Spectracef®) 3rd 1 - 5 months: 40 - 50
Cefixime (Suprax®) 3rd mg/kg/day given in 4 divided
Cefpodoxime (Vantin®) 3rd doses for 14 days. Dosing is
Ceftibuten (Cedax®) 3rd for erythromycin base.
Ceftriaxone (Rocephin®) 3rd (CDC)
Ceph generations (IV&PO)
Pediatric (≥ 6 months and
CLINDAMYCIN (CLEOCIN®)
children)
FOSFOMYCIN (MONUROL®)
Bordetella pertussis (treatment
LEFAMULIN (XENLETA®) or postexposure prophylaxis)
OXAZOLIDINONES Erythromycin base:
MACROLIDES 40 - 50 mg/kg/day (max
2000 mg/day) given in 4
NITAZOXANIDE (ALINIA®)
divided doses for 14 days
NITROFURANTOIN (MACROBID®)
(CDC)
NITROIMIDAZOLES Campylobacter
PENICILLINS Erythromycin base - 30
mg/kg/day given in 2 - 4
QUINOLONES
divided doses for 3 - 5 days
RIFAMYCINS (CTE)
SULFONAMIDES Impetigo
TETRACYCLINES Erythromycin ethylsuccinate
- 40 mg/kg/day (max 1600
OPHTHALMIC ANTIBIOTIC TABLE
mg/day) given in 3 - 4
OTIC ANTIBIOTIC TABLE divided doses for 7 days
(IDSA)
Pneumonia, community-
acquired, atypical

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23/10/2024, 20:43 Antibiotic chart

Erythromycin ethylsuccinate
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- 40 mg/kg/day LOGIN
1600
mg/day) given in 4 divided
ANTIBIOTIC CHARTdoses for 7 - 10 days (IDSA)
TOP
Adolescents and adults
ACRONYMS
Acne
CEPHALOSPORINS
Erythromycin base: 250 -
Cefadroxil (Duricef®) 1st 500 mg once daily or 250 -
Cephalexin (Keflex®) 1st 500 mg twice a day (AAP)
Cefaclor (Ceclor®) 2nd Bordetella pertussis (treatment
Cefprozil (Cefzil®) 2nd or postexposure prophylaxis)
Cefuroxime (Ceftin®) 2nd Erythromycin base - 500 mg
Cefdinir (Omnicef®) 3rd four times a day for 14 days
Cefditoren (Spectracef®) 3rd (CDC)
Cefixime (Suprax®) 3rd Campylobacter
Cefpodoxime (Vantin®) 3rd Erythromycin base - 500 mg
Ceftibuten (Cedax®) 3rd two to four times a day for 3
Ceftriaxone (Rocephin®) 3rd - 5 days (IDSA/CTE)
Ceph generations (IV&PO) Chlamydia
Erythromycin base - 500 mg
CLINDAMYCIN (CLEOCIN®)
four times a day for 7 days
FOSFOMYCIN (MONUROL®)
(CDC)
LEFAMULIN (XENLETA®) Erythromycin ethylsuccinate
OXAZOLIDINONES - 800 mg four times a day for
MACROLIDES 7 days (CDC)
Impetigo
NITAZOXANIDE (ALINIA®)
Erythromycin base - 250 mg
NITROFURANTOIN (MACROBID®)
four times a day for 7 days
NITROIMIDAZOLES (IDSA)
PENICILLINS Erythromycin ethylsuccinate
- 400 mg four times a day for
QUINOLONES
7 days (IDSA)
RIFAMYCINS Pneumonia, community-
SULFONAMIDES acquired
TETRACYCLINES Erythromycin base - 500 mg
four times a day or 1000 mg
OPHTHALMIC ANTIBIOTIC TABLE
twice a day for 7 - 14 days
OTIC ANTIBIOTIC TABLE (CTE) [2]
Erythromycin ethylsuccinate
- 800 mg four times a day or
1600 mg twice a day for 7 -
14 days

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23/10/2024, 20:43 Antibiotic chart

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May take without regard to food
ANTIBIOTIC CHART
400 mg of erythromycin
TOP ethylsuccinate is equivalent to
ACRONYMS 250 mg of erythromycin base or
stearate
CEPHALOSPORINS
Erythromycin is a Moderate
Cefadroxil (Duricef®) 1st
CYP3A4 inhibitor
Cephalexin (Keflex®) 1st Erythromycin is contraindicated
Cefaclor (Ceclor®) 2nd with lovastatin and simvastatin
Cefprozil (Cefzil®) 2nd Liver disease - use caution.
Cefuroxime (Ceftin®) 2nd Manufacturer makes no
Cefdinir (Omnicef®) 3rd specific recommendation.
Cefditoren (Spectracef®) 3rd Kidney disease - erythromycin
Cefixime (Suprax®) 3rd is mostly excreted in the bile.
Cefpodoxime (Vantin®) 3rd Manufacturer makes no
Ceftibuten (Cedax®) 3rd specific recommendation.
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO) Studies
CLINDAMYCIN (CLEOCIN®)
Macrolide use during
FOSFOMYCIN (MONUROL®)
pregnancy and adverse child
LEFAMULIN (XENLETA®) outcomes in the UK, BMJ
OXAZOLIDINONES (2020) [PubMed abstract]
MACROLIDES Macrolide use in pregnancy
and risk of birth defects,
NITAZOXANIDE (ALINIA®)
Pharmacoepidemiol Drug Saf
NITROFURANTOIN (MACROBID®)
(2015) [PubMed abstract]
NITROIMIDAZOLES
PENICILLINS
QUINOLONES
RIFAMYCINS Fidaxomicin
SULFONAMIDES Dificid®

TETRACYCLINES
Dosage forms
OPHTHALMIC ANTIBIOTIC TABLE
Tablet
OTIC ANTIBIOTIC TABLE
200 mg ($$$$)

Granules for oral suspension

40 mg/ml ($$$$)

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23/10/2024, 20:43 Antibiotic chart

One bottle contains 136 ml after

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reconstitution LOGIN

ANTIBIOTIC CHART
Dosing
TOP
Pediatric (≥ 6 months old)
ACRONYMS
Clostridium difficile
CEPHALOSPORINS
Weight 8.8 lbs (4 kg) to 15.3
Cefadroxil (Duricef®) 1st lbs (6.9 kg): 80 mg twice
Cephalexin (Keflex®) 1st daily for 10 days
Cefaclor (Ceclor®) 2nd Weight 15.4 lbs (7 kg) to
Cefprozil (Cefzil®) 2nd 19.7 lbs (8.9 kg): 120 mg
Cefuroxime (Ceftin®) 2nd twice daily for 10 days
Cefdinir (Omnicef®) 3rd Weight 19.8 lbs (9 kg) to
Cefditoren (Spectracef®) 3rd 27.4 lbs (12.4 kg): 160 mg
Cefixime (Suprax®) 3rd twice daily for 10 days
Cefpodoxime (Vantin®) 3rd Weight ≥ 27.5 lbs (12.5 kg):
Ceftibuten (Cedax®) 3rd 200 mg twice daily for 10
Ceftriaxone (Rocephin®) 3rd days (PI)
Ceph generations (IV&PO)
Adults
CLINDAMYCIN (CLEOCIN®)
Clostridium difficile - 200 mg
FOSFOMYCIN (MONUROL®)
twice a day for 10 days
LEFAMULIN (XENLETA®) (IDSA,PI)
OXAZOLIDINONES
MACROLIDES Other

NITAZOXANIDE (ALINIA®)
May take without regard to food
NITROFURANTOIN (MACROBID®) After granules are
NITROIMIDAZOLES reconstituted, they should be
PENICILLINS refrigerated and are good for
up to 12 days
QUINOLONES
Fidaxomicin undergoes minimal
RIFAMYCINS absorption and should not be
SULFONAMIDES used for systemic infections
Liver disease - fidaxomicin
TETRACYCLINES
undergoes minimal absorption.
OPHTHALMIC ANTIBIOTIC TABLE Liver disease should not affect.
OTIC ANTIBIOTIC TABLE Kidney disease - no dose
adjustment necessary

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NEWSLETTER SUBSCRIBE LOGIN
Alinia®
ANTIBIOTIC CHART
Dosage forms
TOP
ACRONYMS Tablet
CEPHALOSPORINS 500 mg ($$$$)
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st Oral suspension
Cefaclor (Ceclor®) 2nd 100 mg/5 ml ($$$$)
Comes in bottle of 60 ml
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd Dosing
Cefditoren (Spectracef®) 3rd
Pediatric (1 - 11 years old)
Cefixime (Suprax®) 3rd
Cryptosporidium parvum
Cefpodoxime (Vantin®) 3rd
1 - 3 years: 5 ml (100 mg)
Ceftibuten (Cedax®) 3rd
twice a day with food for 3
Ceftriaxone (Rocephin®) 3rd
days [CDC/PI] ($$$$)
Ceph generations (IV&PO)
4 - 11 years: 10 ml (200 mg)
CLINDAMYCIN (CLEOCIN®) twice a day with food for 3
FOSFOMYCIN (MONUROL®) days [CDC/PI] ($$$$)
LEFAMULIN (XENLETA®) Giardia
OXAZOLIDINONES 1 - 3 years: 5 ml (100 mg)
twice a day with food for 3
MACROLIDES
days [CDC/PI] ($$$$)
NITAZOXANIDE (ALINIA®)
4 - 11 years: 10 ml (200 mg)
NITROFURANTOIN (MACROBID®) twice a day with food for 3
NITROIMIDAZOLES days [CDC/PI] ($$$$)
PENICILLINS
Adolescents and Adults (age 12
QUINOLONES
years and older)
RIFAMYCINS Cryptosporidium parvum - 500
SULFONAMIDES mg twice a day for 3 days
TETRACYCLINES [CDC/PI] ($$$$)
Giardia - 500 mg twice a day
OPHTHALMIC ANTIBIOTIC TABLE
for 3 days [CDC/PI] ($$$$)
OTIC ANTIBIOTIC TABLE

Other

Take with food. Food increases

absorption.

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23/10/2024, 20:43 Antibiotic chart

Nitazoxanide is a highly
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protein-bound drug (>LOGIN
99%)
Liver disease - has not been
ANTIBIOTIC CHART
studied. Manufacturer makes
TOP no recommendation.
Kidney disease - has not been
ACRONYMS
studied. Manufacturer makes
CEPHALOSPORINS
no recommendation.
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd Nitrofurantoin
Cefdinir (Omnicef®) 3rd Macrobid®, Macrodantin®,
Cefditoren (Spectracef®) 3rd Furadantin®
Cefixime (Suprax®) 3rd
Cefpodoxime (Vantin®) 3rd Dosage forms
Ceftibuten (Cedax®) 3rd
Macrobid® capsule
Ceftriaxone (Rocephin®) 3rd
Nitrofurantoin monohydrate :
Ceph generations (IV&PO)
Nitrofurantoin macrocrystalline
CLINDAMYCIN (CLEOCIN®) 75 mg : 25 mg ($)
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Macrodantin® capsule
OXAZOLIDINONES Nitrofurantoin macrocrystalline
25 mg ($)
MACROLIDES
50 mg ($)
NITAZOXANIDE (ALINIA®) 100 mg ($)
NITROFURANTOIN (MACROBID®)
NITROIMIDAZOLES Furadantin® suspension
Nitrofurantoin
PENICILLINS
25 mg/5 ml ($$$$)
QUINOLONES
RIFAMYCINS Dosing
SULFONAMIDES
Pediatric (one month and older)
TETRACYCLINES
Urinary tract infection
OPHTHALMIC ANTIBIOTIC TABLE Macrodantin® and
OTIC ANTIBIOTIC TABLE Furadantin® - 5 - 7
mg/kg/day given in 4 divided
doses for 7 days (PI)
Urinary tract infection,
prophylactic

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Macrodantin® and
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Furadantin® - 1 - 2LOGIN
mg/kg/day given once daily
ANTIBIOTIC CHART(CTE)
TOP
Adults
ACRONYMS
Urinary tract infection
CEPHALOSPORINS
Macrobid® - 100 mg twice a
Cefadroxil (Duricef®) 1st day for 5 days (IDSA)
Cephalexin (Keflex®) 1st Macrodantin® - 50 - 100 mg
Cefaclor (Ceclor®) 2nd 4 times a day for 7 days (PI)
Cefprozil (Cefzil®) 2nd Urinary tract infection,
Cefuroxime (Ceftin®) 2nd prophylaxis
Cefdinir (Omnicef®) 3rd Postcoital - 50 - 100 mg one
Cefditoren (Spectracef®) 3rd time postcoital (Macrobid®
Cefixime (Suprax®) 3rd or Macrodantin®) (CTE)
Cefpodoxime (Vantin®) 3rd Continuous - 50 - 100 mg
Ceftibuten (Cedax®) 3rd once daily (Macrobid® or
Ceftriaxone (Rocephin®) 3rd Macrodantin®) (CTE)
Ceph generations (IV&PO)
Other
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®) Take with food
LEFAMULIN (XENLETA®) Do not take with antacids
OXAZOLIDINONES containing magnesium
Nitrofurantoin has been
MACROLIDES
associated with rare cases of
NITAZOXANIDE (ALINIA®)
interstitial lung disease in
NITROFURANTOIN (MACROBID®) patients who took it for ≥ 6
NITROIMIDAZOLES months
PENICILLINS Kidney disease
CrCl < 60 ml/min: - do not
QUINOLONES
use
RIFAMYCINS
SULFONAMIDES
TETRACYCLINES
OPHTHALMIC ANTIBIOTIC TABLE Metronidazole
OTIC ANTIBIOTIC TABLE Flagyl®, Likmez®, Metrogel®,
Vandazole®, Nuvessa®

Dosage forms

Tablet
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250 mg ($)
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($) LOGIN

ANTIBIOTIC CHART
Tablet, extended-release (Flagyl® ER)
TOP 750 mg ($$$$)

ACRONYMS
Capsule
CEPHALOSPORINS
375 mg ($$)
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st
Oral suspension (Likmez®)
Cefaclor (Ceclor®) 2nd
500 mg/5 ml ($$$$)
Cefprozil (Cefzil®) 2nd
Comes in 200 ml bottle
Cefuroxime (Ceftin®) 2nd Store at room temp
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd Vaginal gel (Metrogel-vaginal®)
Cefixime (Suprax®) 3rd 0.75% gel ($)
Cefpodoxime (Vantin®) 3rd Comes in 70 g tube
Ceftibuten (Cedax®) 3rd
Ceftriaxone (Rocephin®) 3rd Vaginal gel (Vandazole®)
Ceph generations (IV&PO) 0.75% gel ($)
CLINDAMYCIN (CLEOCIN®) Comes in 70 g tube
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Vaginal gel (Nuvessa®)
1.3% gel ($$$$)
OXAZOLIDINONES
Comes in single-dose applicator
MACROLIDES
NITAZOXANIDE (ALINIA®) Topical (rosacea)
NITROFURANTOIN (MACROBID®) See topical derm meds
NITROIMIDAZOLES
PENICILLINS Dosing

QUINOLONES Pediatric
RIFAMYCINS Clostridium difficile - 7.5
mg/kg/dose (max 500 mg/dose)
SULFONAMIDES
given 3 - 4 times a day for 10
TETRACYCLINES days (IDSA)
OPHTHALMIC ANTIBIOTIC TABLE Entamoeba histolytica - 35 - 50
OTIC ANTIBIOTIC TABLE mg/kg/day (max 2250 mg/day)
given in 3 divided doses for 10
days (PI)
Giardia - 5 mg/kg/dose (max
250 mg/dose) given 3 times a
day for 7 - 10 days (CTE)
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H. pylori - Metronidazole - 20
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mg/kg/day (max 1000LOGIN
mg/day)
given in 2 divided doses +
ANTIBIOTIC CHART
Amoxicillin - 50 mg/kg/day
TOP (max 2000 mg/day) given in 2
divided doses +
ACRONYMS
Proton Pump Inhibitor (PPI)
CEPHALOSPORINS
(CTE)
Cefadroxil (Duricef®) 1st DURATION: 10 - 14 days
Cephalexin (Keflex®) 1st H. pylori, sequential therapy -
Cefaclor (Ceclor®) 2nd see H. pylori treatment
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd Adults
Cefdinir (Omnicef®) 3rd Bacterial vaginosis
Cefditoren (Spectracef®) 3rd Metronidazole - 500 mg
Cefixime (Suprax®) 3rd twice a day for 7 days (CDC)
Cefpodoxime (Vantin®) 3rd Metronidazole gel 0.75%
Ceftibuten (Cedax®) 3rd (Metrogel-vaginal,
Ceftriaxone (Rocephin®) 3rd Vandazole) - one full
Ceph generations (IV&PO) applicator (5g) intravaginally
once daily for 5 days
CLINDAMYCIN (CLEOCIN®)
(CDC,PI)
FOSFOMYCIN (MONUROL®)
Metronidazole gel 1.3%
LEFAMULIN (XENLETA®) (Nuvessa) - one applicator
OXAZOLIDINONES (5g) intravaginally one time
MACROLIDES (PI)
Metronidazole extended-
NITAZOXANIDE (ALINIA®)
release - 750 mg once daily
NITROFURANTOIN (MACROBID®)
for 7 days (PI)
NITROIMIDAZOLES Bite, animal - Metronidazole -
PENICILLINS 250 - 500 mg three times a day
+
QUINOLONES
Cefuroxime - 500 mg twice a
RIFAMYCINS day; OR
SULFONAMIDES Levofloxacin - 750 mg once
TETRACYCLINES daily; OR
Sulfamethoxazole-
OPHTHALMIC ANTIBIOTIC TABLE
trimethoprim - 800/160 twice a
OTIC ANTIBIOTIC TABLE day (IDSA)
Bite, human - Metronidazole -
250 - 500 mg three times a day
+

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Levofloxacin - 750 mg once

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daily; OR LOGIN
Ciprofloxacin - 500 mg - 750
ANTIBIOTIC CHART
mg twice a day (IDSA)
TOP Clostridium difficile - 500 mg
three times a day for 10 days
ACRONYMS
(IDSA)
CEPHALOSPORINS
Diverticulitis - Metronidazole -
Cefadroxil (Duricef®) 1st 500 mg three to four times a
Cephalexin (Keflex®) 1st day +
Cefaclor (Ceclor®) 2nd Ciprofloxacin - 500 mg twice a
Cefprozil (Cefzil®) 2nd day; OR
Cefuroxime (Ceftin®) 2nd Levofloxacin - 750 mg once
Cefdinir (Omnicef®) 3rd daily; OR
Cefditoren (Spectracef®) 3rd Sulfamethoxazole-
Cefixime (Suprax®) 3rd trimethoprim - 800/160 twice a
Cefpodoxime (Vantin®) 3rd day
Ceftibuten (Cedax®) 3rd DURATION: 7 - 14 days
Ceftriaxone (Rocephin®) 3rd Entamoeba histolytica - 750 mg
Ceph generations (IV&PO) three times a day for 5 - 10
days (IDSA/CTE)
CLINDAMYCIN (CLEOCIN®)
Giardia - 250 mg - 750 mg
FOSFOMYCIN (MONUROL®)
three times a day for 7 - 10
LEFAMULIN (XENLETA®) days (IDSA); OR 500 mg twice
OXAZOLIDINONES a day for 5 - 7 days (CTE)
MACROLIDES H. pylori treatment regimens
Trichomoniasis
NITAZOXANIDE (ALINIA®)
Women: 500 mg twice daily
NITROFURANTOIN (MACROBID®)
for 7 days (CDC)
NITROIMIDAZOLES Men: 2000 mg single dose
PENICILLINS (CDC)

QUINOLONES
Other
RIFAMYCINS
SULFONAMIDES May take standard-release
without regard to food.
TETRACYCLINES
Extended-release should be
OPHTHALMIC ANTIBIOTIC TABLE taken one hour before or 2
OTIC ANTIBIOTIC TABLE hours after meals.
Potential for disulfiram-like
reaction if taken with alcohol.
Do not ingest alcohol during, or

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23/10/2024, 20:43 Antibiotic chart

for 3 days after stopping

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metronidazole.
Liver disease
ANTIBIOTIC CHARTMild to moderate (Child-
TOP Pugh A/B): no dose
adjustment necessary
ACRONYMS
Severe (Child-Pugh C):
CEPHALOSPORINS
reduce dose by 50%
Cefadroxil (Duricef®) 1st Kidney disease - patients with
Cephalexin (Keflex®) 1st end-stage renal disease may
Cefaclor (Ceclor®) 2nd have decreased clearance.
Cefprozil (Cefzil®) 2nd Manufacturer makes no
Cefuroxime (Ceftin®) 2nd specific recommendation.
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd
Cefpodoxime (Vantin®) 3rd
Secnidazole
Ceftibuten (Cedax®) 3rd
Solosec®
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO)
Dosage forms
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®) Oral granules
LEFAMULIN (XENLETA®) 2 grams ($$$$)

OXAZOLIDINONES
Dosing
MACROLIDES
NITAZOXANIDE (ALINIA®) Adults and pediatric patients ≥ 12
NITROFURANTOIN (MACROBID®) years old
Bacterial vaginosis - 2 grams
NITROIMIDAZOLES
one time (PI)
PENICILLINS Trichomoniasis - 2 grams one
QUINOLONES time (PI)

RIFAMYCINS
Other
SULFONAMIDES
TETRACYCLINES May take without regard to food
Granules are sprinkled on
OPHTHALMIC ANTIBIOTIC TABLE
applesauce, yogurt, or pudding.
OTIC ANTIBIOTIC TABLE
Mixture should be consumed
within 30 minutes without
chewing.
Granules do not dissolve and
are not meant to be dissolved

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23/10/2024, 20:43 Antibiotic chart

in liquid
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Avoid consumption alcoholic
beverages and preparations
ANTIBIOTIC CHART
containing ethanol or propylene
TOP glycol during treatment and for
at least 2 days after completing
ACRONYMS
therapy
CEPHALOSPORINS
Liver disease - manufacturer
Cefadroxil (Duricef®) 1st makes no specific
Cephalexin (Keflex®) 1st recommendation
Cefaclor (Ceclor®) 2nd Kidney disease - manufacturer
Cefprozil (Cefzil®) 2nd makes no specific
Cefuroxime (Ceftin®) 2nd recommendation
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd
Cefpodoxime (Vantin®) 3rd
Tinidazole
Ceftibuten (Cedax®) 3rd
Tindamax®
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO)
Dosage forms
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®) Tablet
LEFAMULIN (XENLETA®) 250 mg ($)
500 mg ($)
OXAZOLIDINONES
MACROLIDES
Dosing
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®) Pediatric (3 years and older)
Entamoeba histolytica - 50
NITROIMIDAZOLES
mg/kg/day (max 2000 mg/day)
PENICILLINS given once daily for 3 days (PI)
QUINOLONES Giardia - 50 mg/kg (max 2000
mg) given as a one time dose
RIFAMYCINS
(PI)
SULFONAMIDES
TETRACYCLINES Adults
OPHTHALMIC ANTIBIOTIC TABLE Bacterial vaginosis
2000 mg once daily for 2
OTIC ANTIBIOTIC TABLE
days (CDC)
1000 mg once daily for 5
days (CDC)
Entamoeba histolytica - 2000
mg once daily for 3 days (PI)
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23/10/2024, 20:43 Antibiotic chart

Giardia - 2000 mg given as a

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dose (CTE/PI)
H. pylori treatment regimens
ANTIBIOTIC CHART
Trichomoniasis - 2000 mg
TOP single dose (CDC)

ACRONYMS
Other
CEPHALOSPORINS
Cefadroxil (Duricef®) 1st Take with food to minimize
Cephalexin (Keflex®) 1st stomach upset
Cefaclor (Ceclor®) 2nd Tinidazole is a CYP3A4
Cefprozil (Cefzil®) 2nd sensitive substrate
Cefuroxime (Ceftin®) 2nd Potential for disulfiram-like
Cefdinir (Omnicef®) 3rd reaction if taken with alcohol.
Cefditoren (Spectracef®) 3rd Do not ingest alcohol during, or
Cefixime (Suprax®) 3rd for 3 days after stopping
Cefpodoxime (Vantin®) 3rd tinidazole.
Ceftibuten (Cedax®) 3rd Liver disease - use caution.
Manufacturer makes no
Ceftriaxone (Rocephin®) 3rd
specific recommendation.
Ceph generations (IV&PO)
Kidney disease - no dose
CLINDAMYCIN (CLEOCIN®)
adjustment necessary
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®)
OXAZOLIDINONES
MACROLIDES Amoxicillin
NITAZOXANIDE (ALINIA®) Amoxil®
NITROFURANTOIN (MACROBID®)
NITROIMIDAZOLES Dosage forms

PENICILLINS Capsule
QUINOLONES 250 mg ($)
500 mg ($)
RIFAMYCINS
SULFONAMIDES Tablet
TETRACYCLINES 500 mg ($)
OPHTHALMIC ANTIBIOTIC TABLE 875 mg ($)

OTIC ANTIBIOTIC TABLE

Tablet, chewable
125 mg ($)
250 mg ($)

Suspension
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23/10/2024, 20:43 Antibiotic chart

125 mg/5 ml ($)

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200 mg/5 ml ($) LOGIN
250 mg/5 ml ($)
ANTIBIOTIC CHART
400 mg/5 ml ($)
TOP
ACRONYMS Dosing

CEPHALOSPORINS
Pediatric
Cefadroxil (Duricef®) 1st Endocarditis prophylaxis - 50
Cephalexin (Keflex®) 1st mg/kg (max 2000 mg) 30 - 60
Cefaclor (Ceclor®) 2nd minutes before procedure
Cefprozil (Cefzil®) 2nd (AHA)
Cefuroxime (Ceftin®) 2nd H. pylori - Amoxicillin - 50
Cefdinir (Omnicef®) 3rd mg/kg/day (max 2000 mg/day)
Cefditoren (Spectracef®) 3rd given in 2 divided doses +
Cefixime (Suprax®) 3rd Proton Pump Inhibitor (PPI) +
Cefpodoxime (Vantin®) 3rd Clarithromycin - 20 mg/kg/day
Ceftibuten (Cedax®) 3rd (max 1000 mg/day) given in 2
Ceftriaxone (Rocephin®) 3rd divided doses; OR
Ceph generations (IV&PO) Metronidazole - 20 mg/kg/day
(max 1000 mg/day) given in 2
CLINDAMYCIN (CLEOCIN®)
divided doses (CTE)
FOSFOMYCIN (MONUROL®)
DURATION: 10 - 14 days
LEFAMULIN (XENLETA®) H. pylori, sequential therapy -
OXAZOLIDINONES see H. pylori treatment
MACROLIDES Otitis media - 80 - 90
mg/kg/day given in 2 divided
NITAZOXANIDE (ALINIA®)
doses for 5 - 10 days (AAP)
NITROFURANTOIN (MACROBID®)
Pneumonia, community-
NITROIMIDAZOLES acquired - 90 mg/kg/day (max
PENICILLINS 4000 mg/day) given in 2
divided doses for 7 - 10 days
QUINOLONES
(IDSA)
RIFAMYCINS Sinusitis
SULFONAMIDES Standard therapy - 45
TETRACYCLINES mg/kg/day given in 2 divided
doses for a minimum of 10
OPHTHALMIC ANTIBIOTIC TABLE
days (AAP)
OTIC ANTIBIOTIC TABLE High-dose therapy - 80 to 90
mg/kg/day (max 4000
mg/day) given in 2 divided
doses for a minimum of 10
days (AAP)

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23/10/2024, 20:43 Antibiotic chart

Strep throat - 50 mg/kg/day

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mg/day) given once
daily or in 2 divided doses for
ANTIBIOTIC CHART
10 days (IDSA)
TOP
Adults
ACRONYMS
Endocarditis prophylaxis - 2000
CEPHALOSPORINS
mg 30 - 60 minutes before
Cefadroxil (Duricef®) 1st procedure (AHA)
Cephalexin (Keflex®) 1st H. pylori treatment regimens
Cefaclor (Ceclor®) 2nd Pneumonia, community-
Cefprozil (Cefzil®) 2nd acquired - 1000 mg three times
Cefuroxime (Ceftin®) 2nd a day for 5 - 14 days (IDSA)
Cefdinir (Omnicef®) 3rd Pulpitis (toothache) - 500 mg
Cefditoren (Spectracef®) 3rd three times a day for 3 - 7 days
Cefixime (Suprax®) 3rd (ADA)
Cefpodoxime (Vantin®) 3rd Strep throat - 1000 mg once
Ceftibuten (Cedax®) 3rd daily or 500 mg twice a day for
Ceftriaxone (Rocephin®) 3rd 10 days (IDSA)
Ceph generations (IV&PO) Syphilis (primary, secondary,
early latent, latent) - Amoxicillin
CLINDAMYCIN (CLEOCIN®)
1000 mg three times a day +
FOSFOMYCIN (MONUROL®)
probenecid 250 mg three times
LEFAMULIN (XENLETA®) a day for 14 - 16 days [Based
OXAZOLIDINONES on PMID 25829004]
MACROLIDES
Other
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®) May take without regard to food
NITROIMIDAZOLES Kidney disease
PENICILLINS CrCl 10 - 30 ml/min: 250 -
500 mg every 12 hours
QUINOLONES
CrCl < 10 ml/min: 250 - 500
RIFAMYCINS mg every 24 hours
SULFONAMIDES
TETRACYCLINES
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE Amoxicillin-Clavulanate
potassium
Augmentin®

Dosage forms

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JOIN Tablet (amoxil : clav)

Straight Healthcare NEWSLETTER 250 mg SUBSCRIBE LOGIN
: 125 mg ($)
500 mg : 125 mg ($)
ANTIBIOTIC CHART
875 mg : 125 mg ($)
TOP
ACRONYMS Tablet, chewable (amoxil : clav)
CEPHALOSPORINS 200 mg : 28.5 mg ($)
400 mg : 57 mg ($)
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st
Tablet, extended-release (Augmentin
Cefaclor (Ceclor®) 2nd
XR®)
Cefprozil (Cefzil®) 2nd
1000 mg : 62.5 mg ($$-$$$)
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd
Suspension (amoxil:clav)
Cefditoren (Spectracef®) 3rd
4:1 ratio
Cefixime (Suprax®) 3rd
125 mg : 31.25 mg/5 ml ($$$$)
Cefpodoxime (Vantin®) 3rd
250 mg : 62.5 mg/5 ml ($)
Ceftibuten (Cedax®) 3rd
7:1 ratio
Ceftriaxone (Rocephin®) 3rd
200 mg : 28.5 mg/5 ml ($)
Ceph generations (IV&PO)
400 mg : 57 mg/5 ml ($)
CLINDAMYCIN (CLEOCIN®) 14:1 ratio (Augmentin ES®)
FOSFOMYCIN (MONUROL®) 600 mg : 42.9 mg/5 ml ($)
LEFAMULIN (XENLETA®)
OXAZOLIDINONES Dosing

MACROLIDES
Pediatric
NITAZOXANIDE (ALINIA®) Impetigo - 25 mg/kg/day (max
NITROFURANTOIN (MACROBID®) 1750 mg/day) of the amoxicillin
NITROIMIDAZOLES component given in 2 divided
doses for 7 days (IDSA)
PENICILLINS
Otitis media - 90 mg/kg/day of
QUINOLONES amoxicillin, with 6.4 mg/kg/day
RIFAMYCINS of clavulanate [amoxicillin to
clavulanate ratio, 14:1] (max
SULFONAMIDES
4000 mg/day) in 2 divided
TETRACYCLINES doses for 5 - 10 days (AAP)
OPHTHALMIC ANTIBIOTIC TABLE Pneumonia, community-
OTIC ANTIBIOTIC TABLE acquired - 90 mg/kg/day (max
4000 mg/day) given in 2
divided doses for 7 - 10 days
(IDSA)
Sinusitis - 80 - 90 mg/kg/day of
the amoxicillin component with
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23/10/2024, 20:43 Antibiotic chart

6.4 mg/kg/day of clavulanate

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[amoxicillin LOGIN
to clavulanate ratio,
14:1] in 2 divided doses (max
ANTIBIOTIC CHART
4000 mg/day) for a minimum of
TOP 10 days (AAP)
Urinary tract infection - 20 - 40
ACRONYMS
mg/kg/day given in 3 divided
CEPHALOSPORINS
doses for 7 - 14 days (CTE)
Cefadroxil (Duricef®) 1st Urinary tract infection,
Cephalexin (Keflex®) 1st prophylaxis - 15 mg/kg/day
Cefaclor (Ceclor®) 2nd (amoxicillin component) given
Cefprozil (Cefzil®) 2nd once daily (CTE)
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd Adults
Cefditoren (Spectracef®) 3rd Bite, animal - 875/125 mg twice
Cefixime (Suprax®) 3rd a day (IDSA)
Cefpodoxime (Vantin®) 3rd Bite, human - 875/125 mg twice
Ceftibuten (Cedax®) 3rd a day (IDSA)
Ceftriaxone (Rocephin®) 3rd Diabetic foot ulcer (mild, non-
Ceph generations (IV&PO) MRSA) - 875/125 mg twice a
day for 7 - 14 days (IDSA)
CLINDAMYCIN (CLEOCIN®)
Diverticulitis - 875/125 mg twice
FOSFOMYCIN (MONUROL®)
a day for 7 - 14 days (CTE)
LEFAMULIN (XENLETA®) Impetigo - 875/125 mg twice a
OXAZOLIDINONES day for 7 days (IDSA)
MACROLIDES Pneumonia, community-
acquired - Amoxicillin-
NITAZOXANIDE (ALINIA®)
clavulanate 500/125 mg three
NITROFURANTOIN (MACROBID®)
times daily OR 875/125 mg
NITROIMIDAZOLES twice daily OR 2000/125 mg
PENICILLINS twice daily + macrolide or
doxycycline for 5 - 14 days
QUINOLONES
(IDSA)
RIFAMYCINS Pulpitis (toothache) - 500/125
SULFONAMIDES mg three times a day for 7 days
TETRACYCLINES (ADA)
Sinusitis
OPHTHALMIC ANTIBIOTIC TABLE
Standard therapy - 875/125
OTIC ANTIBIOTIC TABLE mg twice a day for 5 - 7 days
(IDSA)
High-dose therapy - 2000
mg twice a day for 5 - 7 days
(IDSA)

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Urinary tract infection - 875/125

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mg twice a day for 3 -LOGIN
7 days
(IDSA)
ANTIBIOTIC CHART
TOP Other

ACRONYMS
May take without regard to
CEPHALOSPORINS meals, although taking with
Cefadroxil (Duricef®) 1st food may help reduce
Cephalexin (Keflex®) 1st gastrointestinal upset
Cefaclor (Ceclor®) 2nd Amoxicillin-clavulanate
Cefprozil (Cefzil®) 2nd preparations with a 14:1 ratio of
Cefuroxime (Ceftin®) 2nd amoxicillin-clavulanate may be
Cefdinir (Omnicef®) 3rd less likely to cause diarrhea
Cefditoren (Spectracef®) 3rd than preparations with a lower
Cefixime (Suprax®) 3rd ratio
Cefpodoxime (Vantin®) 3rd Kidney disease
Standard tablet and
Ceftibuten (Cedax®) 3rd
suspension
Ceftriaxone (Rocephin®) 3rd
CrCl < 30 ml/min: do not
Ceph generations (IV&PO)
give 875 mg dose
CLINDAMYCIN (CLEOCIN®)
CrCl 10 - 30 ml/min: 250 -
FOSFOMYCIN (MONUROL®) 500 mg every 12 hours
LEFAMULIN (XENLETA®) CrCl < 10 ml/min: 250 - 500
OXAZOLIDINONES mg every 24 hours

MACROLIDES
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®)
NITROIMIDAZOLES
Dicloxacillin

PENICILLINS Dosage forms

QUINOLONES
Capsule
RIFAMYCINS
250 mg
SULFONAMIDES 500 mg ($)
TETRACYCLINES
OPHTHALMIC ANTIBIOTIC TABLE Dosing

OTIC ANTIBIOTIC TABLE Pediatric

Cellulitis (non-MRSA) - 25 - 50
mg/kg/day (max 2000 mg/day)
given in 4 divided doses for 5 -
10 days (IDSA)

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23/10/2024, 20:43 Antibiotic chart

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(non-MRSA) - 500 mg
four times a day for 5 - 10 days
ANTIBIOTIC CHART
(IDSA)
TOP Diabetic foot ulcer (mild, non-
ACRONYMS MRSA) - 500 mg four times a
CEPHALOSPORINS day for 7 - 14 days (IDSA)
Impetigo - 250 mg four times a
Cefadroxil (Duricef®) 1st
day for 7 days (IDSA)
Cephalexin (Keflex®) 1st
Cefaclor (Ceclor®) 2nd
Other
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd Should be taken on an empty
Cefdinir (Omnicef®) 3rd stomach at least 1 hour before
Cefditoren (Spectracef®) 3rd and 2 hours after a meal
Cefixime (Suprax®) 3rd Kidney disease - dose
Cefpodoxime (Vantin®) 3rd reduction recommended.
Ceftibuten (Cedax®) 3rd Manufacturer makes no
Ceftriaxone (Rocephin®) 3rd specific recommendation.
Ceph generations (IV&PO)
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Penicillin G benzathine
OXAZOLIDINONES Bicillin L-A®
MACROLIDES
Dosage forms
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®) Disposable syringe
NITROIMIDAZOLES 1 ml - 600,000 units ($$)
2 ml - 1,200,000 units ($$$$)
PENICILLINS
4 ml - 2,400,000 units ($$$$)
QUINOLONES
RIFAMYCINS Dosing
SULFONAMIDES
Pediatric
TETRACYCLINES Rheumatic fever prevention
OPHTHALMIC ANTIBIOTIC TABLE ≤ 27 kg: 600,000 units IM
OTIC ANTIBIOTIC TABLE every 4 weeks (AHA/AAP)
> 27 kg: 1,200,000 units IM
every 4 weeks (AHA/AAP)
Strep throat
< 27 kg: 600,000 units IM
single dose (IDSA)
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23/10/2024, 20:43 Antibiotic chart

≥ 27 kg: 1,200,000 units IM

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dose (IDSA)LOGIN
Impetigo
ANTIBIOTIC CHART≤ 6 kg: 225 mg (300,000
TOP units) IM given as a one time
dose
ACRONYMS
6.1 - 10 kg: 337.5 mg
CEPHALOSPORINS
(450,000 units) IM given as a
Cefadroxil (Duricef®) 1st one time dose
Cephalexin (Keflex®) 1st 10.1 - 15 kg: 450 mg
Cefaclor (Ceclor®) 2nd (600,000 units) IM given as a
Cefprozil (Cefzil®) 2nd one time dose
Cefuroxime (Ceftin®) 2nd 15.1 - 20 kg: 675 mg
Cefdinir (Omnicef®) 3rd (900,000 units) IM given as a
Cefditoren (Spectracef®) 3rd one time dose
Cefixime (Suprax®) 3rd > 20 kg: 900 mg (1,200,000
Cefpodoxime (Vantin®) 3rd units) IM given as a one time
Ceftibuten (Cedax®) 3rd dose
Ceftriaxone (Rocephin®) 3rd [Based on PMID 25172376]
Ceph generations (IV&PO)
Adults
CLINDAMYCIN (CLEOCIN®)
Rheumatic fever prevention -
FOSFOMYCIN (MONUROL®)
1,200,000 units IM every 4
LEFAMULIN (XENLETA®) weeks (AHA)
OXAZOLIDINONES Strep throat - 1,200,000 units
MACROLIDES IM single dose
Syphilis
NITAZOXANIDE (ALINIA®)
Primary and secondary - 2.4
NITROFURANTOIN (MACROBID®)
million units IM single dose
NITROIMIDAZOLES (CDC)
PENICILLINS Early latent - 2.4 million units
IM single dose (CDC)
QUINOLONES
Latent - 2.4 million units IM
RIFAMYCINS once a week for a total of 3
SULFONAMIDES doses (CDC)
TETRACYCLINES Tertiary - 2.4 million units IM
once a week for a total of 3
OPHTHALMIC ANTIBIOTIC TABLE
doses (CDC)
OTIC ANTIBIOTIC TABLE

Other

For intramuscular use only

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Kidney disease - clearance is

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decreased. LOGIN
Manufacturer
makes no specific
ANTIBIOTIC CHART
recommendation.
TOP Milligram-unit conversion
ACRONYMS 225 mg = 300,000 units
337.5 mg = 450,000 units
CEPHALOSPORINS
450 mg = 600,000 units
Cefadroxil (Duricef®) 1st
675 mg = 900,000 units
Cephalexin (Keflex®) 1st
900 mg = 1,200,000 units
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd Penicillin
Cefixime (Suprax®) 3rd Pen VK®
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd Dosage forms
Ceftriaxone (Rocephin®) 3rd
Tablet
Ceph generations (IV&PO)
250 mg ($)
CLINDAMYCIN (CLEOCIN®) 500 mg ($)
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Solution
OXAZOLIDINONES 125 mg/5 ml ($)
250 mg/5 ml ($)
MACROLIDES
NITAZOXANIDE (ALINIA®)
Dosing
NITROFURANTOIN (MACROBID®)
NITROIMIDAZOLES Pediatric
Rheumatic fever prevention -
PENICILLINS
250 mg twice daily (AAP/AHA)
QUINOLONES Strep throat - 250 mg two to
RIFAMYCINS three times a day for 10 days
SULFONAMIDES (IDSA)

TETRACYCLINES
Adults
OPHTHALMIC ANTIBIOTIC TABLE Cellulitis (Streptococcal
OTIC ANTIBIOTIC TABLE infections) - 250 - 500 mg four
times a day for 5 - 10 days
(IDSA)
Pulpitis (toothache) - 500 mg
four times a day for 3 - 7 days

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23/10/2024, 20:43 Antibiotic chart

(ADA)
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Rheumatic LOGIN -
fever prevention
250 mg twice daily (AHA)
ANTIBIOTIC CHART
Strep throat - 250 mg four
TOP times a day or 500 mg twice a
day for 10 days (IDSA)
ACRONYMS
CEPHALOSPORINS
Other
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st May take without regard to
Cefaclor (Ceclor®) 2nd meals
Cefprozil (Cefzil®) 2nd Kidney disease - drug
Cefuroxime (Ceftin®) 2nd clearance is decreased.
Cefdinir (Omnicef®) 3rd Manufacturer makes no
Cefditoren (Spectracef®) 3rd specific dosage
Cefixime (Suprax®) 3rd recommendation.
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO) Pivmecillinam
CLINDAMYCIN (CLEOCIN®) Pivya®
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Dosage forms
OXAZOLIDINONES
Tablet
MACROLIDES 185 mg ($$$$)
NITAZOXANIDE (ALINIA®) Comes in pack of 9 tablets
NITROFURANTOIN (MACROBID®)
Dosing
NITROIMIDAZOLES
PENICILLINS Adults (female)
QUINOLONES Urinary tract infection - 185 mg
three times a day for 3 - 7 days
RIFAMYCINS
(PI)
SULFONAMIDES
TETRACYCLINES Other
OPHTHALMIC ANTIBIOTIC TABLE
May take without regard to
OTIC ANTIBIOTIC TABLE meals
Pivya contains pivalate, an acid
that improves absorption but
also depletes carnitine, a
compound involved in muscle

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23/10/2024, 20:43 Antibiotic chart

fatty acid metabolism. It should

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not be given LOGIN
to patients with
carnitine deficiency or those
ANTIBIOTIC CHART
receiving other carnitine-
TOP depleting drugs, including
valproic acid, valproate,
ACRONYMS
carbamazepine, and phenytoin.
CEPHALOSPORINS
Kidney disease - no dose
Cefadroxil (Duricef®) 1st adjustment necessary
Cephalexin (Keflex®) 1st
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd Ciprofloxacin
Cefditoren (Spectracef®) 3rd Cipro®
Cefixime (Suprax®) 3rd
Cefpodoxime (Vantin®) 3rd Dosage forms

Ceftibuten (Cedax®) 3rd Tablet

Ceftriaxone (Rocephin®) 3rd 100 mg (?)
Ceph generations (IV&PO) 250 mg ($)
CLINDAMYCIN (CLEOCIN®) 500 mg ($)
FOSFOMYCIN (MONUROL®) 750 mg ($)
LEFAMULIN (XENLETA®)
Tablet, extended-release (Cipro XR®)
OXAZOLIDINONES
500 mg ($-$$)
MACROLIDES 1000 mg ($-$$)
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®) Suspension
NITROIMIDAZOLES 250 mg/5 ml ($-$$)
500 mg/5 ml ($-$$)
PENICILLINS
QUINOLONES Ophthalmic
RIFAMYCINS See conjunctivitis

SULFONAMIDES
Otic
TETRACYCLINES
See Otitis externa
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE Dosing

Pediatric (≥ 1 year old)

Urinary tract infection - 10 - 20
mg/kg/dose (maximum 750

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23/10/2024, 20:43 Antibiotic chart

mg/dose) every 12 hours for 7 -

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(PI) LOGIN

ANTIBIOTIC CHART
Adults
TOP Bite, human - Ciprofloxacin -
500 - 750 mg twice a day +
ACRONYMS
metronidazole 250 - 500 mg
CEPHALOSPORINS
three times a day (IDSA)
Cefadroxil (Duricef®) 1st Diabetic foot ulcer (moderate) -
Cephalexin (Keflex®) 1st Ciprofloxacin 500 mg twice a
Cefaclor (Ceclor®) 2nd day + clindamycin 300 - 450
Cefprozil (Cefzil®) 2nd mg four times a day for 7 - 14
Cefuroxime (Ceftin®) 2nd days (IDSA)
Cefdinir (Omnicef®) 3rd Diarrhea, bacterial - 500 mg
Cefditoren (Spectracef®) 3rd twice a day for 5 - 7 days (PI)
Cefixime (Suprax®) 3rd Diverticulitis - Ciprofloxacin 500
Cefpodoxime (Vantin®) 3rd mg twice a day + metronidazole
Ceftibuten (Cedax®) 3rd 500 mg three to four times a
Ceftriaxone (Rocephin®) 3rd day for 7 - 14 days (CTE)
Ceph generations (IV&PO) E Coli, enterotoxigenic - 500
mg twice a day or 750 mg once
CLINDAMYCIN (CLEOCIN®)
daily for 1 - 3 days (CTE/IDSA)
FOSFOMYCIN (MONUROL®)
Prostatitis, acute - 500 mg
LEFAMULIN (XENLETA®) twice a day for 2 - 4 weeks
OXAZOLIDINONES (CTE)
MACROLIDES Prostatitis, chronic - 500 mg
twice a day for 4 - 6 weeks
NITAZOXANIDE (ALINIA®)
(CTE, PI)
NITROFURANTOIN (MACROBID®)
Pyelonephritis
NITROIMIDAZOLES Standard-release - 500 mg
PENICILLINS twice a day for 7 days
(IDSA)
QUINOLONES
Extended-release - 1000 mg
RIFAMYCINS once daily for 7 days (IDSA)
SULFONAMIDES NOTE: If community
TETRACYCLINES resistance to
fluoroquinolones is > 10%,
OPHTHALMIC ANTIBIOTIC TABLE
then also give Ceftriaxone
OTIC ANTIBIOTIC TABLE 1000 mg IM one time dose
(IDSA)
Salmonella, nontyphoidal - 500
mg twice a day for 5 - 10 days
(CTE/IDSA)

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23/10/2024, 20:43 Antibiotic chart

Shigella - 750 mg once daily or

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twice a day for 3 days
(CTE/IDSA)
ANTIBIOTIC CHART
Sinusitis - 500 mg twice a day
TOP for 10 days (PI)
Urinary tract infection
ACRONYMS
Standard-release - 250 mg
CEPHALOSPORINS
twice a day for 3 days (IDSA,
Cefadroxil (Duricef®) 1st PI)
Cephalexin (Keflex®) 1st Extended-release - 500 mg
Cefaclor (Ceclor®) 2nd once daily for 3 days (IDSA,
Cefprozil (Cefzil®) 2nd PI)
Cefuroxime (Ceftin®) 2nd Vibrio vulnificus - 750 mg once
Cefdinir (Omnicef®) 3rd daily for 3 days (CTE)
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd Other
Cefpodoxime (Vantin®) 3rd
May take without regard to food
Ceftibuten (Cedax®) 3rd
Do not take with tizanidine
Ceftriaxone (Rocephin®) 3rd
(Zanaflex®)
Ceph generations (IV&PO)
Take 2 hours before or 6 hours
CLINDAMYCIN (CLEOCIN®)
after magnesium- or aluminum-
FOSFOMYCIN (MONUROL®) containing antacids
LEFAMULIN (XENLETA®) Ciprofloxacin is a Strong
OXAZOLIDINONES CYP1A2 inhibitor
May cause photosensitivity.
MACROLIDES
Limit sun exposure and use
NITAZOXANIDE (ALINIA®)
sunscreen.
NITROFURANTOIN (MACROBID®) Liver disease - in studies
NITROIMIDAZOLES involving patients with chronic
PENICILLINS cirrhosis, no significant
changes in ciprofloxacin
QUINOLONES
pharmacokinetics were
RIFAMYCINS observed. The effects of acute
SULFONAMIDES hepatic insufficiency on
ciprofloxacin are unknown.
TETRACYCLINES
Kidney disease
OPHTHALMIC ANTIBIOTIC TABLE Standard-release
OTIC ANTIBIOTIC TABLE CrCl > 50 ml/min: no dose
adjustment necessary
CrCl 30 - 50 ml/min: 250 -
500 mg every 12 hours

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23/10/2024, 20:43 Antibiotic chart

CrCl 5 - 29 ml/min: 250 -

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mg every 18 hours
Extended-release
ANTIBIOTIC CHARTCrCl ≤ 30 ml/min: 500 mg
TOP once daily

ACRONYMS
CEPHALOSPORINS
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st Delafloxacin
Cefaclor (Ceclor®) 2nd Baxdela™
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd Dosage forms
Cefdinir (Omnicef®) 3rd
Tablet
Cefditoren (Spectracef®) 3rd
450 mg ($$$$)
Cefixime (Suprax®) 3rd
Cefpodoxime (Vantin®) 3rd
Dosing
Ceftibuten (Cedax®) 3rd
Ceftriaxone (Rocephin®) 3rd Adults
Ceph generations (IV&PO) Pneumonia, community-
CLINDAMYCIN (CLEOCIN®) acquired - 450 mg every 12
FOSFOMYCIN (MONUROL®) hours for 5 - 10 days (PI)
Skin and skin structure
LEFAMULIN (XENLETA®)
infections (including MRSA) -
OXAZOLIDINONES
450 mg every 12 hours for 5 -
MACROLIDES 14 days (PI)
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®) Other

NITROIMIDAZOLES
May take without regard to food
PENICILLINS Take 2 hours before or 6 hours
QUINOLONES after chelating agents (e.g.
magnesium or aluminum
RIFAMYCINS
antacids, sucralfate,
SULFONAMIDES multivitamins, iron)
TETRACYCLINES Liver disease - no dosage
adjustment necessary
OPHTHALMIC ANTIBIOTIC TABLE
Kidney disease
OTIC ANTIBIOTIC TABLE
CrCl ≥ 15 ml/min: no dose
adjustment necessary for
tablets

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23/10/2024, 20:43 Antibiotic chart

CrCl < 15 ml/min: not

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recommended

ANTIBIOTIC CHART
TOP
ACRONYMS Gemifloxacin
CEPHALOSPORINS Factive®
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st Dosage forms
Cefaclor (Ceclor®) 2nd
Tablet
Cefprozil (Cefzil®) 2nd
320 mg ($$$$)
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd
Dosing
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd Adults
Cefpodoxime (Vantin®) 3rd Gonorrhea (cervical, urethral,
Ceftibuten (Cedax®) 3rd rectal, pharyngeal)
Ceftriaxone (Rocephin®) 3rd Gemifloxacin 320 mg single
Ceph generations (IV&PO) dose + azithromycin 2000
CLINDAMYCIN (CLEOCIN®) mg single dose [Based on
FOSFOMYCIN (MONUROL®) PMID 25031289]
Pneumonia, community-
LEFAMULIN (XENLETA®)
acquired - 320 mg once daily
OXAZOLIDINONES
for 5 - 7 days (IDSA, PI)
MACROLIDES
NITAZOXANIDE (ALINIA®) Other
NITROFURANTOIN (MACROBID®)
May take without regard to food
NITROIMIDAZOLES
Antacids, sucralfate, metal
PENICILLINS cations (e.g. iron), and
QUINOLONES multivitamins may reduce
gemifloxacin absorption.
RIFAMYCINS
Gemifloxacin should be taken 3
SULFONAMIDES hours before or 2 hours after
TETRACYCLINES these medications.
Liver disease - no dose
OPHTHALMIC ANTIBIOTIC TABLE
adjustment necessary
OTIC ANTIBIOTIC TABLE
Kidney disease
CrCl ≤ 40 ml/min: 160 mg
every 24 hours

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23/10/2024, 20:43 Antibiotic chart

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Levofloxacin
ANTIBIOTIC CHART
Levaquin®
TOP
ACRONYMS Dosage forms

CEPHALOSPORINS Tablet
Cefadroxil (Duricef®) 1st 250 mg ($)
Cephalexin (Keflex®) 1st 500 mg ($)
Cefaclor (Ceclor®) 2nd 750 mg ($)
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd Solution
Cefdinir (Omnicef®) 3rd 25 mg/ml ($$)
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd Ophthalmic
Cefpodoxime (Vantin®) 3rd See conjunctivitis
Ceftibuten (Cedax®) 3rd
Ceftriaxone (Rocephin®) 3rd Dosing
Ceph generations (IV&PO)
CLINDAMYCIN (CLEOCIN®) Pediatric
Pneumonia, community-
FOSFOMYCIN (MONUROL®)
acquired
LEFAMULIN (XENLETA®)
6 months - 5 years old - 16 -
OXAZOLIDINONES 20 mg/kg/day given in 2
MACROLIDES divided doses for 7 - 10 days
(IDSA)
NITAZOXANIDE (ALINIA®)
5 - 16 years old - 8 - 10
NITROFURANTOIN (MACROBID®)
mg/kg/day (max 750
NITROIMIDAZOLES mg/day) given once daily for
PENICILLINS 7 - 10 days (IDSA)
QUINOLONES Sinusitis - 16 mg/kg/day (max
500 mg/day) given in 2 divided
RIFAMYCINS
doses for a minimum of 10
SULFONAMIDES days (AAP)
TETRACYCLINES
Adults
OPHTHALMIC ANTIBIOTIC TABLE
Bite, animal - Levofloxacin 750
OTIC ANTIBIOTIC TABLE
mg once daily +
clindamycin 300 mg three
times a day; OR
metronidazole 250 - 500 mg
three times a day (IDSA)

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23/10/2024, 20:43 Antibiotic chart

Bite, human - Levofloxacin 750

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daily + metronidazole
250 - 500 mg three times a day
ANTIBIOTIC CHART
(IDSA)
TOP Chlamydia - 500 mg once daily
for 7 days (CDC)
ACRONYMS
Diabetic foot ulcer (mild, non-
CEPHALOSPORINS
MRSA) - 750 mg once daily for
Cefadroxil (Duricef®) 1st 7 - 14 days (IDSA)
Cephalexin (Keflex®) 1st Diabetic foot ulcer (moderate) -
Cefaclor (Ceclor®) 2nd Levofloxacin 750 mg once daily
Cefprozil (Cefzil®) 2nd + clindamycin 300 - 450 mg
Cefuroxime (Ceftin®) 2nd four times a day for 7 - 14 days
Cefdinir (Omnicef®) 3rd (IDSA)
Cefditoren (Spectracef®) 3rd Diverticulitis - Levofloxacin 750
Cefixime (Suprax®) 3rd mg once daily + metronidazole
Cefpodoxime (Vantin®) 3rd 500 mg three to four times a
Ceftibuten (Cedax®) 3rd day for 7 - 14 days (CTE)
Ceftriaxone (Rocephin®) 3rd Epididymitis
Ceph generations (IV&PO) Likely caused by enteric or
urinary tract pathogen -
CLINDAMYCIN (CLEOCIN®)
Levofloxacin 500 mg once
FOSFOMYCIN (MONUROL®)
daily for 10 days (CDC)
LEFAMULIN (XENLETA®) Likely caused by chlamydia,
OXAZOLIDINONES gonorrhea, and/or enteric
MACROLIDES organisms - Ceftriaxone 500
mg IM (1000 mg if ≥ 330 lbs)
NITAZOXANIDE (ALINIA®)
single dose + Levofloxacin
NITROFURANTOIN (MACROBID®)
500 mg once daily for 10
NITROIMIDAZOLES days (CDC)
PENICILLINS H. pylori treatment regimens
Pneumonia, community-
QUINOLONES
acquireda - 500 mg once daily
RIFAMYCINS for 7 - 14 days (PI)
SULFONAMIDES Pneumonia, community-
TETRACYCLINES acquiredb - 750 mg once daily
for 5 days (IDSA, PI)
OPHTHALMIC ANTIBIOTIC TABLE
Pneumonia, nosocomial - 750
OTIC ANTIBIOTIC TABLE mg once daily for 7 - 14 days
(PI)
Prostatitis, acute - 500 mg -
750 mg once daily for 2 - 4
weeks (CTE)

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23/10/2024, 20:43 Antibiotic chart

Prostatitis, chronic - 500 mg

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once daily LOGIN
for 4 - 6 weeks
(CTE, PI)
ANTIBIOTIC CHART
Pyelonephritis - 750 mg once
TOP daily for 5 days; if community
resistance to fluoroquinolones
ACRONYMS
is > 10%, then also give
CEPHALOSPORINS
Ceftriaxone 1000 mg IM one
Cefadroxil (Duricef®) 1st time dose (IDSA)
Cephalexin (Keflex®) 1st Salmonella, nontyphoidal - 500
Cefaclor (Ceclor®) 2nd mg once daily for 5 - 10 days
Cefprozil (Cefzil®) 2nd (CTE/IDSA)
Cefuroxime (Ceftin®) 2nd Sinusitis - 750 mg once daily
Cefdinir (Omnicef®) 3rd for 5 days OR 500 mg once
Cefditoren (Spectracef®) 3rd daily for 10 - 14 days (IDSA, PI)
Cefixime (Suprax®) 3rd Skin infections, complicated -
Cefpodoxime (Vantin®) 3rd 750 mg once daily for 7 - 14
Ceftibuten (Cedax®) 3rd days (PI)
Ceftriaxone (Rocephin®) 3rd Skin infections, uncomplicated -
Ceph generations (IV&PO) 500 mg once daily for 7 - 10
days (PI)
CLINDAMYCIN (CLEOCIN®)
Urinary tract infection - 250 mg
FOSFOMYCIN (MONUROL®)
once daily for 3 days (IDSA, PI)
LEFAMULIN (XENLETA®) Urinary tract infection,
OXAZOLIDINONES complicatedc - 750 mg once
MACROLIDES daily for 5 days (PI)
Urinary tract infection,
NITAZOXANIDE (ALINIA®)
complicatedd - 250 mg once
NITROFURANTOIN (MACROBID®)
daily for 10 days (PI)
NITROIMIDAZOLES aDue to methicillin-susceptible
PENICILLINS Staphylococcus aureus,
Streptococcus pneumoniae
QUINOLONES
(including multidrug-resistant
RIFAMYCINS isolates [MDRSP]), Haemophilus
SULFONAMIDES influenzae, Haemophilus
TETRACYCLINES parainfluenzae, Klebsiella
pneumoniae, Moraxella
OPHTHALMIC ANTIBIOTIC TABLE
catarrhalis, Chlamydophila
OTIC ANTIBIOTIC TABLE pneumoniae, Legionella
pneumophila, or Mycoplasma
pneumoniae
bDueto Streptococcus
pneumoniae (excluding multi-

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23/10/2024, 20:43 Antibiotic chart

drug-resistant isolates
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Haemophilus LOGIN
influenzae, Haemophilus
ANTIBIOTIC CHART
parainfluenzae, Mycoplasma
TOP pneumoniae, or Chlamydophila
pneumoniae
ACRONYMS cdue to Escherichia coli,
CEPHALOSPORINS
Klebsiella pneumoniae, Proteus
Cefadroxil (Duricef®) 1st mirabilis and pyelonephritis due
Cephalexin (Keflex®) 1st to E. coli, including cases with
Cefaclor (Ceclor®) 2nd concurrent bacteremia
Cefprozil (Cefzil®) 2nd d Enterococcus faecalis,
Cefuroxime (Ceftin®) 2nd Enterococcus cloacae,
Cefdinir (Omnicef®) 3rd Escherichia coli, Klebsiella
Cefditoren (Spectracef®) 3rd pneumoniae, Proteus mirabilis,
Cefixime (Suprax®) 3rd Pseudomonas aeruginosa; and
Cefpodoxime (Vantin®) 3rd for pyelonephritis due to E. coli
Ceftibuten (Cedax®) 3rd
Ceftriaxone (Rocephin®) 3rd Other
Ceph generations (IV&PO)
May take without regard to food
CLINDAMYCIN (CLEOCIN®)
Antacids, sucralfate, metal
FOSFOMYCIN (MONUROL®) cations (e.g. iron), and
LEFAMULIN (XENLETA®) multivitamins may reduce
OXAZOLIDINONES levofloxacin absorption. Do not
take within 2 hours of each
MACROLIDES
other.
NITAZOXANIDE (ALINIA®)
Quinolones have not been
NITROFURANTOIN (MACROBID®) considered first-line agents in
NITROIMIDAZOLES children because of the
PENICILLINS possible risk of adverse effects
on developing cartilage. In
QUINOLONES
studies, these effects appear to
RIFAMYCINS be uncommon. [1]
SULFONAMIDES May cause photosensitivity.
Limit sun exposure and use
TETRACYCLINES
sunscreen.
OPHTHALMIC ANTIBIOTIC TABLE Liver disease - no dose
OTIC ANTIBIOTIC TABLE adjustment necessary
Kidney disease

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23/10/2024, 20:43 Antibiotic chart

CrCl ≤ 49 ml/min: dose

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adjustment LOGIN
recommended;
see Levaquin® PI for more.
ANTIBIOTIC CHART
TOP
ACRONYMS
CEPHALOSPORINS Moxifloxacin
Cefadroxil (Duricef®) 1st Avelox®
Cephalexin (Keflex®) 1st
Cefaclor (Ceclor®) 2nd Dosage forms
Cefprozil (Cefzil®) 2nd
Tablet
Cefuroxime (Ceftin®) 2nd
400 mg ($)
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd
Ophthalmic
Cefixime (Suprax®) 3rd
See conjunctivitis
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd
Dosing
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO) Adults
CLINDAMYCIN (CLEOCIN®) Appendicitis, uncomplicated -
FOSFOMYCIN (MONUROL®) 400 mg once daily for 7 days
LEFAMULIN (XENLETA®) [Based on PMID 33427870]
Bite, animal - 400 mg once
OXAZOLIDINONES
daily (IDSA)
MACROLIDES Bite, human - 400 mg once
NITAZOXANIDE (ALINIA®) daily (IDSA)
NITROFURANTOIN (MACROBID®) Diabetic foot ulcer (moderate,
NITROIMIDAZOLES non-MRSA) - 400 mg once
daily for 7 - 14 days (IDSA)
PENICILLINS
Diverticulitis - 400 mg once
QUINOLONES daily for 7 - 14 days (CTE)
RIFAMYCINS Mycoplasma genitalium
(macrolide resistant or
SULFONAMIDES
unknown) - Doxycycline 100
TETRACYCLINES mg twice daily for 7 days,
OPHTHALMIC ANTIBIOTIC TABLE followed by moxifloxacin 400
OTIC ANTIBIOTIC TABLE mg once daily for 7 days (CDC)
Pneumonia, community-
acquired - 400 mg once daily
for 7 - 14 days (IDSA, PI)
Sinusitis - 400 mg once daily
for 10 days (IDSA, PI)
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23/10/2024, 20:43 Antibiotic chart

Skin infections, uncomplicated -

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once daily forLOGIN
7 days
(PI)
ANTIBIOTIC CHART
Skin infections, complicated -
TOP 400 mg once daily for 7 - 21
days (PI)
ACRONYMS
CEPHALOSPORINS
Other
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st May take without regard to food
Cefaclor (Ceclor®) 2nd Antacids, sucralfate, metal
Cefprozil (Cefzil®) 2nd cations (e.g. iron), and
Cefuroxime (Ceftin®) 2nd multivitamins may reduce
Cefdinir (Omnicef®) 3rd moxifloxacin absorption.
Cefditoren (Spectracef®) 3rd Moxifloxacin should be taken 4
Cefixime (Suprax®) 3rd hours before or 8 hours after
Cefpodoxime (Vantin®) 3rd these medications.
Ceftibuten (Cedax®) 3rd Liver disease - no dose
adjustment necessary
Ceftriaxone (Rocephin®) 3rd
Kidney disease - no dose
Ceph generations (IV&PO)
adjustment necessary
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®)
OXAZOLIDINONES
Ofloxacin
MACROLIDES
NITAZOXANIDE (ALINIA®) Dosage forms
NITROFURANTOIN (MACROBID®)
Tablet
NITROIMIDAZOLES 200 mg
PENICILLINS 300 mg
400 mg ($$)
QUINOLONES
RIFAMYCINS
Ophthalmic
SULFONAMIDES See conjunctivitis
TETRACYCLINES
OPHTHALMIC ANTIBIOTIC TABLE Otic
See otitis externa
OTIC ANTIBIOTIC TABLE

Dosing

Adults

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23/10/2024, 20:43 Antibiotic chart

Chlamydia - 300 mg twice a

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day for 7 days (CDC) LOGIN
E. coli, enterotoxigenic - 300
ANTIBIOTIC CHART
mg twice a day for 3 days
TOP (IDSA)
Epididymitis (likely caused by
ACRONYMS
urinary tract pathogens) - 300
CEPHALOSPORINS
mg twice a day for 10 days
Cefadroxil (Duricef®) 1st (CDC)
Cephalexin (Keflex®) 1st Pelvic inflammatory disease -
Cefaclor (Ceclor®) 2nd 400 mg twice a day for 10 - 14
Cefprozil (Cefzil®) 2nd days (PI)
Cefuroxime (Ceftin®) 2nd Pneumonia, community-
Cefdinir (Omnicef®) 3rd acquired - 400 mg twice a day
Cefditoren (Spectracef®) 3rd for 10 days (PI)
Cefixime (Suprax®) 3rd Prostatitis due to E. coli - 300
Cefpodoxime (Vantin®) 3rd mg twice a day for 6 weeks (PI)
Ceftibuten (Cedax®) 3rd Salmonella, nontyphoidal - 300
Ceftriaxone (Rocephin®) 3rd mg twice a day for 5 -7 days
Ceph generations (IV&PO) (IDSA)
Shigella - 300 mg twice a day
CLINDAMYCIN (CLEOCIN®)
for 3 days (IDSA)
FOSFOMYCIN (MONUROL®)
Skin infections, uncomplicated -
LEFAMULIN (XENLETA®) 400 mg twice a day for 10 days
OXAZOLIDINONES (PI)
MACROLIDES Urinary tract infection due to E.
coli or K. pneumoniae - 200 mg
NITAZOXANIDE (ALINIA®)
twice a day for 3 days (IDSA,
NITROFURANTOIN (MACROBID®)
PI)
NITROIMIDAZOLES Urinary tract infection due to
PENICILLINS other pathogens - 200 mg twice
a day for 7 days (PI)
QUINOLONES
Urinary tract infections,
RIFAMYCINS complicated - 200 mg twice a
SULFONAMIDES day for 10 days (PI)
TETRACYCLINES
Other
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE May take without regard to food
Antacids, sucralfate, metal
cations (e.g. iron), and
multivitamins may reduce
ofloxacin absorption. Do not

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23/10/2024, 20:43 Antibiotic chart

take within 2 hours of each

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May cause photosensitivity.
ANTIBIOTIC CHART
Limit sun exposure and use
TOP sunscreen.
Liver disease
ACRONYMS
Severe (Child-Pugh C): do
CEPHALOSPORINS
not exceed 400 mg/day
Cefadroxil (Duricef®) 1st Kidney disease
Cephalexin (Keflex®) 1st CrCl 20 - 50 ml/min: usual
Cefaclor (Ceclor®) 2nd dose every 24 hours
Cefprozil (Cefzil®) 2nd CrCl < 20 ml/min: half the
Cefuroxime (Ceftin®) 2nd usual dose every 24 hours
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd
Cefpodoxime (Vantin®) 3rd
Rifamycin
Ceftibuten (Cedax®) 3rd
Aemcolo®
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO)
Dosage forms
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®) Tablet, delayed-release
LEFAMULIN (XENLETA®) 194 mg ($$$$)
Comes in package of 12 tablets
OXAZOLIDINONES
MACROLIDES
Dosing
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®) Adults
Traveler's diarrhea from E. Coli
NITROIMIDAZOLES
- 388 mg (two tablets) twice
PENICILLINS daily for 3 days (PI)
QUINOLONES
RIFAMYCINS Other

SULFONAMIDES Take dose with 6 - 8 ounces of

TETRACYCLINES liquid
DO NOT TAKE with alcohol
OPHTHALMIC ANTIBIOTIC TABLE
May take without regard to food
OTIC ANTIBIOTIC TABLE
Swallow tablets whole. Do not
crush, cut, or chew.
Rifamycin is not effective
against diarrhea complicated
by fever and/or blood in stool or

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23/10/2024, 20:43 Antibiotic chart

diarrhea due to pathogens

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other than E. Coli LOGIN
Rifamycin undergoes minimal
ANTIBIOTIC CHART
systemic absorption and
TOP clinically relevant drug
interactions are not expected
ACRONYMS
Liver disease - given its
CEPHALOSPORINS
minimal absorption, a dose
Cefadroxil (Duricef®) 1st adjustment is not necessary
Cephalexin (Keflex®) 1st Kidney disease - given its
Cefaclor (Ceclor®) 2nd minimal absorption, a dose
Cefprozil (Cefzil®) 2nd adjustment is not necessary
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd
Rifaximin
Cefpodoxime (Vantin®) 3rd
Ceftibuten (Cedax®) 3rd
Xifaxan®
Ceftriaxone (Rocephin®) 3rd
Dosage forms
Ceph generations (IV&PO)
CLINDAMYCIN (CLEOCIN®) Tablet
FOSFOMYCIN (MONUROL®) 200 mg ($$$$)
LEFAMULIN (XENLETA®) 550 mg ($$$$)

OXAZOLIDINONES
Dosing
MACROLIDES
NITAZOXANIDE (ALINIA®) Adults and children ≥ 12 years old
NITROFURANTOIN (MACROBID®) Traveler's diarrhea from E. Coli
- 200 mg three times a day for
NITROIMIDAZOLES
3 days (PI)
PENICILLINS
QUINOLONES Adults (≥ 18 years old)
Hepatic encephalopathy - 550
RIFAMYCINS
mg two times a day (PI)
SULFONAMIDES
Irritable bowel syndrome (IBS)
TETRACYCLINES with diarrhea - 550 mg three
OPHTHALMIC ANTIBIOTIC TABLE times a day for 14 days.
Patients with recurrence may
OTIC ANTIBIOTIC TABLE
be retreated up to two times
with the same regimen. (PI)

Other

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23/10/2024, 20:43 Antibiotic chart

JOIN May take without regard to food

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Rifaximin is not effective
against diarrhea complicated
ANTIBIOTIC CHART
by fever and/or blood in stool or
TOP diarrhea due to pathogens
ACRONYMS other than E. Coli
CEPHALOSPORINS Rifaximin undergoes minimal
systemic absorption and its
Cefadroxil (Duricef®) 1st
effects are thought to be local
Cephalexin (Keflex®) 1st
Rifaximin is a P-glycoprotein
Cefaclor (Ceclor®) 2nd
substrate. P-glycoprotein
Cefprozil (Cefzil®) 2nd
inhibitors may increase
Cefuroxime (Ceftin®) 2nd
systemic exposure. The clinical
Cefdinir (Omnicef®) 3rd
significance of increased
Cefditoren (Spectracef®) 3rd rifaximin exposure is unknown.
Cefixime (Suprax®) 3rd Liver disease
Cefpodoxime (Vantin®) 3rd Mild to moderate (Child-
Ceftibuten (Cedax®) 3rd Pugh A/B): Exposure is
Ceftriaxone (Rocephin®) 3rd increased. No dose
Ceph generations (IV&PO) adjustment recommended.
CLINDAMYCIN (CLEOCIN®) Severe (Child-Pugh C):
FOSFOMYCIN (MONUROL®) Exposure is increased. No
dose adjustment
LEFAMULIN (XENLETA®)
recommended. Use caution.
OXAZOLIDINONES
Kidney disease - has not been
MACROLIDES studied
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®)
NITROIMIDAZOLES
PENICILLINS Sulfadiazine
QUINOLONES
Dosage forms
RIFAMYCINS
SULFONAMIDES Tablet
500 mg ($$$$)
TETRACYCLINES
OPHTHALMIC ANTIBIOTIC TABLE Dosing
OTIC ANTIBIOTIC TABLE
Pediatric (> 2 months old)
Rheumatic fever prophylaxis
Weight ≤ 60 lbs (27 kg): 500
mg once daily

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Weight > 60 lbs (27 kg):

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mg once dailyLOGIN
(AHA/AAP)
ANTIBIOTIC CHART
TOP Adults
Rheumatic fever prophylaxis -
ACRONYMS
1000 mg once daily (AHA)
CEPHALOSPORINS
Cefadroxil (Duricef®) 1st Other
Cephalexin (Keflex®) 1st
Cefaclor (Ceclor®) 2nd Not recommended for the
Cefprozil (Cefzil®) 2nd treatment of group A strep
Cefuroxime (Ceftin®) 2nd infections
Cefdinir (Omnicef®) 3rd Do not use in pregnancy near
Cefditoren (Spectracef®) 3rd term or during nursing. May
Cefixime (Suprax®) 3rd cause kernicterus.
Cefpodoxime (Vantin®) 3rd Liver disease - clearance is
reduced. Use caution.
Ceftibuten (Cedax®) 3rd
Manufacturer makes no
Ceftriaxone (Rocephin®) 3rd
specific recommendation.
Ceph generations (IV&PO)
Kidney disease - clearance is
CLINDAMYCIN (CLEOCIN®)
reduced. Use caution.
FOSFOMYCIN (MONUROL®) Manufacturer makes no
LEFAMULIN (XENLETA®) specific recommendation.
OXAZOLIDINONES
MACROLIDES
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®) Sulfamethoxazole-
NITROIMIDAZOLES Trimethoprim
Septra®, Bactrim®
PENICILLINS
QUINOLONES Dosage forms
RIFAMYCINS
Tablet (Sulfa/TMP)
SULFONAMIDES
800/160 mg (double strength) ($)
TETRACYCLINES 400/80 mg (single strength) ($)
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE Suspension (Sulfa/TMP)
200 mg/40 mg/5 ml ($)

Dosing

Pediatric (≥ 2 months old)

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NOTE: All pediatric dosing based

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NEWSLETTER on trimethoprim LOGIN
component
Bordetella pertussis (treatment
ANTIBIOTIC CHART
or postexposure prophylaxis) -
TOP 8 mg/kg/day given in 2 divided
ACRONYMS doses for 14 days (CDC)
Cellulitis (MRSA coverage) - 8 -
CEPHALOSPORINS
12 mg/kg/day given in 2 divided
Cefadroxil (Duricef®) 1st
doses for 5 - 10 days (IDSA)
Cephalexin (Keflex®) 1st
Cyclospora - 5 mg/kg/day (max
Cefaclor (Ceclor®) 2nd
320 mg/day) given in 2 divided
Cefprozil (Cefzil®) 2nd doses for 3 days (CTE)
Cefuroxime (Ceftin®) 2nd Impetigo
Cefdinir (Omnicef®) 3rd Once daily - 8 mg/kg/day
Cefditoren (Spectracef®) 3rd (max 320 mg/day) given
Cefixime (Suprax®) 3rd once daily for 5 days
Cefpodoxime (Vantin®) 3rd Twice daily - 8 mg/kg/day
Ceftibuten (Cedax®) 3rd (max 320 mg/day) given in
Ceftriaxone (Rocephin®) 3rd two divided doses for 3 days
Ceph generations (IV&PO) [Based on PMID 25172376]
CLINDAMYCIN (CLEOCIN®) Salmonella, nontyphoidal - 10
mg/kg/day (max 320 mg/day)
FOSFOMYCIN (MONUROL®)
given in 2 divided doses for 5 -
LEFAMULIN (XENLETA®)
7 days (IDSA)
OXAZOLIDINONES Shigella - 10 mg/kg/day (max
MACROLIDES 320 mg/day) given in 2 divided
NITAZOXANIDE (ALINIA®) doses for 3 days (IDSA)
Urinary tract infection - 6 - 12
NITROFURANTOIN (MACROBID®)
mg/kg/day (max 320 mg/day)
NITROIMIDAZOLES
given in 2 divided doses for 7 -
PENICILLINS 14 days (CTE)
QUINOLONES Urinary tract infection,
prophylaxis - 2.5 - 3 mg/kg/day
RIFAMYCINS
(max 40 mg/day) given once
SULFONAMIDES daily (CTE)
TETRACYCLINES
Adolescents and adults
OPHTHALMIC ANTIBIOTIC TABLE
Acne - 800/160 twice a day
OTIC ANTIBIOTIC TABLE
(AAP)
Bite, animal -
Sulfamethoxazole-trimethoprim
800/160 twice a day +

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23/10/2024, 20:43 Antibiotic chart

clindamycin 300 mg three

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day; OR LOGIN
metronidazole 250 - 500 mg
ANTIBIOTIC CHART
three times a day (IDSA)
TOP Bordetella pertussis (treatment
or postexposure prophylaxis) -
ACRONYMS
800/160 twice a day for 14
CEPHALOSPORINS
days (CDC)
Cefadroxil (Duricef®) 1st Cellulitis (MRSA coverage) -
Cephalexin (Keflex®) 1st one to two 800/160 tablet(s)
Cefaclor (Ceclor®) 2nd twice a day for 5 - 10 days
Cefprozil (Cefzil®) 2nd (IDSA)
Cefuroxime (Ceftin®) 2nd Cyclospora - 800/160 twice a
Cefdinir (Omnicef®) 3rd day for 7 days (IDSA)
Cefditoren (Spectracef®) 3rd Diabetic foot ulcer (mild, MRSA
Cefixime (Suprax®) 3rd coverage) - one to two 800/160
Cefpodoxime (Vantin®) 3rd tablet(s) twice a day for 7 - 14
Ceftibuten (Cedax®) 3rd days (IDSA)
Ceftriaxone (Rocephin®) 3rd Diverticulitis -
Ceph generations (IV&PO) Sulfamethoxazole-trimethoprim
800/160 twice a day +
CLINDAMYCIN (CLEOCIN®)
metronidazole 500 mg three to
FOSFOMYCIN (MONUROL®)
four times a day for 7 - 14 days
LEFAMULIN (XENLETA®) (CTE)
OXAZOLIDINONES E.Coli, enterotoxigenic -
MACROLIDES 800/160 twice a day for 3 days
(IDSA)
NITAZOXANIDE (ALINIA®)
Prostatitis, acute - 800/160
NITROFURANTOIN (MACROBID®)
twice a day for 2 - 4 weeks
NITROIMIDAZOLES (CTE)
PENICILLINS Prostatitis, chronic - 800/160
twice a day for 4 - 6 weeks
QUINOLONES
(CTE)
RIFAMYCINS Pyelonephritis - 800/160 twice
SULFONAMIDES a day for 14 days; If this
TETRACYCLINES regimen is used empirically,
then also give Ceftriaxone 1000
OPHTHALMIC ANTIBIOTIC TABLE
mg IM one time dose (IDSA)
OTIC ANTIBIOTIC TABLE Salmonella, nontyphoidal -
800/160 twice a day for 5 -7
days (IDSA)
Shigella - 800/160 twice a day
for 3 days (IDSA)

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23/10/2024, 20:43 Antibiotic chart

Urinary tract infection - 800/160

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day for 3 daysLOGIN
(as long
as local resistance rates do not
ANTIBIOTIC CHART
exceed 20%) (IDSA)
TOP Urinary tract infection,
prophylaxis
ACRONYMS
Postcoital - 200/40 one time
CEPHALOSPORINS
postcoital (CTE)
Cefadroxil (Duricef®) 1st Continuous - 200/40 once
Cephalexin (Keflex®) 1st daily OR 200/40 three times
Cefaclor (Ceclor®) 2nd a week (CTE)
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd Other
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd May be taken without regard to
Cefixime (Suprax®) 3rd food
Cefpodoxime (Vantin®) 3rd May cause photosensitivity.
Limit sun exposure and use
Ceftibuten (Cedax®) 3rd
sunscreen.
Ceftriaxone (Rocephin®) 3rd
Trimethoprim may raise
Ceph generations (IV&PO)
potassium levels in susceptible
CLINDAMYCIN (CLEOCIN®)
patients
FOSFOMYCIN (MONUROL®) Trimethoprim is a CYP2C8
LEFAMULIN (XENLETA®) inhibitor and a OCT2 inhibitor
OXAZOLIDINONES and substrate
Sulfamethoxazole is a weak
MACROLIDES
CYP2C9 inhibitor
NITAZOXANIDE (ALINIA®)
Liver disease - do not use in
NITROFURANTOIN (MACROBID®) patients with significant liver
NITROIMIDAZOLES disease
PENICILLINS Kidney disease
CrCL > 30 ml/min: no dose
QUINOLONES
adjustment necessary
RIFAMYCINS CrCl 15 - 30 ml/min: use half
SULFONAMIDES the usual dose
CrCl < 15 ml/min: do not use
TETRACYCLINES
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE

Doxycycline
Acticlate®, Vibramycin®,
Doryx®, Oracea®

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23/10/2024, 20:43 Antibiotic chart

Doxycycline monohydrate
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Tablet
ANTIBIOTIC CHART
50 mg ($)
75 mg ($)
TOP
100 mg ($)
ACRONYMS 150 mg ($$)
CEPHALOSPORINS
Cefadroxil (Duricef®) 1st Capsule
Cephalexin (Keflex®) 1st 50 mg ($)
Cefaclor (Ceclor®) 2nd 75 mg ($$-$$$)
Cefprozil (Cefzil®) 2nd 100 mg ($)
Cefuroxime (Ceftin®) 2nd 150 mg ($$$-$$$$)
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd Capsule (Oracea®)
Cefixime (Suprax®) 3rd 40 mg ($$$$)
Contains 30 mg immediate release and
Cefpodoxime (Vantin®) 3rd
10 mg delayed release
Ceftibuten (Cedax®) 3rd
Ceftriaxone (Rocephin®) 3rd
Suspension
Ceph generations (IV&PO)
25 mg/5 ml ($)
CLINDAMYCIN (CLEOCIN®)
Comes in 60 ml bottle
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®)
Doxycycline hyclate
OXAZOLIDINONES
Capsule
MACROLIDES
50 mg ($)
NITAZOXANIDE (ALINIA®) 100 mg ($)
NITROFURANTOIN (MACROBID®)
NITROIMIDAZOLES Tablet
PENICILLINS 20 mg ($)
50 mg ($$$)
QUINOLONES
75 mg ($)
RIFAMYCINS 100 mg ($)
SULFONAMIDES 150 mg ($$$)

TETRACYCLINES
Tablet (Acticlate®)
OPHTHALMIC ANTIBIOTIC TABLE
75 mg ($$$$)
OTIC ANTIBIOTIC TABLE 150 mg ($$$$)

Tablet, delayed release (Doryx®)

50 mg ($$)
75 mg ($)

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23/10/2024, 20:43 Antibiotic chart

100 mg ($)
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($) LOGIN
200 mg ($$$$)
ANTIBIOTIC CHART
TOP Tablet, delayed release (Doryx® MPC)
60 mg ($$$$)
ACRONYMS
120 mg ($$$$)
CEPHALOSPORINS
Doryx® MPC 120 mg = 100 mg of
Cefadroxil (Duricef®) 1st standard doxycycline, and 60 mg = 50
Cephalexin (Keflex®) 1st mg
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd
Dosing
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd Pediatric (≥ 8 years old)
Cefditoren (Spectracef®) 3rd Pneumonia, community-
Cefixime (Suprax®) 3rd acquired, atypical - 2 - 4
Cefpodoxime (Vantin®) 3rd mg/kg/day given in 2 divided
Ceftibuten (Cedax®) 3rd doses for 7 - 10 days (IDSA)
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO) Adolescents and adults
CLINDAMYCIN (CLEOCIN®) Acne - 50 - 150 mg once daily
or 50 - 100 mg twice a day
FOSFOMYCIN (MONUROL®)
(AAP)
LEFAMULIN (XENLETA®)
Bite, animal - 100 mg twice a
OXAZOLIDINONES day (IDSA)
MACROLIDES Bite, human - 100 mg twice a
day (IDSA)
NITAZOXANIDE (ALINIA®)
Cellulitis (MRSA coverage) -
NITROFURANTOIN (MACROBID®)
100 mg twice a day 5 - 10 days
NITROIMIDAZOLES (IDSA)
PENICILLINS Chlamydia - 100 mg twice a
QUINOLONES day for 7 days (CDC)
Diabetic foot ulcer (mild, MRSA
RIFAMYCINS
coverage) - 100 mg twice a day
SULFONAMIDES for 7 - 14 days (IDSA)
TETRACYCLINES Epididymitis (likely caused by
chlamydia or gonorrhea) -
OPHTHALMIC ANTIBIOTIC TABLE
Ceftriaxone 500 mg IM (1000
OTIC ANTIBIOTIC TABLE
mg if ≥ 330 lbs) single dose +
Doxycycline 100 mg twice daily
for 10 days (CDC)
Malaria prophylaxis - 100 mg
once daily starting 1 - 2 days

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23/10/2024, 20:43 Antibiotic chart

before travel. Continue while in

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region and for 4
weeks after leaving region.
ANTIBIOTIC CHART
[CDC]
TOP Mycoplasma genitalium
Macrolide resistant or
ACRONYMS
unknown: Doxycycline 100
CEPHALOSPORINS
mg twice daily for 7 days,
Cefadroxil (Duricef®) 1st followed by moxifloxacin 400
Cephalexin (Keflex®) 1st mg once daily for 7 days
Cefaclor (Ceclor®) 2nd (CDC)
Cefprozil (Cefzil®) 2nd Macrolide sensitive:
Cefuroxime (Ceftin®) 2nd Doxycycline 100 mg twice
Cefdinir (Omnicef®) 3rd daily for 7 days, followed by
Cefditoren (Spectracef®) 3rd azithromycin 1 gram initial
Cefixime (Suprax®) 3rd dose, followed by 500 mg
Cefpodoxime (Vantin®) 3rd once daily for 3 additional
Ceftibuten (Cedax®) 3rd days (2.5 grams total) (CDC)
Ceftriaxone (Rocephin®) 3rd Pneumonia, community-
Ceph generations (IV&PO) acquired - 100 mg twice a day
for 7 - 14 days (IDSA, CTE)
CLINDAMYCIN (CLEOCIN®)
[3,4]
FOSFOMYCIN (MONUROL®)
Prostatitis, chronic - 100 mg
LEFAMULIN (XENLETA®) twice a day for 4 - 6 weeks
OXAZOLIDINONES (CTE)
MACROLIDES Rosacea (Oracea®) - 40 mg
once daily in the morning on an
NITAZOXANIDE (ALINIA®)
empty stomach (preferably ≥ 1
NITROFURANTOIN (MACROBID®)
hour before or 2 hours after a
NITROIMIDAZOLES meal)
PENICILLINS STD postexposure prophylaxis
- doxycycline hyclate 200 mg
QUINOLONES
delayed-release tablet one time
RIFAMYCINS within 72 hours. [Based on
SULFONAMIDES PMID 37018493]
TETRACYCLINES Sinusitis - 100 mg twice a day
for 7 days (IDSA, PI)
OPHTHALMIC ANTIBIOTIC TABLE
Syphilis (primary and
OTIC ANTIBIOTIC TABLE secondary, pen-allergic) - 100
mg twice a day for 14 days
(CDC)
Syphilis (latent, pen-allergic) -
100 mg twice a day for 28 days

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23/10/2024, 20:43 Antibiotic chart

(CDC)
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Other
ANTIBIOTIC CHART
May be taken without regard to
TOP
food (except Oracea®)
ACRONYMS
Take with full glass of water to
CEPHALOSPORINS reduce risk of esophageal
Cefadroxil (Duricef®) 1st irritation
Cephalexin (Keflex®) 1st Dairy products do not affect
Cefaclor (Ceclor®) 2nd doxycycline absorption
Cefprozil (Cefzil®) 2nd Tetracyclines should not be
Cefuroxime (Ceftin®) 2nd used during the second and
Cefdinir (Omnicef®) 3rd third trimesters of pregnancy,
Cefditoren (Spectracef®) 3rd infancy, and childhood up to 8
Cefixime (Suprax®) 3rd years. All tetracyclines bind
Cefpodoxime (Vantin®) 3rd calcium in tissues, and this can
lead to inhibition of bone
Ceftibuten (Cedax®) 3rd
growth, tooth discoloration
Ceftriaxone (Rocephin®) 3rd
(yellow-gray-brown), and
Ceph generations (IV&PO)
enamel hypoplasia.
CLINDAMYCIN (CLEOCIN®)
Concomitant use of
FOSFOMYCIN (MONUROL®) tetracyclines and isotretinoin
LEFAMULIN (XENLETA®) has been associated with
OXAZOLIDINONES pseudotumor cerebri.
Concurrent use should be
MACROLIDES
avoided.
NITAZOXANIDE (ALINIA®)
May cause photosensitivity.
NITROFURANTOIN (MACROBID®) Limit sun exposure and use
NITROIMIDAZOLES sunscreen.
PENICILLINS Antacids and bismuth
subsalicylate decrease
QUINOLONES
doxycycline bioavailability. Do
RIFAMYCINS not take within 4 hours of each
SULFONAMIDES other.
Kidney disease - no dose
TETRACYCLINES
adjustment necessary
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE

Minocycline
Minocin®, Dynacin®, Solodyn®,

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23/10/2024, 20:43 Antibiotic chart

JOIN Ximino™, Minolira™

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Dosage forms
ANTIBIOTIC CHART
Capsule (Minocin®)
TOP
50 mg ($)
ACRONYMS 75 mg ($)
CEPHALOSPORINS 100 mg ($)
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st Tablet (Dynacin®)
Cefaclor (Ceclor®) 2nd 50 mg ($)
Cefprozil (Cefzil®) 2nd 75 mg ($)
Cefuroxime (Ceftin®) 2nd 100 mg ($)
Cefdinir (Omnicef®) 3rd
Cefditoren (Spectracef®) 3rd Tablet, extended-release (Minolira™)
Cefixime (Suprax®) 3rd 105 mg ($$$$)
Cefpodoxime (Vantin®) 3rd 135 mg ($$$$)
Ceftibuten (Cedax®) 3rd Tablets are scored and may be split
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO) Tablet, extended-release (Solodyn®)
45 mg ($$$)
CLINDAMYCIN (CLEOCIN®)
55 mg ($$-$$$$)
FOSFOMYCIN (MONUROL®)
65 mg ($$$)
LEFAMULIN (XENLETA®) 80 mg ($$$)
OXAZOLIDINONES 90 mg ($$-$$$)
MACROLIDES 105 mg ($$-$$$)
115 mg ($$$)
NITAZOXANIDE (ALINIA®)
135 mg ($$$)
NITROFURANTOIN (MACROBID®)
NITROIMIDAZOLES Capsule, extended-release (Ximino™)
PENICILLINS 45 mg ($$$$)
90 mg ($$$$)
QUINOLONES
135 mg ($$$$)
RIFAMYCINS
SULFONAMIDES Topical
TETRACYCLINES See topical acne antibiotics

OPHTHALMIC ANTIBIOTIC TABLE

OTIC ANTIBIOTIC TABLE Dosing

Minocycline standard-release (≥
12 years old)
Acne - 50 - 100 mg once daily
or 50 - 100 mg twice a day

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(AAP)
JOIN
Straight Healthcare NEWSLETTER CellulitisSUBSCRIBE LOGIN-
(MRSA coverage)
100 mg twice a day 5 - 10 days
ANTIBIOTIC CHART
(IDSA)
TOP
Minolira™ (≥ 12 years old)
ACRONYMS
Acne ∼ 1 mg/kg/day (max 135
CEPHALOSPORINS
mg/day) given once daily.
Cefadroxil (Duricef®) 1st Tablets are scored and may be
Cephalexin (Keflex®) 1st split. (PI)
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd Solodyn® (≥ 12 years old)
Cefuroxime (Ceftin®) 2nd Acne ∼ 1 mg/kg/day (max 135
Cefdinir (Omnicef®) 3rd mg/day) given once daily (PI)
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd Ximino™ (≥ 12 years old)
Cefpodoxime (Vantin®) 3rd Acne ∼ 1 mg/kg/day (max 135
Ceftibuten (Cedax®) 3rd mg/day) given once daily (PI)
Ceftriaxone (Rocephin®) 3rd
Ceph generations (IV&PO) Other
CLINDAMYCIN (CLEOCIN®)
May be taken without regard to
FOSFOMYCIN (MONUROL®) food
LEFAMULIN (XENLETA®) Dairy products do not affect
OXAZOLIDINONES minocycline absorption
Take with full glass of water to
MACROLIDES
reduce risk of esophageal
NITAZOXANIDE (ALINIA®)
irritation
NITROFURANTOIN (MACROBID®) Tetracyclines should not be
NITROIMIDAZOLES used during the second and
PENICILLINS third trimesters of pregnancy,
infancy, and childhood up to 8
QUINOLONES
years. All tetracyclines bind
RIFAMYCINS calcium in tissues, and this can
SULFONAMIDES lead to inhibition of bone
growth, tooth discoloration
TETRACYCLINES
(yellow-gray-brown), and
OPHTHALMIC ANTIBIOTIC TABLE enamel hypoplasia.
OTIC ANTIBIOTIC TABLE Antacids may decrease
bioavailability of minocycline.
Do not take within 4 hours of
each other.

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May cause photosensitivity.

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Limit sun LOGIN
exposure and use
sunscreen.
ANTIBIOTIC CHART
Concomitant use of
TOP tetracyclines and isotretinoin
has been associated with
ACRONYMS
pseudotumor cerebri.
CEPHALOSPORINS
Concurrent use should be
Cefadroxil (Duricef®) 1st avoided.
Cephalexin (Keflex®) 1st May cause hyperpigmentation
Cefaclor (Ceclor®) 2nd around scars, shins, and
Cefprozil (Cefzil®) 2nd mucous membranes with
Cefuroxime (Ceftin®) 2nd prolonged use
Cefdinir (Omnicef®) 3rd Liver disease - use caution.
Cefditoren (Spectracef®) 3rd Manufacturer makes no
Cefixime (Suprax®) 3rd specific recommendation.
Cefpodoxime (Vantin®) 3rd Kidney disease - has not been
Ceftibuten (Cedax®) 3rd studied. Manufacturer makes
Ceftriaxone (Rocephin®) 3rd no specific recommendation.
Ceph generations (IV&PO)
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Omadacycline
OXAZOLIDINONES Nuzyra®
MACROLIDES
Dosage forms
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®) Tablet
NITROIMIDAZOLES 150 mg ($$$$)

PENICILLINS
Dosing
QUINOLONES
Adults
RIFAMYCINS
Cellulitis (MRSA coverage) -
SULFONAMIDES
450 mg once daily for 2 days
TETRACYCLINES followed by 300 mg once daily
OPHTHALMIC ANTIBIOTIC TABLE for a total of 7 - 14 days (PI)
Pneumonia, community-
OTIC ANTIBIOTIC TABLE
acquired - 300 mg twice on day
1 then 300 mg once daily for a
total of 7 - 14 days (PI)

Other
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JOIN Fast for at least 4 hours and

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then take with water. After oral
dosing, no food or drink (except
ANTIBIOTIC CHART
water) is to be consumed for 2
TOP hours and no dairy products,
ACRONYMS antacids, or multivitamins for 4
CEPHALOSPORINS hours.
Tetracyclines should not be
Cefadroxil (Duricef®) 1st
used during the second and
Cephalexin (Keflex®) 1st
third trimesters of pregnancy,
Cefaclor (Ceclor®) 2nd
infancy, and childhood up to 8
Cefprozil (Cefzil®) 2nd
years. All tetracyclines bind
Cefuroxime (Ceftin®) 2nd
calcium in tissues, and this can
Cefdinir (Omnicef®) 3rd
lead to inhibition of bone
Cefditoren (Spectracef®) 3rd growth, tooth discoloration
Cefixime (Suprax®) 3rd (yellow-gray-brown), and
Cefpodoxime (Vantin®) 3rd enamel hypoplasia.
Ceftibuten (Cedax®) 3rd May cause photosensitivity.
Ceftriaxone (Rocephin®) 3rd Limit sun exposure and use
Ceph generations (IV&PO) sunscreen.
CLINDAMYCIN (CLEOCIN®) Concomitant use of
FOSFOMYCIN (MONUROL®) tetracyclines and isotretinoin
has been associated with
LEFAMULIN (XENLETA®)
pseudotumor cerebri.
OXAZOLIDINONES
Concurrent use should be
MACROLIDES avoided.
NITAZOXANIDE (ALINIA®) Liver disease - no dose
adjustment necessary
NITROFURANTOIN (MACROBID®)
Kidney disease - no dose
NITROIMIDAZOLES
adjustment necessary
PENICILLINS
QUINOLONES
RIFAMYCINS
SULFONAMIDES Sarecycline
TETRACYCLINES Seysara™
OPHTHALMIC ANTIBIOTIC TABLE
Dosage forms
OTIC ANTIBIOTIC TABLE
Tablet
60 mg ($$$$)
100 mg ($$$$)
150 mg ($$$$)

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Dosing
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Children ≥ 9 years old and adults
ANTIBIOTIC CHART
Acne
33 - 54 kg: 60 mg once daily
TOP
55 - 84 kg: 100 mg once
ACRONYMS daily
CEPHALOSPORINS 85 - 136 kg: 150 mg once
Cefadroxil (Duricef®) 1st daily (PI)
Cephalexin (Keflex®) 1st
Cefaclor (Ceclor®) 2nd Other
Cefprozil (Cefzil®) 2nd
May take without regard to food
Cefuroxime (Ceftin®) 2nd
Take with full glass of water to
Cefdinir (Omnicef®) 3rd
reduce risk of esophageal
Cefditoren (Spectracef®) 3rd
irritation
Cefixime (Suprax®) 3rd
Tetracyclines should not be
Cefpodoxime (Vantin®) 3rd
used during the second and
Ceftibuten (Cedax®) 3rd
third trimesters of pregnancy,
Ceftriaxone (Rocephin®) 3rd
infancy, and childhood up to 8
Ceph generations (IV&PO) years. All tetracyclines bind
CLINDAMYCIN (CLEOCIN®) calcium in tissues, and this can
FOSFOMYCIN (MONUROL®) lead to inhibition of bone
LEFAMULIN (XENLETA®) growth, tooth discoloration
(yellow-gray-brown), and
OXAZOLIDINONES
enamel hypoplasia.
MACROLIDES
May cause photosensitivity.
NITAZOXANIDE (ALINIA®) Limit sun exposure and use
NITROFURANTOIN (MACROBID®) sunscreen.
NITROIMIDAZOLES Antacids may decrease
bioavailability of sarecycline.
PENICILLINS
Do not take within 4 hours of
QUINOLONES each other.
RIFAMYCINS Concomitant use of
tetracyclines and isotretinoin
SULFONAMIDES
has been associated with
TETRACYCLINES pseudotumor cerebri.
OPHTHALMIC ANTIBIOTIC TABLE Concurrent use should be
OTIC ANTIBIOTIC TABLE avoided.
Sarecycline is a P-glycoprotein
inhibitor
Liver disease
Child-Pugh A/B: no dose
adjustment necessary
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23/10/2024, 20:43 Antibiotic chart

Child-Pugh C: has not been

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studied
Kidney disease - manufacturer
ANTIBIOTIC CHART
states that "renal impairment"
TOP has no clinically significant
ACRONYMS effect on pharmacokinetics, but
it has not been studied in end-
CEPHALOSPORINS
stage renal disease
Cefadroxil (Duricef®) 1st
Cephalexin (Keflex®) 1st
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd Tetracycline
Cefdinir (Omnicef®) 3rd Achromycin V®
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd Dosage forms
Cefpodoxime (Vantin®) 3rd
Capsule
Ceftibuten (Cedax®) 3rd
250 mg ($$-$$$)
Ceftriaxone (Rocephin®) 3rd
500 mg ($$-$$$)
Ceph generations (IV&PO)
CLINDAMYCIN (CLEOCIN®)
Dosing
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®) Adolescents and adults
Acne - 500 mg twice a day
OXAZOLIDINONES
(AAP)
MACROLIDES
H. pylori treatment regimens
NITAZOXANIDE (ALINIA®) Syphilis (primary and
NITROFURANTOIN (MACROBID®) secondary, pen-allergic) - 500
NITROIMIDAZOLES mg four times a day for 14 days
(CDC)
PENICILLINS
Syphilis (latent, pen-allergic) -
QUINOLONES 500 mg four times a day for 28
RIFAMYCINS days (CDC)

SULFONAMIDES
Other
TETRACYCLINES
OPHTHALMIC ANTIBIOTIC TABLE Take at least 1 hour before food
OTIC ANTIBIOTIC TABLE or two hours after
Dairy products taken at the
same time as tetracycline may
decrease absorption
Take with full glass of water to
reduce risk of esophageal
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23/10/2024, 20:43 Antibiotic chart

irritation
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Tetracyclines LOGIN
should not be
used during the second and
ANTIBIOTIC CHART
third trimesters of pregnancy,
TOP infancy, and childhood up to 8
years. All tetracyclines bind
ACRONYMS
calcium in tissues, and this can
CEPHALOSPORINS
lead to inhibition of bone
Cefadroxil (Duricef®) 1st growth, tooth discoloration
Cephalexin (Keflex®) 1st (yellow-gray-brown), and
Cefaclor (Ceclor®) 2nd enamel hypoplasia.
Cefprozil (Cefzil®) 2nd Antacids may decrease
Cefuroxime (Ceftin®) 2nd bioavailability of tetracycline.
Cefdinir (Omnicef®) 3rd Do not take within 4 hours of
Cefditoren (Spectracef®) 3rd each other.
Cefixime (Suprax®) 3rd May cause photosensitivity.
Cefpodoxime (Vantin®) 3rd Limit sun exposure and use
Ceftibuten (Cedax®) 3rd sunscreen.
Ceftriaxone (Rocephin®) 3rd Concomitant use of
Ceph generations (IV&PO) tetracyclines and isotretinoin
has been associated with
CLINDAMYCIN (CLEOCIN®)
pseudotumor cerebri.
FOSFOMYCIN (MONUROL®)
Concurrent use should be
LEFAMULIN (XENLETA®) avoided.
OXAZOLIDINONES Liver disease - manufacturer
MACROLIDES makes no specific
recommendation
NITAZOXANIDE (ALINIA®)
Kidney disease - dose
NITROFURANTOIN (MACROBID®)
reduction recommended.
NITROIMIDAZOLES Manufacturer makes no
PENICILLINS specific recommendation.

QUINOLONES
RIFAMYCINS
SULFONAMIDES
PRICE ($) INFO
TETRACYCLINES
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE $ = 0 - $50
$$ = $51 - $100
$$$ = $101 - $150
$$$$ = > $151

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23/10/2024, 20:43 Antibiotic chart

? = Pricing not found.

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Availability LOGIN
may be limited.

ANTIBIOTIC CHART
Pricing based on one course of
TOP therapy at standard dosing in
an adult
ACRONYMS
Pricing based on information
CEPHALOSPORINS
from GoodRX.com®
Cefadroxil (Duricef®) 1st Pricing may vary by region and
Cephalexin (Keflex®) 1st availability
Cefaclor (Ceclor®) 2nd
Cefprozil (Cefzil®) 2nd
Cefuroxime (Ceftin®) 2nd
Cefdinir (Omnicef®) 3rd
BIBLIOGRAPHY
Cefditoren (Spectracef®) 3rd
Cefixime (Suprax®) 3rd 1 - PMID 24918220
Cefpodoxime (Vantin®) 3rd 2 - PMID 8666093
Ceftibuten (Cedax®) 3rd 3 - PMID 20456738 Doxy trial in CAP
Ceftriaxone (Rocephin®) 3rd 4 - PMID 9989538 Doxy trial in CAP
Ceph generations (IV&PO)
CLINDAMYCIN (CLEOCIN®)
FOSFOMYCIN (MONUROL®)
LEFAMULIN (XENLETA®)
OXAZOLIDINONES
MACROLIDES
NITAZOXANIDE (ALINIA®)
NITROFURANTOIN (MACROBID®)
NITROIMIDAZOLES
PENICILLINS
QUINOLONES
RIFAMYCINS
SULFONAMIDES
TETRACYCLINES
OPHTHALMIC ANTIBIOTIC TABLE
OTIC ANTIBIOTIC TABLE

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