📢 EDQM Reference Standards Update – September 2025 As part of our ongoing journey in pharmaceuticals, staying aligned with the latest EDQM reference standard updates is critical. EDQM has announced that the following 17 reference standard batches have been replaced this month: 1. HYOSCINE BUTYLBROMIDE FOR SYSTEM SUITABILITY CRS 2. VALACICLOVIR IMPURITY S CRS 3. ETOPOSIDE FOR SYSTEM SUITABILITY CRS 4. ROCURONIUM FOR PEAK IDENTIFICATION CRS 5. ACEBUTOLOL IMPURITY I CRS 6. ONDANSETRON IMPURITY G CRS 7. FLUNARIZINE FOR SYSTEM SUITABILITY CRS 8. IVERMECTIN CRS 9. CISPLATIN IMPURITY A CRS 10. LATANOPROST CRS 11. CLARITHROMYCIN CRS 12. ALLOPURINOL IMPURITY D CRS 13. METRONIDAZOLE IMPURITY A CRS 14. INDAPAMIDE IMPURITY B CRS 15. FOSFOMYCIN TROMETAMOL CRS 16. LIOTHYRONINE SODIUM CRS 17. DESMOPRESSIN CRS 👉 For complete details, check out the official monthly EDQM newsletter. https://lnkd.in/e_pdV4mS ✨ Regularly following these updates not only ensures regulatory compliance, but also helps laboratories and quality teams maintain confidence in their results which ultimately protecting patients and supporting global health. Let’s keep learning, sharing, and staying up to date together. #Pharmaceuticals #EDQM #Quality #ReferenceStandards
EDQM Reference Standards Update: 17 Batches Replaced
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𝐍𝐢𝐤𝐞𝐭𝐡𝐚𝐦𝐢𝐝𝐞 𝐀𝐏𝐈 𝐌𝐚𝐫𝐤𝐞𝐭 𝐋𝐚𝐭𝐞𝐬𝐭 𝐑𝐞𝐩𝐨𝐫𝐭 𝟐𝟎𝟐𝟓-𝟐𝟎𝟑𝟑 𝐆𝐞𝐭 𝐄𝐱𝐜𝐥𝐮𝐬𝐢𝐯𝐞 𝐒𝐚𝐦𝐩𝐥𝐞 𝐏𝐚𝐠𝐞𝐬 𝐨𝐟 𝐍𝐢𝐤𝐞𝐭𝐡𝐚𝐦𝐢𝐝𝐞 𝐀𝐏𝐈 𝐌𝐚𝐫𝐤𝐞𝐭👉 https://lnkd.in/dYVxFxvK The Nikethamide API Market refers to the global industry involved in the production, supply, and commercialization of Nikethamide as an active pharmaceutical ingredient (API). Nikethamide is primarily used as a respiratory stimulant to counteract respiratory depression caused by anesthesia, narcotic overdose, or certain medical conditions. The market includes high-purity API formulations that meet stringent pharmaceutical standards, catering to manufacturers of injectable drugs, emergency care medications, and hospital-based therapies. Growth in this market is driven by the increasing prevalence of respiratory disorders, rising geriatric population, and growing demand for effective critical care treatments. 𝐊𝐞𝐲𝐏𝐥𝐚𝐲𝐞𝐫𝐬👉 Lu'an Huayuan Pharmaceutical, Jiangsu Wuzhong Pharmaceutical Group Co., Ltd., Beijing Yanjing Pharmaceutical Co., Ltd., Moehs Iberica, Pharma Cure Laboratories, Advacare, Jackson Laboratories Pvt Ltd #NikethamideAPIMarket #NikethamideAPI #Nikethamide #Chemicals #Chemicalnews #Chemicalmarket #chemicalindustry #htfmi #Htf HTF Market Intelligence Consulting Pvt Ltd
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I recently saw a LinkedIn post by DBL Pharmaceuticals about their Halal-certified azithromycin 500 mg. Like many others, after seeing this post, I also wondered, “What does Halal really mean here? There are already many products in the market, so what about those?” When we talk about Halal vs. Haram in medicines, the active ingredient (API) like Azithromycin is not the issue.Because it’s a synthetic chemical, not animal-derived. The real concern is the formulation things like excipients, capsule shells, coating agents, stabilizers, and other additives. Halal certification ensures that: √ No haram substances are used (e.g, pork gelatin, non-Halal glycerin). ◼️ Normal azithromycin tablets are usually safe, since most excipients are synthetic or plant-based. ◼️ Extended-release (XR) or capsule forms may contain gelatin or doubtful ingredients if not Halal-certified. I may think this certification gives extra confidence to patients who want both effective treatment and adherence to their faith. 👉 In cases of medical necessity, non-certified options may still be used but when a Halal alternative exists, I think it is always better to choose that. #Pharmacy #HalalCertified #Pharmaceuticals #DBLPharma #Azithromycin #QualityMedicine
𝐏𝐫𝐞𝐬𝐞𝐧𝐭𝐢𝐧𝐠 𝐁𝐚𝐧𝐠𝐥𝐚𝐝𝐞𝐬𝐡’𝐬 1𝐬𝐭 𝐇𝐚𝐥𝐚𝐥-𝐜𝐞𝐫𝐭𝐢𝐟𝐢𝐞𝐝 𝐀𝐳𝐢𝐭𝐡𝐫𝐨𝐦𝐲𝐜𝐢𝐧 500𝐦𝐠! DBL Pharmaceuticals is proud to offer trusted antibiotic treatment that fully aligns with proven Halal standards. This milestone strengthens our commitment to advancing healthcare that respects the needs and values of every community in Bangladesh. #𝘋𝘉𝘓𝘗𝘩𝘢𝘳𝘮𝘢𝘤𝘦𝘶𝘵𝘪𝘤𝘢𝘭𝘴 #𝘏𝘢𝘭𝘢𝘭𝘊𝘦𝘳𝘵𝘪𝘧𝘪𝘦𝘥 #𝘘𝘶𝘢𝘭𝘪𝘵𝘺𝘔𝘦𝘥𝘪𝘤𝘪𝘯𝘦 #𝘢𝘻𝘪𝘵𝘩𝘳𝘰𝘮𝘺𝘤𝘪𝘯 #𝘥𝘣𝘭𝘱𝘩𝘢𝘳𝘮𝘢 #𝘩𝘢𝘭𝘢𝘭 #𝘢𝘤𝘤𝘶𝘻𝘪𝘵𝘩 #𝘥𝘣𝘭
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A truly strategic move. The "Halal" positioning has always had a deep psychological impact in our market-similar to the breakthrough success of Aromatic Halal Soap in the 1990s. In pharmaceuticals, this approach is even more relevant as several Islamic countries now demand Halal certification for imports. While many brands may already meet the criteria, DBL took the initiative to claim this positioning first. That's a remarkable example of- "forward-thinking marketing"
𝐏𝐫𝐞𝐬𝐞𝐧𝐭𝐢𝐧𝐠 𝐁𝐚𝐧𝐠𝐥𝐚𝐝𝐞𝐬𝐡’𝐬 1𝐬𝐭 𝐇𝐚𝐥𝐚𝐥-𝐜𝐞𝐫𝐭𝐢𝐟𝐢𝐞𝐝 𝐀𝐳𝐢𝐭𝐡𝐫𝐨𝐦𝐲𝐜𝐢𝐧 500𝐦𝐠! DBL Pharmaceuticals is proud to offer trusted antibiotic treatment that fully aligns with proven Halal standards. This milestone strengthens our commitment to advancing healthcare that respects the needs and values of every community in Bangladesh. #𝘋𝘉𝘓𝘗𝘩𝘢𝘳𝘮𝘢𝘤𝘦𝘶𝘵𝘪𝘤𝘢𝘭𝘴 #𝘏𝘢𝘭𝘢𝘭𝘊𝘦𝘳𝘵𝘪𝘧𝘪𝘦𝘥 #𝘘𝘶𝘢𝘭𝘪𝘵𝘺𝘔𝘦𝘥𝘪𝘤𝘪𝘯𝘦 #𝘢𝘻𝘪𝘵𝘩𝘳𝘰𝘮𝘺𝘤𝘪𝘯 #𝘥𝘣𝘭𝘱𝘩𝘢𝘳𝘮𝘢 #𝘩𝘢𝘭𝘢𝘭 #𝘢𝘤𝘤𝘶𝘻𝘪𝘵𝘩 #𝘥𝘣𝘭
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💊 Medicines don’t just heal patients, they also build billion-dollar brands. India’s top 10 selling pharmaceutical products remind us of two truths: 1️⃣ Health needs never stop. 2️⃣ Innovation + trust = long-term market leadership. Whether it’s antibiotics, insulin, liver care, or supplements — these names prove how consistency in value creates impact & dominance. 👉 Future belongs to those who combine science, accessibility, and trust. #PharmaIndustry #HealthcareLeadership #TopBrands #InnovationInHealthcare #FutureOfMedicine #BusinessOfHealth #PharmaLeaders #GrowthMindset
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BAPEN is joining the International Pharmaceutical Federation (FIP) in celebrating #WorldPharmacyWeek to spotlight the vital role pharmacy teams play in delivering safe, effective, and personalised nutritional care. From friendly faces in community pharmacies who notice when a regular may be losing weight, right through to Science Manufacturing Technicians supporting the preparation of parenteral nutrition - we’re proud to recognise the pharmacy workforce in all its forms. 🔗 Read more http://bit.ly/4pBjTxm
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Calcium Carbonate is a widely used active pharmaceutical ingredient (API) known for its role in maintaining bone health and treating conditions related to calcium deficiency. It is commonly utilized in compounded formulations to provide essential calcium supplementation, which is crucial for the development and maintenance of strong bones and teeth. In addition to its bone health benefits, Calcium Carbonate is also effective in managing symptoms of heartburn and indigestion by acting as an antacid. Its versatility and efficacy make it a valuable component in various therapeutic applications, ensuring optimal patient outcomes in both preventative and treatment-focused healthcare settings. With our solid and distinct infrastructure, we, at Mineraria Sacilese SPA, are one of the leading calcium carbonate pharma-grade manufacturers and one of the very few suppliers of active pharmaceutical grade calcium carbonate (API) that uses only superior quality raw materials coming from our own quarries, located in the northeast of Italy, very close to Venice. We also obtained, from the Italian Authority (AIFA), the GMP certificate, which certifies our production quality and which few manufacturers in our line have. Moreover, our API products comply to the most used Pharmacopoeias and they are microbiological tested. Interested? Please contact us at : info@mineraria.it
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This is very big news, and a smart move by the FDA. Ketamine is on the WHO list of essential medicines because it has proven to be a safe and effective anesthetic over 50 years of use. In addition, ketamine shows promise as an antidepressant for treatment resistant depression (when used under appropriate medical supervision, NOT self administration!) Equally if not more exciting, the U.S. military has found that when ketamine is administered in very low, ideally fixed, doses by medics and corpsmen it is an excellent NON-OPIOID analgesic that as effective but safer than morphine for treating severe pain on the battlefield. Based on military and civilian studies, many civilian EMS services are using ketamine “off label” to treat severe pain in emergency situations. For background on this concept, see first box in comments. Congratulations to the FDA and Virginia-based Phlow!
We’re honored to announce that Phlow Corp. has been selected as the ketamine sponsor in the U.S. Food and Drug Administration (FDA) Commissioner’s first-ever National Priority Voucher (CNPV) pilot program. This designation recognizes Phlow’s leadership in advancing U.S.-based manufacturing of essential medicines. The FDA’s CNPV Pilot Program is designed to accelerate the development and regulatory review of projects that address a U.S. public health crisis, strengthen the U.S. pharmaceutical supply chain, and reduce dependence on foreign manufacturing. Earlier this year, Phlow proposed ketamine, a critical medicine widely used as a general anesthetic in both civilian and military medicine settings, for inclusion in the CNPV Pilot Program. With no current domestic ketamine API suppliers, Phlow’s project, in partnership with the U.S. Department of Health and Human Services (HHS) HHS Administration for Strategic Preparedness and Response (ASPR), is intended to establish a fully domestic, end-to-end supply chain, from raw materials to finished dosage form, closing a vital gap in national health security. As part of the pilot, Phlow will leverage the voucher to accelerate FDA review timelines, ensuring the timely and resilient availability of this essential medicine through secure U.S.-based production. Our Nation has suffered from multi-year ketamine shortages, with a notable shortage lasting from February 2018 to August 2025. By advancing U.S.-based API production, Phlow is helping to ensure a more secure, transparent, and reliable supply of this critical medicine while reducing the Nation’s dependence on overseas sources. Read the FDA press release: https://lnkd.in/e7QsK3Aj Read Phlow's press release: https://lnkd.in/eTM9J45j
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Taste masking is crucial in various industries like pharmaceutical, food and cosmetics to make products more palatable. In the pharmaceutical sector, taste masking is one of the prime important criteria, as for few medicines, bitter taste can influence the treatment outcome also. Particularly in the case of protease inhibitors, the bitter taste can highly impact the therapeutic outcome for acquired immunodeficiency syndrome (AIDS)-affected children. Here in this review, we tried to focus on various taste masking strategies like coating, sweeteners, granulation, microencapsulation, solid dispersion, complexation, pH modifiers, rheological modification and fast dissolving approaches towards developing well-tolerable medications for kids, which can simultaneously improve patient compliance and meet the highest possible therapeutic goals. Source: https://lnkd.in/gP7wSmmk
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Calcium Carbonate is a widely used active pharmaceutical ingredient (API) known for its role in maintaining bone health and treating conditions related to calcium deficiency. It is commonly utilized in compounded formulations to provide essential calcium supplementation, which is crucial for the development and maintenance of strong bones and teeth. In addition to its bone health benefits, Calcium Carbonate is also effective in managing symptoms of heartburn and indigestion by acting as an antacid. Its versatility and efficacy make it a valuable component in various therapeutic applications, ensuring optimal patient outcomes in both preventative and treatment-focused healthcare settings. With our solid and distinct infrastructure, we, at Mineraria Sacilese SPA, are one of the leading calcium carbonate pharma-grade manufacturers and one of the very few suppliers of active pharmaceutical grade calcium carbonate (API) that uses only superior quality raw materials coming from our own quarries, located in the northeast of Italy, very close to Venice. We also obtained, from the Italian Authority (AIFA), the GMP certificate, which certifies our production quality and which few manufacturers in our line have. Moreover, our API products comply to the most used Pharmacopoeias and they are microbiological tested. Interested? Please contact us at : info@mineraria.it
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💊 Immediate vs Sustained vs Controlled vs Delayed Release — What’s the Difference? In pharmaceutics, not all tablets are created equal. The way a drug is released in the body can completely change its effectiveness, dosing frequency, and patient compliance. Here’s a quick breakdown 👇 🔹 Immediate Release (IR) – • Drug releases rapidly after administration, giving a quick onset of action. • Example: Paracetamol, Ibuprofen. 🔹 Sustained Release (SR) – • Drug releases gradually to maintain effect for longer duration (8–12 hrs). • Example: Diclofenac SR, Metoprolol SR. 🔹 Controlled Release (CR) – • Drug release rate is precisely controlled to maintain nearly constant plasma concentration for 12–24 hrs. • Example: Nifedipine CR, Theophylline CR. 🔹 Delayed Release (DR) – • Drug release is intentionally delayed until it reaches a specific site (like intestine). • Example: Pantoprazole DR, Omeprazole EC. Each release type serves a unique therapeutic purpose — from rapid pain relief to long-term control and site-specific targeting. 💬 Question: If you were designing a new formulation, which release system would you choose — and why? #Pharmacy #Pharmaceutics #DrugDelivery #PharmaKnowledge #PharmaStudents #PharmaProfessionals #PharmaIndustry #PharmaceuticalScience #ControlledRelease #SustainedRelease #PharmaEducation #FormulationScience #PharmaceuticalDevelopment #HealthcareInnovation
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