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DR Amit S.Mane PG Dept of Rasashastra

This document discusses friability testing of tablets. [1] It describes how a friability tester works by tumbling tablets in a drum for a set number of revolutions and measuring any loss in tablet weight from abrasion. [2] An acceptable friability is typically less than 0.8% weight loss to ensure tablets can withstand forces involved in packaging, shipping and handling. [3] The document provides details on the parts, procedures, and features of friability testers used to standardize and evaluate tablet durability.

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106 views

DR Amit S.Mane PG Dept of Rasashastra

This document discusses friability testing of tablets. [1] It describes how a friability tester works by tumbling tablets in a drum for a set number of revolutions and measuring any loss in tablet weight from abrasion. [2] An acceptable friability is typically less than 0.8% weight loss to ensure tablets can withstand forces involved in packaging, shipping and handling. [3] The document provides details on the parts, procedures, and features of friability testers used to standardize and evaluate tablet durability.

Uploaded by

DrVikas
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PPT, PDF, TXT or read online on Scribd
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by

Dr AMIT S.MANE
PG Dept of Rasashastra
Friability??
Introduction
• Standardization of tablets
Diameter size
Uniformity of weight
Thickness
Hardness
Friability
Percentage of medicament
Rate of disintegration
Digital friability
apparatus
• Digital friability test apparatus is
specially used to determine the
durability of tablets from the time
of production to the time use.
• Friability test is also performed to
evaluate the ability of the tablets
to withstand abrasion in packing,
handling and transporting.
• It is also called as friabilator
Parts of the
Instrument
• Plastic chamber
• Timer
• Partition
Plastic chamber

Chamber

Partition

Mounting block
Tablet
Types

SINGLE DRUM
DOUBLE DRUM
Procedure
• A number of tablets weighed
and placed in tumbling
chamber .
• This chamber rotated for four
minutes or 100 revolutions.
• During each revolution tablets
fall from a distance of six
inches to undergo shock
Cont…

• Each of two acrylic drums


provided with an arm which
carries the tablets along with it
up to specific height and allows
them to fall from specific
height,while the drums are
rotating.
• Thus the tablet rub against each
other without hard impact.
• It is fitted with digital revolution
counter showing the current
Cont…

• The digital LCD screen displays


various important massages
regarding the test like –set
rotations and actual rotations of
test.
• Tablets are weighed before and
after the test and the difference
is weight for particular time prior
indication the rate of abrasion.
Cont…
• After 100 revolutions the
tablet are again weighed
and loss in weight indicates
the friability.
• Acceptable limits of weight
loss should not be more
than 0.8%
Salient features

• Accurate, reliable and stable.


• Instrument for measuring
abrasion and strength of
tablet.
• Sturdy motor to drive drums
at constant speed.
• Powerful, sturdy motor
ensures smooth function.
Microprocessor Friability Test Digital Friability Test Apparatus
Apparatus Model: IN-982 Model No.:IN-902
Product Code : Model:VFT-DV
Bellstone Tablet Friability Test
Apparatus Product Code : BHI-PTM-4530
References.

• Introduction to Pharmaceutics-I
Ashok Gupta
• Pharmaceutics-I R.M.Mehta
• Article - Biological Museum
• Article - Magumps Medical
Equipments
• Article - Rimek Pharmaceutical
Machinery
• Internet
Thank
you….

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