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Lampiran 4 CLSI

This document provides tables listing antibiotics and their interpretive criteria for determining sensitivity, intermediate sensitivity, and resistance for various bacteria according to CLSI standards from 2012. The tables cover Staphylococcus species, Streptococcus pyogenes, Pseudomonas aeruginosa, and Enterobacteriaceae. For each antibiotic and bacterium combination, the minimum inhibitory concentration breakpoints are given in millimeters to categorize isolates as sensitive, intermediate, or resistant.

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Revina Ilka Busri Sikumbang
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© Attribution Non-Commercial (BY-NC)
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883 views4 pages

Lampiran 4 CLSI

This document provides tables listing antibiotics and their interpretive criteria for determining sensitivity, intermediate sensitivity, and resistance for various bacteria according to CLSI standards from 2012. The tables cover Staphylococcus species, Streptococcus pyogenes, Pseudomonas aeruginosa, and Enterobacteriaceae. For each antibiotic and bacterium combination, the minimum inhibitory concentration breakpoints are given in millimeters to categorize isolates as sensitive, intermediate, or resistant.

Uploaded by

Revina Ilka Busri Sikumbang
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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53

Lampiran 6

Tabel Clinical and Laboratory Standards Institute (CLSI)


Tahun 2012
A.

Staphylococcus sp
Antibiotik

Penicillin
Oxacillin (untuk S. aureus dan S.
lugdunensis)
Ampicillin
Methicillin
Nafcillin
Amoxicillin-clavulanic acid
Ampicillin-sulbactam
Piperacillin-tazobactam
Ticarcillin-clavulanic acid
Cefamandole
Cefazolin
Cefepime
Cefmetazole
Cefonicid
Cefoperazone
Cefotaxime
Cefotetan
Ceftazidime
Ceftizoxime
Ceftriaxone
Cefuroxime (parenteral)
Cephalothin
Moxalactam
Cefacior
Cefdinir
Cefpodoxime
Cefprozil
Cefuroxime (oral)
Loracarbef
Doripenem
Ertapenem
Imipenem
Meropenem
Teicoplanin
Gentamicin
Amikacin
Kanamycin
Netilmicin
Tobramycin
Azithromycin
Clarithromycin
Erythromycin

Kriteria Penafsiran Diameter Zona (mm)


Sensitif
Intermediet
Resisten
29
28
13
11-12
10
29
14
13
20
15
18
23
18
18
18
16
18
21
23
16
18
20
21
18
18
23
18
20
21
18
23
18
30
19
16
16
14
15
17
18
15
15
18
18
23

10-13
11-12
12-14
15-17
15-17
15-17
13-15
15-17
16-20
15-22
13-15
15-17
15-19
14-20
15-17
15-17
15-22
15-17
17-19
18-20
15-17
15-22
15-17
16-18
14-15
14-15
11-13
13-14
15-16
14-17
13-14
13-14
14-17
14-17
14-22

28
9
10
19
11
17
22
14
14
14
12
14
15
14
12
14
14
13
14
14
14
14
16
17
14
14
14
15
13
13
10
12
14
13
12
12
13
13
13

54
Telithromycin
Dirithromycin
Tetracycline
Doxycycline
Minocycline
Ciprofloxacin
Levofloxacin
Ofloxacin
Moxifloxacin
Lomefloxacin
Norfloxacin
Enoxacin
Gatifloxacin
Grepafloxacin
Sparfloxacin
Fleroxacin
Nitrofurantoin
Clindamycin
Trimethoprim-sulfamethoxazole
Sulfonamides
Trimethoprim
Chloramphenicol
Rifampin
Quinupristin-dalfopristin
Linezolid

B.

22
19
19
16
19
21
19
18
24
22
17
18
23
18
19
19
17
21
16
17
16
18
20
19
21

19-21
16-18
15-18
13-15
15-18
16-20
16-18
15-17
21-23
19-21
13-16
15-17
20-22
15-17
16-18
16-18
15-16
15-20
11-15
13-16
11-15
13-17
17-19
16-18
-

18
15
14
12
14
15
15
14
20
18
12
14
19
14
15
15
14
14
10
12
10
12
16
15
20

Streptococcus Hemolitikus
Antibiotik

Penicillin
Ampicillin
Cefepime
Cefotaxime
Ceftriaxone
Vancomycin
Erythromycin
Azithromycin
Clarithromycin
Dirithromycin
Tetracycline
Levofloxacin
Ofloxacin
Gatifloxacin
Grepafloxacin
Trovafloxacin
Chloramphenicol
Clindamycin
Quinupristin-dalfopristin
Linezolid

Kriteria Penafsiran Diameter Zona (mm)


Sensitif
Intermediet
Resisten
24
24
24
24
24
17
21
16-20
15
18
14-17
13
21
17-20
16
18
14-17
13
23
19-22
18
17
14-16
13
16
13-15
12
21
18-20
17
19
16-18
15
19
16-18
15
21
18-20
17
19
16-18
15
19
16-18
15
21
-

55
C.

Pseudomonas aeruginosa
Antibiotik

Piperacillin
Ticarcillin
Piperacillin-tazobactam
Ticarcillin-clavulanic acid
Ceftazidime
Cefepime
Aztreonam
Doripenem
Imipenem
Meropenem
Colistin
Polymyxin B
Gentamicin
Tobramycin
Amikacin
Netilmicin
Ciprofloxacin
Levofloxacin
Lomefloxacin
Ofloxacin
Norfloxacin
Gatifloxacin

D.

Kriteria Penafsiran Diameter Zona (mm)


Sensitif
Intermediet
Resisten
21
15-20
14
24
16-23
15
21
15-20
14
24
16-23
15
18
15-17
14
18
15-17
14
22
16-21
15
19
16-18
15
19
16-18
15
19
16-18
15
11
10
12
11
15
13-14
12
15
13-14
12
17
15-16
14
15
13-14
12
21
16-20
15
17
14-16
13
22
19-21
18
16
13-15
12
17
13-16
12
18
15-17
14

Enterobacteriaceae
Antibiotik

Ampicillin
Piperacillin
Mecillinam
Amoxicillin-clavulanic acid
Ampicillin-sulbactam
Piperacillin-tazobactam
Ticarcillin-clavulanate
Cefazolin
Cephalotin
Cefepime
Cefotaxime
Ceftriaxone
Cefotetan
Cefoxitin
Cefuroxime (parenteral)
Ceftazidime
Cefamandole
Cefmetazole
Cefonicid
Cefoperazone

Kriteria Penafsiran Diameter Zona (mm)


Sensitif
Intermediet
Resisten
17
14-16
13
21
18-20
17
15
12-14
11
18
14-17
13
15
12-14
11
21
18-20
17
20
15-19
14
23
20-22
19
18
15-17
14
18
15-17
14
26
23-25
22
23
20-22
19
16
13-15
12
18
15-17
14
18
15-17
14
21
18-20
17
18
15-17
14
16
13-15
12
18
15-17
14
21
16-20
15

56
Ceftizoxime
Moxalactam
Cefuroxime (oral)
Loracarbef
Cefacior
Cefdinir
Cefixime
Cefpodoxime
Cefprozil
Cefetamet
Ceftibuten
Aztreonam
Doripenem
Ertapenem
Imipenem
Meropenem
Gentamicin
Tobramycin
Amikacin
Kanamycin
Netilmicin
Streptomycin
Tetracycline
Doxycycline
Minocycline
Ciprofloxacin
Levofloxacin
Lomefloxacin
Ofloxacin
Norfloxacin
Enoxacin
Gatifloxacin
Gemifloxacin
Grepafloxacin
Fleroxacin
Cinoxacin
Nalidixid acid
Trimethoprimsulfamethoxazole
Sulfonamides
Trimethoprim
Chloramphenicol
Fosfomycin
Nitrofurantoin

25
23
23
18
18
20
19
21
18
18
21
21
23
22
23
23
15
15
17
18
15
15
15
14
16
21
17
22
16
17
18
18
20
18
19
19
19
16

22-24
15-22
15-22
15-17
15-17
17-19
16-18
18-20
15-17
15-17
18-20
18-20
20-22
19-21
20-22
20-22
13-14
13-14
15-16
14-17
13-14
12-14
12-14
11-13
13-15
16-20
14-16
19-21
13-15
13-16
15-17
15-17
16-19
15-17
16-18
15-18
14-18
11-15

21
14
14
14
14
16
15
17
14
14
17
17
19
18
19
19
12
12
14
13
12
11
11
10
12
15
13
18
12
12
14
14
15
14
15
14
13
10

17
16
18
16
17

13-16
11-15
13-17
13-15
15-16

12
10
12
12
14

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