You won't want to miss this edition of the Nested Knowledge Newsletter. Jam packed with all things ISPOR 2025, our new feature launch, and a plethora of new partnership announcements. Check it all out and more with Living Data 7.0! #ISPOR205 #HEOR #HTA #SLR #Healthtech #metaanalysis
Nested Knowledge, Inc.
Software Development
Saint Paul, Minnesota 2,666 followers
Modernizing clinical evidence synthesis. See it in action: https://nested-knowledge.com/
About us
Nested Knowledge® offers a comprehensive software platform for AI-assisted systematic literature review and meta-analysis. The software is composed of two parts which work in tandem: Search, screen, extract data, and complete critical appraisal with AutoLit®. Visualize, analyze, publish and share insights with Synthesis. For each step along the way, use our AI tools to accelerate your research, query the literature, draft systematic literature reviews or diverse review types, and create 'living', updatable Synthesis of evidence on your key medical research questions!
- Website
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https://about.nested-knowledge.com/
External link for Nested Knowledge, Inc.
- Industry
- Software Development
- Company size
- 11-50 employees
- Headquarters
- Saint Paul, Minnesota
- Type
- Privately Held
- Founded
- 2018
- Specialties
- Meta-Analytical Review, Clinical Outcome Data, Systematic Review, HEOR, EUMDR compliance, Medical Writing, Manuscripts, Software, Evidence Synthesis, Scoping, Medical Research, FDA regulatory compliance, Medical Device, and Literature Review
Products
Locations
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Primary
Saint Paul, Minnesota 55117, US
Employees at Nested Knowledge, Inc.
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Julia Brodsky Ph.D.
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Anthony Coniglio, PharmD
President OPUS Pharma Consulting
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Asli Gurler Aras, Ph.D.
Strategic Leadership | Corporate Development | Growth Planning and Execution | Business Strategy | Life Sciences | BioTech | Health Data
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Dr Neeraj Mehta
AI Tools and Solutions for Publishing and Life Sciences. Entrepreneur, Consultant & Advisor to Global Companies. PUBLISHING, CONSULTING, STRATEGY…
Updates
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Ranita Tarchand crushing it for Nested Knowledge at #ISPOR2025!
Global Market Access & Policy Leader | HTA Strategy | Equity in Innovation | I help scale patient access by aligning policy, evidence & value
Forum Recap: Our #ISPOR2025 forum, “Leveraging Automated Tools for Literature Reviews in HEOR: Opportunities, Challenges, and Best Practices,” brought together an engaged audience and sparked rich discussion around the future of evidence synthesis in #HTA and #HEOR. We explored how #AI and #automation can support screening, data extraction, and synthesis , while emphasizing the importance of human oversight, transparency, and scientific rigor. Highlights included: Real-world case study from the Health Equity SIG Scoping Review Discussion on methodological integration, reproducibility, and trust Forward-looking perspectives on broader adoption across HEOR and regulatory settings A huge thank you to our amazing panelists: Ranita Tarchand (Nested Knowledge, Inc.) Rajshree Pandey (ISPOR HER SIG) Mitch Higashi (ISPOR—The Professional Society for Health Economics and Outcomes Research) The thoughtful questions and engagement from the audience made this session especially rewarding. Keep an eye out for upcoming #ISPOREurope sessions about this topic #HTA #HealthEquity #EvidenceSynthesis
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Nested Knowledge, Inc. reposted this
#HumanInTheLoop was certainly my byword at #ISPOR2025, and I think it's the best and only final defense against AI hallucinations. Great points here and align with the philosophies of Nested Knowledge, Inc.!
🎉 Reflecting on an Incredible #ISPOR2025 in Montreal! Our team had an amazing time at ISPOR 2025—reconnecting with clients and showcasing CLINIGMA's latest in-trial interview solutions. After working diligently for so long to advance our interview solutions, it was incredibly rewarding to finally present these solutions to our clients. 🔍 Key Insights from #ISPOR2025: 📌 AI in HEOR/RWD was a major theme. Speakers shared advancements in AI spanning across literature reviews and rare disease research. Key takeaways include "human-in-the-loop," a reference to humans partnering in these AI advancements to reduce associated limitations (Kevin Kallmes of Nested Knowledge, Inc.) like hallucinations. Hallucinations—false or misleading information presented as fact— and can erode trust in the data (Lisa Pilgram from Children's Hospital of Eastern Ontario Research Institute). 📌 Excellent seminars at #ISPOR2025 focused on patient voice and the value of qualitative data in rare diseases. Asia Sikora Kessler (Ionis Pharmaceuticals, Inc.) drew strong audience engagement on Day 2 with her presentation about conducting in-trial interviews. Additionally, Kate Williams PhD´s session on how in-trial interviews can inform HTA decision-making was particularly insightful. Very relevant to their presentations, we presented right after a poster from our collaborations with Sanofi: "Facilitating Effective Implementation of Qualitative in-Trial Interviews"—summarizing the important steps needed to ensure a successful execution of in-trial interviews seen from a large global pharma perspective. A huge thank you to everyone who visited our booth, shared insights, or connected with us. The conversations and collaborations at #ISPOR2025 will drive meaningful progress in our capturing of patients voices in relation to clinical trials. What was your biggest takeaway from ISPOR? Until next time! 🚀 #HEOR #HealthcareInnovation #RealWorldEvidence #AIinHealthcare #PatientCentricity #ISPOR
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One for the books!
"It's not a retreat, it's a tactical maneuver" - Keith Kallmes while hosting the first ever Nested Knowledge, Inc. company retreat! From cold plunges to rainstorms in the Green mountains to improv lessons, this has been just about as chaotic and uphill as starting a company. Thanks team for an amazing conference, trip, and ((tactical maneuver))!
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Don't forget about our amazing new feature launch: Smart MA Extraction! Try it for yourself today!
Smart MA Extraction is here! Check out this brief demo, or head over to Nested Knowledge and try it for yourself. If you are new to Nested Knowledge and would like a demonstration of this or any of our other features, sign up for a demo: https://lnkd.in/gPHGC-bh Are you headed to #ISPOR2025? We'll be at booth 1620. Grab a timeslot below: https://lnkd.in/gPHGC-bh
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From everyone at Nested Knowledge, it was a sincere honor and thrill to be able to connect, learn, and grow together with all of you at #ISPOR2025 in Montreal. This was a wonderful event that will invigorate us to keep building and to keep pushing to bring you the best experience we possibly can at Nested Knowledge! #heor #slr #jca #hta #metaanalysis #healthtech #ISPOR2025 #nestedknowledge
Join us for #ISPOR2025 in beautiful Montreal for a first look at automatic quantitative data extraction powered by AI. Building on the success of Core and Adaptive Smart Tags, which have truly revolutionized qualitative data extraction, we are excited to bring the same speed, accuracy, power to data elements and interventions in your Nested Knowledge workflow. This feature has been a long time coming: it's not just about intra-study data extraction; it's inter-study harmonization, and like core smart tags, this feature will build a preliminary tagging ontology for you as well. Stop by our booth (1620) to experience it first hand. Let us know you are interested and we'll make sure you have a time slot: https://lnkd.in/gPHGC-bh #marketaccess #AI #SLR #HTA #pharma #valueaccess #medicaldevice
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Nested Knowledge, Inc. reposted this
Kevin Kallmes, Keith Kallmes, and the incredible team at Nested Knowledge, Inc., - we at Cytel are excited to collaborate and drive innovation that puts synthesized evidence directly into the hands of healthcare decision-makers, ultimately advancing better health outcomes. Please reach out if you want to learn more about our collaboration.
What an event! We just left the rooftop of the Hotel Montville, where Cytel put on an exciting and relaxing evening with a beautiful sunset skyline. Wyatt Gotbetter, Nathalie Horowicz-Mehler, PhD and the whole Cytel team are true leaders in the field and we are confident our partnership will bring truly unique capabilities to #HEOR research. Thank you for the hospitality and a great future ahead!
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Nested Knowledge, Inc. reposted this
If you're interested in learning more about the powerful tools from Nested Knowledge and the impact it can have on your team and business, I'd love to speak with you and discuss how we can optimize your evidence generation and management workstreams.
Last year, we announced a strategic partnership with Envision Pharma Group. Since then, we've been hard at work, integrating Nested Knowledge with iEnvision to seamlessly offer the benefits of both platforms. For the first time, you can now unlock the power of Nested Knowledge and iEnvision for unprecedented insight into the flow of evidence across the product life cycle. Then, pair technology with human expertise from Envision Pharma Group. Check it out: https://lnkd.in/gahqkPTe Interested to learn more? Stop by our booth (1620) at #ISPOR2025 #marketaccess #medicalaffairs #evidencesynthes #ai
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Nested Knowledge, Inc. reposted this
What an event! We just left the rooftop of the Hotel Montville, where Cytel put on an exciting and relaxing evening with a beautiful sunset skyline. Wyatt Gotbetter, Nathalie Horowicz-Mehler, PhD and the whole Cytel team are true leaders in the field and we are confident our partnership will bring truly unique capabilities to #HEOR research. Thank you for the hospitality and a great future ahead!
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Nested Knowledge, Inc. reposted this
My first podium presentation ever at #ISPOR2025! I am not usually one for nerves, but my co-presenters were amazing and difficult to follow... Luckily, the software and data validating our Smart Search speak for themselves! Even as we launch new tools for #AI, our real buzzword is human-in-the-loop, And I feel great appreciation for medical librarians everywhere with this launch! Thanks to everyone who came and asked great questions, and see you tonight and tomorrow for a great conference! Grace Fox Nested Knowledge, Inc. Karl Holub
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