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Interphase

The cell cycle consists of a series of events leading to cell maturity and division, including genome duplication and organelle synthesis. It is divided into two main phases: interphase, which occupies about 95% of the cycle and includes G1, S, and G2 phases, and the mitotic phase. Some cells enter a quiescent G0 phase where they remain metabolically active but do not divide unless necessary.

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9 views2 pages

Interphase

The cell cycle consists of a series of events leading to cell maturity and division, including genome duplication and organelle synthesis. It is divided into two main phases: interphase, which occupies about 95% of the cycle and includes G1, S, and G2 phases, and the mitotic phase. Some cells enter a quiescent G0 phase where they remain metabolically active but do not divide unless necessary.

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rjsanchez
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Phases of Cell Cycle

Cell cycle or cell division refers to the series of events that take place
in a cell leading to its maturity and subsequent division. These events
include duplication of its genome and synthesis of the cell organelles
followed by division of the cytoplasm.

Human cells exhibit typical eukaryotic cell cycle and take around 24
hours to complete one cycle of growth and division. The duration of
the cycle, however, varies from organism to organism and cell to cell.

A typical eukaryotic cell cycle is divided into two main phases:-

Interphase
Also known as the resting phase of the cell cycle; interphase is the
time during which the cell prepares for division by undergoing both
cell growth and DNA replication. It occupies around 95% time of the
overall cycle. The interphase is divided into three phases:-

•G1 phase (Gap 1)– G1phase is the phase of the cell between
mitosis and initiation of replication of the genetic material of the
cell. During this phase, the cell is metabolically active and
continues to grow without replicating its DNA.
•S phase (Synthesis)– DNA replication takes place during this
phase. If the initial quantity of DNA in the cell is denoted as2N,
then after replication it becomes4N. However the number of
chromosomes does not vary, viz. The centriole also divides into
two centriole pairs in the cells which contain centriole.
•G2 phase (Gap 2)–During this phase, the RNA, proteins, other
macromolecules required for multiplication of cell organelles,
spindle formation, and cell growth are produced as the cell
prepares to go into the mitotic phase.
Some cells like cardiac cells in the adult animals do not exhibit division
and some others only divide to replace those cells which have been
either damaged or lost due to cell death. Such cells which do not
divide further attain an inactive G0 phase also known as quiescent
phase after they exit the G1 phase. These cells remain metabolically
active but do not divide unless called upon to do so.

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