Medicinal Chemistry is a dynamic, multifaceted scientific discipline that is dedicated to the improvement of human health through research leading to new concepts for the design and development of safe and effective therapeutic, diagnostic, and environmental agents. Research in Medicinal Chemistry involves the application of both chemical and biological principles to investigations between molecular structure and biological activity. Examples include the design and synthesis of new medicinal agents, the development of new concepts for the design of selectively acting ligands, improvement of existing drugs by molecular modification, structure elucidation of biologically active natural products, physicochemical and theoretical studies on drugs and macromolecules, investigations of the effects of molecular structure on the distribution, pharmacokinetics, metabolism and toxicity of biologically active substances, and the application of the basic principles of chemistry and molecular biology to the development and production of medicinals from natural sources.
External link for UMN Department of Medicinal Chemistry
308 Harvard St SE
8-101 Weaver Densford Hall
Minneapolis, Minnesota 55455, US
Check out this new publication from Dr. Daniel Harki and his team, as well as folks from the Midwest AViDD Center! 👏 👍
New paper from our work as part of the Midwest AViDD Center. Congrats to the team! Mackenzie Wyllie Rayhan Gafur Biswas, Ph.D. UMN Department of Medicinal Chemistry
Congratulations to first-year PhD student Chloe Cox, who was awarded a competitive 3M Science and Technology Graduate Fellowship. The multi-year fellowship provides support to exceptional incoming PhD students in science and engineering. Way to go! 👏 😊 👍 You can read more here: https://lnkd.in/gVFeP5mw
Please join us tomorrow as we welcome Dr. Thomas Maimone from the University of California, Berkeley to campus to present a lecture to the UMN community as part of our seminar series: "Synthetic Studies and Applications of Complex Natural Products" We are looking forward to this - more details are below 👇
We are so excited to welcome Dr. Peter Wipf from the University of Pittsburgh to campus tomorrow to present a Distinguished Lecture as part of our seminar series! 🎉 His talk is entitled: "sp3-Rich Bioisosteres in the Development of Prostate Cancer Therapeutics" This is going to be an excellent talk - please join us! Details are below 👇
Way to go Erik Moran, Dr. Natalia Tretyakova, and the Tretyakova Lab! 👏 🎉
Happy to share that my work on 1,3-butadiene adducts has been published in Toxics. Check it out: https://lnkd.in/gNq-CMfr
Big news on the renewal of the Chemistry-Biology Interface Training Grant! 👇 🎉 👏
The Chemistry-Biology Interface Training Grant isn’t just one of the longest-running student training grants at the University of Minnesota – it’s one of the longest-running training grants in the nation. With the help of a recent grant renewal from the National Institutes of Health, the program will continue to push the boundaries of discovery and train scientists at the cutting edge of chemical biology. Explore the program's story here: https://lnkd.in/g5JiC7j8 🧬 🧪
UMN Department of Medicinal Chemistry reposted this
Had a fantastic visit to Búzios, Brazil for BrazMedChem 2025. I really enjoyed getting to know folks from the Brazilian med chem community and building connections with the ACS Division of Medicinal Chemistry. Thanks also for the invitation to present research from my group! I look forward to returning for a future meeting!
Mark your calendars and check out the details on EFMC-ACSMEDI Medicinal Chemistry Frontiers 2026! It will be held from June 22-25, 2026, in Dublin, Ireland 👇
We are excited to announce that the EFMC-ACSMEDI Medicinal Chemistry Frontiers 2026 will take place in Dublin, Ireland, June 22–25, 2026! 👉 Co-organised by EFMC (European Federation for Medicinal chemistry and Chemical biology) and ACS MEDI (Division of Medicinal Chemistry of the American Chemical Society), the event will be chaired by Prof. Marina Rubini (University College Dublin, Ireland). 💡 The programme will feature: 3 inspiring plenary lectures 9 sessions on hot topics in Medicinal Chemistry: • Targeted Protein Degradation and Induced Proximity • New Insights into Anti-infective Agents • Late-stage Functionalization in Medicinal Chemistry • Early Career • Chemical Biology and Emerging Modalities • Carbohydrates in Health and Disease • Exploring Epigenetic and Epitranscriptomic Pathways for Precision Medicine • ML based drug discovery – Real-life Experiences in Medicinal Chemistry • New Frontiers in Neuroscience and Immunology 🔬 Plus ~18 oral communications selected from abstracts, a poster session, a commercial exhibition, and an extensive social programme. 📅 Registration and abstract submission will open by the end of October 2025 on www.medchemfrontiers.org We look forward to welcoming you in Dublin! 🇮🇪 #EFMC #ACSMEDI #MedicinalChemistry #DrugDiscovery #Conference2026
Congratulations to the following Medicinal Chemistry faculty, who were awarded College of Pharmacy Special Merit Awards: Dr. Gunda Georg Dr. Carrie Haskell-Luevano Dr. David Ferguson Dr. Elizabeth Ambrose Dr. Daniel Harki 👏 👏 Read more here: https://lnkd.in/g3eTvps8
This week, our very own Mark C Kelley from Dr. Daniel Harki's lab will be presenting on some interesting research for our seminar series! Join us tomorrow at 3:35pm CST in Moos Tower for some cool science. More details are below 👇