PENICILLIN G SODIUM INJECTION USES

This medication is used to treat a wide variety of bacterial

infections. It is also used to prevent infection of
the heart (bacterial endocarditis) in patients with certain heart
diseases who are having surgery. This medication is known as a
natural penicillinantibiotic. It works by stopping the growth of
bacteria.
How to use penicillin G sodium injection
Depending on your specific product, this medication is given by
injection into a vein or into a muscle. Use exactly as directed by
your doctor. The dosage is based on your medical condition and
response to therapy. For children, the dosage is also based
on weight.
If you are giving this medication to yourself at home, learn all
preparation and usage instructions from your health
care professional. Before using, check this product visually for
particles or discoloration. If either is present, do not use the liquid.
Learn how to store and discard medical supplies safely.
Give aminoglycosides (such as gentamicin) separately from this
medication. Do not mix together in the same IV fluid.
Antibiotics work best when the amount of medicine in your body is
kept at a constant level. Therefore, use this drug at evenly spaced
intervals.
Continue to use this medication until the full prescribed amount is
finished, even if symptoms disappear after a few days. Stopping
the medication too early may allow bacteria to continue to grow,
which may result in a return of the infection.
Tell your doctor if your condition persists or worsens.

Pain/redness/swelling at injection site may occur. If any of these
effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication
because he or she has judged that the benefit to you is greater
than the risk of side effects. Many people using this medication do
not have serious side effects.
Tell your doctor right away if you have any serious side effects,
including: joint/muscle pain, muscle weakness, swelling
of ankles/feet, dark/cloudy urine, extreme tiredness,
fast/slow/irregular heartbeat, new signs of infection (e.g., fever,
persistentsore throat), easy bruising/bleeding, change in the
amount of urine, numbness/tingling of arms/legs, seizures,
uncontrolled movements, confusion.
If used to treat syphilis or other spirochetal infections (e.g., Lyme
disease), this medication may cause a condition known as
Jarisch-Herxheimer reaction. This condition may occur 1 to 2
hours after you receive the medication and can last up to 24
hours. Notify your doctor immediately if you experience any of
these symptoms: fever/chills, muscle pain, worsening
of skin sores, fast heartbeat, fast breathing,dizziness, flushing.
This medication may rarely cause a severe intestinal condition
(Clostridium difficile-associated diarrhea) due to a type of
resistant bacteria. This condition may occur weeks to months
after treatment has stopped. Do not use anti-diarrhea products or
narcotic pain medications if you have any of these symptoms
because these products may make them worse. Tell your doctor
immediately if you develop: persistent diarrhea, abdominal
or stomach pain/cramping, blood/mucus in your stool.
Use of this medication for prolonged or repeated periods may
result in oral thrush or a new vaginal yeast infection. Contact your
doctor if you notice white patches in your mouth, a change
in vaginal discharge, or other new symptoms.
A very serious allergic reaction to this drug is rare. However, get
medical help right away if you notice any symptoms of a serious
allergic reaction, including: rash,itching/swelling (especially of the
face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice
other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may
report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects.
You may report side effects to Health Canada at 1-866-234-2345.

Before using this medication, tell your doctor or pharmacist if you
are allergic to it; or to penicillin or cephalosporin antibiotics; or if
you have any other allergies. This product may contain inactive
ingredients (such as corn for products containing dextrose), which
can cause allergic reactions or other problems. Talk to your
pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your
medical history, especially of: asthma, kidney disease.
Certain products of this medication contain sodium. Consult your
doctor or pharmacist if you are on a salt-restricted diet or if you
have a condition that could be worsened by an increase in salt
intake (e.g., congestive heart failure).
Certain products of this medication contain potassium. Consult
your doctor or pharmacist if you are taking
potassium supplements, salt substitutes containing potassium, or
medications that can increase potassium (e.g., ACE
inhibitors such aslisinopril), or if you have a high potassium level
(hyperkalemia).
Kidney function declines as you grow older. This medication is
removed by the kidneys. Therefore, elderly people may be at
greater risk for side effects while using this drug.
Kidney function is not fully developed in newborns and infants.
This medication is removed by the kidneys. Therefore, newborns
and infants may be at greater risk for side effects while using this
drug.
During pregnancy, this medication should be used only when
clearly needed. Discuss the risks and benefits with your doctor.
This drug passes into breast milk. Consult your doctor before
breast-feeding.

Drug interactions may change how your medications work or
increase your risk for serious side effects. This document does
not contain all possible drug interactions. Keep a list of all the
products you use (including prescription/nonprescription drugs
and herbal products) and share it with your doctor and
pharmacist. Do not start, stop, or change the dosage of any
medicines without your doctor's approval.
Some products that may interact with this drug include: "blood
thinners" (e.g., warfarin), live
bacterial vaccines, methotrexate, NSAIDS (e.g., aspirin,
indomethacin),probenecid, tetracyclines, "water pills"/diuretics
(e.g., furosemide, thiazide diuretics such as hydrochlorothiazide).
Low-dose aspirin should be continued if prescribed by your doctor
for specific medical reasons such as heart attack or stroke
prevention (usually at dosages of 81-325 milligrams per day). Ask
your doctor or pharmacist for more details.
Although most antibiotics probably do not affect hormonal birth
control such as pills, patch, or ring, some antibiotics may
decrease their effectiveness. This could cause pregnancy.
Examples include rifamycins such as rifampin or rifabutin. Be sure
to ask your doctor or pharmacist if you should use additional
reliable birth control methods while using this antibiotic.
This medication may interfere with certain laboratory tests
(including certain urine glucose tests), possibly causing false test
results. Make sure laboratory personnel and all your doctors know
you use this drug.

If overdose is suspected, contact a poison control center or
emergency room immediately. US residents can call their local
poison control center at 1-800-222-1222. Canada residents can
call a provincial poison control center. Symptoms of overdose
may include: seizures, confusion, mental/mood changes (e.g.,
agitation).
NOTES:
Laboratory and/or medical tests (e.g., kidney function, complete
blood count, potassium/sodium levels) may be performed
periodically to monitor your progress or check for side effects.
Consult your doctor for more details.
MISSED DOSE:
For the best possible benefit, it is important to receive each
scheduled dose of this medication as directed. If you miss a dose,
contact your doctor or pharmacist immediately to establish a new
dosing schedule. Do not double the dose to catch up.
STORAGE:
Consult the product instructions and your pharmacist for storage
details. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain
unless instructed to do so. Properly discard this product when it is
expired or no longer needed. Consult your pharmacist or local
waste disposal company.