Primrose Bio

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Primrose Bio will be presenting and exhibiting at PepTalk: The Protein Science and Production Week 2026 in San Diego, CA (January 19–22, 2026). Powered by Pseudomonas fluorescens, Pfenex Expression Technology® is our scalable microbial expression platform designed for high-yield protein production with rapid, data-driven development cycles. It helps teams move from construct to correctly folded protein, with expression and secretion strategies that support protein quality, productivity, and manufacturability. This year, we are highlighting Pfast™, the Pfenex feasibility program designed to deliver rapid, cost-effective insight into platform fit before committing to full-scale process development. At PepTalk: • Diane Retallack will present a talk on Pfast for accelerating antibody screening • Jasmina Racic - Radoicic, PhD and Yinghui Lee, PhD will be showcasing scientific posters • Alec Tzianabos will be at the Primrose Bio exhibit booth throughout the week If you’ll be attending and would like to connect, stop by the booth or email partnering@primrosebio.com #ProtienExpression #PfenexExpressionTechnology #PrimroseBio #CHIPepTalk Cambridge Healthtech Institute

Primrose Bio will be attending JPM Week 2026 in San Francisco, January 12–15. Our team is looking forward to conversations and new connections focused on protein and mRNA manufacturing solutions that help move promising biotherapeutics and vaccines forward. If you’ll be attending, we’d be glad to meet. Please schedule time through the BIO Partnering app with Andrew Burch, Diane Retallack, Simon Latimer, or Louis J. Cantolupo. Looking forward to seeing you in San Francisco. #JPMWeek #Biotherapeutics #vaccines #Partnering #PrimroseBio

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We’re pleased to share an opinion piece published today in The San Diego Union-Tribune by Primrose Bio’s Andrew Burch and Helge Zieler, PhD, contributing to the public conversation on mRNA and its role in modern medicine. Drawing on decades of scientific research, the piece explains why continued innovation in mRNA biotherapeutics and vaccines remains essential for public health, scientific leadership, and long-term global competitiveness. Read the full essay, “mRNA medicines are the future of modern health — not a threat,” here: https://lnkd.in/gMD-c-hY #mRNA

Primrose Bio is heading to Antibody Engineering & Therapeutics in San Diego, December 14-17, 2025. • Diane Retallack, PhD is presenting a talk on our rapid, robust solution for accelerating antibody screening • Chris Warner, PhD is presenting a scientific poster on overcoming ncAA production bottlenecks for high-titer antibody expression • We are exhibiting at Booth 305 – connect with Andrew Burch, Louis J. Cantolupo, and Alec Tzianabos Stop by our booth to discover our Pfenex Expression Technology platform for improved protein expression, including unmatched production of antibody fragments. #AntibodyEngineering #PrimroseBio #PfenexExpressionTechnology #ProteinExpression

What an inspiring week in Berlin at the 13th International mRNA Health Conference, where the full mRNA ecosystem came together to share the latest breakthroughs shaping the future of RNA-based medicine. The momentum behind mRNA innovation continues to grow! We were proud to introduce Prima RNApols™ ExTend Cap AU and to contribute through presentations from Helge Zieler, PhD, and Sabrina Baffert, MPH, along with conversations at our booth. #PrimroseBio #mRNAHealthConference #mRNA #PrimaRNApols mRNA Conference

Primrose introduces today Prima RNApols™ ExTend Cap AU, an RNA polymerase engineered to significantly improve manufacturing of self-amplifying mRNA vaccines and therapeutics. It enables high-yield, fully capped self-amplifying mRNA with less capping reagent, template DNA and RNA polymerase. Read more here: https://lnkd.in/gB6E7wXH #PrimaRNApols #PrimroseBio #mRNA

We're looking forward to connecting with the global mRNA community at the 13th International mRNA Health Conference in Berlin, November 11th-13th. Primrose will introduce Prima RNApols™ ExTend Cap AU, enabling higher quality, more cost-effective mRNA. The team will also share insights on the future of mRNA manufacturing. • Presentation: Helge Zieler, Chief Technology Officer • Scientific Poster: Sabrina Baffert, MPH, Director, Molecular Biology • Exhibit: Booth #10 • Team also in attendance: Chief Executive Officer Andrew Burch; Chief Business Officer Michele Rubino; Associate Director, Product & Business Development Jennifer Wittbold; and Advisor Khaled Yamout. Stop by Booth #10 or connect with us ahead of the event. #PrimroseBio #mRNAHealthConference #mRNA #PrimaRNApols mRNA Conference

Primrose Bio is launching Prima RNApols™ ExTend Cap AU next month. This enzyme enables high-quality, cost-efficient manufacturing of fully capped self‑amplifying mRNA. Highlights include: - High capping efficiency at 1.5 mM AU cap, lowering reagent use  - Ultra-low dsRNA to ease purification and improve safety and performance  - High‑yield saRNA with preserved integrity compared to T7 Sign up to be notified of the launch: https://lnkd.in/g-2sXQqz #PrimaRNApols #PrimroseBio #mRNA