Transporting biological materials, such as DNA/RNA samples, cell lines, and laboratory specimens, requires meticulous attention to detail to ensure safety and compliance. These materials must be packaged to prevent leakage and protect their integrity during transit. Accurate labeling and proper documentation are also essential, including clearly specifying the nature of the materials. #BiologicalLogistics 

🔍 In narcotics identification, every technology has its strengths – and its limits. Raman is powerful, but fluorescence and biological samples can hold it back. Wet chemistry kits are costly, time-consuming, and way too often unreliable. That’s where TactiScan makes the difference: a fast, accurate, and complementary tool that fills the gaps, giving frontline users confidence where other solutions fall short. 💡And with the flexibility to add new substances whenever needed, users stay ahead of emerging threats without compromise. #NarcoticsIdentification #DrugDetection #Forensics #LawEnforcementTechnology #BorderSecurity #PublicSafety #TactiScan #RamanSpectroscopy #NIRTechnology #FieldAnalysis #InnovationInAction #CounterNarcotics

DNA Fingerprinting with PCR In modern DNA fingerprinting, PCR (Polymerase Chain Reaction) is used to make millions of copies of specific DNA regions, even from a tiny sample like a drop of blood or a hair root. Steps in brief: 1. Sample Collection – DNA is isolated from blood, saliva, or hair. 2. PCR Amplification – Short Tandem Repeats (STRs) are copied many times using PCR. 3. Gel Electrophoresis/Capillary Electrophoresis – DNA fragments are separated by size. 4. Band Pattern/Peaks – A unique DNA profile (like a barcode) is generated. Applications: Forensic investigations Paternity testing Identifying victims in disasters Medical diagnostics In simple words: DNA fingerprinting with PCR is like zooming in on your genetic “barcodes” and making enough copies so they can be clearly read #DNAFingerprinting #PCRAmplification #BiotechExplained #ForensicScience #GeneticIdentity #NavyaamiBiotech #Class12Biotech #ScienceSimplified

𝗗𝗼 𝘆𝗼𝘂 𝘄𝗮𝗻𝘁 𝘁𝗼 𝗴𝗲𝘁 𝗿𝗲𝘀𝘂𝗹𝘁𝘀 𝘆𝗼𝘂 𝗰𝗼𝘂𝗹𝗱 𝘁𝗿𝘂𝗹𝘆 𝘁𝗿𝘂𝘀𝘁 𝗳𝗿𝗼𝗺 𝗻𝘂𝗰𝗹𝗲𝗮𝘀𝗲 𝗺𝗼𝗻𝗶𝘁𝗼𝗿𝗶𝗻𝗴?💡 Residual endonucleases are a critical quality attribute in biological manufacturing. If left unchecked, they can compromise purity, safety, and compliance. That’s why routine monitoring is essential in every step. However, existing assays often lack the sensitivity and reproducibility that manufacturers require. 👉 We’ve been working on a solution that delivers 𝘂𝗹𝘁𝗿𝗮-𝘀𝗲𝗻𝘀𝗶𝘁𝗶𝘃𝗲, 𝗽𝗿𝗲𝗰𝗶𝘀𝗲, and 𝗿𝗲𝗽𝗿𝗼𝗱𝘂𝗰𝗶𝗯𝗹𝗲 𝗱𝗲𝘁𝗲𝗰𝘁𝗶𝗼𝗻 across different endonucleases of 𝘚𝘦𝘳𝘳𝘢𝘵𝘪𝘢 𝘮𝘢𝘳𝘤𝘦𝘴𝘤𝘦𝘯𝘴. Stay tuned! Endonuclease ELISA is coming soon. Learn more here → https://lnkd.in/eyJ8T5iq #GeneTherapy #AAV #Bioprocessing

I recently reviewed a case in relation to DNA tests performed on samples from an historic offence. Intimate swabs from the victim had been tested using YDNA profiling and it was written that ‘no reportable’ Y DNA profile was obtained. On examination YDNA markers below the laboratory reporting threshold could be observed. Whilst at a low level the markers were distinct from the background noise, defined, demonstrable and duplicated and were consistent with a person of interest. Whilst the laboratory had followed their evidential reporting guidelines, the opportunity to provide some helpful intelligence appeared to have been missed. Part of the issue may be that investigators may not be aware of the meaning of some of the language that that scientist used in their report. A scientist might think that the use of the term ‘non-reportable’ transparently and adequately conveys what has been observed; however it might be that investigator simply reads this as ‘no profile / no result’ and fails to challenge the position or seek further clarification. Case review should ensure that the intelligence value of any result has been maximised. In my opinion this is particularly relevant to those samples first processed using tests such as SGM or SGM+ where the processes, relating to below threshold DNA markers and manually resolving individual DNA profile components using peak area ratios for submission to the National DNA database, were quite conservative.  DNA mixture interpretation could also be revisited if additional conditioning information which might help resolve the individual component DNA profiles has become available after the initial assessment. Critical samples which have failed to produce a result should also be assessed through a Casework Assessment and Interpretation (CAI) approach so that any unexpected results can be further considered e.g. a no DNA profile result with a positive quantification value can be investigated for possible inhibition and a good quality profile resulting from a poor / degraded sample might allude to the possibility of contamination which could have misdirected an investigation.  Other important review activities include: ·       evaluating work against current scientific approaches and standards to determine if the results can be enhanced and the case progressed  ·       advising on the availability and suitability of retained exhibits / sub-exhibits, to help formulate and deliver the forensic strategy and its objectives.

⌬ Introducing Causal-Chemprop for small molecule property prediction We trained Chemprop and Causal-Chemprop on aqueous solutions from BigSolDB, then predicted the aqueous solubility of a quinolinyltriazole series of MIF inhibitors. The resulting Spearman correlation scores: 🤖 Chemprop: 0.34  🤖 Causal-Chemprop: 0.75 👉 Learn more: https://www.neopolyai.com BigSolDB: 10.26434/chemrxiv-2023-qqslt MIF inhibitors: 10.1021/acsmedchemlett.6b00451

FRAGMENT ANALYZER SYSTEMS • The Fragment Analyzer systems provide automated parallel capillary electrophoresis, delivering accurate and consistent quality control (QC) for nucleic acids. • By automating critical steps such as gel loading and sample injection, the system eliminates common QC bottlenecks, saving time and reducing manual errors. • Its intuitive design ensures ease of use while significantly improving overall lab efficiency. • A wide range of kits enables reliable qualification and quantification of both DNA and RNA samples for diverse applications. • Available in three models with varying throughputs, the systems are designed to meet the specific needs of any laboratory. Visit - https://lnkd.in/dMnksS3e . . #FragmentAnalyzer #NucleicAcids #LabAutomation #CapillaryElectrophoresis #DNATesting #RNATesting #LifeSciences #LabEfficiency #BiotechInnovation #QualityControl

In COMPSAC 2025, we published MuAE as the first mutation-testing framework for autoencoders, introducing a real-world fault taxonomy, validity-preserving mutation operators, and reconstruction-based quality metrics. On CIFAR-10, targeted mutations expose hidden robustness gaps, informing safer AE deployments. #Autoencoders #RobustAI #SoftwareTesting #MutationTesting #MLSafety #COMPSAC #SIUC

DNA extraction involves multiple steps for DNA purification. One of these steps involves adding PCI (25:24:1) which is very effective for DNA purification. Phenol: Denatures proteins and helps separate them from DNA Chloroform: Helps to dissolve lipids and other non-polar compounds Isoamyl alcohol: Reduces foaming and helps to separate phases Warning: Use fume hood as phenol-chloroform is hazardous chemical for health and possess environmental risks.