Midwest AViDD Center reposted this
New paper from our work as part of the Midwest AViDD Center. Congrats to the team! Mackenzie Wyllie Rayhan Gafur Biswas, Ph.D. UMN Department of Medicinal Chemistry
Our mission at the Midwest Antiviral Drug Discovery (AViDD) Center is to quickly develop the next generation of antiviral drugs for pandemic-level viruses, including SARS-CoV-2, Ebola, Lassa and Zika viruses. The Center is part of a network of nine national centers established by the National Institute of Allergy and Infectious Diseases (NIAID). The Center is a key part of an overall initiative to bring expertise across disciplines to discover effective responses to pandemics, life-threatening infections, and antimicrobial resistance through basic, translational and clinical research. Embedded in an academic setting, we utilize a balance of innovative and proven approaches and technologies to develop inhibitors to established druggable processes and less conventional but equally essential viral processes. We aim to deliver novel inhibitors that can be developed into effective orally available drugs that potently and safely suppress virus replication and help prevent infections and adverse clinical outcomes including death.
External link for Midwest AViDD Center
321 Church St SE
Minneapolis, Minnesota 55455, US
Midwest AViDD Center reposted this
New paper from our work as part of the Midwest AViDD Center. Congrats to the team! Mackenzie Wyllie Rayhan Gafur Biswas, Ph.D. UMN Department of Medicinal Chemistry
Full SLAS Discovery Special Issue Available Now: Outcomes from Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern https://lnkd.in/gQYq3K-C #antiviral #drugdiscovery #pandemic #structuralbiology #zika #ebola #covid19 #lassa
Midwest AViDD Center reposted this
The Department of Medicinal Chemistry is proud to share that our very own Dr. Daniel Harki has been named a Fellow of the Royal Society of Chemistry. Congratulations are in order! 🎉 😊 👏 👍 Read more:
A new study by the Midwest AViDD Center reveals that Sudan ebolavirus glycoprotein binds to the human NPC1 receptor approximately 9 times more strongly than Ebola virus glycoprotein. #Ebola #sudan #filovirus University of Minnesota Medical School https://lnkd.in/g9Wtf6XT
Ebola virus, one of the deadliest pathogens, has a fatality rate of about 50%, posing a serious threat to global health and safety. To address this challenge, researchers at the University of Minnesota and the Midwest Antiviral Drug Discovery (AViDD) Center have developed the first nanobody-based inhibitors targeting the Ebola virus. #nanobody #ebola #marburg #AViDD University of Minnesota Medical School https://lnkd.in/gcJcXf7j
Researchers at the University of Minnesota and the Midwest Antiviral Drug Discovery (AViDD) Center introduced Nanosota-9, a nanobody capable of neutralizing a broad range of SARS-CoV-2 variants. #nanobody #AViDD #antiviral #drugdiscovery University of Minnesota Medical School https://lnkd.in/gBKrfu86