Ayush Suraksha portal tracks ADRs, MLAs in Ayurveda, Siddha, Unani & Homoeopathy systems

Exciting opportunity! Indian Medicines Pharmaceutical Corporation Limited (IMPCL) has extended the tender for the Manufacturing and Supply of Ayush-Satvik Aahar. A great opportunity for reputed manufacturers, relabellers, and branders with valid FSSAI licenses to contribute towards promoting traditional, healthy, and sustainable food systems across India. Tender details & submission: https://impclmohan.nic.in and https://lnkd.in/g7zk9Bs #Ayush #SatvikAahar #Manufacturers #HealthyLiving #Ayurveda

Innovation in Parkinson’s treatment isn’t only about new pharmaceuticals. Sometimes it means revisiting traditional medicines with modern science. One example is Mucuna pruriens — a tropical legume used for centuries in Ayurvedic medicine. Today, with HPLC-standardisation, we can ensure consistent and reliable levels of natural levodopa, making it possible to explore its role in modern Parkinson’s care. What makes this interesting is not just the chemistry, but the methodology of use. Parkinson’s is dynamic — symptoms change, responses evolve, and timing is critical. That’s why we developed the Continuum Method™: a structured framework for introducing and adjusting natural levodopa, focusing on predictability, tracking, and long-term management. This approach has sparked valuable conversations at conferences and within the patient community. It raises questions that feel important for the future of integrative care: How can we bridge traditional remedies and modern standards? What role might natural compounds play in reducing side effects like dyskinesia? And how can we make protocols both clinically rigorous and patient-friendly? I’d be interested to hear your perspective. Are you seeing greater openness to these kinds of integrative approaches in your field?

NRDC offers SCAR Marker technologies designed for the authentication of Ayurvedic, Unani, and herbal drugs, as well as their adulterants. These advanced molecular tools ensure precise quality control, prevent adulteration, and support the standardization of herbal and natural medicine formulations. #NRDCIndia1953 #SCARMarkers #Unani #HerbalMedicine #HerbalAuthentication #DrugStandardization Central Council For Research In Unani Medicine (CCRUM)

Unlocking Smoother Days for Parkinson's Warriors: How Mucuna Pruriens May Reduce Dyskinesia Without Sacrificing Symptom Relief In the world of Parkinson's disease (PD) management, the quest for effective L-DOPA sources that minimize involuntary movements (dyskinesia) is ongoing. Enter Mucuna pruriens – the velvet bean revered in Ayurvedic medicine for its natural L-DOPA content. Emerging research suggests it could offer a gentler alternative to synthetic formulations, providing robust motor benefits with fewer disruptive side effects. Two compelling studies highlight this potential: In a 2004 double-blind crossover trial with PD patients experiencing on-period dyskinesias, high-dose M. pruriens seed powder extended "on" time by 37 minutes compared to standard L-DOPA/carbidopa, with no increase in dyskinesia severity or tolerability issues. This points to its pharmacokinetic edge – higher peak L-DOPA levels without the usual trade-offs. Fast-forward to 2017: A randomized, controlled crossover study of 18 advanced PD patients found high-dose M. pruriens not only matched or exceeded synthetic L-DOPA's motor improvements (e.g., greater UPDRS score reductions at 90-180 minutes) but also led to fewer dyskinesias and adverse events overall. Participants enjoyed longer "on" durations, making daily life more predictable. These findings underscore M. pruriens' promise as an accessible, plant-based option – especially in resource-limited settings. Of course, more large-scale trials are needed, but it's exciting to see nature stepping up in neurological care. Healthcare pros, researchers, or fellow advocates: Have you explored Mucuna in practice? What's your take on integrating botanicals into PD protocols? Let's discuss in the comments!

NTCR–Homeopathic Medical Administration Protocol (Integrating Ayurvedic Logic with Hahnemannian Miasms) CRID: NTCR-HMA-041025-INDIA Timestamp: 04-10-2025, 07:12 AM IST Issued by: NTCR Technologies – Collaborative Research Framework 1. Foundational Principle NTCR integrates Ayurvedic Tridosha (Vata–Pitta–Kapha) with Homeopathic Miasmatic Theory (Psora–Syphilis–Sycosis) to create a step-wise medical administration protocol. This aims at: Clearing toxins (Shodhana) Correcting chronic predispositions (Miasm clearance) Balancing constitution (Dosha alignment) Preventing future diseases

"Navaka Guggulu, a classical Ayurvedic formulation, is valued for its ability to support lipid metabolism, reduce ama (toxic buildup), and aid weight management naturally. Understanding its dosage and proper usage is key to unlocking its therapeutic potential." https://lnkd.in/dcTgMRnV

🌿 “Natural” doesn’t always mean “safe.” A young patient once combined an Ayurvedic formulation with prescribed allopathic medicines — and developed unexpected side effects. Herb-Drug Interaction: Phenytoin & Shankhapushpi In a clinical assessment, an Ayurvedic preparation Shankhapushpi was found to potentially interact with the anticonvulsant phenytoin. This is a clear example of how combining traditional and allopathic medicines can lead to altered pharmacokinetics/drug levels. There are other issues like: ❌ No batch number ❌ No dosage details ❌ No awareness that ADRs apply to traditional medicines too This isn’t an isolated case. Across India, Ayurveda, Siddha, Unani & Homoeopathy (ASU&H) medicines are trusted deeply — but pharmacovigilance is still evolving. This is exactly why Pharmacovigilance in ASU&H (Ayurveda, Siddha, Unani & Homoeopathy) is so critical. ✅ India has built a 3-tier PV network and strengthened formulation standards. 1️⃣ Peripheral PV Centres (PPVCs) — hospitals, colleges & dispensaries where ADRs are first reported 2️⃣ Intermediary PV Centres (IPVCs) — regional hubs that guide, validate & support peripheral centres 3️⃣ National PV Centre (NPC) — at AIIA, New Delhi, which analyses signals & advises regulators 🚨 But challenges remain — low awareness among practitioners, consumers, and companies, complex formulations, and incomplete ADR data. 💡 The way forward: ✔️ Company-level accountability ✔️ PV education in every medical curriculum ✔️ Routine ADR reporting, even for minor events ✔️ Digital tools like AyushSuraksha for seamless reporting Because traditional wisdom deserves modern vigilance. Only then can healthcare be ancient and safe. #Pharmacovigilance #ASUH #DrugSafety #HealthcareInnovation #Ayurveda

In Ayurvedic pharmacology, Mahalaxmi Vilas Ras exemplifies synergy — combining gold bhasma, herbal extracts, and mineral compounds to fortify the immune and respiratory systems. A precise balance of tradition and bio-efficacy for holistic wellbeing. https://lnkd.in/gNm_zgs4

Psoriatic Arthritis & Intrinsic Network Pharmacology (INP): Decoding Disease and Rediscovering Cure Psoriatic Arthritis (PsA) is more than a skin-joint disorder — it’s a network failure connecting immune hyperactivation, keratinocyte proliferation, and chronic inflammation. Through Mother-INP’s 10-Layer Framework, we can visualize PsA as a collapse of the body’s molecular harmony. Failure Nodes (Layer 1-3) Cytokine storm: TNF-α, IL-17A, IL-23, IL-6 Transcriptional chaos: NF-κB, STAT3, mTOR Matrix & bone damage: MMP-3, COX-2, RANKL When these nodes remain unchecked, they create self-sustaining inflammatory attractors — the true root of pain, scaling, and joint stiffness. INP-Guided Restoration (Layer 4-7) Mother-INP identifies phytochemical clusters that re-stabilize these networks: Curcumin, Berberine, Quercetin, Luteolin, Rosmarinic acid, and Guggulsterone — together suppress NF-κB, down-regulate IL-17/IL-23, and normalize STAT3 signaling. Result → reduced cytokine cascade, restored keratinocyte rhythm, and balanced immune-metabolic flow. Ayurvedic Description Classically, PsA aligns with Vāta-Kapha dominance with Rakta dushti — a confluence of Āmavāta and Kushtha roga. Root cause: Āma (metabolic toxins) lodging in sandhi and twak dhatus, triggering shotha (inflammation) and kandu (itch). Ayurvedic Treatment (INP-Mapped) Kaishora Guggulu + Panchtikta Ghrita Guggulu → NF-κB & COX-2 inhibition (Vāta-Kapha-shamana) Arogyavardhini Vati → Hepatic detox, Āma pachana (STAT3 reset) Mahamanjishthadi Kwatha / Khadirarishta → Rakta-shodhana (IL-17/TNF suppression) Bakuchi Taila external → local keratinocyte modulation & Kushtha shamana Mechanism of Action (Mother-INP view) Phytocompounds interact with key targets → Curcumin → COX-2/NF-κB, Berberine → IL-17/JAK-STAT, Quercetin → MMPs/TNF, Rosmarinic acid → IL-23/Nrf2 → restoring the inflammatory attractor (Δ Attractor ≈ +0.76). Conclusion PsA is not incurable — it is restorable. When Ayurvedic tridosha balance meets modern network pharmacology, inflammation transforms into harmony. #IntrinsicNetworkPharmacology #PsoriaticArthritis #Ayurveda #NetworkMedicine #Autoimmune #Inflammation #Phytochemistry #SystemsBiology #HolisticHealing #Curcumin #Berberine #KaishoraGuggulu #Rasayana #MotherINP #HemanthKumarManikyam #NaturalDrugDiscovery #IntegrativeMedicine #AyurvedicResearch #NFkB #IL17 #STAT3 #TNF #RaktaShodhana #Amavata #KushthaRoga

𝐂𝐥𝐨𝐯𝐞𝐬 – 𝐓𝐢𝐧𝐲 𝐁𝐮𝐝𝐬, 𝐆𝐢𝐚𝐧𝐭 𝐁𝐞𝐧𝐞𝐟𝐢𝐭𝐬 Cloves (लौंग) are often overlooked next to pepper or cinnamon. But these tiny aromatic buds have been treasured for centuries - both in Ayurveda and now in modern clinical research. ➔ 𝐓𝐡𝐞 𝐇𝐢𝐝𝐝𝐞𝐧 𝐏𝐨𝐰𝐞𝐫 𝐨𝐟 𝐂𝐥𝐨𝐯𝐞𝐬 𝐄𝐮𝐠𝐞𝐧𝐨𝐥 𝐑𝐢𝐜𝐡𝐧𝐞𝐬𝐬: The main compound in cloves, eugenol, is a powerful anti-inflammatory and antimicrobial agent (Journal of Dentistry, 2006). 𝐏𝐨𝐭𝐞𝐧𝐭 𝐀𝐧𝐭𝐢𝐨𝐱𝐢𝐝𝐚𝐧𝐭𝐬: ORAC values show cloves among the highest antioxidant spices - protecting against cellular damage (USDA, 2010). 𝐃𝐢𝐠𝐞𝐬𝐭𝐢𝐯𝐞 𝐀𝐥𝐥𝐲: Traditional use + modern evidence suggest cloves stimulate digestive enzymes and reduce bloating. 𝐑𝐞𝐬𝐩𝐢𝐫𝐚𝐭𝐨𝐫𝐲 𝐑𝐞𝐥𝐢𝐞𝐟: Used in Ayurvedic formulations for coughs and asthma relief. ➔ 𝐓𝐡𝐞 𝐑𝐞𝐚𝐥 𝐁𝐞𝐧𝐞𝐟𝐢𝐭𝐬 𝐁𝐚𝐜𝐤𝐞𝐝 𝐛𝐲 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 • 𝐎𝐫𝐚𝐥 𝐇𝐞𝐚𝐥𝐭𝐡: Clove oil is still used in dentistry for toothaches and gum infections - proven in multiple clinical studies (PubMed ID: 17583426). • 𝐁𝐥𝐨𝐨𝐝 𝐒𝐮𝐠𝐚𝐫 𝐑𝐞𝐠𝐮𝐥𝐚𝐭𝐢𝐨𝐧: Animal & human studies suggest cloves may improve insulin sensitivity and glucose control (Journal of Natural Medicines, 2012). • 𝐈𝐦𝐦𝐮𝐧𝐞 𝐒𝐮𝐩𝐩𝐨𝐫𝐭: Antimicrobial activity of eugenol shows effectiveness against bacteria and fungi (Journal of Applied Microbiology, 2005). • 𝐇𝐞𝐚𝐫𝐭 & 𝐋𝐢𝐯𝐞𝐫 𝐏𝐫𝐨𝐭𝐞𝐜𝐭𝐢𝐨𝐧: Studies highlight protective effects of clove extracts on cardiovascular and liver health. 👉 From your cup of masala chai to modern nutraceuticals, cloves remind us that the smallest natural gifts often carry the largest health treasures. #Superfoods #SpicesOfIndia #Cloves #NaturalWellness #Ayurveda #FoodScience #HealthAndNutrition #FunctionalFoods #SustainableExports #IndianSpices #GlobalTrade #OrganicLiving #Nutraceuticals #HolisticHealth #WellnessInnovation #Export #Import #foodimporter