LGC Mikromol™

Explore our exclusive offer on 2,500+ TRC research chemicals and analytical standards, now available at up to 80% off. Discover the savings: https://ow.ly/JBic50XfEYs Designed to support every stage of pharmaceutical development, from impurity profiling to formulation and QC, this discounted range includes: ✔ APIs and metabolites ✔ Impurities and isotope-labelled compounds #PharmaResearch #DrugDiscovery #ImpurityAnalysis #ReferenceStandards Toronto Research Chemicals

How do common tablet excipients contribute to nitrosamine formation? 💊 Our latest on-demand webinar explores how excipients such as dicalcium phosphate and microcrystalline cellulose can introduce residual nitrites - driving N-nitroso-sertraline formation that, in some cases, exceeds daily intake limits. ▶️ Watch the full session on demand now: https://ow.ly/cj6E50Xf6ew #Webinar #NDSRIs #NitrosamineAnalysis #PharmaResearch #DrugSafety

📢Save the date for our upcoming webinar: Upcoming Webinar: Evaluating Drug–Drug Interactions – A Framework from Lab to Clinic Join Professor Tore B. Stage, Head of Research and Professor of Clinical Pharmacology, Pharmacy and Environmental Medicine at the University of Southern Denmark, as he shares how complementary methods: from hepatocyte cultures and qPCR to LC–MS/MS and real-world studies - can form an integrated framework for evaluating DDIs. 💡 What you’ll learn: ✔ Recognise the clinical impact of DDIs and their role in adverse outcomes ✔ Understand how complementary methods integrate to evaluate DDIs ✔ Apply insights from isoxazolyl penicillins as a transferable case study 📅 November 12 | 11:00 EST / 8:00 PST / 16:00 GMT / 17:00 CET 🔗 Register now to save your spot: https://ow.ly/iH2O50Xf0Ax #Webinar #DrugInteractions #PharmaResearch #DDI #DrugDevelopment C&EN American Chemical Society

More than half of our recent webinar attendees agreed:👉 Method sensitivity is the biggest challenge in nitrosamine risk assessment. If you’re facing the same issue, you’re not alone - and there are proven ways to overcome it. 🎥 Watch our on-demand webinar, Mastering Trace-Level Nitrosamine Detection: Pitfalls & Proven Solutions, to explore real-world case studies and practical strategies for more accurate, reliable analysis. https://ow.ly/hjzu50XaA7e #Webinar #NDSRIs #NitrosamineAnalysis #pharma

The wide range of nitrosamine contaminants poses a major challenge for quality scientists developing sensitive, reliable detection methods. ▶️In this on-demand webinar, we outline the process for building a new analytical method — from analytical setup through to validation — illustrated with the example analyte N-nitroso-sertraline. Watch the webinar here: https://ow.ly/P8pk50X6n9z #Webinar #NDSRIs #NitrosamineAnalysis #pharma

🧠💊 #PharmaQuiz Ropinirole is a prescription medicine used to manage Parkinson’s disease and restless legs syndrome. It’s been an important tool for improving motor control and quality of life. But one of its side effects has caught clinicians’ attention… 💭Which surprising side effect has been linked to ropinirole? Drop your guess in the comments ⬇️ We'll reveal the answer next week!

Looking to expand your inventory or stock up on trusted compounds? Explore over 2,500 high-quality Toronto Research Chemicals products - now available at up to 80% off! Our discounted portfolio supports the full pharmaceutical lifecycle, including: ✔ Impurities ✔ Metabolites ✔ APIs ✔ Stable isotope-labelled compounds View the new flyer: https://ow.ly/4bXn50X4PWZ #PharmaResearch #DrugDiscovery #ImpurityAnalysis #ReferenceStandards

👇This diagram highlights the key factors driving nitrosamine formation, alongside practical strategies to mitigate them. For more details, download our latest whitepaper, "Nitrosamine formation in pharmaceuticals – pathways and prevention strategies" https://ow.ly/3A1U50X2VWA #Nitrosamines #NDSRIs #PharmaceuticalDevelopment #DrugSafety #RegulatoryCompliance

Missed our live webinar “Mastering Trace-Level Nitrosamine Detection: Pitfalls & Proven Solutions”? You can now watch it on demand! ▶️https://ow.ly/Rsej50X0cFf This session dives into real-world case studies showing how to overcome common pitfalls in nitrosamine analysis: 1) N-nitroso-sertraline – In partnership with Waters Corporation, we developed a sensitive UPLC–MS/MS method, addressing pitfalls like in-sample nitrosation. 2) Rifampin and rifapentine – How matrix effects masked an out-of-spec result, and how stable isotope-labelled standards, LC optimisation, and standard addition resolved it. Don’t miss this chance to hear from experts and take away proven solutions for your lab. #Webinar #NDSRIs #NitrosamineAnalysis #pharma

From biomarkers to organ-on-a-chip models, new tools are transforming how we predict toxicity and drug–drug interaction (DDI). Download the full white paper for practical guidance aligned with ICH M12: https://ow.ly/aKcR50X07P5 #DrugDevelopment #DDI #PBPK #ICHM12