Vizgen

New in Nature Biotechnology: MERFISH 2.0™ and other advances in spatial transcriptomics are transforming our understanding of disease mechanisms. At Vizgen, we're proud to contribute to this progress with our new MERFISH 2.0 chemistry, which offers enhanced sensitivity and reproducibility, even in challenging samples like FFPE tissues. By enabling high-resolution, single-cell spatial transcriptomics, researchers are delving deeper into tissue biology, revealing complex patterns of gene expression and cellular interactions. Explore how advancements like MERFISH 2.0 are shaping the future of spatial biology: https://hubs.ly/Q03nV4sr0 #SpatialTranscriptomics #SpatialBiology

Wrapping up an incredible week in Sydney🇦🇺 with the 2nd MERSCOPE User Group Meeting, followed by Oz Single Cell! It was inspiring to connect with our customers and hear about the amazing science! A big thank you to our co-marketing partners, Scale Biosciences and BioTuring and to our distribution partner, Integrated Sciences, for their support. We’re excited to keep the momentum going—see you soon in Melbourne for the WEHI (Walter and Eliza Hall Institute of Medical Research) Spatial Symposium! #OzSingleCell #MERFISH2_0 #MERSCOPEUltra

There's still time to register! ⏲️ Join us and Global Engage next Wednesday, May 28, as we explore how Vizgen’s new MERFISH 2.0™ chemistry and the MERSCOPE Ultra™ Platform are advancing spatial genomics—unlocking new possibilities for FFPE and archived tissue samples. Alex Genshaft, Product Manager for Reagents & Consumables at Vizgen, will introduce MERFISH 2.0 chemistry and showcase its optimized workflow for robust transcript detection in FFPE tissues. Mark Watson, M.D., Ph.D., Margaret Gladys Smith Professor at Washington University School of Medicine in St. Louis, will present breast cancer datasets generated with MERFISH 2.0 and discuss how spatial genomics is driving new insights into triple-negative breast cancer to aid discovery of novel prognostic biomarkers. Don’t miss this opportunity to see how cutting-edge spatial transcriptomics is transforming both basic and translational research. 📆Date: Wednesday, May 28 🕙Time: 11 am ET | 4 pm BST | 11 pm SST ✏️Register here: https://hubs.ly/Q03ns0PD0 #SpatialBiology #MERFISH

🎉 We successfully wrapped up the 2nd MERSCOPE User Group Meeting (UGM) in Australia yesterday! Held at UNSW, Sydney in collaboration with Iveta Slapetova from the Katharina Gaus Light Microscopy Facility (KGLMF), the event was packed with insightful talks and vibrant discussions. 🔬 A huge highlight was the incredible presentation by Dr. Gavan McNally, alongside exciting updates on MERFISH 2.0™ and MERSCOPE Ultra™ presented by Paul Rasmussen, complete with compelling case studies. 🧪 Thaddaeus Teo shared practical guidance on histology, sample prep, and data analysis for MERFISH 2.0, sparking engaging conversations throughout the afternoon. 🙌 We’re also grateful to our co-marketing partners Scale Biosciences and BioTuring for enriching the program with their talks on single-cell sequencing and spatial data analysis. This event wouldn’t have been possible without the amazing Integrated Sciences team and the continued support from our wonderful customers in Australia. 💙 ✨ Next stop: Oz Single Cell kicks off today! Come say hi at our booth and check out our poster to learn more about what’s new with Vizgen. #MERSCOPE #MERFISH #SpatialBiology #SingleCell #OzSingleCell #SpatialGenomics #Vizgen #MERSCOPEUltra #MERFISH2_0

Vizgen is headed to the 2025 Human Cell Atlas General Meeting in Singapore, June 9-11. We’re proud to be silver sponsors for this year’s HCA General Meeting and excited to connect with the global single-cell and spatial genomics community as we work together toward the next phase of atlas development. Visit Vizgen at Booth #2 to learn how MERFISH 2.0™ and the MERSCOPE Ultra™ platform are helping researchers generate high-resolution, high-plex spatial data—even from challenging sample types. Don’t miss George Emanuel, Vizgen’s Scientific Cofounder and VP, Instruments Portfolio, as he presents a technology showcase on June 9 at 4:30 p.m. SGT. George will share real-world examples of how researchers are applying MERFISH 2.0 chemistry to study cellular complexity at scale. We look forward to the conversations, collaboration, and momentum this important event brings. Learn more: https://hubs.ly/Q03mpBq90 #SpatialBiology

As ADC therapies face significant challenges with lack of efficacy, the need for precision biomarker strategies has never been greater. Our Ultivue by Vizgen ADC OmniVUE™ Panels bring together InSituPlex® and STARVUE™ technologies to meet that need with clarity and scale: ➡️Pathology-grade precision across tumor samples, and reproducible intra- and inter-run performance with positive cell density as well as signal intensity. ➡️Quantitative expression analysis of variable expression across cellular compartments, enabling detailed spatial profiling of biomarkers like HER2 and TROP2. ➡️Flexible panel design with a validated menu of over 30 core biomarkers — and custom panels developed in less than 8 weeks. Our ADC OmniVUE™ Panels are built to enable deeper, faster insights for advancing ADC therapeutic development with the consistency clinical researchers need. Learn more and download the solution brief: https://hubs.ly/Q03lHwGP0 #SpatialBiology #ADC #Biomarkers #ClinicalResearch

New Webinar: Explore The Next Era of Spatial Biology with MERFISH 2.0™. Join us on Wednesday, May 28, with Global Engage to explore how Vizgen’s new MERFISH 2.0 chemistry and the MERSCOPE Ultra™ Platform are advancing spatial genomics—unlocking new possibilities for FFPE and archived tissue samples. Alex Genshaft, Product Manager for Reagents & Consumables at Vizgen, will introduce MERFISH 2.0 chemistry and showcase its optimized workflow for robust transcript detection in FFPE tissues. Mark Watson, M.D., Ph.D., Margaret Gladys Smith Professor at Washington University School of Medicine in St. Louis, will present breast cancer datasets generated with MERFISH 2.0 and discuss how spatial genomics is driving new insights into triple-negative breast cancer to aid discovery of novel prognostic biomarkers. Don’t miss this opportunity to see how cutting-edge spatial transcriptomics is transforming both basic and translational research. 📆Date: Wednesday, May 28 🕙Time: 11 am ET | 4 pm BST | 11 pm SST ✏️Register here: https://hubs.ly/Q03mClqJ0 #SpatialBiology #MERFISH

We hope to see you this week at International Spatial Biology 2025 in The Hague, Netherlands. Join Vizgen’s Mickael Ploquin this Friday, May 16 at 9:55 a.m. for: “Extending Spatial Transcriptomics to Challenging Tissues: Enabling Discovery with MERFISH 2.0.” Mickael will highlight how MERFISH 2.0™ extends spatial transcriptomics to more challenging sample types, demonstrating robust performance in FFPE-preserved tissues—advancing research in tumor microenvironments, neuroscience, and beyond. Learn how MERFISH 2.0, combined with the MERSCOPE Ultra™ platform, enables high-plex analysis of up to 1,000 genes, expanding access to spatial genomics for both foundational and translational research. Stop by Table #5 in the expo hall to connect with the Vizgen team and explore the future of spatial biology. Learn more: https://hubs.ly/Q03mptr80 Global Engage #SpatialBiology

Take your spatial biology research to new depths with MERSCOPE Ultra™, now available with new MERFISH 2.0™ chemistry with enhanced RNA anchoring and signal enhancement for higher sensitivity from challenging sample types! 🌟 Expansive 3.0 cm² Imaging Area for larger samples or multiple smaller ones 🔧 Customizable Panels for up to 1,000 genes, with species versatility and scalable imaging areas 🔍 High-resolution imaging from whole tissue sections to single-cell and sub-cellular levels with ≤20 nm precision 💡 Unparalleled Sensitivity to capture RNA transcripts with the highest detection efficiency, even for lowly expressed genes 🔬 Exceptional Optics & Processing Power for speed and performance across a wide dynamic range ⚙️ Powered by MERFISH and MERFISH 2.0 Technology for unmatched sensitivity and resolution 🛠️ Global Technical Support to assist you whenever you need it 📥 Download the Brochure to learn more: https://hubs.ly/Q03lpYdr0 #SpatialGenomics #MERFISH

Sharing our #AACR25 Vizgen-Ultivue posters - Please never hesitate to reach out!