Agios Pharmaceuticals

This week, we attended the #NORDSummit, hosted by the National Organization for Rare Disorders (NORD), where our Chief Medical Officer and Head of R&D, Dr. Sarah Gheuens, joined Golie-Lorenzo Green, a sickle cell warrior and advocate, to share learnings from co-creating the RISE UP clinical program in #SickleCellDisease with the community. The session highlighted what it means to truly center patients in research: ✨ Going beyond a rubber stamp, by engaging patients before the first protocol is even drafted and keeping their voices central from design through to awareness and communication. 💬 Showing the impact of patient feedback through transparency about how input was used, and when it couldn’t be, why. That honesty built trust and lasting partnerships. 🤝 Proving what’s possible when science and community rise up together. Thank you to NORD for hosting another impactful conference and inviting us to share our experience and insights with the #RareDisease community.

Our team had the privilege of joining the #SCDAA2025 National Convention last week, a powerful gathering of #SickleCell warriors, advocates, clinicians, and partners. Every year, this event feels less like a conference and more like a reunion – a reminder of the strength, resilience, and power of this community driving progress in care and advocacy. During the convention, we: ✨ Met with partners to explore new ways to support innovation that reflects real community needs 🧬 Presented on the potential of pyruvate kinase (PK) activation in sickle cell disease 🎙️ Hosted and recorded an episode of “Cheat Codes: A Sickle Cell Podcast” exploring how sickle cell disease is portrayed in the media, highlighting how authentic storytelling raises awareness, reduces stigma, and celebrates resilience ❤️ Most importantly, we listened, learned, and celebrated the voices and stories that continue to guide and inspire us. Thank you to the Sickle Cell Disease Association of America, Inc. — National (SCDAA), Regina Hartfield, SCDAA President and CEO, and her team for another inspiring, educational, and empowering event. We left energized and are already looking forward to next year. #SickleCellAwareness #SCDAAEmpowered

🎙️ Cheat Codes Podcast Episode Alert! 🎙️ In this episode, hosts Dr. Z (Ahmar U. Zaidi, MD) and Dr. C (Michael Callaghan) talk with TaLana Hughes and Cassandra Trimnell to explore what “the #SickleCell community” truly means. They talk about how patients, caregivers, providers, and allies overlap and come together to create spaces of hope, support, and change. From sharing information to finding your “tribe,” this conversation highlights how connection fuels progress in #SickleCellDisease – whether online, in person, local, or global. Listen to the episode here: http://bit.ly/4gEuMdD This podcast is not intended as medical advice. Please consult your healthcare team with any treatment-related questions. #SickleCellAwareness #SCDAA2025 #SCDAAEmpowered

#AgiosNews: The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency has adopted a positive opinion for the new indication for our first-in-class pyruvate kinase (PK) activator for the treatment of anemia in adult patients with #thalassemia. The final decision from the European Commission is expected by early 2026. Read our press release for more information: http://bit.ly/42MZtb3

We will be hosting a conference call and live webcast on Thursday, October 30, at 8:00 a.m. ET to report and discuss our third quarter 2025 financial results and other business highlights. A live webcast can be accessed under “Events & Presentations” in the “Investors” section of our website. The webcast will be archived and available for replay two hours after the event. Read more: http://bit.ly/4qewS8A

As we close out #HispanicHeritageMonth, we’re proud to spotlight Marvilla Asencio Moreira, PharmD, RPh, a Manager on our Clinical Supply Chain team and an active member of our LatinX Employee Resource Group (ERG). Born and raised in Puerto Rico, Marvilla shares how important it is to celebrate her roots and heritage – and how the LatinX ERG provides space for connection and community. Over the past two years, Marvilla has brought her culture to life by organizing salsa dance lessons led by an instructor and sharing classic Puerto Rican dishes and artwork. These activities created meaningful opportunities for colleagues to learn, connect, and celebrate together. We are grateful to Marvilla and all our ERG members who help foster belonging, openness, and cultural appreciation across our company. #InclusionMatters 

We were thrilled to host students from Princeton University’s Biotech Group at our Cambridge headquarters for an interactive panel and networking event. Our Chief Medical Officer and Head of R&D, Sarah Gheuens, was joined by Audra Boscoe, Kelly Kemp, Abdulafeez (Deji) Oluyadi and Michael McVay to share perspectives on career paths, day-to-day work, and the many ways biotech professionals contribute to advancing science. During the discussion, we emphasized that progress in biotech depends not only on scientific breakthroughs but also on the people behind them – those willing to share knowledge, learn from different perspectives, and build bridges across disciplines. Careers in biotech can take many shapes and turns, but the constant is advancing science that changes lives, the very impact we’re all striving to achieve. #BiotechCareers #STEM #STEMCareers 

This week, our team came together for our annual Fall Gathering – a special time to reconnect, recognize our achievements, and reflect on the “why” behind the work we do. As part of this tradition, we proudly joined the Cooley's Anemia Foundation’s Anemia Foundation Annual Care Walk, standing alongside the community to raise awareness and support for people living with #Thalassemia and their loved ones. We’re grateful to have walked together in support of this important cause, reminding us that the impact of our work extends far beyond the lab and office walls. 📸 Check out some of our favorite highlights from the day! #CAFCareWalk25 #ThalassemiaAwareness 

🎙️ Thal Pals Episode Alert! 🎙️ In this episode, our host and patient advocate NinaMaria Badalamenti sits down with Dr. Arielle Langer, hematologist at Brigham and Women's Hospital, to explore fertility, pregnancy, and family planning for people living with #Thalassemia. From timing and iron management to genetic counseling, birth control options, and postpartum care, this conversation offers clear, practical guidance to help patients and families navigate every stage of the journey. Listen to the episode here: http://bit.ly/3ILkThL This podcast is not intended as medical advice. Please consult your healthcare team with any treatment-related questions. #ThalassemiaAwareness #Hematology

Applications are now open for the 2026 – 2028 Fellowship Program! In collaboration with Massachusetts College of Pharmacy and Health Sciences (MCPHS), this program gives Doctor of Pharmacy (PharmD) graduates the opportunity to train in the biopharmaceutical industry. Fellows gain hands-on experience, one-on-one mentorship, and the tools to accelerate their careers while making a meaningful impact on patients’ lives. For this cycle, we’re recruiting in Medical Affairs, Medical Safety and Risk Management, and Clinical Development (Clinical Science). Learn more here: http://bit.ly/46Or7pb Apply here: http://bit.ly/482EKn1 #MCPHSFellowship #PharmDtoIndustry #PharmacyCareers