Tomocube, Inc.

🔥[𝗣𝘂𝗯𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗵𝗶𝗴𝗵𝗹𝗶𝗴𝗵𝘁] 𝗖𝗿𝗮𝗰𝗸𝗶𝗻𝗴 𝗖𝗮𝗻𝗰𝗲𝗿’𝘀 𝗖𝗼𝗽𝗽𝗲𝗿 𝗖𝗼𝗱𝗲 Copper metabolism plays a pivotal role in tumor growth and cancer progression. A new study published in 𝘼𝙙𝙫𝙖𝙣𝙘𝙚𝙙 𝙃𝙚𝙖𝙡𝙩𝙝𝙘𝙖𝙧𝙚 𝙈𝙖𝙩𝙚𝙧𝙞𝙖𝙡𝙨  shows that 𝗬𝗔𝗣 𝗼𝘃𝗲𝗿𝗲𝘅𝗽𝗿𝗲𝘀𝘀𝗶𝗼𝗻 𝗺𝗮𝗸𝗲𝘀 𝗯𝗿𝗲𝗮𝘀𝘁 𝗰𝗮𝗻𝗰𝗲𝗿 𝗰𝗲𝗹𝗹𝘀 𝘃𝘂𝗹𝗻𝗲𝗿𝗮𝗯𝗹𝗲 𝘁𝗼 𝗰𝘂𝗽𝗿𝗼𝗽𝘁𝗼𝘀𝗶𝘀—𝗮 𝗳𝗼𝗿𝗺 𝗼𝗳 𝗰𝗲𝗹𝗹 𝗱𝗲𝗮𝘁𝗵 𝘁𝗿𝗶𝗴𝗴𝗲𝗿𝗲𝗱 𝗯𝘆 𝗰𝗼𝗽𝗽𝗲𝗿 𝗼𝘃𝗲𝗿𝗹𝗼𝗮𝗱—𝘃𝗶𝗮 𝘁𝗵𝗲 𝗬𝗔𝗣–𝗔𝗧𝗢𝗫𝟭 𝗮𝘅𝗶𝘀. This vulnerability is amplified with melatonin-powered copper nanomaterials, which suppress tumor growth, block metastasis, and enhance immunity. 🔬 Using holotomography, the team captured label-free, real-time 3D evidence of #mitochondrial disruption, validating cuproptosis as a therapeutic pathway in living cancer cells. https://lnkd.in/gh-NHgrB #HolotomographyPublication #tomocube #publication #3Dimaging #livecellimaging #cuproptosis #breastcancer #cancerresearch #holotomography #precisionmedicine #nanotherapy

👻 Something’s spooky in the lab tonight... Our HT systems are out haunting — under the watchful spheroid moon, while the phacus have found their true calling as pumpkins. 🎃✨ Happy Halloween — stay spooky, stay label-free!

Tomocube is exhibiting at the 𝗚𝗹𝗼𝗕𝗜𝗔𝗦 𝗕𝗶𝗼𝗶𝗺𝗮𝗴𝗲 𝗔𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝗖𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 𝟮𝟬𝟮𝟱 in 𝗞𝗼𝗯𝗲, 𝗝𝗮𝗽𝗮𝗻, together with our distributor Shinkouseiki! We’ll be on site through the end of the week (Oct 31) — stop by our booth to connect with the team and explore Tomocube’s 𝗵𝗼𝗹𝗼𝘁𝗼𝗺𝗼𝗴𝗿𝗮𝗽𝗵𝘆 𝗮𝗻𝗱 𝗔𝗜-𝗽𝗼𝘄𝗲𝗿𝗲𝗱 𝗧𝗼𝗺𝗼𝗔𝗻𝗮𝗹𝘆𝘀𝗶𝘀 solutions for quantitative 3D live-cell and tissue imaging. #Tomocube #TomoAnalysis #GloBIAS2025 #BioimageAnalysis #3DImaging

🎉 Congratulations to the 𝗨𝗻𝗶𝘃𝗲𝗿𝘀𝗶𝘁𝘆 𝗼𝗳 𝗢𝘀𝗹𝗼 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝘁𝗲𝗮𝗺 on their recent publication in 𝘍𝘳𝘰𝘯𝘵𝘪𝘦𝘳𝘴 𝘪𝘯 𝘊𝘦𝘭𝘭 𝘢𝘯𝘥 𝘋𝘦𝘷𝘦𝘭𝘰𝘱𝘮𝘦𝘯𝘵𝘢𝘭 𝘉𝘪𝘰𝘭𝘰𝘨𝘺, reporting new findings in liver endothelial biology and showing how Tomocube’s HT-X1 enables 𝗹𝗮𝗯𝗲𝗹-𝗳𝗿𝗲𝗲, 𝗹𝗼𝗻𝗴-𝘁𝗲𝗿𝗺 𝟯𝗗 𝘁𝗿𝗮𝗰𝗸𝗶𝗻𝗴 𝗼𝗳 𝗵𝘂𝗺𝗮𝗻 𝘀𝘁𝗲𝗺 𝗰𝗲𝗹𝗹–𝗱𝗲𝗿𝗶𝘃𝗲𝗱 𝗹𝗶𝘃𝗲𝗿 𝘀𝗶𝗻𝘂𝘀𝗼𝗶𝗱𝗮𝗹 𝗲𝗻𝗱𝗼𝘁𝗵𝗲𝗹𝗶𝗮𝗹 𝗰𝗲𝗹𝗹𝘀 (𝘀𝗰𝗟𝗦𝗘𝗖𝘀). Using quantitative holotomography, the authors continuously monitored pore-like (low-RI) membrane structures—a hallmark of LSEC morphology—without fixation or fluorescent labeling. These structures were analyzed over time using a machine learning–based algorithm, revealing dynamic changes linked to cell differentiation and culture conditions. The work further demonstrated that exposure to zone-specific culture environments (Z1/Z3) induced directional changes in LSEC markers, metabolism, and morphology, highlighting the potential of scLSECs as an in vitro model for liver zonation. 🔬 From a technology standpoint, this study shows that HT-X1 can non-invasively capture fine transcellular structures in live cells over the long term, providing dynamic, label-free data for 𝗿𝗲𝗽𝗲𝗮𝘁𝗲𝗱 𝗮𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝗼𝗳 𝗰𝗲𝗹𝗹 𝗺𝗮𝘁𝘂𝗿𝗮𝘁𝗶𝗼𝗻, 𝗱𝗿𝘂𝗴 𝗿𝗲𝘀𝗽𝗼𝗻𝘀𝗲𝘀, 𝗮𝗻𝗱 𝗱𝗶𝘀𝗲𝗮𝘀𝗲 𝗺𝗼𝗱𝗲𝗹𝘀, beyond what conventional SEM or fluorescence microscopy can offer. #HolotomographyPublication #tomocube #publication #3Dimaging #livecellimaging #Stemcell #Livercell #Hepatocyte #LSEC, ##pluripotentstemcell #PSC, #liverzonation 

👏 Huge congratulations to Prof. Seongsoo Lee’s team on their latest breakthrough published in the Journal of Hazardous Materials! By 𝗶𝗻𝘁𝗲𝗴𝗿𝗮𝘁𝗶𝗻𝗴 𝗵𝗼𝗹𝗼𝘁𝗼𝗺𝗼𝗴𝗿𝗮𝗽𝗵𝘆 𝘄𝗶𝘁𝗵 𝗹𝗶𝗽𝗶𝗱𝗼𝗺𝗶𝗰𝘀 𝗮𝗻𝗱 𝘁𝗿𝗮𝗻𝘀𝗰𝗿𝗶𝗽𝘁𝗼𝗺𝗶𝗰𝘀, the study reveals how airborne particulate matter (PM) hijacks macrophages—activating the Lands cycle and driving inflammation through lipid remodeling, offering new clues to how pollution fuels chronic disease. Potential lipid biomarkers are also proposed for monitoring PM-induced inflammation. With label-free, real-time 3D imaging, 𝗵𝗼𝗹𝗼𝘁𝗼𝗺𝗼𝗴𝗿𝗮𝗽𝗵𝘆 𝗲𝗻𝗮𝗯𝗹𝗲𝗱 𝗱𝗶𝗿𝗲𝗰𝘁 𝘃𝗶𝘀𝘂𝗮𝗹𝗶𝘇𝗮𝘁𝗶𝗼𝗻 𝗼𝗳 𝗽𝗮𝗿𝘁𝗶𝗰𝗹𝗲 𝘂𝗽𝘁𝗮𝗸𝗲 𝗮𝗻𝗱 𝗹𝗶𝗽𝗶𝗱 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗶𝗻 𝗹𝗶𝘃𝗶𝗻𝗴 𝗰𝗲𝗹𝗹𝘀, uncovering fresh insights into PM-induced immune–metabolic dysfunction. https://lnkd.in/g52qXvEu #HolotomographyPublication #tomocube #publication #3Dimaging #livecellimaging #PM #particulatematter #lipid #lipiddroplet #lipidmetabolism #macrophage 

We’re excited to be back in Heidelberg for the EMBO | EMBL Symposium: Organoids: Modelling organ development and disease in 3D, organized by EMBL Events!! Join us at #EESORgan to explore how Tomocube’s #holotomography technology enables label-free, quantitative 3D imaging and analysis of organoids — revealing their complex 3D structures and dynamics, in high resolution and without compromising cell viability.

We’re thrilled to see 𝗙𝗼𝗿𝗯𝗲𝘀 𝗙𝗿𝗮𝗻𝗰𝗲 spotlighting Tomocube’s revolutionary 3D imaging technology and its impact on precision medicine! In this article, Bruno Combettes, our EMEA Director, shares his insights on how label-free holotomography and AI-driven analysis are reshaping cancer research and fertility medicine across Europe and beyond. Seeing the unseen — Read the article now to see how science and innovation come together to advance healthcare. 👇 #Tomocube #Holotomography #3DImaging #AI #PrecisionMedicine #CancerResearch #IVF #Innovation #ForbesFrance

🎥 See the 𝗛𝗧-𝗫𝟭 𝗺𝗶𝗻𝗶 𝗪𝗼𝗿𝗸𝗳𝗹𝗼𝘄 in Action Join our sales manager, DJ Shin, as he walks you through the full X1 mini workflow—from loading the sample to imaging and analysis. This short video shows how the system is designed for seamless, fast operation, 𝗹𝗲𝘁𝘁𝗶𝗻𝗴 𝘆𝗼𝘂 𝗳𝗼𝗰𝘂𝘀 𝗼𝗻 𝘆𝗼𝘂𝗿 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵, 𝗻𝗼𝘁 𝘁𝗵𝗲 𝘀𝗲𝘁𝘂𝗽. Watch now 👇 #Tomocube #X1series #X1Mini #Holotomography

📢 New 𝗖𝗮𝘀𝗲 𝗦𝘁𝘂𝗱𝘆 featured in our October newsletter! In collaboration with Okomera and the research team at Institut Gustave Roussy, our study highlights how Tomocube’s #holotomography technology, when integrated with Okomera’s droplet-based #microfluidics, enables detailed, label-free analysis of chemotherapy response in patient-derived organoids (PDOs). 📩 Read the full story in our newsletter 👇

🎙 𝗦𝗽𝗲𝗰𝗶𝗮𝗹 𝗚𝘂𝗲𝘀𝘁 𝗟𝗲𝗰𝘁𝘂𝗿𝗲 𝗔𝗻𝗻𝗼𝘂𝗻𝗰𝗲𝗺𝗲𝗻𝘁 We are pleased to invite you to a special lecture by 𝗣𝗿𝗼𝗳𝗲𝘀𝘀𝗼𝗿 𝗠𝗮𝗿𝗰𝘂𝘀 𝗖𝗼𝗻𝗿𝗮𝗱 on 𝗧𝗵𝘂𝗿𝘀𝗱𝗮𝘆, 𝗢𝗰𝘁𝗼𝗯𝗲𝗿 𝟮𝟯, at 1:30 PM (KST), to be held in the Sangmin Room at Tomocube HQ. Professor Conrad is a world-renowned expert in 𝗰𝗲𝗹𝗹 𝗱𝗲𝗮𝘁𝗵 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵, best known for his pioneering discovery of ferroptosis, a unique form of regulated cell death. We are truly honored to host him for this in-person session at our headquarters. 🔗 About Professor Conrad: https://lnkd.in/dXJbTYQA This is a rare opportunity to hear directly from one of the foremost scientists in the field. External guests will also be attending, so please send us a request email in advance to help us with arrangements. We look forward to your participation in this inspiring session. #Ferroptosis #CellDeath #Seminar #Tomocube #LifeScience