In women with multiple sclerosis, disease-modifying therapy management during pregnancy increased relapse risk, particularly in patients receiving natalizumab with prolonged interruption or fingolimod. https://ja.ma/46ZweEt
JAMA Neurology
Book and Periodical Publishing
Chicago, Illinois 28,372 followers
A member of the JAMA Network, which includes JAMA, 11 specialty journals, and JAMA Network Open.
About us
JAMA Neurology is an international peer-reviewed journal for physicians caring for people with neurologic disorders and those interested in the structure and function of the normal and diseased nervous system. JAMA Neurology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications. S. Andrew Josephson, MD, Professor of Neurology and Chair of the Department of Neurology, University of California, San Francisco, is the editor in chief.
- Website
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https://jamanetwork.com/journals/jamaneurology
External link for JAMA Neurology
- Industry
- Book and Periodical Publishing
- Company size
- 1,001-5,000 employees
- Headquarters
- Chicago, Illinois
- Founded
- 1919
- Specialties
- Neurology
Updates
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Editorial: Plasma p-tau217 is a promising yet complementary #Alzheimer biomarker, aiding diagnosis and trial efficiency but not fully replacing CSF and PET, especially in those without cognitive impairment. https://ja.ma/48tY1xU
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Across the JAMA Network, we seek submission of manuscripts describing original research that examines the application of #AI in clinical settings. 🔗 Learn more about submission criteria: https://ja.ma/4nTsUkf
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Using tau PET and plasma p-tau217 biomarkers may refine #Alzheimer trials by tracking disease progression in real-time and anticipating cognitive changes prior to impairment. https://ja.ma/4hhc50a
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From JAMA: Plastics smaller than 5 mm are termed #microplastics, which enter the body primarily through inhalation or ingestion after plastic litter in the environment degrades into smaller plastic fragments. Microplastics are increasingly detected in human tissues, with potential links to cognitive, cardiovascular, and inflammatory outcomes. 📌 Learn more: https://ja.ma/4h8V2gu
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HHV-6 was identified as a rare cause of fulminant acute hemorrhagic leukoencephalitis in an immunocompetent adult. https://ja.ma/48w8Ob0
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In TRAILBLAZER-ALZ 2, reduced amyloid levels after donanemab predicted clinical benefit and biomarker improvements in early symptomatic #AlzheimerDisease, supporting amyloid plaque as a surrogate endpoint for disease progression. https://ja.ma/3J6PZk5
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From JAMA: After mechanical thrombectomy for acute LVO stroke, intra-arterial alteplase increased the rate of excellent 90-day functional outcomes without raising symptomatic intracranial hemorrhage. https://ja.ma/42C50RD
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Among patients with acute ischemic stroke due to large vessel occlusion, general anesthesia for endovascular thrombectomy was associated with better functional recovery and higher reperfusion rates than moderate sedation, informing anesthetic strategy selection in US stroke centers. https://ja.ma/4n49sQt
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In patients with post-dural puncture headache who do not respond to conventional treatment, iatrogenic CSF-venous fistula should be considered as it may necessitate different treatment. https://ja.ma/48Q5V4I
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