A patient presented with difficulty breathing due to anaphylaxis. The nurse assessed nasal flaring, increased respiratory rate, restlessness, cyanosis of the nail beds, and cold clammy skin. The patient was diagnosed with ineffective airway clearance secondary to anaphylaxis. The nurse placed the patient in Fowler's position, checked the airway, administered oxygen and epinephrine as needed, and monitored oxygen saturation levels. Once stable, the nurse obtained the patient's medical history and provided health teaching about avoiding allergens and carrying an emergency kit to prevent future anaphylactic reactions.