🚨 $1.3B Bet Pays Off: AstraZeneca Just Hit the Jackpot 🚨 AstraZeneca dropped $1.3 BILLION to acquire CinCor and its mid-phase hypertension drug baxdrostat in 2023 and they’ve just nailed a Phase 3 win. 📉 In patients with uncontrolled hypertension: ✅ Statistically significant drop in systolic BP ✅ Success across key secondary endpoints ✅ Well tolerated with a solid safety profile ✅ Signals major potential for resistant hypertension 📈 Baxdrostat also showed strong results in patients who reached SBP <130 mmHg in just 12 weeks. Why it matters: 🔬 Novel mechanism: selectively blocks aldosterone without impacting cortisol 🫀 First real innovation in blood pressure drugs in over 20 years 💥 Massive commercial potential in combo with Farxiga for CKD Remember… this came just months after a failed Phase 2 trial. That flop helped AZ secure better acquisition terms, and now they might be sitting on the next billion-dollar blockbuster. 🛎️I post weekly on major pharma moves, biotech breakthroughs, and validation trends across the U.S. Follow me to stay in the loop! 👇 What’s your take on this move, smart bet or lucky break? #AstraZeneca #CinCor #Baxdrostat #Hypertension #PharmaDeals #DrugDevelopment #ClinicalTrials #LifeSciences #CardiovascularHealth #PharmaNews #GxP #Validation
Awesome News
A first-in-class approach to aldosterone targeting is a big deal especially with such a clean safety profile. Curious to see how it shifts treatment paradigms for resistant hypertension.
Need to do phase 4 superiority study vs low dose spironolactone as add on Rx in refractory HT ?
Thanks for sharing, Harry
Congratulations! Great news, thanks for sharing!👏
Thanks for sharing, Harry
Congratulations! This is a great news!
Wow, what a fascinating development! AstraZeneca's strategic move to acquire CinCor seems to be paying off in a big way. It's impressive how they turned a Phase 2 setback into a major Phase 3 success.
Senior Business Manager | USA | GxP Contract Division
3moThanks for sharing, Harry!