SAPTHAGIRI INSTITUTE OF MEDICAL SCIENCES AND RESEARCH CENTRE
DEPARTMENT OF PHYSIOLOGY
I MBBS 2024-25 Batch
ASSIGNMENT -16
I. Long Essay 1X10 = 10 Marks
1. Name the respiratory centers. Explain the neural regulation of respiration. What is
apneusis? Add a note on Ondine’s curse.
II. Reasoning Questions 2X3 = 6 Marks
2. Explain why the alveoli remain dry.
3. Explain why Tuberculous bacilli tend to grow in the apical regions of the lungs.
III. Short Notes (Applied aspects) 2X5 = 10 Marks
4. Explain Infant Respiratory Distress Syndrome. Add a note on pulmonary surfactant.
5. What is Timed Vital capacity? How is it measured? Give its importance as lung function
test
V. Short Essays 2X6 = 12 Marks
6. Describe oxygen dissociation curve with a neat labelled diagram and factors affecting it.
Give the significance of its shape.
7. What is anatomical and physiological dead space? Describe one method to measure
anatomical dead space
VI. Short Notes 1X5 = 5 Marks
8. Classify and explain ‘Hypoxia’. Give examples for each type. Mention distinguishing
features of each type of hypoxia.
P.T.O.
I. Multiple Choice Questions 7X1 = 7 Marks
9. A healthy, 45-year-old man is reading the newspaper. Which of the following muscles are used for
quiet breathing?
A) Diaphragm and external intercostals B) Diaphragm and internal intercostals
C) Diaphragm only D) Internal intercostals and abdominal recti
10. The pleural pressure of a normal 56-year-old woman is approximately −2.5 mm Hg during resting
conditions immediately before inspiration (i.e., at functional residual capacity). What is the pleural
pressure during inspiration?
A) +1 mm Hg B) +4 mm Hg
C) 0 mm Hg D) −6 mm Hg
11. A patient has a dead space of 150 ml, functional residual capacity of 3 L, tidal volume of 650 ml,
Expiratory reserve volume of 1.5 L, a total lung capacity of 8 L, respiratory rate of 15 breaths/min.
What is the alveolar ventilation?
A) 5 L/min B) 7.5 L/min
C) 6.0 L/min D) 9.0 L/min
12. Which of the following gases is often used to estimate the oxygen diffusing capacity of the lungs?
A) Carbon dioxide B) Carbon monoxide
C) Cyanide gas D) Nitrogen
13. One of the following does not stimulate peripheral chemoreceptors:
A) Hypoxia B) Hypocapnia
C) Acidosis D) Low perfusion pressure
14. At a fraternity party a 17-year-old male places a paper bag over his mouth and breathes in and out
of the bag. As he continues to breathe into this bag, his breathing rate continues to increase. Which of
the following is responsible for the increased ventilation?
A) Increased alveolar Po2 B) Increased alveolar Pco2
C) Decreased arterial Pco2 D) Increased pH
15. Oxygen therapy is most beneficial in which of the following situations? Lung function is normal.
A) Anemia B) CO2 retention (COPD)
C) Cyanide poisoning D) High altitude
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