General Catalyst

“You have to get used to the idea that you will have this potent force that lives alongside us.” -Hemant Taneja We're entering a world where AI will be a second species: an intelligent, complementary presence that works alongside us. Some AI will manage humans, some humans will manage AI, and we’ll need to establish new norms for this symbiotic relationship. At the Forbes 30 Under 30 Summit, our CEO Hemant Taneja sat down with Steven Bertoni to explore what it takes to build for abundance in an AI era. Full conversation in the comments. #Forbes30U30

4.6 years. That's how long patients wait for an autoimmune diagnosis, cycling through five physicians, only to enter a system designed for symptom management rather than addressing root causes. Over 50 million Americans, predominantly women, live with these conditions that consume nearly 30% of pharmacy spend for self-insured employers. We're leading WellTheory's $14M Series A to change that with an enterprise platform combining registered dietitians, health coaches, and applied AI to address root causes like nutrition, stress, sleep, and lifestyle. CEO Ellen Rudolph built this from lived experience and has surpassed our expectations from an execution standpoint. The economics are striking: $5,200 average annual savings per patient, 71% reduction in imaging services, 64% fewer ER visits, 15% lower biologics utilization. This is health assurance at work: moving from reactive treatment to proactive, preventive care that bends the cost curve while improving lives. Welcome to the GC Famiglia! Explore why we invested by Holly, Candace, and Tyler in the comments. Sources: Autoimmune Association, Med City News, Accorded

AI is rapidly penetrating every part of our personal and work lives, but today’s solutions are largely isolated into chat environments and away from where users actually get work done. That's why we're leading the seed round for Strawberry, a browser with built-in AI assistants that work alongside you on any website. Strawberry turns browsers into automated assistants that can research, click, type, and summarize, bringing AI directly to people. Founder Charles Maddock started coding at age 10 and co-founded a game development studio in his teens. He combines a deep urge to create with remarkable product intuition and a powerful ability to inspire and attract top-tier talent. Alongside co-founders Sebastian Thunman and Arian Hanifi, he's building the product that can make AI both accessible and practical for knowledge workers' everyday tasks. Welcome to the GC Famiglia! Explore our conversation with Charles and see how we're Seeding the Future with Yuri, Jeannette, Zeynep, and Cecilia in the comments.

Insurance is a €7 trillion market where half of brokers' time disappears into administrative work. When we met Fabian Wesemann and Sergi Baños Lara, we knew we found the right team. They bring deep industry expertise, entrepreneurial grit, and a clear vision for what comes next. Afori turns unstructured communications into structured workflows, letting brokers reclaim an hour per day for advising clients and driving growth. That's why we're leading the seed round for Afori, an AI platform automating insurance brokers’ back-office operations. Welcome to the GC Famiglia! Explore our conversation with Fabian and Sergi and see how we're Seeding the Future with Jeannette, Zeynep, and Samuel in the comments. Sources: Allianz and Afori

Institutional crypto adoption is accelerating, but compliance infrastructure hasn't kept up. Legacy tools can't handle blockchain's speed and complexity. That's why we're co-leading CipherOwl's seed round to build the future of intelligent compliance infrastructure for digital assets. Founders Leo Liang and Ming Jiang bring deep technical expertise from scaling data infrastructure at Coinbase, where they saw firsthand the compliance gaps institutions face with blockchain. CipherOwl's Know-Your-Transaction API delivers what enterprises and regulators need: clear, real-time risk intelligence with full auditability. Their platform integrates seamlessly into existing workflows, letting institutions engage confidently with decentralized networks. Welcome to the GC Famiglia! Explore our conversation with Leo and Ming and see how we're Seeding the Future with Marc Bhargava in the comments.

Vulcan Technologies is building an operating system for the global regulatory compliance market, serving both government and enterprise. That’s why we’re leading their seed round. Founders Tanner Jones, Aleksander Mekhanik, and Chris Minge are developing legal cartography software that reads every law across the U.S., spots conflicts, and helps agencies write new regulations in an efficient way They're already saving the State of Virginia 90 percent on implementation costs (Source: Vulcan Technologies). “Navigating today’s regulatory landscape is costly and complex. Vulcan is building technology to help address these challenges. They’ve assembled a strong team of AI, engineering, and legal experts, and we’re excited by their early traction with government partners. We look forward to supporting their growth as they expand beyond the public sector.” -GC’s Yuri Sagalov Welcome to the GC Famiglia! Explore our conversation with Tanner, Aleksandr, and Chris, and see how we're Seeding the Future by Yuri and Sho Sho in the comments. #AppliedAI

With 27 million online shoppers, India has the second-largest digital customer base in the world, yet there's a massive supply gap for the clean, sustainable brands these consumers are seeking (Source: Bain). That's why we're leading Meolaa's seed round as they build a portfolio of purpose-driven, digital-first microbrands for India's rapidly evolving consumer landscape. At General Catalyst, we back founders who see market gaps as opportunities to build the brands and experiences that consumers truly want. This is precisely the case with founder Ishita Sawant. She brings years of global brand growth experience and shares an unwillingness to accept that India's consumers seeking sustainable products should be underserved by existing supply chains. "What excites us about Meolaa is Ishita's vision to build an AI-native FMCG powerhouse, replacing traditional R&D with intelligent systems that compress brand development from years to months. Her consumer-first approach and global brand insights, combined with her bias for action, position her uniquely to identify whitespace opportunities and execute rapidly. Under Ishita's leadership, they're reimagining how consumer brands are built and scaled for the modern economy." -GC’s Neeraj Arora Welcome to the GC Famiglia! Explore our conversation with Ishita and see how we're Seeding the Future by Neeraj and Siddhi in the comments.

The U.S. spends twice as much on healthcare as other countries, with often worse outcomes (Source: Peter J. Peterson Foundation). Fixing America's healthcare industry requires ecosystem transformation. Enter HATCo, our Health Assurance Transformation Company reimagining health systems where healthcare is proactive, affordable, and accessible for all. Our approach combines expertise, technology, and collaboration to build resilient health organizations and address workforce challenges. We acquired Summa Health, one of Ohio’s largest integrated systems, as a wholly-owned subsidiary of HATCo to create a new, more equitable system of community-based, lifelong healthcare. We think this investment will drive immediate and sustainable value to the organization and the patients it serves. It is designed to serve as a blueprint for broader healthcare transformation in the U.S. and beyond. We work with our network of more than 23 health system partners, representing about 15% of U.S. healthcare revenue, to share best practices and scale impact. We provide strategic advisory services to help health systems adopt value-based care and digital health solutions. HATCo is a generational investment in healthier communities, driven by better outcomes and focused on sustainable transformation. Together with our partners, we're creating a new model for healthcare abundance. Thank you to Cliff Deveny MD, George Strickler, Benjamin Sutton, Daryl Tol, Hemant Taneja, Marc Harrison, Kate Walsh, Reva Nohria, Sing Yuen (Joey) Chan, Josette Beran, Molly Blaauw Gillis, Christopher McCain, Gabriella Giglio, and Paul Fielding for their visionary leadership to build the future of healthcare. Explore the latest edition of Proof Points to discover what HATCo delivers. #Transformation #HealthAssurance

A few of September's milestones: On famiglia… 🔹 I published my latest book, The Transformation Principles, co-authored with Kevin Maney, outlining nine principles from my 20+ years of building and investing. We kicked off the book launch by convening members of our New York Famiglia across tech, finance, media, and policy to have a discussion with Fareed on how a principle-led approach can help us tackle questions around geopolitical ambiguity, workforce transformation, etc. More here: https://lnkd.in/ge96kK2D 🔹General Catalyst and Transfyr hosted the American Dream for Science Summit in DC, convening leaders across Pharma, Government and Academia, to craft strategies to reignite America’s edge in medical and scientific discovery 🔹We welcomed 12 new team members across GC On building companies… 🔹We partnered with 12 seed and early stage companies, including The Interaction Company of California, Nolla Health, Standard Kernel Co., Spiral, Geordie AI, encentive GmbH, PRYPCO. Welcome to the Famiglia! 🔹We doubled-down on 9 of our existing investments, including with Anthropic, Mistral AI, Aven, Judi Health (fka CapitalRx), and Birches Health, continuing to support these companies as they build for long-term endurance 🔹Our Customer Value Fund led Quo’s $105M investment to boost their go-to-market engine, helping small businesses transform customer connection by bringing calls, texts, and customer data together 🔹Rox launched their AI sales platform, a step towards business transformation with AI in the sales function, with revenue agents that handle account research, prioritization, and outreach 🔹Helsing unveiled CA-1 Europa, an autonomous fighter jet designed and built in Europe, demonstrating Europe’s sovereign capabilities at the frontier of autonomy and AI 🔹Pacific Fusion announced plans for a $1B research and manufacturing facility in Albuquerque, NM, a step forward in building the foundation for commercial fusion 🔹Five of our companies were named to Fortune’s Future 50 list (Anthropic, Commure, Canva, Discord, Samsara)  🔹22 of our companies were recognized on TIME’s World’s Top HealthTech Companies of 2025 list. Congrats to the teams at Aidoc, Augmedix, Cadence, Cityblock, Commure, Equip, Fabric, Maven, Memora, Neko, Osmind, Plume, Sesame, Soda Health, SonderMind, Spring Health, Story Health, Sword Health, Teladoc (Livongo), Tendo, Transcarent, Well On transforming industries... 🔹We announced that WellSpan Health, the 220+ site integrated health system based in PA, will be HATCo's first Transformation Partner, signing a Transformation as a Service (TaaS) agreement where HATCo will deploy a team to WellSpan to co-develop their tech stack 🔹The General Catalyst Institute celebrated one year of helping founders and policymakers collaborate to build global resilience across defense, healthcare, fintech, and beyond Onwards to October