Beatriz Noriega Fernandes, PhD

Beatriz Noriega Fernandes, PhD

Bend, Oregon, United States
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About

Imagine a team of experts, huddled together, developing innovative inhalation therapies…

Activity

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Experience

  • Lonza Graphic

    Lonza

    Bend, Oregon, United States

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    Ticino, Switzerland

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    Lisbon Area, Portugal

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    Lisbon Metropolitan Area

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    Dortmund, North Rhine-Westphalia, Germany

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    Dortmund, North Rhine-Westphalia, Germany

Education

  • Faculty of Pharmacy of the University of Lisbon Graphic

    Faculdade de Farmácia da Universidade de Lisboa

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    Advisors: M. Luisa Corvo & Eunice Costa
    PhD thesis: Dissolution of Dry Powder Inhaler formulations: in vitro / in vivo correlations

    During the my PhD research period, I attended the following courses within the scope of the MedChemTrain PhD program: Chemical Biology; Computational Drug Discovery; Advanced Drug Synthesis; Analytical and Imaging Tools in Drug Discovery; Drug Development; Frontiers in Medicinal Chemistry.

    Additionally, I did a laboratory rotation at Research…

    Advisors: M. Luisa Corvo & Eunice Costa
    PhD thesis: Dissolution of Dry Powder Inhaler formulations: in vitro / in vivo correlations

    During the my PhD research period, I attended the following courses within the scope of the MedChemTrain PhD program: Chemical Biology; Computational Drug Discovery; Advanced Drug Synthesis; Analytical and Imaging Tools in Drug Discovery; Drug Development; Frontiers in Medicinal Chemistry.

    Additionally, I did a laboratory rotation at Research Institute for Medicines (iMed.ULisboa) where I learned and practiced good animal care and handling, while working with the rodents for dry powder inhaler in vivo testing.

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    Activities and Societies: Biological Engineering Student Nucleus, Organizing Biological Engineering Conferences, and Providing Math Tutoring for High School Students. Collaborative Short Film Production with the International Video Association (IVA) at TU Dortmund.

    MSc thesis: Lysozyme Partitioning in Novel Aqueous-two Phase Systems based on Hyperbranched Polymers. In collaboration with TU Dortmund.

    My masters in Biological Engineering was a multi- and cross-disciplinary training in diverse fields including Environment and Energy, Medical Bioengineering, Food Engineering, Industrial Management, Bioinformatics, Systems Biology and Tissue and Cell Culture Engineering.
    It stimulated and promoted the development of skills like autonomy, analytical…

    MSc thesis: Lysozyme Partitioning in Novel Aqueous-two Phase Systems based on Hyperbranched Polymers. In collaboration with TU Dortmund.

    My masters in Biological Engineering was a multi- and cross-disciplinary training in diverse fields including Environment and Energy, Medical Bioengineering, Food Engineering, Industrial Management, Bioinformatics, Systems Biology and Tissue and Cell Culture Engineering.
    It stimulated and promoted the development of skills like autonomy, analytical and critical thinking, flexibility, creativity, adaptability, time management and team work.

    The course is accredited by the portuguese society for engineering professionals.

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    Activities and Societies: Guide Biochemical Open Labs

    The coursework covers: Differential Equations, Complex Analysis, Organic Chemistry, Biochemistry, Molecular Biology, Separation Processes, Genetic Engineering, Enzymatic Engineering, Analytic Chemistry and Transfer Phenomena.

    These courses provide a solid foundation for my studies in Biological Engineering.

Licenses & Certifications

Volunteer Experience

  • Global Mentorship Initiative Graphic

    Mentor

    Global Mentorship Initiative

    - 1 year 6 months

    Education

    At GMI, I provide mentoring to college students across the globe to help them prepare for their initial career roles. My guidance is focused on various business areas:
    - Professional networking and LinkedIn
    - Career planning and SMART goals
    - Global business communication skills
    - Job search and interview best practices
    - How to excel in the workplace environment

  • Instituto Superior Técnico Graphic

    Mentor

    Instituto Superior Técnico

    - 1 year 3 months

    Education

    I volunteer with the Técnico Alumni Mentoring Program, a one-year mentoring program connecting Técnico alumni with current students. In this role, I provide guidance and support, drawing from my experiences to help students navigate their career choices and challenges.

    « Mentoring is a brain to pick, an ear to listen, and a push in the right direction »
    John C. Crosby

Publications

  • Navigating the Development of Dry Powder for Inhalation: A CDMO Perspective

    Pharmaceuticals

    Other authors
    See publication

  • Dry powder inhaler formulation comparison: Study of the role of particle deposition pattern and dissolution

    International Journal of Pharmaceutics

    In this scientific paper, we aimed to utilize a collection and dissolution methodology to differentiate dry powder inhaler (DPI) formulations based on their deposition structures and dissolution profiles in vitro. To achieve this goal, we conducted a case study using Fluticasone Propionate engineered particles and formulated products. The particles were collected using a breath simulator and characterized for their aerodynamic particle size distribution, deposited microstructures, and…

    In this scientific paper, we aimed to utilize a collection and dissolution methodology to differentiate dry powder inhaler (DPI) formulations based on their deposition structures and dissolution profiles in vitro. To achieve this goal, we conducted a case study using Fluticasone Propionate engineered particles and formulated products. The particles were collected using a breath simulator and characterized for their aerodynamic particle size distribution, deposited microstructures, and dissolution/absorption profiles using the DissolvIt® bio-relevant dissolution equipment.

    Other authors
    See publication

  • List of publications on ResearchGate

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    See publication

Patents

  • Dry powder inhaler pharmaceutical composition of coated crystalline dry powder for inhalation

    Filed WO2024009079A1

    The present invention describes a dry powder inhaler pharmaceutical composition comprising one or more active pharmaceutical ingredients (API) coated with one or more force control agents (FCA) with optimized aerodynamic performance by micronizing crystalline API particles to the respirable range and coating the particles with a force control agent. The present invention also id pharmaceutical composition, and its use in medicine.

    Other inventors
    See patent

  • Crystalline pharmaceutical composition for inhalation comprising sugar and lipid composite particles and process for manufacture

    Filed WO2023247952A1

    The present invention describes a pharmaceutical composition comprising composite particles with a controlled aerodynamic particle size distribution, wherein the composite particles comprise one or more active pharmaceutical ingredients (API), at least one sugar and at least one lipid. A process for manufacturing the pharmaceutical composition comprises the steps of: a. Blending API and one or more excipients comprising at least one sugar or at least one lipid, or both at least one sugar and at…

    The present invention describes a pharmaceutical composition comprising composite particles with a controlled aerodynamic particle size distribution, wherein the composite particles comprise one or more active pharmaceutical ingredients (API), at least one sugar and at least one lipid. A process for manufacturing the pharmaceutical composition comprises the steps of: a. Blending API and one or more excipients comprising at least one sugar or at least one lipid, or both at least one sugar and at least one lipid, into a homogeneous powder; b. Reducing the particle size distribution of the blend. The micronized pharmaceutical composition allows for the delivery of crystalline stable API with better aerodynamic properties than the micronized API alone, as well asimproved downstream processing and stability properties.

    Other inventors
    See patent

  • Inhaled Ivermectin

    Filed WO2022170027A1

    The present invention contemplates the use of inhaled ivermectin for use in various viruses and parasitic infections (treatment and/or prophylaxis) that are present or manifest in the lungs or respiratory tract. Exemplary dosing, formulations, devices, and processing techniques are also disclosed herein.

    Other inventors
    See patent

Courses

  • CMC and Regulatory Requirements for Inhalation Drug Products

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  • Coaching for results by Dynargie

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  • German Languagecraft A1

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  • Medicon Valley Inhalation Symposium (MVIS) Workshop 2019

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Languages

  • Portuguese

    Native or bilingual proficiency

  • Spanish

    Native or bilingual proficiency

  • English

    Full professional proficiency

  • Italian

    Elementary proficiency

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