Troponin in Cardiology: A Clinical Pearl

View profile for okema J Nelson MD

Clinician| MD| Intensivist| Aspiring Emergency Medicine Physician(Cardiology) | Arrhythmology Expert-RCEM-UK | Clinical Researcher | Team lead NUV-HOP🇺🇬🇬🇧🇧🇪|

CARDIOLOGY PEARL🔎‼️ 🔴INFO ON TROPS IN CARDIOLOGY 🧠🫀🔎🫁 👉Troponin is a biomarker of myocardial cell damage, but an elevation does not equate to #ACS. While ACS (e.g., unstable angina, non-ST-elevation MI, or ST-elevation MI) often causes a rising and falling troponin pattern indicative of acute ischemia, other mechanisms like demand ischemia, direct myocardial trauma, or systemic stressors can also lead to leaks from the heart's cytosolic or structural troponin pools. 👉 Unexplained or minor elevations are rare but can occur in conditions such as critical illness or even ultra-endurance exercise, though these are not always tied to irreversible necrosis✍️✅️ 👉Always evaluate troponin in conjunction with clinical history, #ECG changes, and symptoms. A dynamic rising and falling pattern (e.g., ≥20% change) supports ACS or acute injury, while persistently elevated but stable levels suggest chronic conditions like #CKD or stable heart failure. 👉Serial testing (e.g., at 1–3 hours with hs-cTn) helps differentiate, and imaging like echocardiography or MRI may be needed for confirmation (e.g., in suspected myocarditis) 👉Avoid treating non-thrombotic elevations with antiplatelet/antithrombotic agents without evidence of ACS, as this lacks supportive data and may cause harm🚫💔 👉In perioperative settings, monitor high-risk patients (e.g., >65 years or with CV risks) with serial troponins to detect avoidable triggers like hypotension or anemia. #Cardiology #Troponin #MyocardialInjury #AcuteCoronarySyndrome #MedicalEducation #ClinicalPearl #Healthcare #CardiovascularHealth #Diagnosis #Medicine #Cardiology #EmergencyMedicine #ICUSpecialists #AcuteMyocardialInfarction #KillipClassification #ERRiskStratification #Cardiologists #EmergencyPhysicians #ICUNurses #HealthcareProfessionals #Physicianlife #PhysicianOfLinkedlin #EmergencyPhysicians #Emergencymedicine #interns #Medicalstudents

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Emanuel Arias

DO in Medicine Candidate at Lincoln Memorial University-DeBusk College of Osteopathic Medicine

1mo

Great insight. Thanks for sharing

Dr. Atiya Baig

ICU/A&E Physician GP(KSA) ER King Fahd / Shifa PG Resident Pulmonologist Medical/long term/Geriatric/Palliative/Rad.Onco SaudiLicense,PMDC fluent in Arabic/ Infection Biology Sweden Bioinformatics/ Data Analysis .

1mo

Needs a bit more explanation on troponin I and troponin t .Trop T can increase in sepsis Aki and many more conditions but Trop I is significnt in ACS though Troo T rises earlier so in ER setting Trop T is indicative and suggestive whereas Trop I in later stages

Gabriel Hurtado Ponce

Facultativo Especialista de Área (FEA) de Urgencias en Ministerio de Sanidad y Política Social

1mo

It has been an excellent explanation for physicians, especially those of us who work in the Emergency Department. Thanks for sharing

Daniel R.

Registered Cardiac Sonographer BS, ACS, RDCS (AE, PE)

1mo

Excellent!

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Luis Morita

Médico Cardiólogo

1mo

Cardiac amyloid can rise troponin

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Stephanie Doyle

Family Physician and Urgent Care Provider

1mo

Excellent and timely since I’m dealing with a patient now with no known cause for the troponin elevation 

Great content. Thank for sharing.

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